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Items: 1 to 50 of 1899

1.

Predicting Splicing from Primary Sequence with Deep Learning.

Jaganathan K, Kyriazopoulou Panagiotopoulou S, McRae JF, Darbandi SF, Knowles D, Li YI, Kosmicki JA, Arbelaez J, Cui W, Schwartz GB, Chow ED, Kanterakis E, Gao H, Kia A, Batzoglou S, Sanders SJ, Farh KK.

Cell. 2019 Jan 14. pii: S0092-8674(18)31629-5. doi: 10.1016/j.cell.2018.12.015. [Epub ahead of print]

PMID:
30661751
2.

New roles for dopamine D2 and D3 receptors in pancreatic beta cell insulin secretion.

Farino ZJ, Morgenstern TJ, Maffei A, Quick M, De Solis AJ, Wiriyasermkul P, Freyberg RJ, Aslanoglou D, Sorisio D, Inbar BP, Free RB, Donthamsetti P, Mosharov EV, Kellendonk C, Schwartz GJ, Sibley DR, Schmauss C, Zeltser LM, Moore H, Harris PE, Javitch JA, Freyberg Z.

Mol Psychiatry. 2019 Jan 9. doi: 10.1038/s41380-018-0344-6. [Epub ahead of print]

PMID:
30626912
3.

Stromal fibroblast growth factor 2 reduces the efficacy of bromodomain inhibitors in uveal melanoma.

Chua V, Orloff M, Teh JL, Sugase T, Liao C, Purwin TJ, Lam BQ, Terai M, Ambrosini G, Carvajal RD, Schwartz G, Sato T, Aplin AE.

EMBO Mol Med. 2019 Jan 4. pii: e9081. doi: 10.15252/emmm.201809081. [Epub ahead of print]

4.

Sorafenib for Advanced and Refractory Desmoid Tumors.

Gounder MM, Mahoney MR, Van Tine BA, Ravi V, Attia S, Deshpande HA, Gupta AA, Milhem MM, Conry RM, Movva S, Pishvaian MJ, Riedel RF, Sabagh T, Tap WD, Horvat N, Basch E, Schwartz LH, Maki RG, Agaram NP, Lefkowitz RA, Mazaheri Y, Yamashita R, Wright JJ, Dueck AC, Schwartz GK.

N Engl J Med. 2018 Dec 20;379(25):2417-2428. doi: 10.1056/NEJMoa1805052.

PMID:
30575484
5.

Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder.

An JY, Lin K, Zhu L, Werling DM, Dong S, Brand H, Wang HZ, Zhao X, Schwartz GB, Collins RL, Currall BB, Dastmalchi C, Dea J, Duhn C, Gilson MC, Klei L, Liang L, Markenscoff-Papadimitriou E, Pochareddy S, Ahituv N, Buxbaum JD, Coon H, Daly MJ, Kim YS, Marth GT, Neale BM, Quinlan AR, Rubenstein JL, Sestan N, State MW, Willsey AJ, Talkowski ME, Devlin B, Roeder K, Sanders SJ.

Science. 2018 Dec 14;362(6420). pii: eaat6576. doi: 10.1126/science.aat6576.

PMID:
30545852
6.

Modifying emergency department electronic prescribing for outpatient opioid analgesia.

Schwartz GD, Harding AM, Donaldson SR, Greene SL.

Emerg Med Australas. 2018 Dec 3. doi: 10.1111/1742-6723.13192. [Epub ahead of print]

PMID:
30508874
7.

A Self-Regulating Gap Junction Network of Amacrine Cells Controls Nitric Oxide Release in the Retina.

Jacoby J, Nath A, Jessen ZF, Schwartz GW.

Neuron. 2018 Dec 5;100(5):1149-1162.e5. doi: 10.1016/j.neuron.2018.09.047. Epub 2018 Oct 25.

PMID:
30482690
8.

Alirocumab Reduces Total Nonfatal Cardiovascular and Fatal Events in the ODYSSEY OUTCOMES Trial.

Szarek M, White HD, Schwartz GG, Alings M, Bhatt DL, Bittner VA, Chiang CE, Diaz R, Edelberg JM, Goodman SG, Hanotin C, Harrington RA, Jukema JW, Kimura T, Kiss RG, Lecorps G, Mahaffey KW, Moryusef A, Pordy R, Roe MT, Tricoci P, Xavier D, Zeiher AM, Steg PG; ODYSSEY OUTCOMES Committees and Investigators.

J Am Coll Cardiol. 2018 Oct 27. pii: S0735-1097(18)38961-7. doi: 10.1016/j.jacc.2018.10.039. [Epub ahead of print]

9.

Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome.

Schwartz GG, Steg PG, Szarek M, Bhatt DL, Bittner VA, Diaz R, Edelberg JM, Goodman SG, Hanotin C, Harrington RA, Jukema JW, Lecorps G, Mahaffey KW, Moryusef A, Pordy R, Quintero K, Roe MT, Sasiela WJ, Tamby JF, Tricoci P, White HD, Zeiher AM; ODYSSEY OUTCOMES Committees and Investigators.

N Engl J Med. 2018 Nov 29;379(22):2097-2107. doi: 10.1056/NEJMoa1801174. Epub 2018 Nov 7.

PMID:
30403574
10.

Oleoylethanolamide differentially regulates glycerolipid synthesis and lipoprotein secretion in intestine and liver.

Pan X, Schwartz GJ, Hussain MM.

J Lipid Res. 2018 Dec;59(12):2349-2359. doi: 10.1194/jlr.M089250. Epub 2018 Oct 28.

PMID:
30369486
11.

Iohexol-measured glomerular filtration rate in children and adolescents with chronic kidney disease: a pilot study comparing venous and finger stick methods.

Staples A, Wong C, Schwartz GJ.

Pediatr Nephrol. 2018 Oct 12. doi: 10.1007/s00467-018-4110-4. [Epub ahead of print]

PMID:
30315406
12.

Baseline and on-statin treatment lipoprotein(a) levels for prediction of cardiovascular events: individual patient-data meta-analysis of statin outcome trials.

Willeit P, Ridker PM, Nestel PJ, Simes J, Tonkin AM, Pedersen TR, Schwartz GG, Olsson AG, Colhoun HM, Kronenberg F, Drechsler C, Wanner C, Mora S, Lesogor A, Tsimikas S.

Lancet. 2018 Oct 13;392(10155):1311-1320. doi: 10.1016/S0140-6736(18)31652-0. Epub 2018 Oct 4.

PMID:
30293769
13.

The authors reply.

Ng DK, Schwartz GJ, Schneider MF, Furth SL, Warady BA.

Kidney Int. 2018 Oct;94(4):828-829. doi: 10.1016/j.kint.2018.06.016. No abstract available.

PMID:
30243319
14.

Clinical value of plasma renin activity and aldosterone concentration in the evaluation of secondary hypertension, a case of reninoma.

Hommos MS, Schwartz GL.

J Am Soc Hypertens. 2018 Sep;12(9):641-643. doi: 10.1016/j.jash.2018.06.001. Epub 2018 Jun 7. No abstract available.

PMID:
30220304
15.

Targeted therapies for pediatric psoriasis.

Schwartz G, Paller AS.

Semin Cutan Med Surg. 2018 Sep;37(3):167-172. doi: 10.12788/j.sder.2018.048.

PMID:
30215634
16.

Typology and Circuitry of Suppressed-by-Contrast Retinal Ganglion Cells.

Jacoby J, Schwartz GW.

Front Cell Neurosci. 2018 Aug 27;12:269. doi: 10.3389/fncel.2018.00269. eCollection 2018. Review.

17.

Receptive field center-surround interactions mediate context-dependent spatial contrast encoding in the retina.

Turner MH, Schwartz GW, Rieke F.

Elife. 2018 Sep 6;7. pii: e38841. doi: 10.7554/eLife.38841.

18.

Cyclin-dependent kinase 4 is a preclinical target for diet-induced obesity.

Iqbal NJ, Lu Z, Liu SM, Schwartz GJ, Chua S Jr, Zhu L.

JCI Insight. 2018 Sep 6;3(17). pii: 123000. doi: 10.1172/jci.insight.123000. [Epub ahead of print]

19.

Classes of ITD Predict Outcomes in AML Patients Treated with FLT3 Inhibitors.

Schwartz GW, Manning B, Zhou Y, Velu P, Bigdeli A, Astles R, Lehman AW, Morrissette JJD, Perl AE, Li M, Carroll M, Faryabi RB.

Clin Cancer Res. 2019 Jan 15;25(2):573-583. doi: 10.1158/1078-0432.CCR-18-0655. Epub 2018 Sep 4.

PMID:
30181385
20.

Major Comorbidities of Atopic Dermatitis: Beyond Allergic Disorders.

Paller A, Jaworski JC, Simpson EL, Boguniewicz M, Russell JJ, Block JK, Tofte S, Dunn JD, Feldman SR, Clark AR, Schwartz G, Eichenfield LF.

Am J Clin Dermatol. 2018 Dec;19(6):821-838. doi: 10.1007/s40257-018-0383-4. Review.

PMID:
30168085
21.

Preclinical Evaluation of Nintedanib, a Triple Angiokinase Inhibitor, in Soft-tissue Sarcoma: Potential Therapeutic Implication for Synovial Sarcoma.

Patwardhan PP, Musi E, Schwartz GK.

Mol Cancer Ther. 2018 Nov;17(11):2329-2340. doi: 10.1158/1535-7163.MCT-18-0319. Epub 2018 Aug 30.

PMID:
30166401
22.

A Phase II Trial of Sorafenib and Dacarbazine for Leiomyosarcoma, Synovial Sarcoma, and Malignant Peripheral Nerve Sheath Tumors.

D'Adamo DR, Dickson MA, Keohan ML, Carvajal RD, Hensley ML, Hirst CM, Ezeoke MO, Ahn L, Qin LX, Antonescu CR, Lefkowitz RA, Maki RG, Schwartz GK, Tap WD.

Oncologist. 2018 Aug 20. pii: theoncologist.2018-0160. doi: 10.1634/theoncologist.2018-0160. [Epub ahead of print]

PMID:
30126857
23.

Preoperative Use of Statins in Carotid Artery Stenting: A Systematic Review and Meta-analysis.

Texakalidis P, Giannopoulos S, Jonnalagadda AK, Chitale RV, Jabbour P, Armstrong EJ, Schwartz GG, Kokkinidis DG.

J Endovasc Ther. 2018 Oct;25(5):624-631. doi: 10.1177/1526602818794030. Epub 2018 Aug 13.

PMID:
30101624
24.

The role of dietary competition in the origination and early diversification of North American euprimates.

Stroik LK, Schwartz GT.

Proc Biol Sci. 2018 Aug 1;285(1884). pii: 20181230. doi: 10.1098/rspb.2018.1230.

PMID:
30068683
25.

Ovarian Cancer Incidence in the U.S. and Toxic Emissions from Pulp and Paper Plants: A Geospatial Analysis.

Hanchette C, Zhang CH, Schwartz GG.

Int J Environ Res Public Health. 2018 Jul 31;15(8). pii: E1619. doi: 10.3390/ijerph15081619.

26.

Effect of Serial Infusions of CER-001, a Pre-β High-Density Lipoprotein Mimetic, on Coronary Atherosclerosis in Patients Following Acute Coronary Syndromes in the CER-001 Atherosclerosis Regression Acute Coronary Syndrome Trial: A Randomized Clinical Trial.

Nicholls SJ, Andrews J, Kastelein JJP, Merkely B, Nissen SE, Ray KK, Schwartz GG, Worthley SG, Keyserling C, Dasseux JL, Griffith L, Kim SW, Janssan A, Di Giovanni G, Pisaniello AD, Scherer DJ, Psaltis PJ, Butters J.

JAMA Cardiol. 2018 Sep 1;3(9):815-822. doi: 10.1001/jamacardio.2018.2121.

PMID:
30046828
27.

Ranking Coal Ash Materials for Their Potential to Leach Arsenic and Selenium: Relative Importance of Ash Chemistry and Site Biogeochemistry.

Schwartz GE, Hower JC, Phillips AL, Rivera N, Vengosh A, Hsu-Kim H.

Environ Eng Sci. 2018 Jul 1;35(7):728-738. doi: 10.1089/ees.2017.0347.

28.

Differential Integration of Transcriptome and Proteome Identifies Pan-Cancer Prognostic Biomarkers.

Schwartz GW, Petrovic J, Zhou Y, Faryabi RB.

Front Genet. 2018 Jun 15;9:205. doi: 10.3389/fgene.2018.00205. eCollection 2018.

29.

YouTube Videos as a Source of Information About Clinical Trials: Observational Study.

Hillyer GC, MacLean SA, Beauchemin M, Basch CH, Schmitt KM, Segall L, Kelsen M, Brogan FL, Schwartz GK.

JMIR Cancer. 2018 Jun 26;4(1):e10060. doi: 10.2196/10060.

30.

The dynamic receptive fields of retinal ganglion cells.

Wienbar S, Schwartz GW.

Prog Retin Eye Res. 2018 Nov;67:102-117. doi: 10.1016/j.preteyeres.2018.06.003. Epub 2018 Jun 23. Review.

PMID:
29944919
31.

Autophagy Regulates the Liver Clock and Glucose Metabolism by Degrading CRY1.

Toledo M, Batista-Gonzalez A, Merheb E, Aoun ML, Tarabra E, Feng D, Sarparanta J, Merlo P, Botrè F, Schwartz GJ, Pessin JE, Singh R.

Cell Metab. 2018 Aug 7;28(2):268-281.e4. doi: 10.1016/j.cmet.2018.05.023. Epub 2018 Jun 21.

PMID:
29937374
32.

Heart Failure After Ischemic Stroke or Transient Ischemic Attack in Insulin-Resistant Patients Without Diabetes Mellitus Treated With Pioglitazone.

Young LH, Viscoli CM, Schwartz GG, Inzucchi SE, Curtis JP, Gorman MJ, Furie KL, Conwit R, Spatz ES, Lovejoy A, Abbott JD, Jacoby DL, Kolansky DM, Ling FS, Pfau SE, Kernan WN; IRIS Investigators.

Circulation. 2018 Sep 18;138(12):1210-1220. doi: 10.1161/CIRCULATIONAHA.118.034763.

PMID:
29934374
33.

Adiponectin, Free Fatty Acids, and Cardiovascular Outcomes in Patients With Type 2 Diabetes and Acute Coronary Syndrome.

Schrieks IC, Nozza A, Stähli BE, Buse JB, Henry RR, Malmberg K, Neal B, Nicholls SJ, Rydén L, Mellbin L, Svensson A, Wedel H, Weichert A, Lincoff AM, Tardif JC, Grobbee DE, Schwartz GG.

Diabetes Care. 2018 Aug;41(8):1792-1800. doi: 10.2337/dc18-0158. Epub 2018 Jun 14.

34.

Roles for gut vagal sensory signals in determining energy availability and energy expenditure.

Schwartz GJ.

Brain Res. 2018 Aug 15;1693(Pt B):151-153. doi: 10.1016/j.brainres.2018.04.004. Review.

PMID:
29903617
35.

Radon and lung cancer: What does the public really know?

Vogeltanz-Holm N, Schwartz GG.

J Environ Radioact. 2018 Dec;192:26-31. doi: 10.1016/j.jenvrad.2018.05.017. Epub 2018 Jun 5. Review.

36.

Impact of race on dose selection of molecular-targeted agents in early-phase oncology trials.

Yokota T, Bendell J, LoRusso P, Tsushima T, Desai V, Kenmotsu H, Watanabe J, Ono A, Murugesan B, Silva J, Naito T, Greenberg J, Kumar P, Wang Y, Jikoh T, Shiga R, Hyman DM, Ho AL, Spriggs DR, Schwartz GK, Gounder MM.

Br J Cancer. 2018 Jun;118(12):1571-1579. doi: 10.1038/s41416-018-0102-1. Epub 2018 May 24.

37.

PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence.

Klein ME, Dickson MA, Antonescu C, Qin LX, Dooley SJ, Barlas A, Manova K, Schwartz GK, Crago AM, Singer S, Koff A, Tap WD.

Oncogene. 2018 Sep;37(37):5066-5078. doi: 10.1038/s41388-018-0332-y. Epub 2018 May 23.

38.

A direct tissue-grafting approach to increasing endogenous brown fat.

Blumenfeld NR, Kang HJ, Fenzl A, Song Z, Chung JJ, Singh R, Johnson R, Karakecili A, Feranil JB, Rossen NS, Zhang V, Jaggi S, McCarty B, Bessler S, Schwartz GJ, Grant R, Korner J, Kiefer FW, Gillette BM, Sia SK.

Sci Rep. 2018 May 21;8(1):7957. doi: 10.1038/s41598-018-25866-y.

39.

Combination of pediatric and adult formulas yield valid glomerular filtration rate estimates in young adults with a history of pediatric chronic kidney disease.

Ng DK, Schwartz GJ, Schneider MF, Furth SL, Warady BA.

Kidney Int. 2018 Jul;94(1):170-177. doi: 10.1016/j.kint.2018.01.034. Epub 2018 May 5.

PMID:
29735307
40.

Timing of ECMO Initiation Impacts Survival in Influenza-Associated ARDS.

Steimer DA, Hernandez O, Mason DP, Schwartz GS.

Thorac Cardiovasc Surg. 2018 May 1. doi: 10.1055/s-0038-1642066. [Epub ahead of print]

PMID:
29715710
41.

Thoracoscopic management of a mediastinal abscess caused by extra-esophageal migration of a metal brush bristle.

Ebrahim A, Still S, Schwartz G.

Proc (Bayl Univ Med Cent). 2018 Mar 12;31(2):192-193. doi: 10.1080/08998280.2017.1416240. eCollection 2018 Apr.

42.

An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder.

Werling DM, Brand H, An JY, Stone MR, Zhu L, Glessner JT, Collins RL, Dong S, Layer RM, Markenscoff-Papadimitriou E, Farrell A, Schwartz GB, Wang HZ, Currall BB, Zhao X, Dea J, Duhn C, Erdman CA, Gilson MC, Yadav R, Handsaker RE, Kashin S, Klei L, Mandell JD, Nowakowski TJ, Liu Y, Pochareddy S, Smith L, Walker MF, Waterman MJ, He X, Kriegstein AR, Rubenstein JL, Sestan N, McCarroll SA, Neale BM, Coon H, Willsey AJ, Buxbaum JD, Daly MJ, State MW, Quinlan AR, Marth GT, Roeder K, Devlin B, Talkowski ME, Sanders SJ.

Nat Genet. 2018 May;50(5):727-736. doi: 10.1038/s41588-018-0107-y. Epub 2018 Apr 26.

43.

Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake.

Jeong JH, Lee DK, Liu SM, Chua SC Jr, Schwartz GJ, Jo YH.

PLoS Biol. 2018 Apr 24;16(4):e2004399. doi: 10.1371/journal.pbio.2004399. eCollection 2018 Apr.

44.

Homeostasis Model Assessment of Insulin Resistance and Survival in Patients With Diabetes and Acute Coronary Syndrome.

Stähli BE, Nozza A, Schrieks IC, Buse JB, Malmberg K, Mellbin L, Neal B, Nicholls SJ, Rydén L, Svensson A, Wedel H, Weichert A, Lincoff AM, Grobbee DE, Tardif JC, Schwartz GG.

J Clin Endocrinol Metab. 2018 Jul 1;103(7):2522-2533. doi: 10.1210/jc.2017-02772.

PMID:
29659887
45.

Membrane-containing virus particles exhibit the mechanics of a composite material for genome protection.

Azinas S, Bano F, Torca I, Bamford DH, Schwartz GA, Esnaola J, Oksanen HM, Richter RP, Abrescia NG.

Nanoscale. 2018 Apr 26;10(16):7769-7779. doi: 10.1039/c8nr00196k.

46.

Evo-devo models of tooth development and the origin of hominoid molar diversity.

Ortiz A, Bailey SE, Schwartz GT, Hublin JJ, Skinner MM.

Sci Adv. 2018 Apr 11;4(4):eaar2334. doi: 10.1126/sciadv.aar2334. eCollection 2018 Apr.

47.

Selumetinib in Combination With Dacarbazine in Patients With Metastatic Uveal Melanoma: A Phase III, Multicenter, Randomized Trial (SUMIT).

Carvajal RD, Piperno-Neumann S, Kapiteijn E, Chapman PB, Frank S, Joshua AM, Piulats JM, Wolter P, Cocquyt V, Chmielowski B, Evans TRJ, Gastaud L, Linette G, Berking C, Schachter J, Rodrigues MJ, Shoushtari AN, Clemett D, Ghiorghiu D, Mariani G, Spratt S, Lovick S, Barker P, Kilgour E, Lai Z, Schwartz GK, Nathan P.

J Clin Oncol. 2018 Apr 20;36(12):1232-1239. doi: 10.1200/JCO.2017.74.1090. Epub 2018 Mar 12. Erratum in: J Clin Oncol. 2018 Dec 10;36(35):3528.

PMID:
29528792
48.

Pazopanib radio-sensitization of human sarcoma tumors.

Wang F, Li H, Markovsky E, Glass R, de Stanchina E, Powell SN, Schwartz GK, Haimovitz-Friedman A.

Oncotarget. 2018 Jan 20;9(10):9311-9324. doi: 10.18632/oncotarget.24281. eCollection 2018 Feb 6.

49.

Estrogen receptor alpha drives mTORC1 inhibitor-induced feedback activation of PI3K/AKT in ER+ breast cancer.

Yang W, Schwartz GN, Marotti JD, Chen V, Traphagen NA, Gui J, Miller TW.

Oncotarget. 2018 Jan 15;9(10):8810-8822. doi: 10.18632/oncotarget.24256. eCollection 2018 Feb 6.

50.

Levodopa improves response inhibition and enhances striatal activation in early-stage Parkinson's disease.

Manza P, Schwartz G, Masson M, Kann S, Volkow ND, Li CR, Leung HC.

Neurobiol Aging. 2018 Jun;66:12-22. doi: 10.1016/j.neurobiolaging.2018.02.003. Epub 2018 Feb 10.

PMID:
29501966

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