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Items: 20

1.

State-of-the-Art 2019 on Gene Therapy for Phenylketonuria.

Grisch-Chan HM, Schwank G, Harding CO, Thöny B.

Hum Gene Ther. 2019 Oct;30(10):1274-1283. doi: 10.1089/hum.2019.111. Epub 2019 Sep 9.

PMID:
31364419
2.

In vitro Generation of CRISPR-Cas9 Complexes with Covalently Bound Repair Templates for Genome Editing in Mammalian Cells.

Savić N, Ringnalda FC, Berk C, Bargsten K, Hall J, Jinek M, Schwank G.

Bio Protoc. 2019 Jan 5;9(1). pii: e3136. doi: 10.21769/BioProtoc.3136.

3.

Treatment of a metabolic liver disease by in vivo genome base editing in adult mice.

Villiger L, Grisch-Chan HM, Lindsay H, Ringnalda F, Pogliano CB, Allegri G, Fingerhut R, Häberle J, Matos J, Robinson MD, Thöny B, Schwank G.

Nat Med. 2018 Oct;24(10):1519-1525. doi: 10.1038/s41591-018-0209-1. Epub 2018 Oct 8.

PMID:
30297904
4.

Growth of Epithelial Organoids in a Defined Hydrogel.

Broguiere N, Isenmann L, Hirt C, Ringel T, Placzek S, Cavalli E, Ringnalda F, Villiger L, Züllig R, Lehmann R, Rogler G, Heim MH, Schüler J, Zenobi-Wong M, Schwank G.

Adv Mater. 2018 Oct;30(43):e1801621. doi: 10.1002/adma.201801621. Epub 2018 Sep 10.

5.

Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies.

Nuciforo S, Fofana I, Matter MS, Blumer T, Calabrese D, Boldanova T, Piscuoglio S, Wieland S, Ringnalda F, Schwank G, Terracciano LM, Ng CKY, Heim MH.

Cell Rep. 2018 Jul 31;24(5):1363-1376. doi: 10.1016/j.celrep.2018.07.001.

6.

Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair.

Savic N, Ringnalda FC, Lindsay H, Berk C, Bargsten K, Li Y, Neri D, Robinson MD, Ciaudo C, Hall J, Jinek M, Schwank G.

Elife. 2018 May 29;7. pii: e33761. doi: 10.7554/eLife.33761.

7.

Tissue-specific mutation accumulation in human adult stem cells during life.

Blokzijl F, de Ligt J, Jager M, Sasselli V, Roerink S, Sasaki N, Huch M, Boymans S, Kuijk E, Prins P, Nijman IJ, Martincorena I, Mokry M, Wiegerinck CL, Middendorp S, Sato T, Schwank G, Nieuwenhuis EE, Verstegen MM, van der Laan LJ, de Jonge J, IJzermans JN, Vries RG, van de Wetering M, Stratton MR, Clevers H, Cuppen E, van Boxtel R.

Nature. 2016 Oct 13;538(7624):260-264. doi: 10.1038/nature19768. Epub 2016 Oct 3.

8.

CRISPR/Cas9-Mediated Genome Editing of Mouse Small Intestinal Organoids.

Schwank G, Clevers H.

Methods Mol Biol. 2016;1422:3-11. doi: 10.1007/978-1-4939-3603-8_1.

PMID:
27246017
9.

Advances in therapeutic CRISPR/Cas9 genome editing.

Savić N, Schwank G.

Transl Res. 2016 Feb;168:15-21. doi: 10.1016/j.trsl.2015.09.008. Epub 2015 Sep 26. Review.

10.

Sequential cancer mutations in cultured human intestinal stem cells.

Drost J, van Jaarsveld RH, Ponsioen B, Zimberlin C, van Boxtel R, Buijs A, Sachs N, Overmeer RM, Offerhaus GJ, Begthel H, Korving J, van de Wetering M, Schwank G, Logtenberg M, Cuppen E, Snippert HJ, Medema JP, Kops GJ, Clevers H.

Nature. 2015 May 7;521(7550):43-7. doi: 10.1038/nature14415. Epub 2015 Apr 29.

PMID:
25924068
11.

Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-γ.

Farin HF, Karthaus WR, Kujala P, Rakhshandehroo M, Schwank G, Vries RG, Kalkhoven E, Nieuwenhuis EE, Clevers H.

J Exp Med. 2014 Jun 30;211(7):1393-405. doi: 10.1084/jem.20130753.

12.

Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients.

Schwank G, Koo BK, Sasselli V, Dekkers JF, Heo I, Demircan T, Sasaki N, Boymans S, Cuppen E, van der Ent CK, Nieuwenhuis EE, Beekman JM, Clevers H.

Cell Stem Cell. 2013 Dec 5;13(6):653-8. doi: 10.1016/j.stem.2013.11.002.

13.

Generation of BAC transgenic epithelial organoids.

Schwank G, Andersson-Rolf A, Koo BK, Sasaki N, Clevers H.

PLoS One. 2013 Oct 18;8(10):e76871. doi: 10.1371/journal.pone.0076871. eCollection 2013.

14.

Comment on "Dynamics of dpp signaling and proliferation control".

Schwank G, Yang SF, Restrepo S, Basler K.

Science. 2012 Jan 27;335(6067):401; author reply 401. doi: 10.1126/science.1210997.

15.

Formation of the long range Dpp morphogen gradient.

Schwank G, Dalessi S, Yang SF, Yagi R, de Lachapelle AM, Affolter M, Bergmann S, Basler K.

PLoS Biol. 2011 Jul;9(7):e1001111. doi: 10.1371/journal.pbio.100111. Epub 2011 Jul 26.

16.

Antagonistic growth regulation by Dpp and Fat drives uniform cell proliferation.

Schwank G, Tauriello G, Yagi R, Kranz E, Koumoutsakos P, Basler K.

Dev Cell. 2011 Jan 18;20(1):123-30. doi: 10.1016/j.devcel.2010.11.007.

17.

Regulation of organ growth by morphogen gradients.

Schwank G, Basler K.

Cold Spring Harb Perspect Biol. 2010 Jan;2(1):a001669. doi: 10.1101/cshperspect.a001669. Review.

18.

Growth regulation by Dpp: an essential role for Brinker and a non-essential role for graded signaling levels.

Schwank G, Restrepo S, Basler K.

Development. 2008 Dec;135(24):4003-13. doi: 10.1242/dev.025635.

19.

Auxin triggers transient local signaling for cell specification in Arabidopsis embryogenesis.

Weijers D, Schlereth A, Ehrismann JS, Schwank G, Kientz M, Jürgens G.

Dev Cell. 2006 Feb;10(2):265-70.

20.

Hypobaric hypoxia: within-subject transition effects in albino rats.

Sterner RT, Schwank GD.

Percept Mot Skills. 1972 Dec;35(3):799-806. No abstract available.

PMID:
4643971

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