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Items: 1 to 50 of 59

1.

A New Projection From the Deep Cerebellar Nuclei to the Hippocampus via the Ventrolateral and Laterodorsal Thalamus in Mice.

Bohne P, Schwarz MK, Herlitze S, Mark MD.

Front Neural Circuits. 2019 Aug 9;13:51. doi: 10.3389/fncir.2019.00051. eCollection 2019.

2.

Enhanced mGlu5 Signaling in Excitatory Neurons Promotes Rapid Antidepressant Effects via AMPA Receptor Activation.

Holz A, Mülsch F, Schwarz MK, Hollmann M, Döbrössy MD, Coenen VA, Bartos M, Normann C, Biber K, van Calker D, Serchov T.

Neuron. 2019 Jul 23. pii: S0896-6273(19)30637-3. doi: 10.1016/j.neuron.2019.07.011. [Epub ahead of print]

PMID:
31420117
3.

Rabies virus-mediated connectivity tracing from single neurons.

Schwarz MK, Remy S.

J Neurosci Methods. 2019 Sep 1;325:108365. doi: 10.1016/j.jneumeth.2019.108365. Epub 2019 Jul 19. Review.

PMID:
31330160
4.

The in vivo timeline of differentiation of engrafted human neural progenitor cells.

Vogel S, Schäfer C, Hess S, Folz-Donahue K, Nelles M, Minassian A, Schwarz MK, Kukat C, Ehrlich M, Zaehres H, Kloppenburg P, Hoehn M, Aswendt M.

Stem Cell Res. 2019 May;37:101429. doi: 10.1016/j.scr.2019.101429. Epub 2019 Mar 25.

5.

Light-sheet fluorescence expansion microscopy: fast mapping of neural circuits at super resolution.

Bürgers J, Pavlova I, Rodriguez-Gatica JE, Henneberger C, Oeller M, Ruland JA, Siebrasse JP, Kubitscheck U, Schwarz MK.

Neurophotonics. 2019 Jan;6(1):015005. doi: 10.1117/1.NPh.6.1.015005. Epub 2019 Feb 8.

6.

Aversive stimuli drive hypothalamus-to-habenula excitation to promote escape behavior.

Lecca S, Meye FJ, Trusel M, Tchenio A, Harris J, Schwarz MK, Burdakov D, Georges F, Mameli M.

Elife. 2017 Sep 5;6. pii: e30697. doi: 10.7554/eLife.30697.

7.

Subcellular reorganization and altered phosphorylation of the astrocytic gap junction protein connexin43 in human and experimental temporal lobe epilepsy.

Deshpande T, Li T, Herde MK, Becker A, Vatter H, Schwarz MK, Henneberger C, Steinhäuser C, Bedner P.

Glia. 2017 Nov;65(11):1809-1820. doi: 10.1002/glia.23196. Epub 2017 Aug 10.

PMID:
28795432
8.

The structural and functional evidence for vesicular release from astrocytes in situ.

Bohmbach K, Schwarz MK, Schoch S, Henneberger C.

Brain Res Bull. 2018 Jan;136:65-75. doi: 10.1016/j.brainresbull.2017.01.015. Epub 2017 Jan 22. Review.

PMID:
28122264
9.

Adrenergic Gate Release for Spike Timing-Dependent Synaptic Potentiation.

Liu Y, Cui L, Schwarz MK, Dong Y, Schlüter OM.

Neuron. 2017 Jan 18;93(2):394-408. doi: 10.1016/j.neuron.2016.12.039.

10.

Whole-brain 3D mapping of human neural transplant innervation.

Doerr J, Schwarz MK, Wiedermann D, Leinhaas A, Jakobs A, Schloen F, Schwarz I, Diedenhofen M, Braun NC, Koch P, Peterson DA, Kubitscheck U, Hoehn M, Brüstle O.

Nat Commun. 2017 Jan 19;8:14162. doi: 10.1038/ncomms14162.

11.

Glutamatergic synaptic integration of locomotion speed via septoentorhinal projections.

Justus D, Dalügge D, Bothe S, Fuhrmann F, Hannes C, Kaneko H, Friedrichs D, Sosulina L, Schwarz I, Elliott DA, Schoch S, Bradke F, Schwarz MK, Remy S.

Nat Neurosci. 2017 Jan;20(1):16-19. doi: 10.1038/nn.4447. Epub 2016 Nov 28.

PMID:
27893726
12.

Dysfunction of Somatostatin-Positive Interneurons Associated with Memory Deficits in an Alzheimer's Disease Model.

Schmid LC, Mittag M, Poll S, Steffen J, Wagner J, Geis HR, Schwarz I, Schmidt B, Schwarz MK, Remy S, Fuhrmann M.

Neuron. 2016 Oct 5;92(1):114-125. doi: 10.1016/j.neuron.2016.08.034. Epub 2016 Sep 15.

13.

Shifted pallidal co-release of GABA and glutamate in habenula drives cocaine withdrawal and relapse.

Meye FJ, Soiza-Reilly M, Smit T, Diana MA, Schwarz MK, Mameli M.

Nat Neurosci. 2016 Aug;19(8):1019-24. doi: 10.1038/nn.4334. Epub 2016 Jun 27.

PMID:
27348214
14.

Increased Signaling via Adenosine A1 Receptors, Sleep Deprivation, Imipramine, and Ketamine Inhibit Depressive-like Behavior via Induction of Homer1a.

Serchov T, Clement HW, Schwarz MK, Iasevoli F, Tosh DK, Idzko M, Jacobson KA, de Bartolomeis A, Normann C, Biber K, van Calker D.

Neuron. 2015 Aug 5;87(3):549-62. doi: 10.1016/j.neuron.2015.07.010.

15.

Fluorescent-protein stabilization and high-resolution imaging of cleared, intact mouse brains.

Schwarz MK, Scherbarth A, Sprengel R, Engelhardt J, Theer P, Giese G.

PLoS One. 2015 May 20;10(5):e0124650. doi: 10.1371/journal.pone.0124650. eCollection 2015.

16.

Locomotion, Theta Oscillations, and the Speed-Correlated Firing of Hippocampal Neurons Are Controlled by a Medial Septal Glutamatergic Circuit.

Fuhrmann F, Justus D, Sosulina L, Kaneko H, Beutel T, Friedrichs D, Schoch S, Schwarz MK, Fuhrmann M, Remy S.

Neuron. 2015 Jun 3;86(5):1253-64. doi: 10.1016/j.neuron.2015.05.001. Epub 2015 May 14.

17.
18.

Revealing the secrets of neuronal circuits with recombinant rabies virus technology.

Ginger M, Haberl M, Conzelmann KK, Schwarz MK, Frick A.

Front Neural Circuits. 2013 Jan 24;7:2. doi: 10.3389/fncir.2013.00002. eCollection 2013. Review.

19.

Charting monosynaptic connectivity maps by two-color light-sheet fluorescence microscopy.

Niedworok CJ, Schwarz I, Ledderose J, Giese G, Conzelmann KK, Schwarz MK.

Cell Rep. 2012 Nov 29;2(5):1375-86. doi: 10.1016/j.celrep.2012.10.008. Epub 2012 Nov 8. Erratum in: Cell Rep. 2012 Dec 27;2(6):1774-5.

20.

Homer1 gene products orchestrate Ca(2+)-permeable AMPA receptor distribution and LTP expression.

Rozov A, Zivkovic AR, Schwarz MK.

Front Synaptic Neurosci. 2012 Sep 27;4:4. doi: 10.3389/fnsyn.2012.00004. eCollection 2012.

21.

Glycosaminoglycan analogs as a novel anti-inflammatory strategy.

Severin IC, Soares A, Hantson J, Teixeira M, Sachs D, Valognes D, Scheer A, Schwarz MK, Wells TN, Proudfoot AE, Shaw J.

Front Immunol. 2012 Oct 16;3:293. doi: 10.3389/fimmu.2012.00293. eCollection 2012.

22.

Homer 1 - a new player linking the hypothalamic-pituitary-adrenal axis activity to depression and anxiety.

Grinevich V, Seeburg PH, Schwarz MK, Jezova D.

Endocr Regul. 2012 Jul;46(3):153-9. Review.

PMID:
22808907
23.

Evoked axonal oxytocin release in the central amygdala attenuates fear response.

Knobloch HS, Charlet A, Hoffmann LC, Eliava M, Khrulev S, Cetin AH, Osten P, Schwarz MK, Seeburg PH, Stoop R, Grinevich V.

Neuron. 2012 Feb 9;73(3):553-66. doi: 10.1016/j.neuron.2011.11.030.

24.

Hypertrophy and altered activity of the adrenal cortex in Homer 1 knockout mice.

Grinevich V, Jezova D, Gambaryan S, Illarionova A, Kolleker A, Seeburg PH, Schwarz MK.

Horm Metab Res. 2011 Jul;43(8):551-6. doi: 10.1055/s-0031-1280828. Epub 2011 Jul 19.

PMID:
21773966
25.

Transfection via whole-cell recording in vivo: bridging single-cell physiology, genetics and connectomics.

Rancz EA, Franks KM, Schwarz MK, Pichler B, Schaefer AT, Margrie TW.

Nat Neurosci. 2011 Apr;14(4):527-32. doi: 10.1038/nn.2765. Epub 2011 Feb 20.

26.

Homeostatic scaling requires group I mGluR activation mediated by Homer1a.

Hu JH, Park JM, Park S, Xiao B, Dehoff MH, Kim S, Hayashi T, Schwarz MK, Huganir RL, Seeburg PH, Linden DJ, Worley PF.

Neuron. 2010 Dec 22;68(6):1128-42. doi: 10.1016/j.neuron.2010.11.008.

27.

Metabotropic glutamate receptor 5/Homer interactions underlie stress effects on fear.

Tronson NC, Guzman YF, Guedea AL, Huh KH, Gao C, Schwarz MK, Radulovic J.

Biol Psychiatry. 2010 Dec 1;68(11):1007-15. doi: 10.1016/j.biopsych.2010.09.004.

28.

The p110delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors.

Berndt A, Miller S, Williams O, Le DD, Houseman BT, Pacold JI, Gorrec F, Hon WC, Liu Y, Rommel C, Gaillard P, Rückle T, Schwarz MK, Shokat KM, Shaw JP, Williams RL.

Nat Chem Biol. 2010 Mar;6(3):244. No abstract available.

PMID:
20154668
29.

Anti-chemokine small molecule drugs: a promising future?

Proudfoot AE, Power CA, Schwarz MK.

Expert Opin Investig Drugs. 2010 Mar;19(3):345-55. doi: 10.1517/13543780903535867. Review.

PMID:
20113217
30.

The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors.

Berndt A, Miller S, Williams O, Le DD, Houseman BT, Pacold JI, Gorrec F, Hon WC, Liu Y, Rommel C, Gaillard P, Rückle T, Schwarz MK, Shokat KM, Shaw JP, Williams RL.

Nat Chem Biol. 2010 Feb;6(2):117-24. doi: 10.1038/nchembio.293.

31.

Identification and characterization of novel small molecules as potent inhibitors of the plasmodial calcium-dependent protein kinase 1.

Lemercier G, Fernandez-Montalvan A, Shaw JP, Kugelstadt D, Bomke J, Domostoj M, Schwarz MK, Scheer A, Kappes B, Leroy D.

Biochemistry. 2009 Jul 14;48(27):6379-89. doi: 10.1021/bi9005122.

PMID:
19507895
32.

Rapid, reproducible transduction of select forebrain regions by targeted recombinant virus injection into the neonatal mouse brain.

Pilpel N, Landeck N, Klugmann M, Seeburg PH, Schwarz MK.

J Neurosci Methods. 2009 Aug 30;182(1):55-63. doi: 10.1016/j.jneumeth.2009.05.020. Epub 2009 Jun 6.

PMID:
19505498
33.

Select overexpression of homer1a in dorsal hippocampus impairs spatial working memory.

Celikel T, Marx V, Freudenberg F, Zivkovic A, Resnik E, Hasan MT, Licznerski P, Osten P, Rozov A, Seeburg PH, Schwarz MK.

Front Neurosci. 2007 Oct 15;1(1):97-110. doi: 10.3389/neuro.01.1.1.007.2007. eCollection 2007 Nov.

34.

Discovery of a new class of potent, selective, and orally bioavailable CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.

Crosignani S, Page P, Missotten M, Colovray V, Cleva C, Arrighi JF, Atherall J, Macritchie J, Martin T, Humbert Y, Gaudet M, Pupowicz D, Maio M, Pittet PA, Golzio L, Giachetti C, Rocha C, Bernardinelli G, Filinchuk Y, Scheer A, Schwarz MK, Chollet A.

J Med Chem. 2008 Apr 10;51(7):2227-43. doi: 10.1021/jm701383e. Epub 2008 Mar 5.

PMID:
18318469
35.

Genetic and pharmacological targeting of phosphoinositide 3-kinase-gamma reduces atherosclerosis and favors plaque stability by modulating inflammatory processes.

Fougerat A, Gayral S, Gourdy P, Schambourg A, Rückle T, Schwarz MK, Rommel C, Hirsch E, Arnal JF, Salles JP, Perret B, Breton-Douillon M, Wymann MP, Laffargue M.

Circulation. 2008 Mar 11;117(10):1310-7. doi: 10.1161/CIRCULATIONAHA.107.720466. Epub 2008 Feb 11.

PMID:
18268153
36.

Arrest of preterm labor in rat and mouse by an oral and selective nonprostanoid antagonist of the prostaglandin F2alpha receptor (FP).

Cirillo R, Tos EG, Page P, Missotten M, Quattropani A, Scheer A, Schwarz MK, Chollet A.

Am J Obstet Gynecol. 2007 Jul;197(1):54.e1-9.

PMID:
17618756
37.

Combinatorial expression of alpha- and gamma-protocadherins alters their presenilin-dependent processing.

Bonn S, Seeburg PH, Schwarz MK.

Mol Cell Biol. 2007 Jun;27(11):4121-32. Epub 2007 Apr 2.

38.

Importance of phosphoinositide 3-kinase gamma in the host defense against pneumococcal infection.

Maus UA, Backi M, Winter C, Srivastava M, Schwarz MK, Rückle T, Paton JC, Briles D, Mack M, Welte T, Maus R, Bohle RM, Seeger W, Rommel C, Hirsch E, Lohmeyer J, Preissner KT.

Am J Respir Crit Care Med. 2007 May 1;175(9):958-66. Epub 2007 Feb 22.

PMID:
17322108
39.

PI3Kgamma inhibition: towards an 'aspirin of the 21st century'?

Rückle T, Schwarz MK, Rommel C.

Nat Rev Drug Discov. 2006 Nov;5(11):903-18. Epub 2006 Oct 13. Review.

PMID:
17080027
40.

Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma.

Pomel V, Klicic J, Covini D, Church DD, Shaw JP, Roulin K, Burgat-Charvillon F, Valognes D, Camps M, Chabert C, Gillieron C, Françon B, Perrin D, Leroy D, Gretener D, Nichols A, Vitte PA, Carboni S, Rommel C, Schwarz MK, Rückle T.

J Med Chem. 2006 Jun 29;49(13):3857-71.

PMID:
16789742
41.

Complex, multimodal behavioral profile of the Homer1 knockout mouse.

Jaubert PJ, Golub MS, Lo YY, Germann SL, Dehoff MH, Worley PF, Kang SH, Schwarz MK, Seeburg PH, Berman RF.

Genes Brain Behav. 2007 Mar;6(2):141-54.

42.

Distinct roles for different Homer1 isoforms in behaviors and associated prefrontal cortex function.

Lominac KD, Oleson EB, Pava M, Klugmann M, Schwarz MK, Seeburg PH, During MJ, Worley PF, Kalivas PW, Szumlinski KK.

J Neurosci. 2005 Dec 14;25(50):11586-94.

43.

Discovery and development of a new class of potent, selective, orally active oxytocin receptor antagonists.

Quattropani A, Dorbais J, Covini D, Pittet PA, Colovray V, Thomas RJ, Coxhead R, Halazy S, Scheer A, Missotten M, Ayala G, Bradshaw C, De Raemy-Schenk AM, Nichols A, Cirillo R, Tos EG, Giachetti C, Golzio L, Marinelli P, Church DJ, Barberis C, Chollet A, Schwarz MK.

J Med Chem. 2005 Dec 1;48(24):7882-905.

PMID:
16302826
44.

Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia.

Hetz C, Vitte PA, Bombrun A, Rostovtseva TK, Montessuit S, Hiver A, Schwarz MK, Church DJ, Korsmeyer SJ, Martinou JC, Antonsson B.

J Biol Chem. 2005 Dec 30;280(52):42960-70. Epub 2005 Oct 11. Erratum in: J Biol Chem. 2012 Dec 28;287(53):44108.

45.

Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.

Camps M, Rückle T, Ji H, Ardissone V, Rintelen F, Shaw J, Ferrandi C, Chabert C, Gillieron C, Françon B, Martin T, Gretener D, Perrin D, Leroy D, Vitte PA, Hirsch E, Wymann MP, Cirillo R, Schwarz MK, Rommel C.

Nat Med. 2005 Sep;11(9):936-43. Epub 2005 Aug 28.

46.

PI3Kgamma inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus.

Barber DF, Bartolomé A, Hernandez C, Flores JM, Redondo C, Fernandez-Arias C, Camps M, Rückle T, Schwarz MK, Rodríguez S, Martinez-A C, Balomenos D, Rommel C, Carrera AC.

Nat Med. 2005 Sep;11(9):933-5. Epub 2005 Aug 28.

47.

Behavioral and neurochemical phenotyping of Homer1 mutant mice: possible relevance to schizophrenia.

Szumlinski KK, Lominac KD, Kleschen MJ, Oleson EB, Dehoff MH, Schwarz MK, Seeburg PH, Worley PF, Kalivas PW.

Genes Brain Behav. 2005 Jul;4(5):273-88. Erratum in: Genes Brain Behav. 2005 Nov;4(8):486. Schwartz, MK [corrected to Schwarz, MK]; Seeberg, PH [corrected to Seeburg, PH].

48.

{gamma}-Protocadherins, presenilin-mediated release of C-terminal fragment promotes locus expression.

Hambsch B, Grinevich V, Seeburg PH, Schwarz MK.

J Biol Chem. 2005 Apr 22;280(16):15888-97. Epub 2005 Feb 11.

49.

The selection and design of GPCR ligands: from concept to the clinic.

Ashton M, Charlton MH, Schwarz MK, Thomas RJ, Whittaker M.

Comb Chem High Throughput Screen. 2004 Aug;7(5):441-52. Review.

PMID:
15320711
50.

Chemokine inhibition--why, when, where, which and how?

Johnson Z, Power CA, Weiss C, Rintelen F, Ji H, Ruckle T, Camps M, Wells TN, Schwarz MK, Proudfoot AE, Rommel C.

Biochem Soc Trans. 2004 Apr;32(Pt 2):366-77. Review.

PMID:
15046611

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