Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 22

1.

A High-Throughput Assay for DNA Replication Inhibitors Based upon Multivariate Analysis of Yeast Growth Kinetics.

Ngo M, Wechter N, Tsai E, Shun TY, Gough A, Schurdak ME, Schwacha A, Vogt A.

SLAS Discov. 2019 Jul;24(6):669-681. doi: 10.1177/2472555219829740. Epub 2019 Feb 25.

PMID:
30802412
2.

A Checkpoint-Related Function of the MCM Replicative Helicase Is Required to Avert Accumulation of RNA:DNA Hybrids during S-phase and Ensuing DSBs during G2/M.

Vijayraghavan S, Tsai FL, Schwacha A.

PLoS Genet. 2016 Aug 24;12(8):e1006277. doi: 10.1371/journal.pgen.1006277. eCollection 2016 Aug.

3.

DNA replication: Strand separation unravelled.

Bochman ML, Schwacha A.

Nature. 2015 Aug 13;524(7564):166-7. doi: 10.1038/nature14643. Epub 2015 Jul 29. No abstract available.

PMID:
26222029
4.

Mcm2-7 Is an Active Player in the DNA Replication Checkpoint Signaling Cascade via Proposed Modulation of Its DNA Gate.

Tsai FL, Vijayraghavan S, Prinz J, MacAlpine HK, MacAlpine DM, Schwacha A.

Mol Cell Biol. 2015 Jun;35(12):2131-43. doi: 10.1128/MCB.01357-14. Epub 2015 Apr 13.

5.

The Mcm2-7 replicative helicase: a promising chemotherapeutic target.

Simon NE, Schwacha A.

Biomed Res Int. 2014;2014:549719. doi: 10.1155/2014/549719. Epub 2014 Aug 28. Review.

6.

Ciprofloxacin is an inhibitor of the Mcm2-7 replicative helicase.

Simon N, Bochman ML, Seguin S, Brodsky JL, Seibel WL, Schwacha A.

Biosci Rep. 2013 Oct 7;33(5). pii: e00072. doi: 10.1042/BSR20130083.

7.

The eukaryotic Mcm2-7 replicative helicase.

Vijayraghavan S, Schwacha A.

Subcell Biochem. 2012;62:113-34. doi: 10.1007/978-94-007-4572-8_7. Review.

PMID:
22918583
8.

The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'.

Bochman ML, Schwacha A.

Nucleic Acids Res. 2010 Oct;38(18):6078-88. doi: 10.1093/nar/gkq422. Epub 2010 May 19.

9.

The Mcm complex: unwinding the mechanism of a replicative helicase.

Bochman ML, Schwacha A.

Microbiol Mol Biol Rev. 2009 Dec;73(4):652-83. doi: 10.1128/MMBR.00019-09. Review.

10.

Subunit organization of Mcm2-7 and the unequal role of active sites in ATP hydrolysis and viability.

Bochman ML, Bell SP, Schwacha A.

Mol Cell Biol. 2008 Oct;28(19):5865-73. doi: 10.1128/MCB.00161-08. Epub 2008 Jul 28.

11.

The Mcm2-7 complex has in vitro helicase activity.

Bochman ML, Schwacha A.

Mol Cell. 2008 Jul 25;31(2):287-93. doi: 10.1016/j.molcel.2008.05.020.

12.
15.
16.
17.
20.

The nac (nitrogen assimilation control) gene from Klebsiella aerogenes.

Schwacha A, Bender RA.

J Bacteriol. 1993 Apr;175(7):2107-15.

Supplemental Content

Loading ...
Support Center