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Items: 1 to 50 of 117

1.

Intervention protocol: OPtimising thERapy to prevent avoidable hospital Admission in the Multi-morbid elderly (OPERAM): a structured medication review with support of a computerised decision support system.

Crowley EK, Sallevelt BTGM, Huibers CJA, Murphy KD, Spruit M, Shen Z, Boland B, Spinewine A, Dalleur O, Moutzouri E, Löwe A, Feller M, Schwab N, Adam L, Wilting I, Knol W, Rodondi N, Byrne S, O'Mahony D.

BMC Health Serv Res. 2020 Mar 17;20(1):220. doi: 10.1186/s12913-020-5056-3.

2.

Patient values and preferences regarding VTE disease: a systematic review to inform American Society of Hematology guidelines.

Etxeandia-Ikobaltzeta I, Zhang Y, Brundisini F, Florez ID, Wiercioch W, Nieuwlaat R, Begum H, Cuello CA, Roldan Y, Chen R, Ding C, Morgan RL, Riva JJ, Zhang Y, Charide R, Agarwal A, Balduzzi S, Morgano GP, Yepes-Nuñez JJ, Rehman Y, Neumann I, Schwab N, Baldeh T, Braun C, Rodríguez MF, Schünemann HJ.

Blood Adv. 2020 Mar 10;4(5):953-968. doi: 10.1182/bloodadvances.2019000462.

3.

Next-Generation Neuroimmunology: New Technologies to Understand Central Nervous System Autoimmunity.

Meyer Zu Hörste G, Gross CC, Klotz L, Schwab N, Wiendl H.

Trends Immunol. 2020 Apr;41(4):341-354. doi: 10.1016/j.it.2020.02.005. Epub 2020 Mar 5. Review.

4.

CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome.

Gross CC, Meyer C, Bhatia U, Yshii L, Kleffner I, Bauer J, Tröscher AR, Schulte-Mecklenbeck A, Herich S, Schneider-Hohendorf T, Plate H, Kuhlmann T, Schwaninger M, Brück W, Pawlitzki M, Laplaud DA, Loussouarn D, Parratt J, Barnett M, Buckland ME, Hardy TA, Reddel SW, Ringelstein M, Dörr J, Wildemann B, Kraemer M, Lassmann H, Höftberger R, Beltrán E, Dornmair K, Schwab N, Klotz L, Meuth SG, Martin-Blondel G, Wiendl H, Liblau R.

Nat Commun. 2019 Dec 18;10(1):5779. doi: 10.1038/s41467-019-13593-5.

5.
6.

DNA repair deficiency and senescence in concussed professional athletes involved in contact sports.

Schwab N, Grenier K, Hazrati LN.

Acta Neuropathol Commun. 2019 Nov 14;7(1):182. doi: 10.1186/s40478-019-0822-3.

7.

Ineffective treatment of PML with pembrolizumab: Exhausted memory T-cell subsets as a clue?

Pawlitzki M, Schneider-Hohendorf T, Rolfes L, Meuth SG, Wiendl H, Schwab N, Grauer OM.

Neurol Neuroimmunol Neuroinflamm. 2019 Oct 9;6(6):e627. doi: 10.1212/NXI.0000000000000627. Print 2019 Nov. No abstract available.

8.

Human CCR5high effector memory cells perform CNS parenchymal immune surveillance via GZMK-mediated transendothelial diapedesis.

Herich S, Schneider-Hohendorf T, Rohlmann A, Khaleghi Ghadiri M, Schulte-Mecklenbeck A, Zondler L, Janoschka C, Ostkamp P, Richter J, Breuer J, Dimitrov S, Rammensee HG, Grauer OM, Klotz L, Gross CC, Stummer W, Missler M, Zarbock A, Vestweber D, Wiendl H, Schwab N.

Brain. 2019 Nov 1;142(11):3411-3427. doi: 10.1093/brain/awz301.

PMID:
31563951
9.

'Optimising PharmacoTherapy In the multimorbid elderly in primary CAre' (OPTICA) to improve medication appropriateness: study protocol of a cluster randomised controlled trial.

Jungo KT, Rozsnyai Z, Mantelli S, Floriani C, Löwe AL, Lindemann F, Schwab N, Meier R, Elloumi L, Huibers CJA, Sallevelt BTGM, Meulendijk MC, Reeve E, Feller M, Schneider C, Bhend H, Bürki PM, Trelle S, Spruit M, Schwenkglenks M, Rodondi N, Streit S.

BMJ Open. 2019 Sep 3;9(9):e031080. doi: 10.1136/bmjopen-2019-031080.

10.

Prospective validation of the PML risk biomarker l-selectin and influence of natalizumab extended intervals.

Schwab N, Schneider-Hohendorf T, Pignolet B, Bucciarelli F, Scandella L, Ciron J, Biotti D, Lebrun-Frenay C, Mathey G, Clavelou P, Pelletier J, Ostkamp P, Meinl I, Windhagen S, Klotz L, Gross CC, Meuth SG, Deisenhammer F, Brassat D, Wiendl H; Best-MS Study Group.

Neurology. 2019 Sep 17;93(12):550-554. doi: 10.1212/WNL.0000000000008135. Epub 2019 Aug 22. No abstract available.

PMID:
31439633
11.

Extensive immune reconstitution inflammatory syndrome in Fingolimod-associated PML: a case report with 7 Tesla MRI data.

Sinnecker T, Hadisurya J, Schneider-Hohendorf T, Schwab N, Wrede K, Gembruch O, Gold R, Hellwig K, Pilgram-Pastor S, Adams O, Albrecht P, Hartung HP, Aktas O, Kraemer M.

BMC Neurol. 2019 Aug 9;19(1):190. doi: 10.1186/s12883-019-1407-2.

12.

Rationale and design of OPtimising thERapy to prevent Avoidable hospital admissions in Multimorbid older people (OPERAM): a cluster randomised controlled trial.

Adam L, Moutzouri E, Baumgartner C, Loewe AL, Feller M, M'Rabet-Bensalah K, Schwab N, Hossmann S, Schneider C, Jegerlehner S, Floriani C, Limacher A, Jungo KT, Huibers CJA, Streit S, Schwenkglenks M, Spruit M, Van Dorland A, Donzé J, Kearney PM, Jüni P, Aujesky D, Jansen P, Boland B, Dalleur O, Byrne S, Knol W, Spinewine A, O'Mahony D, Trelle S, Rodondi N.

BMJ Open. 2019 Jun 3;9(6):e026769. doi: 10.1136/bmjopen-2018-026769.

13.

Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects.

Klotz L, Eschborn M, Lindner M, Liebmann M, Herold M, Janoschka C, Torres Garrido B, Schulte-Mecklenbeck A, Gross CC, Breuer J, Hundehege P, Posevitz V, Pignolet B, Nebel G, Glander S, Freise N, Austermann J, Wirth T, Campbell GR, Schneider-Hohendorf T, Eveslage M, Brassat D, Schwab N, Loser K, Roth J, Busch KB, Stoll M, Mahad DJ, Meuth SG, Turner T, Bar-Or A, Wiendl H.

Sci Transl Med. 2019 May 1;11(490). pii: eaao5563. doi: 10.1126/scitranslmed.aao5563.

PMID:
31043571
14.

Hamate's coronal fracture: diagnostic and therapeutic approaches based on a long-term follow-up.

Eder C, Scheller A, Schwab N, Krapohl BD.

GMS Interdiscip Plast Reconstr Surg DGPW. 2019 Mar 29;8:Doc05. doi: 10.3205/iprs000131. eCollection 2019.

15.

Risks and risk management in modern multiple sclerosis immunotherapeutic treatment.

Klotz L, Havla J, Schwab N, Hohlfeld R, Barnett M, Reddel S, Wiendl H.

Ther Adv Neurol Disord. 2019 Apr 1;12:1756286419836571. doi: 10.1177/1756286419836571. eCollection 2019. Review.

16.

Natalizumab-associated progressive multifocal leukoencephalopathy in Germany.

Blankenbach K, Schwab N, Hofner B, Adams O, Keller-Stanislawski B, Warnke C.

Neurology. 2019 May 7;92(19):e2232-e2239. doi: 10.1212/WNL.0000000000007451. Epub 2019 Apr 5.

PMID:
30952796
17.

Structural brain correlates of fatigue in older adults with and without Parkinson's disease.

Kluger BM, Zhao Q, Tanner JJ, Schwab NA, Levy SA, Burke SE, Huang H, Ding M, Price C.

Neuroimage Clin. 2019;22:101730. doi: 10.1016/j.nicl.2019.101730. Epub 2019 Feb 21.

18.

VLA-2 blockade in vivo by vatelizumab induces CD4+FoxP3+ regulatory T cells.

Breuer J, Schneider-Hohendorf T, Ostkamp P, Herich S, Rakhade S, Antonijevic I, Klotz L, Wiendl H, Schwab N.

Int Immunol. 2019 May 21;31(6):407-412. doi: 10.1093/intimm/dxz018.

PMID:
30783682
19.

DNA damage as a marker of brain damage in individuals with history of concussions.

Schwab N, Tator C, Hazrati LN.

Lab Invest. 2019 Jul;99(7):1008-1018. doi: 10.1038/s41374-019-0199-8. Epub 2019 Feb 13.

PMID:
30760862
20.

Dietary salt promotes ischemic brain injury and is associated with parenchymal migrasome formation.

Schmidt-Pogoda A, Strecker JK, Liebmann M, Massoth C, Beuker C, Hansen U, König S, Albrecht S, Bock S, Breuer J, Sommer C, Schwab N, Wiendl H, Klotz L, Minnerup J.

PLoS One. 2018 Dec 27;13(12):e0209871. doi: 10.1371/journal.pone.0209871. eCollection 2018.

21.

American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy.

Bates SM, Rajasekhar A, Middeldorp S, McLintock C, Rodger MA, James AH, Vazquez SR, Greer IA, Riva JJ, Bhatt M, Schwab N, Barrett D, LaHaye A, Rochwerg B.

Blood Adv. 2018 Nov 27;2(22):3317-3359. doi: 10.1182/bloodadvances.2018024802.

22.

American Society of Hematology 2018 Guidelines for management of venous thromboembolism: treatment of pediatric venous thromboembolism.

Monagle P, Cuello CA, Augustine C, Bonduel M, Brandão LR, Capman T, Chan AKC, Hanson S, Male C, Meerpohl J, Newall F, O'Brien SH, Raffini L, van Ommen H, Wiernikowski J, Williams S, Bhatt M, Riva JJ, Roldan Y, Schwab N, Mustafa RA, Vesely SK.

Blood Adv. 2018 Nov 27;2(22):3292-3316. doi: 10.1182/bloodadvances.2018024786.

23.

Flavonifractor (Eubacterium) plautii bloodstream infection following acute cholecystitis.

Berger FK, Schwab N, Glanemann M, Bohle RM, Gärtner B, Groesdonk HV.

IDCases. 2018 Oct 28;14:e00461. doi: 10.1016/j.idcr.2018.e00461. eCollection 2018.

24.

From eyes-closed to eyes-open: Role of cholinergic projections in EC-to-EO alpha reactivity revealed by combining EEG and MRI.

Wan L, Huang H, Schwab N, Tanner J, Rajan A, Lam NB, Zaborszky L, Li CR, Price CC, Ding M.

Hum Brain Mapp. 2019 Feb 1;40(2):566-577. doi: 10.1002/hbm.24395. Epub 2018 Sep 25.

25.

Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus.

Breuer J, Korpos E, Hannocks MJ, Schneider-Hohendorf T, Song J, Zondler L, Herich S, Flanagan K, Korn T, Zarbock A, Kuhlmann T, Sorokin L, Wiendl H, Schwab N.

J Neuroinflammation. 2018 Aug 22;15(1):236. doi: 10.1186/s12974-018-1276-4.

26.

Regional leukoaraiosis and cognition in non-demented older adults.

Wiggins ME, Tanner J, Schwab N, Crowley SJ, Schmalfuss I, Brumback B, Libon DJ, Heilman K, Price CC.

Brain Imaging Behav. 2019 Oct;13(5):1246-1254. doi: 10.1007/s11682-018-9938-5.

PMID:
30128647
27.

Immune Cell Profiling During Switching from Natalizumab to Fingolimod Reveals Differential Effects on Systemic Immune-Regulatory Networks and on Trafficking of Non-T Cell Populations into the Cerebrospinal Fluid-Results from the ToFingo Successor Study.

Lohmann L, Janoschka C, Schulte-Mecklenbeck A, Klinsing S, Kirstein L, Hanning U, Wirth T, Schneider-Hohendorf T, Schwab N, Gross CC, Eveslage M, Meuth SG, Wiendl H, Klotz L.

Front Immunol. 2018 Jul 9;9:1560. doi: 10.3389/fimmu.2018.01560. eCollection 2018.

28.

Assessing the Limitations and Biases in the Current Understanding of Chronic Traumatic Encephalopathy.

Schwab N, Hazrati LN.

J Alzheimers Dis. 2018;64(4):1067-1076. doi: 10.3233/JAD-180373. Review.

PMID:
30010133
29.

Does the environment influence multiple sclerosis pathogenesis via UVB light and/or induction of vitamin D?

Breuer J, Loser K, Mykicki N, Wiendl H, Schwab N.

J Neuroimmunol. 2019 Apr 15;329:1-8. doi: 10.1016/j.jneuroim.2018.05.006. Epub 2018 May 18. Review.

PMID:
29793727
30.

Sex bias in MHC I-associated shaping of the adaptive immune system.

Schneider-Hohendorf T, Görlich D, Savola P, Kelkka T, Mustjoki S, Gross CC, Owens GC, Klotz L, Dornmair K, Wiendl H, Schwab N.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):2168-2173. doi: 10.1073/pnas.1716146115. Epub 2018 Feb 12.

31.

Nitazoxanide May Modify the Course of Progressive Multifocal Leukoencephalopathy.

Hautala TJ, Perelygina L, Vuorinen T, Hautala NM, Hägg PM, Bode MK, Rusanen HT, Renko MH, Glumoff V, Schwab N, Schneider-Hohendorf T, Murk JL, Sullivan KE, Seppänen MRJ.

J Clin Immunol. 2018 Jan;38(1):4-6. doi: 10.1007/s10875-017-0463-x. Epub 2017 Nov 20. No abstract available.

32.

Dual action by fumaric acid esters synergistically reduces adhesion to human endothelium.

Breuer J, Herich S, Schneider-Hohendorf T, Chasan AI, Wettschureck N, Gross CC, Loser K, Zarbock A, Roth J, Klotz L, Wiendl H, Schwab N.

Mult Scler. 2017 Oct 1:1352458517735189. doi: 10.1177/1352458517735189. [Epub ahead of print]

PMID:
28984166
33.

Reliability and Utility of Manual and Automated Estimates of Total Intracranial Volume.

Crowley SJ, Tanner JJ, Ramon D, Schwab NA, Hizel LP, Price CC.

J Int Neuropsychol Soc. 2018 Feb;24(2):206-211. doi: 10.1017/S1355617717000868. Epub 2017 Oct 5.

34.

Liver X receptor activation promotes differentiation of regulatory T cells.

Herold M, Breuer J, Hucke S, Knolle P, Schwab N, Wiendl H, Klotz L.

PLoS One. 2017 Sep 19;12(9):e0184985. doi: 10.1371/journal.pone.0184985. eCollection 2017.

35.

Anti-JCV serology during natalizumab treatment: Review and meta-analysis of 17 independent patient cohorts analyzing anti-John Cunningham polyoma virus sero-conversion rates under natalizumab treatment and differences between technical and biological sero-converters.

Schwab N, Schneider-Hohendorf T, Hoyt T, Gross CC, Meuth SG, Klotz L, Foley JF, Wiendl H.

Mult Scler. 2018 Apr;24(5):563-573. doi: 10.1177/1352458517728814. Epub 2017 Aug 29. Review.

PMID:
28847222
36.

Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation.

Tischner D, Grimm M, Kaur H, Staudenraus D, Carvalho J, Looso M, Günther S, Wanke F, Moos S, Siller N, Breuer J, Schwab N, Zipp F, Waisman A, Kurschus FC, Offermanns S, Wettschureck N.

JCI Insight. 2017 Aug 3;2(15). pii: 95063. doi: 10.1172/jci.insight.95063. eCollection 2017 Aug 3.

37.

Chemokine CCL17 is expressed by dendritic cells in the CNS during experimental autoimmune encephalomyelitis and promotes pathogenesis of disease.

Ruland C, Renken H, Kuzmanov I, Fattahi Mehr A, Schwarte K, Cerina M, Herrmann A, Otte DM, Zimmer A, Schwab N, Meuth SG, Arolt V, Klotz L, Förster I, Scheu S, Alferink J.

Brain Behav Immun. 2017 Nov;66:382-393. doi: 10.1016/j.bbi.2017.06.010. Epub 2017 Jun 19.

PMID:
28642092
38.

Analysis of Lymphocyte Extravasation Using an In Vitro Model of the Human Blood-brain Barrier.

Schulte-Mecklenbeck A, Bhatia U, Schneider-Hohendorf T, Schwab N, Wiendl H, Gross CC.

J Vis Exp. 2017 Apr 5;(122). doi: 10.3791/55390.

39.

Mapping Dorsal and Ventral Caudate in Older Adults: Method and Validation.

Huang H, Nguyen PT, Schwab NA, Tanner JJ, Price CC, Ding M.

Front Aging Neurosci. 2017 Apr 4;9:91. doi: 10.3389/fnagi.2017.00091. eCollection 2017.

40.

Neuroticism as a risk factor for child abuse in victims of childhood sexual abuse.

Boillat C, Schwab N, Stutz M, Pflueger MO, Graf M, Rosburg T.

Child Abuse Negl. 2017 Jun;68:44-54. doi: 10.1016/j.chiabu.2017.03.018. Epub 2017 Apr 7.

PMID:
28395194
41.

Erratum to: Considering total intracranial volume and other nuisance variables in brain voxel based morphometry in idiopathic PD.

Crowley S, Huang H, Tanner J, Zhao Q, Schwab NA, Hizel L, Ramon D, Brumback B, Ding M, Price CC.

Brain Imaging Behav. 2018 Apr;12(2):613. doi: 10.1007/s11682-017-9709-8. No abstract available.

PMID:
28341871
42.

Natalizumab-associated PML: Challenges with incidence, resulting risk, and risk stratification.

Schwab N, Schneider-Hohendorf T, Melzer N, Cutter G, Wiendl H.

Neurology. 2017 Mar 21;88(12):1197-1205. doi: 10.1212/WNL.0000000000003739. Epub 2017 Feb 22. Review.

PMID:
28228564
43.

Considering total intracranial volume and other nuisance variables in brain voxel based morphometry in idiopathic PD.

Crowley S, Huang H, Tanner J, Zhao Q, Schwab NA, Hizel L, Ramon D, Brumback B, Ding M, Price CC.

Brain Imaging Behav. 2018 Feb;12(1):1-12. doi: 10.1007/s11682-016-9656-9. Erratum in: Brain Imaging Behav. 2017 Mar 24;:.

44.

CD62L test at 2 years of natalizumab predicts progressive multifocal leukoencephalopathy.

Pignolet B, Schwab N, Schneider-Hohendorf T, Bucciarelli F, Biotti D, Averseng-Peaureaux D, Outteryck O, Ongagna JC, de Sèze J, Brochet B, Ouallet JC, Debouverie M, Pittion S, Defer G, Derache N, Hautecoeur P, Tourbah A, Labauge P, Castelnovo G, Clavelou P, Berger E, Pelletier J, Rico A, Zéphir H, Laplaud D, Wiertlewski S, Camu W, Thouvenot E, Casez O, Moreau T, Fromont A, Vukusic S, Papeix C, Vermersch P, Comabella M, Lebrun-Frenay C, Wiendl H, Brassat D; BIONAT, SFSEP, and BEST-MS networks.

Neurology. 2016 Dec 6;87(23):2491-2494. Epub 2016 Nov 4. No abstract available.

PMID:
27815407
45.

Marked brain asymmetry with intact cognitive functioning in idiopathic Parkinson's disease: a longitudinal analysis.

Tanner JJ, Levy SA, Schwab NA, Hizel LP, Nguyen PT, Okun MS, Price CC.

Clin Neuropsychol. 2017 Apr;31(3):654-675. doi: 10.1080/13854046.2016.1251973. Epub 2016 Nov 4.

46.

Melanocortin-1 receptor activation is neuroprotective in mouse models of neuroinflammatory disease.

Mykicki N, Herrmann AM, Schwab N, Deenen R, Sparwasser T, Limmer A, Wachsmuth L, Klotz L, Köhrer K, Faber C, Wiendl H, Luger TA, Meuth SG, Loser K.

Sci Transl Med. 2016 Oct 26;8(362):362ra146.

PMID:
27797962
47.

Direct Visualization of Neurotransmitters in Rat Brain Slices by Desorption Electrospray Ionization Mass Spectrometry Imaging (DESI - MS).

Fernandes AM, Vendramini PH, Galaverna R, Schwab NV, Alberici LC, Augusti R, Castilho RF, Eberlin MN.

J Am Soc Mass Spectrom. 2016 Dec;27(12):1944-1951. Epub 2016 Oct 4.

PMID:
27704473
48.

B7-H1 shapes T-cell-mediated brain endothelial cell dysfunction and regional encephalitogenicity in spontaneous CNS autoimmunity.

Klotz L, Kuzmanov I, Hucke S, Gross CC, Posevitz V, Dreykluft A, Schulte-Mecklenbeck A, Janoschka C, Lindner M, Herold M, Schwab N, Ludwig-Portugall I, Kurts C, Meuth SG, Kuhlmann T, Wiendl H.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6182-E6191. Epub 2016 Sep 26.

49.

CD62L is not a reliable biomarker for predicting PML risk in natalizumab-treated R-MS patients.

Schwab N, Schneider-Hohendorf T, Wiendl H.

Neurology. 2016 Aug 30;87(9):958-9. doi: 10.1212/01.wnl.0000496643.57775.41. No abstract available.

PMID:
27572431
50.

Distinct pattern of lesion distribution in multiple sclerosis is associated with different circulating T-helper and helper-like innate lymphoid cell subsets.

Gross CC, Schulte-Mecklenbeck A, Hanning U, Posevitz-Fejfár A, Korsukewitz C, Schwab N, Meuth SG, Wiendl H, Klotz L.

Mult Scler. 2017 Jun;23(7):1025-1030. doi: 10.1177/1352458516662726. Epub 2016 Aug 1.

PMID:
27481205

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