Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 177

1.

Nesfatin-1 Acts Centrally to Induce Sympathetic Activation of Brown Adipose Tissue and Non-Shivering Thermogenesis.

Levata L, Dore R, Jöhren O, Schwaninger M, Schulz C, Lehnert H.

Horm Metab Res. 2019 Oct;51(10):678-685. doi: 10.1055/a-0985-4272. Epub 2019 Sep 5.

PMID:
31487748
2.

Antibodies against neural antigens in patients with acute stroke: joint results of three independent cohort studies.

Royl G, Fokou TJ, Chunder R, Isa R, Münte TF, Wandinger KP, Schwaninger M, Herrmann O, Valdueza JM, Brocke J, Willkomm M, Willemsen D, Auffarth GU, Mindorf S, Brix B, Chamorro A, Planas A, Urra X.

J Neurol. 2019 Jul 29. doi: 10.1007/s00415-019-09470-2. [Epub ahead of print]

PMID:
31359201
3.

Brain endothelial specific gene therapy improves experimental Sandhoff disease.

Dogbevia G, Grasshoff H, Othman A, Penno A, Schwaninger M.

J Cereb Blood Flow Metab. 2019 Jul 29:271678X19865917. doi: 10.1177/0271678X19865917. [Epub ahead of print]

PMID:
31357902
4.

Maternally Inherited Differences within Mitochondrial Complex I Control Murine Healthspan.

Hirose M, Schilf P, Zarse K, Busch H, Fuellen G, Jöhren O, Köhling R, König IR, Richer B, Rupp J, Schwaninger M, Seeger K, Sina C, Ristow M, Ibrahim SM.

Genes (Basel). 2019 Jul 13;10(7). pii: E532. doi: 10.3390/genes10070532.

5.

Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1.

Yousef H, Czupalla CJ, Lee D, Chen MB, Burke AN, Zera KA, Zandstra J, Berber E, Lehallier B, Mathur V, Nair RV, Bonanno LN, Yang AC, Peterson T, Hadeiba H, Merkel T, Körbelin J, Schwaninger M, Buckwalter MS, Quake SR, Butcher EC, Wyss-Coray T.

Nat Med. 2019 Jun;25(6):988-1000. doi: 10.1038/s41591-019-0440-4. Epub 2019 May 13.

PMID:
31086348
6.

A Natural mtDNA Polymorphism in Complex III Is a Modifier of Healthspan in Mice.

Hirose M, Künstner A, Schilf P, Tietjen AK, Jöhren O, Huebbe P, Rimbach G, Rupp J, Schwaninger M, Busch H, Ibrahim SM.

Int J Mol Sci. 2019 May 13;20(9). pii: E2359. doi: 10.3390/ijms20092359.

7.

Offers beyond the negotiating dyad: Including the excluded in a network exchange experiment.

Schwaninger M, Neuhofer S, Kittel B.

Soc Sci Res. 2019 Mar;79:258-271. doi: 10.1016/j.ssresearch.2018.10.014. Epub 2018 Oct 26.

PMID:
30857666
8.

Intracellular transport and regulation of transcytosis across the blood-brain barrier.

Villaseñor R, Lampe J, Schwaninger M, Collin L.

Cell Mol Life Sci. 2019 Mar;76(6):1081-1092. doi: 10.1007/s00018-018-2982-x. Epub 2018 Dec 6. Review.

9.

Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons.

Wong R, Lénárt N, Hill L, Toms L, Coutts G, Martinecz B, Császár E, Nyiri G, Papaemmanouil A, Waisman A, Müller W, Schwaninger M, Rothwell N, Francis S, Pinteaux E, Denés A, Allan SM.

Brain Behav Immun. 2019 Feb;76:126-138. doi: 10.1016/j.bbi.2018.11.012. Epub 2018 Nov 16.

10.

Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM.

Park MH, Lee JY, Park KH, Jung IK, Kim KT, Lee YS, Ryu HH, Jeong Y, Kang M, Schwaninger M, Gulbins E, Reichel M, Kornhuber J, Yamaguchi T, Kim HJ, Kim SH, Schuchman EH, Jin HK, Bae JS.

Neuron. 2018 Nov 7;100(3):762. doi: 10.1016/j.neuron.2018.10.038. No abstract available.

PMID:
30408445
11.

Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM.

Park MH, Lee JY, Park KH, Jung IK, Kim KT, Lee YS, Ryu HH, Jeong Y, Kang M, Schwaninger M, Gulbins E, Reichel M, Kornhuber J, Yamaguchi T, Kim HJ, Kim SH, Schuchman EH, Jin HK, Bae JS.

Neuron. 2018 Oct 10;100(1):167-182.e9. doi: 10.1016/j.neuron.2018.09.010. Epub 2018 Sep 27. Erratum in: Neuron. 2018 Nov 7;100(3):762.

PMID:
30269989
12.

The Immunometabolomic Interface Receptor Hydroxycarboxylic Acid Receptor 2 Mediates the Therapeutic Effects of Dimethyl Fumarate in Autoantibody-Induced Skin Inflammation.

Wannick M, Assmann JC, Vielhauer JF, Offermanns S, Zillikens D, Sadik CD, Schwaninger M.

Front Immunol. 2018 Aug 14;9:1890. doi: 10.3389/fimmu.2018.01890. eCollection 2018.

13.

[Detection of drug risks after approval : Methods development for the use of routine statutory health insurance data].

Foraita R, Dijkstra L, Falkenberg F, Garling M, Linder R, Pflock R, Rizkallah MR, Schwaninger M, Wright MN, Pigeot I.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2018 Sep;61(9):1075-1081. doi: 10.1007/s00103-018-2786-z. German.

PMID:
30027343
14.

Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice.

Hirose M, Schilf P, Gupta Y, Zarse K, Künstner A, Fähnrich A, Busch H, Yin J, Wright MN, Ziegler A, Vallier M, Belheouane M, Baines JF, Tautz D, Johann K, Oelkrug R, Mittag J, Lehnert H, Othman A, Jöhren O, Schwaninger M, Prehn C, Adamski J, Shima K, Rupp J, Häsler R, Fuellen G, Köhling R, Ristow M, Ibrahim SM.

Sci Rep. 2018 Apr 12;8(1):5872. doi: 10.1038/s41598-018-24290-6.

15.

Correction to: Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017.

Greenwood J, Hammarlund-Udenaes M, Jones HC, Stitt AW, Vandenbroucke RE, Romero IA, Campbell M, Fricker G, Brodin B, Manninga H, Gaillard PJ, Schwaninger M, Webster C, Wicher KB, Khrestchatisky M.

Fluids Barriers CNS. 2018 Jan 12;15(1):3. doi: 10.1186/s12987-017-0086-x.

16.

The LepR-mediated leptin transport across brain barriers controls food reward.

Di Spiezio A, Sandin ES, Dore R, Müller-Fielitz H, Storck SE, Bernau M, Mier W, Oster H, Jöhren O, Pietrzik CU, Lehnert H, Schwaninger M.

Mol Metab. 2018 Feb;8:13-22. doi: 10.1016/j.molmet.2017.12.001. Epub 2017 Dec 7.

17.

Mitochondrial gene polymorphism is associated with gut microbial communities in mice.

Hirose M, Künstner A, Schilf P, Sünderhauf A, Rupp J, Jöhren O, Schwaninger M, Sina C, Baines JF, Ibrahim SM.

Sci Rep. 2017 Nov 10;7(1):15293. doi: 10.1038/s41598-017-15377-7.

18.

Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017.

Greenwood J, Hammarlund-Udenaes M, Jones HC, Stitt AW, Vandenbroucke RE, Romero IA, Campbell M, Fricker G, Brodin B, Manninga H, Gaillard PJ, Schwaninger M, Webster C, Wicher KB, Khrestchatisky M.

Fluids Barriers CNS. 2017 Nov 7;14(1):31. doi: 10.1186/s12987-017-0079-9. Erratum in: Fluids Barriers CNS. 2018 Jan 12;15(1):3.

19.

Tanycytes control the hormonal output of the hypothalamic-pituitary-thyroid axis.

Müller-Fielitz H, Stahr M, Bernau M, Richter M, Abele S, Krajka V, Benzin A, Wenzel J, Kalies K, Mittag J, Heuer H, Offermanns S, Schwaninger M.

Nat Commun. 2017 Sep 7;8(1):484. doi: 10.1038/s41467-017-00604-6.

20.

Involvement of interleukin-1 type 1 receptors in lipopolysaccharide-induced sickness responses.

Matsuwaki T, Shionoya K, Ihnatko R, Eskilsson A, Kakuta S, Dufour S, Schwaninger M, Waisman A, Müller W, Pinteaux E, Engblom D, Blomqvist A.

Brain Behav Immun. 2017 Nov;66:165-176. doi: 10.1016/j.bbi.2017.06.013. Epub 2017 Jun 24.

21.

Gene therapy decreases seizures in a model of Incontinentia pigmenti.

Dogbevia GK, Töllner K, Körbelin J, Bröer S, Ridder DA, Grasshoff H, Brandt C, Wenzel J, Straub BK, Trepel M, Löscher W, Schwaninger M.

Ann Neurol. 2017 Jul;82(1):93-104. doi: 10.1002/ana.24981.

PMID:
28628231
22.

Isolation and Cultivation of Primary Brain Endothelial Cells from Adult Mice.

Assmann JC, Müller K, Wenzel J, Walther T, Brands J, Thornton P, Allan SM, Schwaninger M.

Bio Protoc. 2017 May 20;7(10). pii: e2294. doi: 10.21769/BioProtoc.2294.

23.

Endothelial TLR4 and the microbiome drive cerebral cavernous malformations.

Tang AT, Choi JP, Kotzin JJ, Yang Y, Hong CC, Hobson N, Girard R, Zeineddine HA, Lightle R, Moore T, Cao Y, Shenkar R, Chen M, Mericko P, Yang J, Li L, Tanes C, Kobuley D, Võsa U, Whitehead KJ, Li DY, Franke L, Hart B, Schwaninger M, Henao-Mejia J, Morrison L, Kim H, Awad IA, Zheng X, Kahn ML.

Nature. 2017 May 18;545(7654):305-310. doi: 10.1038/nature22075. Epub 2017 May 10.

24.

Immune-Induced Fever Is Dependent on Local But Not Generalized Prostaglandin E2 Synthesis in the Brain.

Eskilsson A, Matsuwaki T, Shionoya K, Mirrasekhian E, Zajdel J, Schwaninger M, Engblom D, Blomqvist A.

J Neurosci. 2017 May 10;37(19):5035-5044. doi: 10.1523/JNEUROSCI.3846-16.2017. Epub 2017 Apr 24.

25.

New Insight Into the Pathogenesis of Cerebral Small-Vessel Diseases.

Müller K, Courtois G, Ursini MV, Schwaninger M.

Stroke. 2017 Feb;48(2):520-527. doi: 10.1161/STROKEAHA.116.012888. Epub 2017 Jan 12. Review. No abstract available.

PMID:
28082670
26.

Daring the Challenge and Thinking Big: The Value of Early Process RD.

Abele S, Funel JA, Schmidt G, Moessner C, Schwaninger M, Marti R.

Chimia (Aarau). 2016 Sep;70(9):634. No abstract available.

PMID:
27931356
27.

Targeted delivery of glucocorticoids to macrophages in a mouse model of multiple sclerosis using inorganic-organic hybrid nanoparticles.

Montes-Cobos E, Ring S, Fischer HJ, Heck J, Strauß J, Schwaninger M, Reichardt SD, Feldmann C, Lühder F, Reichardt HM.

J Control Release. 2017 Jan 10;245:157-169. doi: 10.1016/j.jconrel.2016.12.003. Epub 2016 Dec 3.

PMID:
27919626
28.

Hyperglycemia in Stroke Impairs Polarization of Monocytes/Macrophages to a Protective Noninflammatory Cell Type.

Khan MA, Schultz S, Othman A, Fleming T, Lebrón-Galán R, Rades D, Clemente D, Nawroth PP, Schwaninger M.

J Neurosci. 2016 Sep 7;36(36):9313-25. doi: 10.1523/JNEUROSCI.0473-16.2016.

29.

Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity.

Jais A, Solas M, Backes H, Chaurasia B, Kleinridders A, Theurich S, Mauer J, Steculorum SM, Hampel B, Goldau J, Alber J, Förster CY, Eming SA, Schwaninger M, Ferrara N, Karsenty G, Brüning JC.

Cell. 2016 Aug 25;166(5):1338-1340. doi: 10.1016/j.cell.2016.08.010. No abstract available.

30.

Daring the Challenge and Thinking Big: The Value of Early Process R&D.

Abele S, Funel JA, Schmidt G, Moessner C, Schwaninger M, Marti R.

Chimia (Aarau). 2016;70(7-8):502-11. doi: 10.2533/chimia.2016.502. Erratum in: Chimia (Aarau). 2016 Sep;70(9):634.

PMID:
27561612
31.

Increased Plasma Matrix Metalloproteinase-9 Levels Contribute to Intracerebral Hemorrhage during Thrombolysis after Concomitant Stroke and Influenza Infection.

Muhammad S, Planz O, Schwaninger M.

Cerebrovasc Dis Extra. 2016;6(2):50-9. doi: 10.1159/000447750. Epub 2016 Aug 25.

32.

Uncoupling protein 2 protects mice from aging.

Hirose M, Schilf P, Lange F, Mayer J, Reichart G, Maity P, Jöhren O, Schwaninger M, Scharffetter-Kochanek K, Sina C, Sadik CD, Köhling R, Miroux B, Ibrahim SM.

Mitochondrion. 2016 Sep;30:42-50. doi: 10.1016/j.mito.2016.06.004. Epub 2016 Jun 27.

PMID:
27364833
33.

A brain microvasculature endothelial cell-specific viral vector with the potential to treat neurovascular and neurological diseases.

Körbelin J, Dogbevia G, Michelfelder S, Ridder DA, Hunger A, Wenzel J, Seismann H, Lampe M, Bannach J, Pasparakis M, Kleinschmidt JA, Schwaninger M, Trepel M.

EMBO Mol Med. 2016 Jun 1;8(6):609-25. doi: 10.15252/emmm.201506078. Print 2016 Jun.

34.

Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity.

Jais A, Solas M, Backes H, Chaurasia B, Kleinridders A, Theurich S, Mauer J, Steculorum SM, Hampel B, Goldau J, Alber J, Förster CY, Eming SA, Schwaninger M, Ferrara N, Karsenty G, Brüning JC.

Cell. 2016 May 5;165(4):882-95. doi: 10.1016/j.cell.2016.03.033. Epub 2016 Apr 28. Erratum in: Cell. 2016 Aug 25;166(5):1338-1340.

35.

Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive Impairment.

Blank T, Detje CN, Spieß A, Hagemeyer N, Brendecke SM, Wolfart J, Staszewski O, Zöller T, Papageorgiou I, Schneider J, Paricio-Montesinos R, Eisel UL, Manahan-Vaughan D, Jansen S, Lienenklaus S, Lu B, Imai Y, Müller M, Goelz SE, Baker DP, Schwaninger M, Kann O, Heikenwalder M, Kalinke U, Prinz M.

Immunity. 2016 Apr 19;44(4):901-12. doi: 10.1016/j.immuni.2016.04.005.

36.

The role of TWEAK/Fn14 signaling in the MPTP-model of Parkinson's disease.

Mustafa S, Martin HL, Burkly L, Costa A, Martins ML, Schwaninger M, Teismann P.

Neuroscience. 2016 Apr 5;319:116-22. doi: 10.1016/j.neuroscience.2016.01.034. Epub 2016 Jan 22.

37.

Neuroinflammation: A common denominator for stroke, multiple sclerosis and Alzheimer's disease.

Vries HE, Schwaninger M.

Biochim Biophys Acta. 2016 Mar;1862(3):297-8. doi: 10.1016/j.bbadis.2015.12.024. Epub 2015 Dec 31. No abstract available.

38.

Prostaglandin-dependent modulation of dopaminergic neurotransmission elicits inflammation-induced aversion in mice.

Fritz M, Klawonn AM, Nilsson A, Singh AK, Zajdel J, Wilhelms DB, Lazarus M, Löfberg A, Jaarola M, Kugelberg UÖ, Billiar TR, Hackam DJ, Sodhi CP, Breyer MD, Jakobsson J, Schwaninger M, Schütz G, Parkitna JR, Saper CB, Blomqvist A, Engblom D.

J Clin Invest. 2016 Feb;126(2):695-705.

39.

Apicobasal polarity of brain endothelial cells.

Worzfeld T, Schwaninger M.

J Cereb Blood Flow Metab. 2016 Feb;36(2):340-62. doi: 10.1177/0271678X15608644. Epub 2015 Oct 6. Review.

40.

A cross-laboratory preclinical study on the effectiveness of interleukin-1 receptor antagonist in stroke.

Maysami S, Wong R, Pradillo JM, Denes A, Dhungana H, Malm T, Koistinaho J, Orset C, Rahman M, Rubio M, Schwaninger M, Vivien D, Bath PM, Rothwell NJ, Allan SM.

J Cereb Blood Flow Metab. 2016 Mar;36(3):596-605. doi: 10.1177/0271678X15606714. Epub 2015 Sep 30.

41.

Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier.

Storck SE, Meister S, Nahrath J, Meißner JN, Schubert N, Di Spiezio A, Baches S, Vandenbroucke RE, Bouter Y, Prikulis I, Korth C, Weggen S, Heimann A, Schwaninger M, Bayer TA, Pietrzik CU.

J Clin Invest. 2016 Jan;126(1):123-36. doi: 10.1172/JCI81108. Epub 2015 Nov 30.

42.

Protective features of peripheral monocytes/macrophages in stroke.

Gliem M, Schwaninger M, Jander S.

Biochim Biophys Acta. 2016 Mar;1862(3):329-38. doi: 10.1016/j.bbadis.2015.11.004. Epub 2015 Nov 12. Review.

43.

Immune cell trafficking across the barriers of the central nervous system in multiple sclerosis and stroke.

Lopes Pinheiro MA, Kooij G, Mizee MR, Kamermans A, Enzmann G, Lyck R, Schwaninger M, Engelhardt B, de Vries HE.

Biochim Biophys Acta. 2016 Mar;1862(3):461-71. doi: 10.1016/j.bbadis.2015.10.018. Epub 2015 Oct 23. Review.

44.

Genetic manipulation of brain endothelial cells in vivo.

Assmann JC, Körbelin J, Schwaninger M.

Biochim Biophys Acta. 2016 Mar;1862(3):381-94. doi: 10.1016/j.bbadis.2015.10.006. Epub 2015 Oct 8. Review. No abstract available.

45.

Brain endothelial TAK1 and NEMO safeguard the neurovascular unit.

Ridder DA, Wenzel J, Müller K, Töllner K, Tong XK, Assmann JC, Stroobants S, Weber T, Niturad C, Fischer L, Lembrich B, Wolburg H, Grand'Maison M, Papadopoulos P, Korpos E, Truchetet F, Rades D, Sorokin LM, Schmidt-Supprian M, Bedell BJ, Pasparakis M, Balschun D, D'Hooge R, Löscher W, Hamel E, Schwaninger M.

J Exp Med. 2015 Sep 21;212(10):1529-49. doi: 10.1084/jem.20150165. Epub 2015 Sep 7.

46.

Nutritional or pharmacological activation of HCA(2) ameliorates neuroinflammation.

Offermanns S, Schwaninger M.

Trends Mol Med. 2015 Apr;21(4):245-55. doi: 10.1016/j.molmed.2015.02.002. Epub 2015 Mar 9. Review.

PMID:
25766751
47.

Immune-induced fever is mediated by IL-6 receptors on brain endothelial cells coupled to STAT3-dependent induction of brain endothelial prostaglandin synthesis.

Eskilsson A, Mirrasekhian E, Dufour S, Schwaninger M, Engblom D, Blomqvist A.

J Neurosci. 2014 Nov 26;34(48):15957-61. doi: 10.1523/JNEUROSCI.3520-14.2014.

48.

[Fumaric acid or dimethyl fumarate?].

Schwaninger M.

Nervenarzt. 2015 Jun;86(6):757. doi: 10.1007/s00115-014-4203-7. German. No abstract available.

PMID:
25374116
49.

Serum protein S100β is a diagnostic biomarker for distinguishing posterior circulation stroke from vertigo of nonvascular causes.

Purrucker JC, Herrmann O, Lutsch JK, Zorn M, Schwaninger M, Bruckner T, Auffarth GU, Veltkamp R.

Eur Neurol. 2014;72(5-6):278-84. doi: 10.1159/000363569. Epub 2014 Oct 16.

PMID:
25323105
50.

Deletion of prostaglandin E2 synthesizing enzymes in brain endothelial cells attenuates inflammatory fever.

Wilhelms DB, Kirilov M, Mirrasekhian E, Eskilsson A, Kugelberg UÖ, Klar C, Ridder DA, Herschman HR, Schwaninger M, Blomqvist A, Engblom D.

J Neurosci. 2014 Aug 27;34(35):11684-90. doi: 10.1523/JNEUROSCI.1838-14.2014.

Supplemental Content

Loading ...
Support Center