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Items: 1 to 50 of 68

1.

Mass Spectrometry-Based Tissue Imaging: The Next Frontier in Clinical Diagnostics?

Leung F, Eberlin LS, Schwamborn K, Heeren RMA, Winograd N, Cooks RG.

Clin Chem. 2019 Feb 8. pii: clinchem.2018.289694. doi: 10.1373/clinchem.2018.289694. [Epub ahead of print] No abstract available.

PMID:
30737204
2.

Proteomics in Pathology: The Special Issue.

Longuespée R, Casadonte R, Schwamborn K, Kriegsmann M.

Proteomics Clin Appl. 2019 Jan;13(1):e1800167. doi: 10.1002/prca.201800167. No abstract available.

PMID:
30730117
3.

Identification of MALDI Imaging Proteolytic Peptides Using LC-MS/MS-Based Biomarker Discovery Data: A Proof of Concept.

Longuespée R, Ly A, Casadonte R, Schwamborn K, Kazdal D, Zgorzelski C, Bollwein C, Kriegsmann K, Weichert W, Kriegsmann J, Schirmacher P, Fresnais M, Oliveira C, Kriegsmann M.

Proteomics Clin Appl. 2019 Jan;13(1):e1800158. doi: 10.1002/prca.201800158. Epub 2018 Dec 19.

PMID:
30525291
4.

Site-to-Site Reproducibility and Spatial Resolution in MALDI-MSI of Peptides from Formalin-Fixed Paraffin-Embedded Samples.

Ly A, Longuespée R, Casadonte R, Wandernoth P, Schwamborn K, Bollwein C, Marsching C, Kriegsmann K, Hopf C, Weichert W, Kriegsmann J, Schirmacher P, Kriegsmann M, Deininger SO.

Proteomics Clin Appl. 2019 Jan;13(1):e1800029. doi: 10.1002/prca.201800029. Epub 2019 Jan 4.

PMID:
30408343
5.

Discerning the Primary Carcinoma in Malignant Peritoneal and Pleural Effusions Using Imaging Mass Spectrometry-A Feasibility Study.

Schwamborn K, Weirich G, Steiger K, Zimmermann G, Schmidmayr M, Weichert W, Caprioli RM.

Proteomics Clin Appl. 2019 Jan;13(1):e1800064. doi: 10.1002/prca.201800064. Epub 2018 Oct 29.

PMID:
30311431
6.

Extracellular Matrix Imaging of Breast Tissue Pathologies by MALDI-Imaging Mass Spectrometry.

Angel PM, Schwamborn K, Comte-Walters S, Clift CL, Ball LE, Mehta AS, Drake RR.

Proteomics Clin Appl. 2019 Jan;13(1):e1700152. doi: 10.1002/prca.201700152. Epub 2018 Dec 14.

PMID:
30251340
7.

Digital PCR After MALDI-Mass Spectrometry Imaging to Combine Proteomic Mapping and Identification of Activating Mutations in Pulmonary Adenocarcinoma.

Kazdal D, Longuespée R, Dietz S, Casadonte R, Schwamborn K, Volckmar AL, Kriegsmann J, Kriegsmann K, Fresnais M, Stenzinger A, Sültmann H, Warth A, Kriegsmann M.

Proteomics Clin Appl. 2019 Jan;13(1):e1800034. doi: 10.1002/prca.201800034. Epub 2018 Oct 15.

PMID:
30216696
8.

In MALDI-Mass Spectrometry Imaging on Formalin-Fixed Paraffin-Embedded Tissue Specimen Section Thickness Significantly Influences m/z Peak Intensity.

Longuespée R, Kriegsmann K, Cremer M, Zgorzelski C, Casadonte R, Kazdal D, Kriegsmann J, Weichert W, Schwamborn K, Fresnais M, Schirmacher P, Kriegsmann M.

Proteomics Clin Appl. 2019 Jan;13(1):e1800074. doi: 10.1002/prca.201800074. Epub 2018 Oct 1.

PMID:
30216687
9.

Mass Spectrometry Imaging and Integration with Other Imaging Modalities for Greater Molecular Understanding of Biological Tissues.

Porta Siegel T, Hamm G, Bunch J, Cappell J, Fletcher JS, Schwamborn K.

Mol Imaging Biol. 2018 Dec;20(6):888-901. doi: 10.1007/s11307-018-1267-y. Review.

10.

Process intensification of EB66® cell cultivations leads to high-yield yellow fever and Zika virus production.

Nikolay A, Léon A, Schwamborn K, Genzel Y, Reichl U.

Appl Microbiol Biotechnol. 2018 Oct;102(20):8725-8737. doi: 10.1007/s00253-018-9275-z. Epub 2018 Aug 8.

11.

Combined Immunohistochemistry after Mass Spectrometry Imaging for Superior Spatial Information.

Kriegsmann K, Longuespée R, Hundemer M, Zgorzelski C, Casadonte R, Schwamborn K, Weichert W, Schirmacher P, Harms A, Kazdal D, Leichsenring J, Stenzinger A, Warth A, Fresnais M, Kriegsmann J, Kriegsmann M.

Proteomics Clin Appl. 2019 Jan;13(1):e1800035. doi: 10.1002/prca.201800035. Epub 2018 Aug 21.

PMID:
30035857
12.

[Histopathological research laboratories in translational research : Conception and integration into the infrastructure of pathological institutes].

Steiger K, Ballke S, Yen HY, Seelbach O, Alkhamas A, Boxberg M, Schwamborn K, Knolle PA, Weichert W, Mogler C.

Pathologe. 2018 Jul 19. doi: 10.1007/s00292-018-0458-2. [Epub ahead of print] German.

PMID:
30027333
13.

Back to the future - Is the drug repositioning concept applicable to vaccines?

Schwamborn K.

Vaccine. 2018 May 11;36(20):2743-2744. doi: 10.1016/j.vaccine.2018.04.020. Epub 2018 Apr 13. No abstract available.

14.

99mTechnetium-based Prostate-specific Membrane Antigen-radioguided Surgery in Recurrent Prostate Cancer.

Maurer T, Robu S, Schottelius M, Schwamborn K, Rauscher I, van den Berg NS, van Leeuwen FWB, Haller B, Horn T, Heck MM, Gschwend JE, Schwaiger M, Wester HJ, Eiber M.

Eur Urol. 2018 Apr 3. pii: S0302-2838(18)30189-1. doi: 10.1016/j.eururo.2018.03.013. [Epub ahead of print]

PMID:
29625755
15.

Radio-guided-surgery of a paravertebral paraganglioma using I-123-MIBG.

Rischpler C, Schwamborn K, Schwaiger M, Maurer T.

Nuklearmedizin. 2018 Feb;57(1):N2-N3. doi: 10.1055/s-0038-1636982. Epub 2018 Feb 21. No abstract available.

PMID:
29536488
16.

Proteomics in Pathology.

Longuespée R, Casadonte R, Schwamborn K, Reuss D, Kazdal D, Kriegsmann K, von Deimling A, Weichert W, Schirmacher P, Kriegsmann J, Kriegsmann M.

Proteomics. 2018 Jan;18(2). doi: 10.1002/pmic.201700361.

PMID:
29236356
17.

Investigating the influence of standard staining procedures on the copper distribution and concentration in Wilson's disease liver samples by laser ablation-inductively coupled plasma-mass spectrometry.

Hachmöller O, Aichler M, Schwamborn K, Lutz L, Werner M, Sperling M, Walch A, Karst U.

J Trace Elem Med Biol. 2017 Dec;44:71-75. doi: 10.1016/j.jtemb.2017.06.002. Epub 2017 Jun 15.

PMID:
28965603
18.

Interlaboratory concordance of PD-L1 immunohistochemistry for non-small-cell lung cancer.

Scheel AH, Baenfer G, Baretton G, Dietel M, Diezko R, Henkel T, Heukamp LC, Jasani B, Jöhrens K, Kirchner T, Lasitschka F, Petersen I, Reu S, Schildhaus HU, Schirmacher P, Schwamborn K, Sommer U, Stoss O, Tiemann M, Warth A, Weichert W, Wolf J, Büttner R, Rüschoff J.

Histopathology. 2018 Feb;72(3):449-459. doi: 10.1111/his.13375. Epub 2017 Nov 21.

PMID:
28851100
19.

Prognostic Impact of a 12-gene Progression Score in Non-muscle-invasive Bladder Cancer: A Prospective Multicentre Validation Study.

Dyrskjøt L, Reinert T, Algaba F, Christensen E, Nieboer D, Hermann GG, Mogensen K, Beukers W, Marquez M, Segersten U, Høyer S, Ulhøi BP, Hartmann A, Stöhr R, Wach S, Nawroth R, Schwamborn K, Tulic C, Simic T, Junker K, Harving N, Petersen AC, Jensen JB, Keck B, Grimm MO, Horstmann M, Maurer T, Steyerberg EW, Zwarthoff EC, Real FX, Malats N, Malmström PU, Ørntoft TF.

Eur Urol. 2017 Sep;72(3):461-469. doi: 10.1016/j.eururo.2017.05.040. Epub 2017 Jun 2.

PMID:
28583312
20.

The Importance of Histology and Pathology in Mass Spectrometry Imaging.

Schwamborn K.

Adv Cancer Res. 2017;134:1-26. doi: 10.1016/bs.acr.2016.11.001. Epub 2016 Dec 21. Review.

PMID:
28110647
21.

The EB66® cell line as a valuable cell substrate for MVA-based vaccines production.

Léon A, David AL, Madeline B, Guianvarc'h L, Dureau E, Champion-Arnaud P, Hebben M, Huss T, Chatrenet B, Schwamborn K.

Vaccine. 2016 Nov 21;34(48):5878-5885. doi: 10.1016/j.vaccine.2016.10.043. Epub 2016 Oct 27.

22.

Value of 111 In-prostate-specific membrane antigen (PSMA)-radioguided surgery for salvage lymphadenectomy in recurrent prostate cancer: correlation with histopathology and clinical follow-up.

Rauscher I, Düwel C, Wirtz M, Schottelius M, Wester HJ, Schwamborn K, Haller B, Schwaiger M, Gschwend JE, Eiber M, Maurer T.

BJU Int. 2017 Jul;120(1):40-47. doi: 10.1111/bju.13713. Epub 2016 Dec 4.

23.

MALDI imaging mass spectrometry - From bench to bedside.

Schwamborn K, Kriegsmann M, Weichert W.

Biochim Biophys Acta Proteins Proteom. 2017 Jul;1865(7):776-783. doi: 10.1016/j.bbapap.2016.10.014. Epub 2016 Oct 31. Review.

PMID:
27810414
24.

Targeted vaccination against the bevacizumab binding site on VEGF using 3D-structured peptides elicits efficient antitumor activity.

Wentink MQ, Hackeng TM, Tabruyn SP, Puijk WC, Schwamborn K, Altschuh D, Meloen RH, Schuurman T, Griffioen AW, Timmerman P.

Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12532-12537. Epub 2016 Oct 17.

25.

Reliable Entity Subtyping in Non-small Cell Lung Cancer by Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry on Formalin-fixed Paraffin-embedded Tissue Specimens.

Kriegsmann M, Casadonte R, Kriegsmann J, Dienemann H, Schirmacher P, Hendrik Kobarg J, Schwamborn K, Stenzinger A, Warth A, Weichert W.

Mol Cell Proteomics. 2016 Oct;15(10):3081-3089. Epub 2016 Jul 29.

26.

PSMA Theranostics Using PET and Subsequent Radioguided Surgery in Recurrent Prostate Cancer.

Maurer T, Schwamborn K, Schottelius M, Wester HJ, Schwaiger M, Gschwend JE, Eiber M.

Clin Genitourin Cancer. 2016 Oct;14(5):e549-e552. doi: 10.1016/j.clgc.2016.05.020. Epub 2016 May 27. No abstract available.

PMID:
27318956
27.

Element bioimaging of liver needle biopsy specimens from patients with Wilson's disease by laser ablation-inductively coupled plasma-mass spectrometry.

Hachmöller O, Aichler M, Schwamborn K, Lutz L, Werner M, Sperling M, Walch A, Karst U.

J Trace Elem Med Biol. 2016 May;35:97-102. doi: 10.1016/j.jtemb.2016.02.001. Epub 2016 Feb 10.

PMID:
27049132
28.

Elemental bioimaging and speciation analysis for the investigation of Wilson's disease using μXRF and XANES.

Hachmöller O, Buzanich AG, Aichler M, Radtke M, Dietrich D, Schwamborn K, Lutz L, Werner M, Sperling M, Walch A, Karst U.

Metallomics. 2016 Jul 13;8(7):648-53. doi: 10.1039/c6mt00001k.

PMID:
26999628
29.

Histone acetylation and histone acetyltransferases show significant alterations in human abdominal aortic aneurysm.

Han Y, Tanios F, Reeps C, Zhang J, Schwamborn K, Eckstein HH, Zernecke A, Pelisek J.

Clin Epigenetics. 2016 Jan 13;8:3. doi: 10.1186/s13148-016-0169-6. eCollection 2016.

30.

68Ga-PSMA-HBED-CC PET for Differential Diagnosis of Suggestive Lung Lesions in Patients with Prostate Cancer.

Pyka T, Weirich G, Einspieler I, Maurer T, Theisen J, Hatzichristodoulou G, Schwamborn K, Schwaiger M, Eiber M.

J Nucl Med. 2016 Mar;57(3):367-71. doi: 10.2967/jnumed.115.164442. Epub 2015 Nov 19.

31.

Differential diagnosis of bladder versus colorectal adenocarcinoma: keratin 7 and GATA3 positivity in nuclear ß-catenin-negative glandular tumours defines adenocarcinoma of the bladder.

Broede A, Oll M, Maurer A, Siegert S, Stoerkel S, Golz R, Schwamborn K, Veeck J, Knuechel R, Gaisa NT; German study group of bladder cancers.

J Clin Pathol. 2016 Apr;69(4):307-12. doi: 10.1136/jclinpath-2015-203144. Epub 2015 Oct 13.

PMID:
26463756
32.

CXCR4: A Potential Marker for Inflammatory Activity in Abdominal Aortic Aneurysm Wall.

Tanios F, Pelisek J, Lutz B, Reutersberg B, Matevossian E, Schwamborn K, Hösel V, Eckstein HH, Reeps C.

Eur J Vasc Endovasc Surg. 2015 Dec;50(6):745-53. doi: 10.1016/j.ejvs.2015.07.040. Epub 2015 Sep 4.

33.

Cell substrates for the production of viral vaccines.

Aubrit F, Perugi F, Léon A, Guéhenneux F, Champion-Arnaud P, Lahmar M, Schwamborn K.

Vaccine. 2015 Nov 4;33(44):5905-12. doi: 10.1016/j.vaccine.2015.06.110. Epub 2015 Jul 15. Review.

PMID:
26187258
34.

In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma.

Philipp-Abbrederis K, Herrmann K, Knop S, Schottelius M, Eiber M, Lückerath K, Pietschmann E, Habringer S, Gerngroß C, Franke K, Rudelius M, Schirbel A, Lapa C, Schwamborn K, Steidle S, Hartmann E, Rosenwald A, Kropf S, Beer AJ, Peschel C, Einsele H, Buck AK, Schwaiger M, Götze K, Wester HJ, Keller U.

EMBO Mol Med. 2015 Apr;7(4):477-87. doi: 10.15252/emmm.201404698.

35.

A combination of in vitro techniques for efficient discovery of functional monoclonal antibodies against human CXC chemokine receptor-2 (CXCR2).

Boshuizen RS, Marsden C, Turkstra J, Rossant CJ, Slootstra J, Copley C, Schwamborn K.

MAbs. 2014;6(6):1415-24. doi: 10.4161/mabs.36237.

36.

Opposing role of Notch1 and Notch2 in a Kras(G12D)-driven murine non-small cell lung cancer model.

Baumgart A, Mazur PK, Anton M, Rudelius M, Schwamborn K, Feuchtinger A, Behnke K, Walch A, Braren R, Peschel C, Duyster J, Siveke JT, Dechow T.

Oncogene. 2015 Jan 29;34(5):578-88. doi: 10.1038/onc.2013.592. Epub 2014 Feb 10.

PMID:
24509876
37.

Imaging mass spectrometry in biomarker discovery and validation.

Schwamborn K.

J Proteomics. 2012 Aug 30;75(16):4990-8. doi: 10.1016/j.jprot.2012.06.015. Epub 2012 Jun 27. Review.

PMID:
22749859
38.

MALDI MS imaging as a powerful tool for investigating synovial tissue.

Kriegsmann M, Seeley EH, Schwarting A, Kriegsmann J, Otto M, Thabe H, Dierkes B, Biehl C, Sack U, Wellmann A, Kahaly GJ, Schwamborn K, Caprioli RM.

Scand J Rheumatol. 2012 Aug;41(4):305-9. doi: 10.3109/03009742.2011.647925. Epub 2012 May 29.

39.

Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled.

Tauriello DV, Jordens I, Kirchner K, Slootstra JW, Kruitwagen T, Bouwman BA, Noutsou M, Rüdiger SG, Schwamborn K, Schambony A, Maurice MM.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):E812-20. doi: 10.1073/pnas.1114802109. Epub 2012 Mar 12.

40.

Proteomic tissue profiling for the improvement of grading of noninvasive papillary urothelial neoplasia.

Oezdemir RF, Gaisa NT, Lindemann-Docter K, Gostek S, Weiskirchen R, Ahrens M, Schwamborn K, Stephan C, Pfister D, Heidenreich A, Knuechel R, Henkel C.

Clin Biochem. 2012 Jan;45(1-2):7-11. doi: 10.1016/j.clinbiochem.2011.09.013. Epub 2011 Oct 2. Erratum in: Clin Biochem. 2012 Nov;45(16-17):1539.

PMID:
21986590
41.

Efficacy of dose-reduced lenalidomide in patients with refractory or recurrent multiple myeloma.

Schwamborn K, Gorschlüter M, Glasmacher A, Schmidt-Wolf IG; German Refractory Myeloma Study Group.

Ger Med Sci. 2011;9:Doc26. doi: 10.3205/000149. Epub 2011 Sep 27.

42.

Imaging of intact tissue sections: moving beyond the microscope.

Seeley EH, Schwamborn K, Caprioli RM.

J Biol Chem. 2011 Jul 22;286(29):25459-66. doi: 10.1074/jbc.R111.225854. Epub 2011 Jun 1. Review.

43.

From proteomic multimarker profiling to interesting proteins: thymosin-β(4) and kininogen-1 as new potential biomarkers for inflammatory hepatic lesions.

Henkel C, Schwamborn K, Zimmermann HW, Tacke F, Kühnen E, Odenthal M, Groseclose MR, Caprioli RM, Weiskirchen R.

J Cell Mol Med. 2011 Oct;15(10):2176-88. doi: 10.1111/j.1582-4934.2010.01204.x.

44.

MALDI imaging as a specific diagnostic tool for routine cervical cytology specimens.

Schwamborn K, Krieg RC, Uhlig S, Ikenberg H, Wellmann A.

Int J Mol Med. 2011 Mar;27(3):417-21. doi: 10.3892/ijmm.2010.587. Epub 2010 Dec 21.

PMID:
21174066
45.

Tissue and serum proteomic profiling for diagnostic and prognostic bladder cancer biomarkers.

Schwamborn K, Gaisa NT, Henkel C.

Expert Rev Proteomics. 2010 Dec;7(6):897-906. doi: 10.1586/epr.10.82. Review.

PMID:
21142890
46.

MALDI imaging mass spectrometry--painting molecular pictures.

Schwamborn K, Caprioli RM.

Mol Oncol. 2010 Dec;4(6):529-38. doi: 10.1016/j.molonc.2010.09.002. Epub 2010 Sep 25. Review.

47.

Application of MALDI imaging for the diagnosis of classical Hodgkin lymphoma.

Schwamborn K, Krieg RC, Jirak P, Ott G, Knüchel R, Rosenwald A, Wellmann A.

J Cancer Res Clin Oncol. 2010 Nov;136(11):1651-5. doi: 10.1007/s00432-010-0823-x. Epub 2010 Feb 21.

PMID:
20865362
48.

Molecular imaging by mass spectrometry--looking beyond classical histology.

Schwamborn K, Caprioli RM.

Nat Rev Cancer. 2010 Sep;10(9):639-46. doi: 10.1038/nrc2917. Epub 2010 Aug 19. Review.

PMID:
20720571
49.

[Current knowledge in molecular pathology of urothelial cancer].

Knüchel-Clarke R, Dahl E, Gaisa NT, Schwamborn K, Lindemann-Docter K, Henkel C.

Pathologe. 2010 Oct;31 Suppl 2:234-8. doi: 10.1007/s00292-010-1324-z. Review. German.

PMID:
20665023
50.

PARP-1 transcriptional activity is regulated by sumoylation upon heat shock.

Martin N, Schwamborn K, Schreiber V, Werner A, Guillier C, Zhang XD, Bischof O, Seeler JS, Dejean A.

EMBO J. 2009 Nov 18;28(22):3534-48. doi: 10.1038/emboj.2009.279. Epub 2009 Sep 24.

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