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Items: 1 to 50 of 299

1.

Feature article: Discovery of vascular Rho kinase (ROCK) inhibitory peptides.

Abbasgholizadeh R, Zhang H, Craft JW Jr, Bryan RM Jr, Bark SJ, Briggs JM, Fox RO, Agarkov A, Zimmer WE, Gilbertson SR, Schwartz RJ.

Exp Biol Med (Maywood). 2019 Aug;244(11):940-951. doi: 10.1177/1535370219849581. Epub 2019 May 27. No abstract available.

PMID:
31132884
2.

RERE deficiency leads to decreased expression of GATA4 and the development of ventricular septal defects.

Kim BJ, Zaveri HP, Jordan VK, Hernandez-Garcia A, Jacob DJ, Zamora DL, Yu W, Schwartz RJ, Scott DA.

Dis Model Mech. 2018 Aug 28;11(9). pii: dmm031534. doi: 10.1242/dmm.031534.

3.

C.B-17 SCID mice develop epicardial calcinosis with unaltered cardiac function.

Raghunathan S, Reynolds CL, Schwartz RJ, Stewart MD, McConnell BK.

Fundam Clin Pharmacol. 2019 Feb;33(1):25-30. doi: 10.1111/fcp.12398. Epub 2018 Aug 5.

PMID:
29959870
4.

Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development.

Cho E, Mysliwiec MR, Carlson CD, Ansari A, Schwartz RJ, Lee Y.

J Biol Chem. 2018 Jul 27;293(30):11659-11673. doi: 10.1074/jbc.RA118.002482. Epub 2018 Jun 11.

5.

Correction for Lin et al., "Protein Tyrosine Phosphatase-Like A Regulates Myoblast Proliferation and Differentiation through MyoG and the Cell Cycling Signaling Pathway".

Lin X, Yang X, Li Q, Ma Y, Cui S, He D, Lin X, Schwartz RJ, Chang J.

Mol Cell Biol. 2017 Jul 28;37(16). pii: e00236-17. doi: 10.1128/MCB.00236-17. Print 2017 Aug 15. No abstract available.

6.

HIRA deficiency in muscle fibers causes hypertrophy and susceptibility to oxidative stress.

Valenzuela N, Soibam B, Li L, Wang J, Byers LA, Liu Y, Schwartz RJ, Stewart MD.

J Cell Sci. 2017 Aug 1;130(15):2551-2563. doi: 10.1242/jcs.200642. Epub 2017 Jun 9.

7.

YY1 Expression Is Sufficient for the Maintenance of Cardiac Progenitor Cell State.

Gregoire S, Li G, Sturzu AC, Schwartz RJ, Wu SM.

Stem Cells. 2017 Aug;35(8):1913-1923. doi: 10.1002/stem.2646. Epub 2017 Jun 27.

8.

Electrical Stimulation of Artificial Heart Muscle: A Look Into the Electrophysiologic and Genetic Implications.

Mohamed MA, Islas JF, Schwartz RJ, Birla RK.

ASAIO J. 2017 May/Jun;63(3):333-341. doi: 10.1097/MAT.0000000000000486.

9.

The CSRP2BP histone acetyltransferase drives smooth muscle gene expression.

Ma Y, Li Q, Li A, Wei Y, Long P, Jiang X, Sun F, Weiskirchen R, Wu B, Liang C, Grötzinger J, Wei Y, Yu W, Mercola M, Huang Y, Wang J, Yu Y, Schwartz RJ.

Nucleic Acids Res. 2017 Apr 7;45(6):3046-3058. doi: 10.1093/nar/gkw1227.

10.

Mesp1 Marked Cardiac Progenitor Cells Repair Infarcted Mouse Hearts.

Liu Y, Chen L, Diaz AD, Benham A, Xu X, Wijaya CS, Fa'ak F, Luo W, Soibam B, Azares A, Yu W, Lyu Q, Stewart MD, Gunaratne P, Cooney A, McConnell BK, Schwartz RJ.

Sci Rep. 2016 Aug 19;6:31457. doi: 10.1038/srep31457.

11.

miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification.

Shen X, Soibam B, Benham A, Xu X, Chopra M, Peng X, Yu W, Bao W, Liang R, Azares A, Liu P, Gunaratne PH, Mercola M, Cooney AJ, Schwartz RJ, Liu Y.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9551-6. doi: 10.1073/pnas.1608256113. Epub 2016 Aug 10.

12.

The All-Chemical Approach: A Solution for Converting Fibroblasts Into Myocytes.

Liu Y, Mercola M, Schwartz RJ.

Circ Res. 2016 Aug 5;119(4):505-7. doi: 10.1161/CIRCRESAHA.116.309146. No abstract available.

13.

Regulation of alternative polyadenylation by Nkx2-5 and Xrn2 during mouse heart development.

Nimura K, Yamamoto M, Takeichi M, Saga K, Takaoka K, Kawamura N, Nitta H, Nagano H, Ishino S, Tanaka T, Schwartz RJ, Aburatani H, Kaneda Y.

Elife. 2016 Jun 22;5. pii: e16030. doi: 10.7554/eLife.16030.

14.

Single-Cell Lineage Tracing Reveals that Oriented Cell Division Contributes to Trabecular Morphogenesis and Regional Specification.

Li J, Miao L, Shieh D, Spiotto E, Li J, Zhou B, Paul A, Schwartz RJ, Firulli AB, Singer HA, Huang G, Wu M.

Cell Rep. 2016 Apr 5;15(1):158-170. doi: 10.1016/j.celrep.2016.03.012. Epub 2016 Mar 24.

15.

PKG-1α mediates GATA4 transcriptional activity.

Ma Y, Wang J, Yu Y, Schwartz RJ.

Cell Signal. 2016 Jun;28(6):585-94. doi: 10.1016/j.cellsig.2016.02.019. Epub 2016 Mar 2.

PMID:
26946174
16.

Mouse myofibers lacking the SMYD1 methyltransferase are susceptible to atrophy, internalization of nuclei and myofibrillar disarray.

Stewart MD, Lopez S, Nagandla H, Soibam B, Benham A, Nguyen J, Valenzuela N, Wu HJ, Burns AR, Rasmussen TL, Tucker HO, Schwartz RJ.

Dis Model Mech. 2016 Mar;9(3):347-59. doi: 10.1242/dmm.022491.

17.

Cardiomyocyte-specific conditional knockout of the histone chaperone HIRA in mice results in hypertrophy, sarcolemmal damage and focal replacement fibrosis.

Valenzuela N, Fan Q, Fa'ak F, Soibam B, Nagandla H, Liu Y, Schwartz RJ, McConnell BK, Stewart MD.

Dis Model Mech. 2016 Mar;9(3):335-45. doi: 10.1242/dmm.022889.

18.

Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1.

Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD.

Dev Biol. 2016 Feb 1;410(1):86-97. doi: 10.1016/j.ydbio.2015.12.005. Epub 2015 Dec 11.

19.

Genome-Wide Identification of MESP1 Targets Demonstrates Primary Regulation Over Mesendoderm Gene Activity.

Soibam B, Benham A, Kim J, Weng KC, Yang L, Xu X, Robertson M, Azares A, Cooney AJ, Schwartz RJ, Liu Y.

Stem Cells. 2015 Nov;33(11):3254-65. doi: 10.1002/stem.2111. Epub 2015 Aug 18.

20.

Smyd1 facilitates heart development by antagonizing oxidative and ER stress responses.

Rasmussen TL, Ma Y, Park CY, Harriss J, Pierce SA, Dekker JD, Valenzuela N, Srivastava D, Schwartz RJ, Stewart MD, Tucker HO.

PLoS One. 2015 Mar 24;10(3):e0121765. doi: 10.1371/journal.pone.0121765. eCollection 2015.

21.

Persistent Noggin arrests cardiomyocyte morphogenesis and results in early in utero lethality.

Simmons O, Snider P, Wang J, Schwartz RJ, Chen Y, Conway SJ.

Dev Dyn. 2015 Mar;244(3):457-67. doi: 10.1002/dvdy.24233. Epub 2014 Dec 9.

22.

Functional analysis of limb transcriptional enhancers in the mouse.

Nolte MJ, Wang Y, Deng JM, Swinton PG, Wei C, Guindani M, Schwartz RJ, Behringer RR.

Evol Dev. 2014 Jul-Aug;16(4):207-23. doi: 10.1111/ede.12084. Epub 2014 Jun 11. Erratum in: Evol Dev. 2014 Nov;16(6):397.

23.

Steroid receptor coactivator-2 is a dual regulator of cardiac transcription factor function.

Reineke EL, Benham A, Soibam B, Stashi E, Taegtmeyer H, Entman ML, Schwartz RJ, O'Malley BW.

J Biol Chem. 2014 Jun 20;289(25):17721-31. doi: 10.1074/jbc.M113.539908. Epub 2014 May 8.

24.

Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells.

Liu Y, Kaneda R, Leja TW, Subkhankulova T, Tolmachov O, Minchiotti G, Schwartz RJ, Barahona M, Schneider MD.

Stem Cells. 2014 Jun;32(6):1515-26. doi: 10.1002/stem.1695.

25.

Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation.

Zhao C, Guo H, Li J, Myint T, Pittman W, Yang L, Zhong W, Schwartz RJ, Schwarz JJ, Singer HA, Tallquist MD, Wu M.

Development. 2014 Jan;141(2):281-95. doi: 10.1242/dev.093690. Epub 2013 Dec 11.

26.

Associations between the Rho kinase-1 catalytic and PH domain regulatory unit.

Craft JW Jr, Zhang H, Charendoff MN, Mindrebo JT, Schwartz RJ, Briggs JM.

J Mol Graph Model. 2013 Nov;46:74-82. doi: 10.1016/j.jmgm.2013.09.009. Epub 2013 Oct 4.

PMID:
24149321
27.

Sex ratio, poverty, and concurrent partnerships among men and women in the United States: a multilevel analysis.

Adimora AA, Schoenbach VJ, Taylor EM, Khan MR, Schwartz RJ, Miller WC.

Ann Epidemiol. 2013 Nov;23(11):716-9. doi: 10.1016/j.annepidem.2013.08.002. Epub 2013 Oct 5.

28.

MicroRNA-17-92, a direct Ap-2α transcriptional target, modulates T-box factor activity in orofacial clefting.

Wang J, Bai Y, Li H, Greene SB, Klysik E, Yu W, Schwartz RJ, Williams TJ, Martin JF.

PLoS Genet. 2013;9(9):e1003785. doi: 10.1371/journal.pgen.1003785. Epub 2013 Sep 19. Erratum in: PLoS Genet. 2013 Dec;9(12). doi:10.1371/annotation/90602bc3-5052-49ac-a7fb-33210d7c8b4d.

29.

Inactivation of Cdc42 in neural crest cells causes craniofacial and cardiovascular morphogenesis defects.

Liu Y, Jin Y, Li J, Seto E, Kuo E, Yu W, Schwartz RJ, Blazo M, Zhang SL, Peng X.

Dev Biol. 2013 Nov 15;383(2):239-52. doi: 10.1016/j.ydbio.2013.09.013. Epub 2013 Sep 18.

30.

Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis.

Inagawa M, Nakajima K, Makino T, Ogawa S, Kojima M, Ito S, Ikenishi A, Hayashi T, Schwartz RJ, Nakamura K, Obayashi T, Tachibana M, Shinkai Y, Maeda K, Miyagawa-Tomita S, Takeuchi T.

Mech Dev. 2013 Nov-Dec;130(11-12):519-31. doi: 10.1016/j.mod.2013.07.002. Epub 2013 Jul 24.

31.

Brief report: SRF-dependent MiR-210 silences the sonic hedgehog signaling during cardiopoesis.

Zheng G, Tao Y, Yu W, Schwartz RJ.

Stem Cells. 2013 Oct;31(10):2279-85. doi: 10.1002/stem.1464.

32.

Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries.

Tian X, Hu T, Zhang H, He L, Huang X, Liu Q, Yu W, He L, Yang Z, Zhang Z, Zhong TP, Yang X, Yang Z, Yan Y, Baldini A, Sun Y, Lu J, Schwartz RJ, Evans SM, Gittenberger-de Groot AC, Red-Horse K, Zhou B.

Cell Res. 2013 Sep;23(9):1075-90. doi: 10.1038/cr.2013.83. Epub 2013 Jun 25.

33.

Transient Mesp1 expression: a driver of cardiac cell fate determination.

Liu Y, Schwartz RJ.

Transcription. 2013 May-Jun;4(3):92-6. Epub 2013 Apr 12.

34.

Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity.

Chen H, Zhang W, Sun X, Yoshimoto M, Chen Z, Zhu W, Liu J, Shen Y, Yong W, Li D, Zhang J, Lin Y, Li B, VanDusen NJ, Snider P, Schwartz RJ, Conway SJ, Field LJ, Yoder MC, Firulli AB, Carlesso N, Towbin JA, Shou W.

Development. 2013 May;140(9):1946-57. doi: 10.1242/dev.089920.

35.

Haemogenic endocardium contributes to transient definitive haematopoiesis.

Nakano H, Liu X, Arshi A, Nakashima Y, van Handel B, Sasidharan R, Harmon AW, Shin JH, Schwartz RJ, Conway SJ, Harvey RP, Pashmforoush M, Mikkola HK, Nakano A.

Nat Commun. 2013;4:1564. doi: 10.1038/ncomms2569.

36.

Brief report: Oct4 and canonical Wnt signaling regulate the cardiac lineage factor Mesp1 through a Tcf/Lef-Oct4 composite element.

Li Y, Yu W, Cooney AJ, Schwartz RJ, Liu Y.

Stem Cells. 2013 Jun;31(6):1213-7. doi: 10.1002/stem.1362.

37.

In vivo reflectance confocal microscopy of halo nevus.

Schwartz RJ, Vera K, Navarrete N, Lobos P.

J Cutan Med Surg. 2013 Jan-Feb;17(1):33-8.

PMID:
23364148
38.

Whole animal knockout of smooth muscle alpha-actin does not alter excisional wound healing or the fibroblast-to-myofibroblast transition.

Tomasek JJ, Haaksma CJ, Schwartz RJ, Howard EW.

Wound Repair Regen. 2013 Jan-Feb;21(1):166-76. doi: 10.1111/wrr.12001. Epub 2012 Dec 18.

39.

Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function.

Yoshioka K, Yoshida K, Cui H, Wakayama T, Takuwa N, Okamoto Y, Du W, Qi X, Asanuma K, Sugihara K, Aki S, Miyazawa H, Biswas K, Nagakura C, Ueno M, Iseki S, Schwartz RJ, Okamoto H, Sasaki T, Matsui O, Asano M, Adams RH, Takakura N, Takuwa Y.

Nat Med. 2012 Oct;18(10):1560-9. doi: 10.1038/nm.2928. Epub 2012 Sep 16.

PMID:
22983395
40.

Reprogrammed cardiac fibroblasts to the rescue of heart failure.

Liu Y, Schwartz RJ.

Circ Res. 2012 Sep 14;111(7):831-2. doi: 10.1161/CIRCRESAHA.112.279745. No abstract available.

PMID:
22982872
41.

Mice harboring Gnrhr E90K, a mutation that causes protein misfolding and hypogonadotropic hypogonadism in humans, exhibit testis size reduction and ovulation failure.

Stewart MD, Deng JM, Stewart CA, Mullen RD, Wang Y, Lopez S, Serna MK, Huang CC, Janovick JA, Pask AJ, Schwartz RJ, Conn PM, Behringer RR.

Mol Endocrinol. 2012 Nov;26(11):1847-56. doi: 10.1210/me.2012-1072. Epub 2012 Aug 23.

42.

Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors.

Islas JF, Liu Y, Weng KC, Robertson MJ, Zhang S, Prejusa A, Harger J, Tikhomirova D, Chopra M, Iyer D, Mercola M, Oshima RG, Willerson JT, Potaman VN, Schwartz RJ.

Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):13016-21. doi: 10.1073/pnas.1120299109. Epub 2012 Jul 23.

43.

Epistatic rescue of Nkx2.5 adult cardiac conduction disease phenotypes by prospero-related homeobox protein 1 and HDAC3.

Risebro CA, Petchey LK, Smart N, Gomes J, Clark J, Vieira JM, Yanni J, Dobrzynski H, Davidson S, Zuberi Z, Tinker A, Shui B, Tallini YI, Kotlikoff MI, Miquerol L, Schwartz RJ, Riley PR.

Circ Res. 2012 Jul 6;111(2):e19-31. doi: 10.1161/CIRCRESAHA.111.260695. Epub 2012 May 29.

PMID:
22647876
44.

A cell-autonomous role of Cited2 in controlling myocardial and coronary vascular development.

MacDonald ST, Bamforth SD, Bragança J, Chen CM, Broadbent C, Schneider JE, Schwartz RJ, Bhattacharya S.

Eur Heart J. 2013 Aug;34(32):2557-65. doi: 10.1093/eurheartj/ehs056. Epub 2012 Apr 14.

45.

Targeted expression of Cre recombinase provokes placental-specific DNA recombination in transgenic mice.

Zhou CC, Chang J, Mi T, Abbasi S, Gu D, Huang L, Zhang W, Kellems RE, Schwartz RJ, Xia Y.

PLoS One. 2012;7(2):e29236. doi: 10.1371/journal.pone.0029236. Epub 2012 Feb 17.

46.

Which U.S. medical schools are providing the most physicians for the Appalachian region of the United States?

Baker HH, Pathman DE, Nemitz JW, Boisvert CS, Schwartz RJ, Ridpath LC.

Acad Med. 2012 Apr;87(4):498-505. doi: 10.1097/ACM.0b013e318248f3be.

PMID:
22361793
47.

Conditional ablation of Ezh2 in murine hearts reveals its essential roles in endocardial cushion formation, cardiomyocyte proliferation and survival.

Chen L, Ma Y, Kim EY, Yu W, Schwartz RJ, Qian L, Wang J.

PLoS One. 2012;7(2):e31005. doi: 10.1371/journal.pone.0031005. Epub 2012 Feb 1.

48.

Mechanism of fibrotic cardiomyopathy in mice expressing truncated Rho-associated coiled-coil protein kinase 1.

Yang X, Li Q, Lin X, Ma Y, Yue X, Tao Z, Wang F, Mckeehan WL, Wei L, Schwartz RJ, Chang J.

FASEB J. 2012 May;26(5):2105-16. doi: 10.1096/fj.11-201319. Epub 2012 Jan 25.

49.

Weighing in on heart failure: the role of SERCA2a SUMOylation.

Schwartz RJ, Yeh ET.

Circ Res. 2012 Jan 20;110(2):198-9. doi: 10.1161/RES.0b013e318246f187. No abstract available.

PMID:
22267837
50.

Airways in smooth muscle α-actin null mice experience a compensatory mechanism that modulates their contractile response.

Shardonofsky FR, Moore J, Schwartz RJ, Boriek AM.

J Appl Physiol (1985). 2012 Mar;112(5):898-903. doi: 10.1152/japplphysiol.00417.2011. Epub 2011 Dec 1.

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