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Items: 31

1.

A modular transcriptome map of mature B cell lymphomas.

Loeffler-Wirth H, Kreuz M, Hopp L, Arakelyan A, Haake A, Cogliatti SB, Feller AC, Hansmann ML, Lenze D, Möller P, Müller-Hermelink HK, Fortenbacher E, Willscher E, Ott G, Rosenwald A, Pott C, Schwaenen C, Trautmann H, Wessendorf S, Stein H, Szczepanowski M, Trümper L, Hummel M, Klapper W, Siebert R, Loeffler M, Binder H; German Cancer Aid consortium Molecular Mechanisms for Malignant Lymphoma.

Genome Med. 2019 Apr 30;11(1):27. doi: 10.1186/s13073-019-0637-7.

2.

A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma.

Salaverria I, Martin-Guerrero I, Wagener R, Kreuz M, Kohler CW, Richter J, Pienkowska-Grela B, Adam P, Burkhardt B, Claviez A, Damm-Welk C, Drexler HG, Hummel M, Jaffe ES, Küppers R, Lefebvre C, Lisfeld J, Löffler M, Macleod RA, Nagel I, Oschlies I, Rosolowski M, Russell RB, Rymkiewicz G, Schindler D, Schlesner M, Scholtysik R, Schwaenen C, Spang R, Szczepanowski M, Trümper L, Vater I, Wessendorf S, Klapper W, Siebert R; Molecular Mechanisms in Malignant Lymphoma Network Project; Berlin-Frankfurt-Münster Non-Hodgkin Lymphoma Group.

Blood. 2014 Feb 20;123(8):1187-98. doi: 10.1182/blood-2013-06-507996. Epub 2014 Jan 7.

3.

Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma.

Aukema SM, Kreuz M, Kohler CW, Rosolowski M, Hasenclever D, Hummel M, Küppers R, Lenze D, Ott G, Pott C, Richter J, Rosenwald A, Szczepanowski M, Schwaenen C, Stein H, Trautmann H, Wessendorf S, Trümper L, Loeffler M, Spang R, Kluin PM, Klapper W, Siebert R; Molecular Mechanisms in Malignant Lymphomas Network Project.

Haematologica. 2014 Apr;99(4):726-35. doi: 10.3324/haematol.2013.091827. Epub 2013 Oct 31.

4.

High resolution copy number analysis of IRF4 translocation-positive diffuse large B-cell and follicular lymphomas.

Salaverria I, Martin-Guerrero I, Burkhardt B, Kreuz M, Zenz T, Oschlies I, Arnold N, Baudis M, Bens S, García-Orad A, Lisfeld J, Schwaenen C, Szczepanowski M, Wessendorf S, Pfreundschuh M, Trümper L, Klapper W, Siebert R.

Genes Chromosomes Cancer. 2013 Feb;52(2):150-5. doi: 10.1002/gcc.22014. Epub 2012 Oct 17.

PMID:
23073988
5.

Recurrent deletions of the TNFSF7 and TNFSF9 genes in 19p13.3 in diffuse large B-cell and Burkitt lymphomas.

Scholtysik R, Nagel I, Kreuz M, Vater I, Giefing M, Schwaenen C, Wessendorf S, Trümper L, Loeffler M, Siebert R, Küppers R.

Int J Cancer. 2012 Sep 1;131(5):E830-5. doi: 10.1002/ijc.27416. Epub 2012 Jan 31.

6.

Identification of genomic alterations associated with metastasis and cancer specific survival in clear cell renal cell carcinoma.

Sanjmyatav J, Junker K, Matthes S, Muehr M, Sava D, Sternal M, Wessendorf S, Kreuz M, Gajda M, Wunderlich H, Schwaenen C.

J Urol. 2011 Nov;186(5):2078-83. doi: 10.1016/j.juro.2011.06.050. Epub 2011 Sep 23.

PMID:
21944119
7.

Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults.

Salaverria I, Philipp C, Oschlies I, Kohler CW, Kreuz M, Szczepanowski M, Burkhardt B, Trautmann H, Gesk S, Andrusiewicz M, Berger H, Fey M, Harder L, Hasenclever D, Hummel M, Loeffler M, Mahn F, Martin-Guerrero I, Pellissery S, Pott C, Pfreundschuh M, Reiter A, Richter J, Rosolowski M, Schwaenen C, Stein H, Trümper L, Wessendorf S, Spang R, Küppers R, Klapper W, Siebert R; Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe; German High-Grade Lymphoma Study Group; Berlin-Frankfurt-Münster-NHL trial group.

Blood. 2011 Jul 7;118(1):139-47. doi: 10.1182/blood-2011-01-330795. Epub 2011 Apr 12.

PMID:
21487109
8.

Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis.

Scholtysik R, Kreuz M, Klapper W, Burkhardt B, Feller AC, Hummel M, Loeffler M, Rosolowski M, Schwaenen C, Spang R, Stein H, Thorns C, Trümper L, Vater I, Wessendorf S, Zenz T, Siebert R, Küppers R; Molecular Mechanisms in Malignant Lymphomas Network Project of Deutsche Krebshilfe.

Haematologica. 2010 Dec;95(12):2047-55. doi: 10.3324/haematol.2010.026831. Epub 2010 Sep 7.

9.

New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling.

Martín-Subero JI, Kreuz M, Bibikova M, Bentink S, Ammerpohl O, Wickham-Garcia E, Rosolowski M, Richter J, Lopez-Serra L, Ballestar E, Berger H, Agirre X, Bernd HW, Calvanese V, Cogliatti SB, Drexler HG, Fan JB, Fraga MF, Hansmann ML, Hummel M, Klapper W, Korn B, Küppers R, Macleod RA, Möller P, Ott G, Pott C, Prosper F, Rosenwald A, Schwaenen C, Schübeler D, Seifert M, Stürzenhofecker B, Weber M, Wessendorf S, Loeffler M, Trümper L, Stein H, Spang R, Esteller M, Barker D, Hasenclever D, Siebert R; Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe.

Blood. 2009 Mar 12;113(11):2488-97. doi: 10.1182/blood-2008-04-152900. Epub 2008 Dec 15.

PMID:
19075189
10.

Microarray-based genomic profiling reveals novel genomic aberrations in follicular lymphoma which associate with patient survival and gene expression status.

Schwaenen C, Viardot A, Berger H, Barth TF, Bentink S, Döhner H, Enz M, Feller AC, Hansmann ML, Hummel M, Kestler HA, Klapper W, Kreuz M, Lenze D, Loeffler M, Möller P, Müller-Hermelink HK, Ott G, Rosolowski M, Rosenwald A, Ruf S, Siebert R, Spang R, Stein H, Truemper L, Lichter P, Bentz M, Wessendorf S; Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe.

Genes Chromosomes Cancer. 2009 Jan;48(1):39-54. doi: 10.1002/gcc.20617.

PMID:
18828156
11.

Pathway activation patterns in diffuse large B-cell lymphomas.

Bentink S, Wessendorf S, Schwaenen C, Rosolowski M, Klapper W, Rosenwald A, Ott G, Banham AH, Berger H, Feller AC, Hansmann ML, Hasenclever D, Hummel M, Lenze D, Möller P, Stuerzenhofecker B, Loeffler M, Truemper L, Stein H, Siebert R, Spang R; Molecular Mechanisms in Malignant Lymphomas Network Project of the.

Leukemia. 2008 Sep;22(9):1746-54. doi: 10.1038/leu.2008.166. Epub 2008 Jun 26.

PMID:
18580954
12.

Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials.

Klapper W, Szczepanowski M, Burkhardt B, Berger H, Rosolowski M, Bentink S, Schwaenen C, Wessendorf S, Spang R, Möller P, Hansmann ML, Bernd HW, Ott G, Hummel M, Stein H, Loeffler M, Trümper L, Zimmermann M, Reiter A, Siebert R; Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe.

Blood. 2008 Aug 15;112(4):1374-81. doi: 10.1182/blood-2008-01-136465. Epub 2008 May 28.

PMID:
18509088
13.

Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma.

Dierlamm J, Murga Penas EM, Bentink S, Wessendorf S, Berger H, Hummel M, Klapper W, Lenze D, Rosenwald A, Haralambieva E, Ott G, Cogliatti SB, Möller P, Schwaenen C, Stein H, Löffler M, Spang R, Trümper L, Siebert R; Deutsche Krebshilfe Network Project "Molecular Mechanisms in Malignant Lymphomas".

Haematologica. 2008 May;93(5):688-96. doi: 10.3324/haematol.12057. Epub 2008 Mar 26.

14.

Development and implementation of an analysis tool for array-based comparative genomic hybridization.

Kreuz M, Rosolowski M, Berger H, Schwaenen C, Wessendorf S, Loeffler M, Hasenclever D.

Methods Inf Med. 2007;46(5):608-13.

PMID:
17938787
15.

Further delineation of chromosomal consensus regions in primary mediastinal B-cell lymphomas: an analysis of 37 tumor samples using high-resolution genomic profiling (array-CGH).

Wessendorf S, Barth TF, Viardot A, Mueller A, Kestler HA, Kohlhammer H, Lichter P, Bentz M, Döhner H, Möller P, Schwaenen C.

Leukemia. 2007 Dec;21(12):2463-9. Epub 2007 Aug 30.

PMID:
17728785
16.

Matrix-comparative genomic hybridization from multicenter formalin-fixed paraffin-embedded colorectal cancer tissue blocks.

Fensterer H, Radlwimmer B, Sträter J, Buchholz M, Aust DE, Julié C, Radvanyi F, Nordlinger B, Belluco C, Van Cutsem E, Köhne CH, Kestler HA, Schwaenen C, Nessling M, Lutz MP, Lichter P, Gress TM; EORTC Gastrointestinal (GI) Group.

BMC Cancer. 2007 Apr 2;7:58.

17.

[A new dimension of DNA analysis: genomic profiling by matrix CGH].

Joos S, Radlwimmer B, Nessling M, Fritz B, Schwaenen C, Wessendorf S, Bentz M, Lichter P.

Verh Dtsch Ges Pathol. 2003;87:165-71. German.

PMID:
16888909
18.

Disclosure of candidate genes in acute myeloid leukemia with complex karyotypes using microarray-based molecular characterization.

Rücker FG, Bullinger L, Schwaenen C, Lipka DB, Wessendorf S, Fröhling S, Bentz M, Miller S, Scholl C, Schlenk RF, Radlwimmer B, Kestler HA, Pollack JR, Lichter P, Döhner K, Döhner H.

J Clin Oncol. 2006 Aug 20;24(24):3887-94. Epub 2006 Jul 24.

PMID:
16864856
19.

Recurrent FGFR1 amplification and high FGFR1 protein expression in oral squamous cell carcinoma (OSCC).

Freier K, Schwaenen C, Sticht C, Flechtenmacher C, Mühling J, Hofele C, Radlwimmer B, Lichter P, Joos S.

Oral Oncol. 2007 Jan;43(1):60-6. Epub 2006 Jun 27.

PMID:
16807070
20.

A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling.

Hummel M, Bentink S, Berger H, Klapper W, Wessendorf S, Barth TF, Bernd HW, Cogliatti SB, Dierlamm J, Feller AC, Hansmann ML, Haralambieva E, Harder L, Hasenclever D, Kühn M, Lenze D, Lichter P, Martin-Subero JI, Möller P, Müller-Hermelink HK, Ott G, Parwaresch RM, Pott C, Rosenwald A, Rosolowski M, Schwaenen C, Stürzenhofecker B, Szczepanowski M, Trautmann H, Wacker HH, Spang R, Loeffler M, Trümper L, Stein H, Siebert R; Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe.

N Engl J Med. 2006 Jun 8;354(23):2419-30.

21.

Antagonizing inactivated tumor suppressor genes and activated oncogenes by a versatile transgenesis system: application in mantle cell lymphoma.

Pscherer A, Schliwka J, Wildenberger K, Mincheva A, Schwaenen C, Döhner H, Stilgenbauer S, Lichter P.

FASEB J. 2006 Jun;20(8):1188-90. Epub 2006 Apr 24.

PMID:
16636107
22.

Molecular classification of human gliomas using matrix-based comparative genomic hybridization.

Roerig P, Nessling M, Radlwimmer B, Joos S, Wrobel G, Schwaenen C, Reifenberger G, Lichter P.

Int J Cancer. 2005 Oct 20;117(1):95-103.

23.

Candidate genes in breast cancer revealed by microarray-based comparative genomic hybridization of archived tissue.

Nessling M, Richter K, Schwaenen C, Roerig P, Wrobel G, Wessendorf S, Fritz B, Bentz M, Sinn HP, Radlwimmer B, Lichter P.

Cancer Res. 2005 Jan 15;65(2):439-47.

24.

Genomic DNA-chip hybridization reveals a higher incidence of genomic amplifications in pancreatic cancer than conventional comparative genomic hybridization and leads to the identification of novel candidate genes.

Holzmann K, Kohlhammer H, Schwaenen C, Wessendorf S, Kestler HA, Schwoerer A, Rau B, Radlwimmer B, Döhner H, Lichter P, Gress T, Bentz M.

Cancer Res. 2004 Jul 1;64(13):4428-33. Erratum in: Cancer Res. 2004 Sep 1;64(17):6358.

25.

Overexpression of urokinase receptor and cell surface urokinase-type plasminogen activator in the human vessel wall with different types of atherosclerotic lesions.

Steins MB, Padró T, Schwaenen C, Ruiz S, Mesters RM, Berdel WE, Kienast J.

Blood Coagul Fibrinolysis. 2004 Jul;15(5):383-91.

PMID:
15205586
26.

Genomic DNA-chip hybridization in t(11;14)-positive mantle cell lymphomas shows a high frequency of aberrations and allows a refined characterization of consensus regions.

Kohlhammer H, Schwaenen C, Wessendorf S, Holzmann K, Kestler HA, Kienle D, Barth TF, Möller P, Ott G, Kalla J, Radlwimmer B, Pscherer A, Stilgenbauer S, Döhner H, Lichter P, Bentz M.

Blood. 2004 Aug 1;104(3):795-801. Epub 2004 Apr 13.

PMID:
15090459
27.

Automated array-based genomic profiling in chronic lymphocytic leukemia: development of a clinical tool and discovery of recurrent genomic alterations.

Schwaenen C, Nessling M, Wessendorf S, Salvi T, Wrobel G, Radlwimmer B, Kestler HA, Haslinger C, Stilgenbauer S, Döhner H, Bentz M, Lichter P.

Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):1039-44. Epub 2004 Jan 16.

28.

DNA microarray analysis in malignant lymphomas.

Schwaenen C, Wessendorf S, Kestler HA, Döhner H, Lichter P, Bentz M.

Ann Hematol. 2003 Jun;82(6):323-32. Epub 2003 Apr 26. Review.

PMID:
12719886
29.

Hidden gene amplifications in aggressive B-cell non-Hodgkin lymphomas detected by microarray-based comparative genomic hybridization.

Wessendorf S, Schwaenen C, Kohlhammer H, Kienle D, Wrobel G, Barth TF, Nessling M, Möller P, Döhner H, Lichter P, Bentz M.

Oncogene. 2003 Mar 6;22(9):1425-9.

PMID:
12618769
30.

Microarray-based copy number and expression profiling in dedifferentiated and pleomorphic liposarcoma.

Fritz B, Schubert F, Wrobel G, Schwaenen C, Wessendorf S, Nessling M, Korz C, Rieker RJ, Montgomery K, Kucherlapati R, Mechtersheimer G, Eils R, Joos S, Lichter P.

Cancer Res. 2002 Jun 1;62(11):2993-8.

31.

Automated screening for genomic imbalances using matrix-based comparative genomic hybridization.

Wessendorf S, Fritz B, Wrobel G, Nessling M, Lampel S, Göettel D, Küepper M, Joos S, Hopman T, Kokocinski F, Döhner H, Bentz M, Schwäenen C, Lichter P.

Lab Invest. 2002 Jan;82(1):47-60.

PMID:
11796825

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