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Items: 5


Linking autophagy with inflammation through IRF1 signaling in ER+ breast cancer.

Cook KL, Schwartz-Roberts JL, Baumann WT, Clarke R.

Mol Cell Oncol. 2015 Apr 14;3(1):e1023928. doi: 10.1080/23723556.2015.1023928. eCollection 2016 Jan.


Interferon regulatory factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fate.

Schwartz-Roberts JL, Cook KL, Chen C, Shajahan-Haq AN, Axelrod M, Wärri A, Riggins RB, Jin L, Haddad BR, Kallakury BV, Baumann WT, Clarke R.

Cancer Res. 2015 Mar 15;75(6):1046-55. doi: 10.1158/0008-5472.CAN-14-1851. Epub 2015 Jan 9.


MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer.

Shajahan-Haq AN, Cook KL, Schwartz-Roberts JL, Eltayeb AE, Demas DM, Warri AM, Facey CO, Hilakivi-Clarke LA, Clarke R.

Mol Cancer. 2014 Oct 23;13:239. doi: 10.1186/1476-4598-13-239.


Knockdown of estrogen receptor-α induces autophagy and inhibits antiestrogen-mediated unfolded protein response activation, promoting ROS-induced breast cancer cell death.

Cook KL, Clarke PA, Parmar J, Hu R, Schwartz-Roberts JL, Abu-Asab M, Wärri A, Baumann WT, Clarke R.

FASEB J. 2014 Sep;28(9):3891-905. doi: 10.1096/fj.13-247353. Epub 2014 May 23.


GX15-070 (obatoclax) induces apoptosis and inhibits cathepsin D- and L-mediated autophagosomal lysis in antiestrogen-resistant breast cancer cells.

Schwartz-Roberts JL, Shajahan AN, Cook KL, Wärri A, Abu-Asab M, Clarke R.

Mol Cancer Ther. 2013 Apr;12(4):448-59. doi: 10.1158/1535-7163.MCT-12-0617. Epub 2013 Feb 8.

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