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Items: 1 to 50 of 652

1.

Effect of Pembrolizumab Plus Neoadjuvant Chemotherapy on Pathologic Complete Response in Women With Early-Stage Breast Cancer: An Analysis of the Ongoing Phase 2 Adaptively Randomized I-SPY2 Trial.

Nanda R, Liu MC, Yau C, Shatsky R, Pusztai L, Wallace A, Chien AJ, Forero-Torres A, Ellis E, Han H, Clark A, Albain K, Boughey JC, Jaskowiak NT, Elias A, Isaacs C, Kemmer K, Helsten T, Majure M, Stringer-Reasor E, Parker C, Lee MC, Haddad T, Cohen RN, Asare S, Wilson A, Hirst GL, Singhrao R, Steeg K, Asare A, Matthews JB, Berry S, Sanil A, Schwab R, Symmans WF, van 't Veer L, Yee D, DeMichele A, Hylton NM, Melisko M, Perlmutter J, Rugo HS, Berry DA, Esserman LJ.

JAMA Oncol. 2020 Feb 13. doi: 10.1001/jamaoncol.2019.6650. [Epub ahead of print]

PMID:
32053137
2.

MK-2206 and Standard Neoadjuvant Chemotherapy Improves Response in Patients With Human Epidermal Growth Factor Receptor 2-Positive and/or Hormone Receptor-Negative Breast Cancers in the I-SPY 2 Trial.

Chien AJ, Tripathy D, Albain KS, Symmans WF, Rugo HS, Melisko ME, Wallace AM, Schwab R, Helsten T, Forero-Torres A, Stringer-Reasor E, Ellis ED, Kaplan HG, Nanda R, Jaskowiak N, Murthy R, Godellas C, Boughey JC, Elias AD, Haley BB, Kemmer K, Isaacs C, Clark AS, Lang JE, Lu J, Korde L, Edmiston KK, Northfelt DW, Viscusi RK, Yee D, Perlmutter J, Hylton NM, Van't Veer LJ, DeMichele A, Wilson A, Peterson G, Buxton MB, Paoloni M, Clennell J, Berry S, Matthews JB, Steeg K, Singhrao R, Hirst GL, Sanil A, Yau C, Asare SM, Berry DA, Esserman LJ; I-SPY 2 Consortium.

J Clin Oncol. 2019 Feb 7:JCO1901027. doi: 10.1200/JCO.19.01027. [Epub ahead of print]

PMID:
32031889
3.

Effect of Weight Loss on Upper Airway Anatomy and the Apnea Hypopnea Index: The Importance of Tongue Fat.

Wang SH, Keenan BT, Wiemken A, Zang Y, Staley B, Sarwer DB, Torigian DA, Williams N, Pack AI, Schwab RJ.

Am J Respir Crit Care Med. 2020 Jan 10. doi: 10.1164/rccm.201903-0692OC. [Epub ahead of print]

PMID:
31918559
4.

Impact of a nurse-led limited risk factor modification program on arrhythmia outcomes in patients with atrial fibrillation undergoing catheter ablation.

Yaeger A, Keenan BT, Cash NR, Parham T, Deo R, Frankel DS, Schaller RD, Santangeli P, Nazarian S, Supple GE, Arkles J, Kumareswaran R, Hyman MC, Riley MP, Garcia FC, Lin D, Epstein AE, Callans DJ, Mora JI, Amaro A, Schwab R, Pack A, Marchlinski FE, Dixit S.

J Cardiovasc Electrophysiol. 2020 Feb;31(2):423-431. doi: 10.1111/jce.14336. Epub 2020 Jan 15.

PMID:
31916273
5.

The impact of intercellular communication for the generation of complex multicellular prevascularized tissue equivalents.

Heller M, Bauer HK, Schwab R, Blatt S, Peters K, Nezi-Cahn S, Unger RE, Hasenburg A, Brenner W.

J Biomed Mater Res A. 2020 Mar;108(3):734-748. doi: 10.1002/jbm.a.36853. Epub 2019 Dec 13.

PMID:
31788941
6.

Program completion and glycemic control in a remote patient monitoring program for diabetes management: Does gender matter?

Michaud TL, Siahpush M, King KM, Ramos AK, Robbins RE, Schwab RJ, Clarke MA, Su D.

Diabetes Res Clin Pract. 2020 Jan;159:107944. doi: 10.1016/j.diabres.2019.107944. Epub 2019 Nov 23.

PMID:
31765684
7.

Differences in Three-Dimensional Upper Airway Anatomy between Asian and European Patients with Obstructive Sleep Apnea.

Xu L, Keenan BT, Wiemken AS, Chi L, Staley B, Wang Z, Wang J, Benedikstdottir B, Juliusson S, Pack AI, Gislason T, Schwab RJ.

Sleep. 2019 Nov 18. pii: zsz273. doi: 10.1093/sleep/zsz273. [Epub ahead of print]

PMID:
31735957
8.

Approaches of T Cell Activation and Differentiation for CAR-T Cell Therapies.

Schwab RD, Bedoya DM, King TR, Levine BL, Posey AD Jr.

Methods Mol Biol. 2020;2086:203-211. doi: 10.1007/978-1-0716-0146-4_15.

PMID:
31707678
9.

Long-term study of the safety and maintenance of efficacy of solriamfetol (JZP-110) in the treatment of excessive sleepiness in participants with narcolepsy or obstructive sleep apnea.

Malhotra A, Shapiro C, Pepin JL, Hedner J, Ahmed M, Foldvary-Schaefer N, Strollo PJ, Mayer G, Sarmiento K, Baladi M, Chandler P, Lee L, Schwab R.

Sleep. 2020 Feb 13;43(2). pii: zsz220. doi: 10.1093/sleep/zsz220.

PMID:
31691827
10.

Resolving intestinal fibrosis through regenerative medicine.

Schwab R, Lim R, Goldberg R.

Curr Opin Pharmacol. 2019 Dec;49:90-94. doi: 10.1016/j.coph.2019.09.011. Epub 2019 Nov 2. Review.

PMID:
31689676
11.

Preventing diabetes with digital health and coaching for translation and scalability (PREDICTS): A type 1 hybrid effectiveness-implementation trial protocol.

Almeida FA, Michaud TL, Wilson KE, Schwab RJ, Goessl C, Porter GC, Brito FA, Evans G, Dressler EV, Boggs AE, Katula JA, Sweet CC, Estabrooks PA.

Contemp Clin Trials. 2020 Jan;88:105877. doi: 10.1016/j.cct.2019.105877. Epub 2019 Nov 1.

PMID:
31682941
12.

Interleukin-36γ-producing macrophages drive IL-17-mediated fibrosis.

Sommerfeld SD, Cherry C, Schwab RM, Chung L, Maestas DR Jr, Laffont P, Stein JE, Tam A, Ganguly S, Housseau F, Taube JM, Pardoll DM, Cahan P, Elisseeff JH.

Sci Immunol. 2019 Oct 11;4(40). pii: eaax4783. doi: 10.1126/sciimmunol.aax4783.

PMID:
31604843
13.

Sequence and Expression Differences Underlie Functional Specialization of Arabidopsis MicroRNAs miR159 and miR319.

Palatnik JF, Wollmann H, Schommer C, Schwab R, Boisbouvier J, Rodriguez R, Warthmann N, Allen E, Dezulian T, Huson D, Carrington JC, Weigel D.

Dev Cell. 2019 Oct 7;51(1):129. doi: 10.1016/j.devcel.2019.09.016. No abstract available.

PMID:
31593649
14.

The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism.

Rudolf AF, Kinnebrew M, Kowatsch C, Ansell TB, El Omari K, Bishop B, Pardon E, Schwab RA, Malinauskas T, Qian M, Duman R, Covey DF, Steyaert J, Wagner A, Sansom MSP, Rohatgi R, Siebold C.

Nat Chem Biol. 2019 Oct;15(10):975-982. doi: 10.1038/s41589-019-0370-y. Epub 2019 Sep 23.

PMID:
31548691
15.

Blood pressure response to treatment of obese vs non-obese adults with sleep apnea.

Kuna ST, Townsend RR, Keenan BT, Maislin D, Gislason T, Benediktsdóttir B, Gudmundsdóttir S, Arnardóttir ES, Sifferman A, Staley B, Pack FM, Guo X, Schwab RJ, Maislin G, Chirinos JA, Pack AI.

J Clin Hypertens (Greenwich). 2019 Oct;21(10):1580-1590. doi: 10.1111/jch.13689. Epub 2019 Sep 18.

16.

Results of the ADHERE upper airway stimulation registry and predictors of therapy efficacy.

Thaler E, Schwab R, Maurer J, Soose R, Larsen C, Stevens S, Stevens D, Boon M, Huntley C, Doghramji K, Waters T, Kominsky A, Steffen A, Kezirian E, Hofauer B, Sommer U, Withrow K, Strohl K, Heiser C.

Laryngoscope. 2019 Sep 14. doi: 10.1002/lary.28286. [Epub ahead of print]

PMID:
31520484
17.

2-Methyl-4-(4-nitro-phen-yl)but-3-yn-2-ol: crystal structure, Hirshfeld surface analysis and computational chemistry study.

Caracelli I, Zukerman-Schpector J, Schwab RS, da Silva EM, Jotani MM, Tiekink ERT.

Acta Crystallogr E Crystallogr Commun. 2019 Jul 23;75(Pt 8):1232-1238. doi: 10.1107/S2056989019010284. eCollection 2019 Aug 1.

18.

Association Between Weight Loss and Glycemic Outcomes: A Post Hoc Analysis of a Remote Patient Monitoring Program for Diabetes Management.

Michaud TL, Siahpush M, Estabrooks P, Schwab RJ, LeVan TD, Grimm B, Ramos AK, Johansson P, Scoggins D, Su D.

Telemed J E Health. 2019 Aug 14. doi: 10.1089/tmj.2019.0030. [Epub ahead of print]

PMID:
31411552
19.

Classifying Patients with Amyotrophic Lateral Sclerosis by Changes in FVC. A Group-based Trajectory Analysis.

Ackrivo J, Hansen-Flaschen J, Jones BL, Wileyto EP, Schwab RJ, Elman L, Kawut SM.

Am J Respir Crit Care Med. 2019 Dec 15;200(12):1513-1521. doi: 10.1164/rccm.201902-0344OC.

20.

HBV-related hepatocarcinogenesis: the role of signalling pathways and innovative ex vivo research models.

Torresi J, Tran BM, Christiansen D, Earnest-Silveira L, Schwab RHM, Vincan E.

BMC Cancer. 2019 Jul 18;19(1):707. doi: 10.1186/s12885-019-5916-6. Review.

21.

The Significance of Visceral Protection in Preventing Enteroatmospheric Fistulae During Open Abdomen Treatment in Patients With Secondary Peritonitis: A Propensity Score-matched Case-control Analysis.

Willms AG, Schaaf S, Zimmermann N, Schwab R, Güsgen C, Vilz TO, Kalff JC, von Websky MW.

Ann Surg. 2019 Jul 15. doi: 10.1097/SLA.0000000000003440. [Epub ahead of print]

PMID:
31318792
22.

MRI evaluation of cerebrovascular reactivity in obstructive sleep apnea.

Wu PH, Rodríguez-Soto AE, Rodgers ZB, Englund EK, Wiemken A, Langham MC, Detre JA, Schwab RJ, Guo W, Wehrli FW.

J Cereb Blood Flow Metab. 2019 Jul 15:271678X19862182. doi: 10.1177/0271678X19862182. [Epub ahead of print]

PMID:
31307289
23.

EXD2 Protects Stressed Replication Forks and Is Required for Cell Viability in the Absence of BRCA1/2.

Nieminuszczy J, Broderick R, Bellani MA, Smethurst E, Schwab RA, Cherdyntseva V, Evmorfopoulou T, Lin YL, Minczuk M, Pasero P, Gagos S, Seidman MM, Niedzwiedz W.

Mol Cell. 2019 Aug 8;75(3):605-619.e6. doi: 10.1016/j.molcel.2019.05.026. Epub 2019 Jun 26.

24.

Wing flexibility reduces the energetic requirements of insect flight.

Reid HE, Schwab RK, Maxcer M, Peterson RKD, Johnson EL, Jankauski M.

Bioinspir Biomim. 2019 Jul 29;14(5):056007. doi: 10.1088/1748-3190/ab2dbc.

PMID:
31252414
25.

Previous Surgery and Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea.

Kezirian EJ, Heiser C, Steffen A, Boon M, Hofauer B, Doghramji K, Maurer JT, Sommer JU, Soose RJ, Schwab R, Thaler E, Withrow K, Kominsky A, Larsen CG, Hsia J, Mehra R, Waters T, Strohl K.

Otolaryngol Head Neck Surg. 2019 Nov;161(5):897-903. doi: 10.1177/0194599819856339. Epub 2019 Jun 25.

PMID:
31234734
26.

Revisiting Epidermal Growth Factor Receptor (EGFR) Amplification as a Target for Anti-EGFR Therapy: Analysis of Cell-Free Circulating Tumor DNA in Patients With Advanced Malignancies.

Kato S, Okamura R, Mareboina M, Lee S, Goodman A, Patel SP, Fanta PT, Schwab RB, Vu P, Raymond VM, Lanman RB, Sicklick JK, Lippman SM, Kurzrock R.

JCO Precis Oncol. 2019;3. doi: 10.1200/PO.18.00180. Epub 2019 Jan 22.

27.

A Global Comparison of Anatomic Risk Factors and Their Relationship to Obstructive Sleep Apnea Severity in Clinical Samples.

Sutherland K, Keenan BT, Bittencourt L, Chen NH, Gislason T, Leinwand S, Magalang UJ, Maislin G, Mazzotti DR, McArdle N, Mindel J, Pack AI, Penzel T, Singh B, Tufik S, Schwab RJ, Cistulli PA; SAGIC Investigators.

J Clin Sleep Med. 2019 Apr 15;15(4):629-639. doi: 10.5664/jcsm.7730.

28.

Next-Generation Sequencing of Tissue and Circulating Tumor DNA: The UC San Diego Moores Center for Personalized Cancer Therapy Experience with Breast Malignancies.

Shatsky R, Parker BA, Bui NQ, Helsten T, Schwab RB, Boles SG, Kurzrock R.

Mol Cancer Ther. 2019 May;18(5):1001-1011. doi: 10.1158/1535-7163.MCT-17-1038. Epub 2019 Mar 29.

PMID:
30926636
29.

[SMAR3T©-a new time-saving diagnostic emergency room management algorithm].

Waldeck S, Franke A, Güsgen C, Schwab R, Kalff J, Pantelis D.

Chirurg. 2019 Oct;90(10):845-850. doi: 10.1007/s00104-019-0811-x. German.

PMID:
30888436
30.

Development of a prognostic model of respiratory insufficiency or death in amyotrophic lateral sclerosis.

Ackrivo J, Hansen-Flaschen J, Wileyto EP, Schwab RJ, Elman L, Kawut SM.

Eur Respir J. 2019 Apr 18;53(4). pii: 1802237. doi: 10.1183/13993003.02237-2018. Print 2019 Apr.

31.

Concept Paper on the Technique of Cryopreservation, Removal and Transplantation of Ovarian Tissue for Fertility Preservation.

Beckmann MW, Lotz L, Toth B, Baston-Büst DM, Fehm T, Frambach T, Germeyer A, Goeckenjan M, Häberlin F, Henes M, Hirchenhain J, Hübner S, Korell M, Krüssel JS, Müller A, Reinsberg J, Schwab R, Seitz S, Sütterlin M, van der Ven H, van der Ven K, Winkler-Crepaz K, Wimberger P, von Wolff M, Liebenthron J, Dittrich R.

Geburtshilfe Frauenheilkd. 2019 Jan;79(1):53-62. doi: 10.1055/a-0664-8619. Epub 2018 Oct 9.

32.

Exploring the landscape of focal amplifications in cancer using AmpliconArchitect.

Deshpande V, Luebeck J, Nguyen ND, Bakhtiari M, Turner KM, Schwab R, Carter H, Mischel PS, Bafna V.

Nat Commun. 2019 Jan 23;10(1):392. doi: 10.1038/s41467-018-08200-y.

33.

Chemical genetic identification of a lectin receptor kinase that transduces immune responses and interferes with abscisic acid signaling.

Park J, Kim TH, Takahashi Y, Schwab R, Dressano K, Stephan AB, Ceciliato PHO, Ramirez E, Garin V, Huffaker A, Schroeder JI.

Plant J. 2019 May;98(3):492-510. doi: 10.1111/tpj.14232. Epub 2019 Mar 7.

PMID:
30659683
34.

Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody.

Zhang S, Zhang H, Ghia EM, Huang J, Wu L, Zhang J, Lam S, Lei Y, He J, Cui B, Widhopf GF 2nd, Yu J, Schwab R, Messer K, Jiang W, Parker BA, Carson DA, Kipps TJ.

Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1370-1377. doi: 10.1073/pnas.1816262116. Epub 2019 Jan 8.

35.

A Nurse-Led Limited Risk Factor Modification Program to Address Obesity and Obstructive Sleep Apnea in Atrial Fibrillation Patients.

Yaeger A, Cash NR, Parham T, Frankel DS, Deo R, Schaller RD, Santangeli P, Nazarian S, Supple GE, Arkles J, Riley MP, Garcia FC, Lin D, Epstein AE, Callans DJ, Marchlinski FE, Kolansky DM, Mora JI, Amaro A, Schwab R, Pack A, Dixit S.

J Am Heart Assoc. 2018 Dec 4;7(23):e010414. doi: 10.1161/JAHA.118.010414.

36.

Primary Mucosal Epithelial Cell Cultivation: A Reliable and Accelerated Isolation.

Bauer HK, Flesch D, Walenta S, Unger RE, Schwab R, Nezi-Cahn S, Hasenburg A, Heller M, Brenner W.

Tissue Eng Part C Methods. 2019 Feb;25(2):82-92. doi: 10.1089/ten.TEC.2018.0327.

PMID:
30501564
37.

Post-approval upper airway stimulation predictors of treatment effectiveness in the ADHERE registry.

Heiser C, Steffen A, Boon M, Hofauer B, Doghramji K, Maurer JT, Sommer JU, Soose R, Strollo PJ Jr, Schwab R, Thaler E, Withrow K, Kominsky A, Larsen C, Kezirian EJ, Hsia J, Chia S, Harwick J, Strohl K, Mehra R; ADHERE registry investigators.

Eur Respir J. 2019 Jan 3;53(1). pii: 1801405. doi: 10.1183/13993003.01405-2018. Print 2019 Jan.

38.

Histopathologic quantification of viable tumor versus treatment effect in surgically resected recurrent glioblastoma.

Bagley SJ, Schwab RD, Nelson E, Viaene AN, Binder ZA, Lustig RA, O'Rourke DM, Brem S, Desai AS, Nasrallah MP.

J Neurooncol. 2019 Jan;141(2):421-429. doi: 10.1007/s11060-018-03050-6. Epub 2018 Nov 16.

PMID:
30446903
39.

Author Correction: The structure of the ubiquitin-like modifier FAT10 reveals an alternative targeting mechanism for proteasomal degradation.

Aichem A, Anders S, Catone N, Rößler P, Stotz S, Berg A, Schwab R, Scheuermann S, Bialas J, Schütz-Stoffregen MC, Schmidtke G, Peter C, Groettrup M, Wiesner S.

Nat Commun. 2018 Nov 2;9(1):4646. doi: 10.1038/s41467-018-07183-0.

40.

Pitfalls in interpretation of large registry data on hernia repair.

Schwab R, Dietz UA, Menzel S, Wiegering A.

Hernia. 2018 Dec;22(6):947-950. doi: 10.1007/s10029-018-1837-6. Epub 2018 Nov 1.

PMID:
30386922
41.

Diabetes Management Through Remote Patient Monitoring: The Importance of Patient Activation and Engagement with the Technology.

Su D, Michaud TL, Estabrooks P, Schwab RJ, Eiland LA, Hansen G, DeVany M, Zhang D, Li Y, Pagán JA, Siahpush M.

Telemed J E Health. 2019 Oct;25(10):952-959. doi: 10.1089/tmj.2018.0205. Epub 2018 Oct 27.

PMID:
30372366
42.

Breast Cancer Mortality in Older and Younger Patients in California.

Tao L, Schwab RB, San Miguel Y, Gomez SL, Canchola AJ, Gago-Dominguez M, Komenaka IK, Murphy JD, Molinolo AA, Martinez ME.

Cancer Epidemiol Biomarkers Prev. 2019 Feb;28(2):303-310. doi: 10.1158/1055-9965.EPI-18-0353. Epub 2018 Oct 17.

43.

Modulation of ACD6 dependent hyperimmunity by natural alleles of an Arabidopsis thaliana NLR resistance gene.

Zhu W, Zaidem M, Van de Weyer AL, Gutaker RM, Chae E, Kim ST, Bemm F, Li L, Todesco M, Schwab R, Unger F, Beha MJ, Demar M, Weigel D.

PLoS Genet. 2018 Sep 20;14(9):e1007628. doi: 10.1371/journal.pgen.1007628. eCollection 2018 Sep.

44.

4-(4-Acetyl-5-methyl-1H-1,2,3-triazol-1-yl)benzo-nitrile: crystal structure and Hirshfeld surface analysis.

Zukerman-Schpector J, Dias CDS, Schwab RS, Jotani MM, Tiekink ERT.

Acta Crystallogr E Crystallogr Commun. 2018 Aug 10;74(Pt 9):1195-1200. doi: 10.1107/S2056989018010885. eCollection 2018 Sep 1.

45.

EHS clinical guidelines on the management of the abdominal wall in the context of the open or burst abdomen.

López-Cano M, García-Alamino JM, Antoniou SA, Bennet D, Dietz UA, Ferreira F, Fortelny RH, Hernandez-Granados P, Miserez M, Montgomery A, Morales-Conde S, Muysoms F, Pereira JA, Schwab R, Slater N, Vanlander A, Van Ramshorst GH, Berrevoet F.

Hernia. 2018 Dec;22(6):921-939. doi: 10.1007/s10029-018-1818-9. Epub 2018 Sep 3. Review.

PMID:
30178226
46.

When Transfusion Is Not an Option-the Challenges and Rewards.

Schwab R, Kosoglow M, Philp FH, Suydam E.

Crit Care Nurs Q. 2018 Oct/Dec;41(4):347-355. doi: 10.1097/CNQ.0000000000000219.

PMID:
30153176
47.

The structure of the ubiquitin-like modifier FAT10 reveals an alternative targeting mechanism for proteasomal degradation.

Aichem A, Anders S, Catone N, Rößler P, Stotz S, Berg A, Schwab R, Scheuermann S, Bialas J, Schütz-Stoffregen MC, Schmidtke G, Peter C, Groettrup M, Wiesner S.

Nat Commun. 2018 Aug 20;9(1):3321. doi: 10.1038/s41467-018-05776-3. Erratum in: Nat Commun. 2018 Nov 2;9(1):4646.

48.

An efficient CRISPR vector toolbox for engineering large deletions in Arabidopsis thaliana.

Wu R, Lucke M, Jang YT, Zhu W, Symeonidi E, Wang C, Fitz J, Xi W, Schwab R, Weigel D.

Plant Methods. 2018 Aug 2;14:65. doi: 10.1186/s13007-018-0330-7. eCollection 2018.

49.

Image-based methods for phenotyping growth dynamics and fitness components in Arabidopsis thaliana.

Vasseur F, Bresson J, Wang G, Schwab R, Weigel D.

Plant Methods. 2018 Jul 26;14:63. doi: 10.1186/s13007-018-0331-6. eCollection 2018.

50.

Dynamic Upper Airway Imaging during Wakefulness in Obese Subjects with and without Sleep Apnea.

Feng Y, Keenan BT, Wang S, Leinwand S, Wiemken A, Pack AI, Schwab RJ.

Am J Respir Crit Care Med. 2018 Dec 1;198(11):1435-1443. doi: 10.1164/rccm.201711-2171OC.

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