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Items: 1 to 50 of 106

1.

Rationale and design of OPtimising thERapy to prevent Avoidable hospital admissions in Multimorbid older people (OPERAM): a cluster randomised controlled trial.

Adam L, Moutzouri E, Baumgartner C, Loewe AL, Feller M, M'Rabet-Bensalah K, Schwab N, Hossmann S, Schneider C, Jegerlehner S, Floriani C, Limacher A, Jungo KT, Huibers CJA, Streit S, Schwenkglenks M, Spruit M, Van Dorland A, Donzé J, Kearney PM, Jüni P, Aujesky D, Jansen P, Boland B, Dalleur O, Byrne S, Knol W, Spinewine A, O'Mahony D, Trelle S, Rodondi N.

BMJ Open. 2019 Jun 3;9(6):e026769. doi: 10.1136/bmjopen-2018-026769.

2.

Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects.

Klotz L, Eschborn M, Lindner M, Liebmann M, Herold M, Janoschka C, Torres Garrido B, Schulte-Mecklenbeck A, Gross CC, Breuer J, Hundehege P, Posevitz V, Pignolet B, Nebel G, Glander S, Freise N, Austermann J, Wirth T, Campbell GR, Schneider-Hohendorf T, Eveslage M, Brassat D, Schwab N, Loser K, Roth J, Busch KB, Stoll M, Mahad DJ, Meuth SG, Turner T, Bar-Or A, Wiendl H.

Sci Transl Med. 2019 May 1;11(490). pii: eaao5563. doi: 10.1126/scitranslmed.aao5563.

PMID:
31043571
3.

Hamate's coronal fracture: diagnostic and therapeutic approaches based on a long-term follow-up.

Eder C, Scheller A, Schwab N, Krapohl BD.

GMS Interdiscip Plast Reconstr Surg DGPW. 2019 Mar 29;8:Doc05. doi: 10.3205/iprs000131. eCollection 2019.

4.

Risks and risk management in modern multiple sclerosis immunotherapeutic treatment.

Klotz L, Havla J, Schwab N, Hohlfeld R, Barnett M, Reddel S, Wiendl H.

Ther Adv Neurol Disord. 2019 Apr 1;12:1756286419836571. doi: 10.1177/1756286419836571. eCollection 2019. Review.

5.

Natalizumab-associated progressive multifocal leukoencephalopathy in Germany.

Blankenbach K, Schwab N, Hofner B, Adams O, Keller-Stanislawski B, Warnke C.

Neurology. 2019 May 7;92(19):e2232-e2239. doi: 10.1212/WNL.0000000000007451. Epub 2019 Apr 5.

PMID:
30952796
6.

Structural brain correlates of fatigue in older adults with and without Parkinson's disease.

Kluger BM, Zhao Q, Tanner JJ, Schwab NA, Levy SA, Burke SE, Huang H, Ding M, Price C.

Neuroimage Clin. 2019;22:101730. doi: 10.1016/j.nicl.2019.101730. Epub 2019 Feb 21.

7.

VLA-2 blockade in vivo by vatelizumab induces CD4+FoxP3+ regulatory T cells.

Breuer J, Schneider-Hohendorf T, Ostkamp P, Herich S, Rakhade S, Antonijevic I, Klotz L, Wiendl H, Schwab N.

Int Immunol. 2019 May 21;31(6):407-412. doi: 10.1093/intimm/dxz018.

PMID:
30783682
8.

DNA damage as a marker of brain damage in individuals with history of concussions.

Schwab N, Tator C, Hazrati LN.

Lab Invest. 2019 Feb 13. doi: 10.1038/s41374-019-0199-8. [Epub ahead of print]

PMID:
30760862
9.

Dietary salt promotes ischemic brain injury and is associated with parenchymal migrasome formation.

Schmidt-Pogoda A, Strecker JK, Liebmann M, Massoth C, Beuker C, Hansen U, König S, Albrecht S, Bock S, Breuer J, Sommer C, Schwab N, Wiendl H, Klotz L, Minnerup J.

PLoS One. 2018 Dec 27;13(12):e0209871. doi: 10.1371/journal.pone.0209871. eCollection 2018.

10.

American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy.

Bates SM, Rajasekhar A, Middeldorp S, McLintock C, Rodger MA, James AH, Vazquez SR, Greer IA, Riva JJ, Bhatt M, Schwab N, Barrett D, LaHaye A, Rochwerg B.

Blood Adv. 2018 Nov 27;2(22):3317-3359. doi: 10.1182/bloodadvances.2018024802. Review.

11.

American Society of Hematology 2018 Guidelines for management of venous thromboembolism: treatment of pediatric venous thromboembolism.

Monagle P, Cuello CA, Augustine C, Bonduel M, Brandão LR, Capman T, Chan AKC, Hanson S, Male C, Meerpohl J, Newall F, O'Brien SH, Raffini L, van Ommen H, Wiernikowski J, Williams S, Bhatt M, Riva JJ, Roldan Y, Schwab N, Mustafa RA, Vesely SK.

Blood Adv. 2018 Nov 27;2(22):3292-3316. doi: 10.1182/bloodadvances.2018024786. Review.

12.

Flavonifractor (Eubacterium) plautii bloodstream infection following acute cholecystitis.

Berger FK, Schwab N, Glanemann M, Bohle RM, Gärtner B, Groesdonk HV.

IDCases. 2018 Oct 28;14:e00461. doi: 10.1016/j.idcr.2018.e00461. eCollection 2018.

13.

From eyes-closed to eyes-open: Role of cholinergic projections in EC-to-EO alpha reactivity revealed by combining EEG and MRI.

Wan L, Huang H, Schwab N, Tanner J, Rajan A, Lam NB, Zaborszky L, Li CR, Price CC, Ding M.

Hum Brain Mapp. 2019 Feb 1;40(2):566-577. doi: 10.1002/hbm.24395. Epub 2018 Sep 25.

PMID:
30251753
14.

Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus.

Breuer J, Korpos E, Hannocks MJ, Schneider-Hohendorf T, Song J, Zondler L, Herich S, Flanagan K, Korn T, Zarbock A, Kuhlmann T, Sorokin L, Wiendl H, Schwab N.

J Neuroinflammation. 2018 Aug 22;15(1):236. doi: 10.1186/s12974-018-1276-4.

15.

Regional leukoaraiosis and cognition in non-demented older adults.

Wiggins ME, Tanner J, Schwab N, Crowley SJ, Schmalfuss I, Brumback B, Libon DJ, Heilman K, Price CC.

Brain Imaging Behav. 2018 Aug 20. doi: 10.1007/s11682-018-9938-5. [Epub ahead of print]

PMID:
30128647
16.

Immune Cell Profiling During Switching from Natalizumab to Fingolimod Reveals Differential Effects on Systemic Immune-Regulatory Networks and on Trafficking of Non-T Cell Populations into the Cerebrospinal Fluid-Results from the ToFingo Successor Study.

Lohmann L, Janoschka C, Schulte-Mecklenbeck A, Klinsing S, Kirstein L, Hanning U, Wirth T, Schneider-Hohendorf T, Schwab N, Gross CC, Eveslage M, Meuth SG, Wiendl H, Klotz L.

Front Immunol. 2018 Jul 9;9:1560. doi: 10.3389/fimmu.2018.01560. eCollection 2018.

17.

Assessing the Limitations and Biases in the Current Understanding of Chronic Traumatic Encephalopathy.

Schwab N, Hazrati LN.

J Alzheimers Dis. 2018;64(4):1067-1076. doi: 10.3233/JAD-180373.

PMID:
30010133
18.

Does the environment influence multiple sclerosis pathogenesis via UVB light and/or induction of vitamin D?

Breuer J, Loser K, Mykicki N, Wiendl H, Schwab N.

J Neuroimmunol. 2019 Apr 15;329:1-8. doi: 10.1016/j.jneuroim.2018.05.006. Epub 2018 May 18. Review.

PMID:
29793727
19.

Sex bias in MHC I-associated shaping of the adaptive immune system.

Schneider-Hohendorf T, Görlich D, Savola P, Kelkka T, Mustjoki S, Gross CC, Owens GC, Klotz L, Dornmair K, Wiendl H, Schwab N.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):2168-2173. doi: 10.1073/pnas.1716146115. Epub 2018 Feb 12.

20.

Nitazoxanide May Modify the Course of Progressive Multifocal Leukoencephalopathy.

Hautala TJ, Perelygina L, Vuorinen T, Hautala NM, Hägg PM, Bode MK, Rusanen HT, Renko MH, Glumoff V, Schwab N, Schneider-Hohendorf T, Murk JL, Sullivan KE, Seppänen MRJ.

J Clin Immunol. 2018 Jan;38(1):4-6. doi: 10.1007/s10875-017-0463-x. Epub 2017 Nov 20. No abstract available.

PMID:
29159786
21.

Dual action by fumaric acid esters synergistically reduces adhesion to human endothelium.

Breuer J, Herich S, Schneider-Hohendorf T, Chasan AI, Wettschureck N, Gross CC, Loser K, Zarbock A, Roth J, Klotz L, Wiendl H, Schwab N.

Mult Scler. 2017 Oct 1:1352458517735189. doi: 10.1177/1352458517735189. [Epub ahead of print]

PMID:
28984166
22.

Reliability and Utility of Manual and Automated Estimates of Total Intracranial Volume.

Crowley SJ, Tanner JJ, Ramon D, Schwab NA, Hizel LP, Price CC.

J Int Neuropsychol Soc. 2018 Feb;24(2):206-211. doi: 10.1017/S1355617717000868. Epub 2017 Oct 5.

PMID:
28978362
23.

Liver X receptor activation promotes differentiation of regulatory T cells.

Herold M, Breuer J, Hucke S, Knolle P, Schwab N, Wiendl H, Klotz L.

PLoS One. 2017 Sep 19;12(9):e0184985. doi: 10.1371/journal.pone.0184985. eCollection 2017.

24.

Anti-JCV serology during natalizumab treatment: Review and meta-analysis of 17 independent patient cohorts analyzing anti-John Cunningham polyoma virus sero-conversion rates under natalizumab treatment and differences between technical and biological sero-converters.

Schwab N, Schneider-Hohendorf T, Hoyt T, Gross CC, Meuth SG, Klotz L, Foley JF, Wiendl H.

Mult Scler. 2018 Apr;24(5):563-573. doi: 10.1177/1352458517728814. Epub 2017 Aug 29.

PMID:
28847222
25.

Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation.

Tischner D, Grimm M, Kaur H, Staudenraus D, Carvalho J, Looso M, Günther S, Wanke F, Moos S, Siller N, Breuer J, Schwab N, Zipp F, Waisman A, Kurschus FC, Offermanns S, Wettschureck N.

JCI Insight. 2017 Aug 3;2(15). pii: 95063. doi: 10.1172/jci.insight.95063. eCollection 2017 Aug 3.

26.

Chemokine CCL17 is expressed by dendritic cells in the CNS during experimental autoimmune encephalomyelitis and promotes pathogenesis of disease.

Ruland C, Renken H, Kuzmanov I, Fattahi Mehr A, Schwarte K, Cerina M, Herrmann A, Otte DM, Zimmer A, Schwab N, Meuth SG, Arolt V, Klotz L, Förster I, Scheu S, Alferink J.

Brain Behav Immun. 2017 Nov;66:382-393. doi: 10.1016/j.bbi.2017.06.010. Epub 2017 Jun 19.

PMID:
28642092
27.

Analysis of Lymphocyte Extravasation Using an In Vitro Model of the Human Blood-brain Barrier.

Schulte-Mecklenbeck A, Bhatia U, Schneider-Hohendorf T, Schwab N, Wiendl H, Gross CC.

J Vis Exp. 2017 Apr 5;(122). doi: 10.3791/55390.

28.

Mapping Dorsal and Ventral Caudate in Older Adults: Method and Validation.

Huang H, Nguyen PT, Schwab NA, Tanner JJ, Price CC, Ding M.

Front Aging Neurosci. 2017 Apr 4;9:91. doi: 10.3389/fnagi.2017.00091. eCollection 2017.

29.

Neuroticism as a risk factor for child abuse in victims of childhood sexual abuse.

Boillat C, Schwab N, Stutz M, Pflueger MO, Graf M, Rosburg T.

Child Abuse Negl. 2017 Jun;68:44-54. doi: 10.1016/j.chiabu.2017.03.018. Epub 2017 Apr 7.

PMID:
28395194
30.

Erratum to: Considering total intracranial volume and other nuisance variables in brain voxel based morphometry in idiopathic PD.

Crowley S, Huang H, Tanner J, Zhao Q, Schwab NA, Hizel L, Ramon D, Brumback B, Ding M, Price CC.

Brain Imaging Behav. 2018 Apr;12(2):613. doi: 10.1007/s11682-017-9709-8. No abstract available.

PMID:
28341871
31.

Natalizumab-associated PML: Challenges with incidence, resulting risk, and risk stratification.

Schwab N, Schneider-Hohendorf T, Melzer N, Cutter G, Wiendl H.

Neurology. 2017 Mar 21;88(12):1197-1205. doi: 10.1212/WNL.0000000000003739. Epub 2017 Feb 22. Review.

PMID:
28228564
32.

Considering total intracranial volume and other nuisance variables in brain voxel based morphometry in idiopathic PD.

Crowley S, Huang H, Tanner J, Zhao Q, Schwab NA, Hizel L, Ramon D, Brumback B, Ding M, Price CC.

Brain Imaging Behav. 2018 Feb;12(1):1-12. doi: 10.1007/s11682-016-9656-9. Erratum in: Brain Imaging Behav. 2017 Mar 24;:.

33.

CD62L test at 2 years of natalizumab predicts progressive multifocal leukoencephalopathy.

Pignolet B, Schwab N, Schneider-Hohendorf T, Bucciarelli F, Biotti D, Averseng-Peaureaux D, Outteryck O, Ongagna JC, de Sèze J, Brochet B, Ouallet JC, Debouverie M, Pittion S, Defer G, Derache N, Hautecoeur P, Tourbah A, Labauge P, Castelnovo G, Clavelou P, Berger E, Pelletier J, Rico A, Zéphir H, Laplaud D, Wiertlewski S, Camu W, Thouvenot E, Casez O, Moreau T, Fromont A, Vukusic S, Papeix C, Vermersch P, Comabella M, Lebrun-Frenay C, Wiendl H, Brassat D; BIONAT, SFSEP, and BEST-MS networks.

Neurology. 2016 Dec 6;87(23):2491-2494. Epub 2016 Nov 4. No abstract available.

PMID:
27815407
34.

Marked brain asymmetry with intact cognitive functioning in idiopathic Parkinson's disease: a longitudinal analysis.

Tanner JJ, Levy SA, Schwab NA, Hizel LP, Nguyen PT, Okun MS, Price CC.

Clin Neuropsychol. 2017 Apr;31(3):654-675. doi: 10.1080/13854046.2016.1251973. Epub 2016 Nov 4.

35.

Melanocortin-1 receptor activation is neuroprotective in mouse models of neuroinflammatory disease.

Mykicki N, Herrmann AM, Schwab N, Deenen R, Sparwasser T, Limmer A, Wachsmuth L, Klotz L, Köhrer K, Faber C, Wiendl H, Luger TA, Meuth SG, Loser K.

Sci Transl Med. 2016 Oct 26;8(362):362ra146.

PMID:
27797962
36.

Direct Visualization of Neurotransmitters in Rat Brain Slices by Desorption Electrospray Ionization Mass Spectrometry Imaging (DESI - MS).

Fernandes AM, Vendramini PH, Galaverna R, Schwab NV, Alberici LC, Augusti R, Castilho RF, Eberlin MN.

J Am Soc Mass Spectrom. 2016 Dec;27(12):1944-1951. Epub 2016 Oct 4.

PMID:
27704473
37.

B7-H1 shapes T-cell-mediated brain endothelial cell dysfunction and regional encephalitogenicity in spontaneous CNS autoimmunity.

Klotz L, Kuzmanov I, Hucke S, Gross CC, Posevitz V, Dreykluft A, Schulte-Mecklenbeck A, Janoschka C, Lindner M, Herold M, Schwab N, Ludwig-Portugall I, Kurts C, Meuth SG, Kuhlmann T, Wiendl H.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6182-E6191. Epub 2016 Sep 26.

38.

CD62L is not a reliable biomarker for predicting PML risk in natalizumab-treated R-MS patients.

Schwab N, Schneider-Hohendorf T, Wiendl H.

Neurology. 2016 Aug 30;87(9):958-9. doi: 10.1212/01.wnl.0000496643.57775.41. No abstract available.

PMID:
27572431
39.

Distinct pattern of lesion distribution in multiple sclerosis is associated with different circulating T-helper and helper-like innate lymphoid cell subsets.

Gross CC, Schulte-Mecklenbeck A, Hanning U, Posevitz-Fejfár A, Korsukewitz C, Schwab N, Meuth SG, Wiendl H, Klotz L.

Mult Scler. 2017 Jun;23(7):1025-1030. doi: 10.1177/1352458516662726. Epub 2016 Aug 1.

PMID:
27481205
40.

Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation.

Gross CC, Schulte-Mecklenbeck A, Rünzi A, Kuhlmann T, Posevitz-Fejfár A, Schwab N, Schneider-Hohendorf T, Herich S, Held K, Konjević M, Hartwig M, Dornmair K, Hohlfeld R, Ziemssen T, Klotz L, Meuth SG, Wiendl H.

Proc Natl Acad Sci U S A. 2016 May 24;113(21):E2973-82. doi: 10.1073/pnas.1524924113. Epub 2016 May 9.

41.

CD8(+) T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing.

Schneider-Hohendorf T, Mohan H, Bien CG, Breuer J, Becker A, Görlich D, Kuhlmann T, Widman G, Herich S, Elpers C, Melzer N, Dornmair K, Kurlemann G, Wiendl H, Schwab N.

Nat Commun. 2016 Apr 4;7:11153. doi: 10.1038/ncomms11153.

42.

Molecular manipulation of keratin 8/18 intermediate filaments: modulators of FAS-mediated death signaling in human ovarian granulosa tumor cells.

Trisdale SK, Schwab NM, Hou X, Davis JS, Townson DH.

J Ovarian Res. 2016 Feb 24;9:8. doi: 10.1186/s13048-016-0217-z.

43.

Therapy with natalizumab is associated with high JCV seroconversion and rising JCV index values.

Schwab N, Schneider-Hohendorf T, Pignolet B, Breuer J, Gross CC, Göbel K, Brassat D, Wiendl H.

Neurol Neuroimmunol Neuroinflamm. 2016 Jan 27;3(1):e195. doi: 10.1212/NXI.0000000000000195. eCollection 2016 Feb.

44.

Gray and White Matter Contributions to Cognitive Frontostriatal Deficits in Non-Demented Parkinson's Disease.

Price CC, Tanner J, Nguyen PT, Schwab NA, Mitchell S, Slonena E, Brumback B, Okun MS, Mareci TH, Bowers D.

PLoS One. 2016 Jan 19;11(1):e0147332. doi: 10.1371/journal.pone.0147332. eCollection 2016.

45.

A dopant for improved sensitivity in easy ambient sonic-spray ionization mass spectrometry.

Santos JM, Vendramini PH, Schwab NV, Eberlin MN, de Morais DR.

J Mass Spectrom. 2016 Jan;51(1):53-61. doi: 10.1002/jms.3726.

PMID:
26757072
46.

Clustering of worry appraisals among college students.

Schwab NG, Cullum JC, Harton HC.

J Soc Psychol. 2016 Jul-Aug;156(4):413-21. doi: 10.1080/00224545.2015.1115387. Epub 2015 Nov 5.

PMID:
26541710
47.

A new variant of scaphoid reconstruction: Treatment of scaphoid non-union with avascular bone interponate and high compression screw (Synthes(®)).

Eder C, Schwab N, Scheller A, Krapohl BD.

GMS Interdiscip Plast Reconstr Surg DGPW. 2015 Aug 24;4:Doc07. doi: 10.3205/iprs000066. eCollection 2015.

48.

PML risk stratification using anti-JCV antibody index and L-selectin.

Schwab N, Schneider-Hohendorf T, Pignolet B, Spadaro M, Görlich D, Meinl I, Windhagen S, Tackenberg B, Breuer J, Cantó E, Kümpfel T, Hohlfeld R, Siffrin V, Luessi F, Posevitz-Fejfár A, Montalban X, Meuth SG, Zipp F, Gold R, Du Pasquier RA, Kleinschnitz C, Jacobi A, Comabella M, Bertolotto A, Brassat D, Wiendl H.

Mult Scler. 2016 Jul;22(8):1048-60. doi: 10.1177/1352458515607651. Epub 2015 Oct 2.

PMID:
26432858
49.

Trafficking of lymphocytes into the CNS.

Schwab N, Schneider-Hohendorf T, Wiendl H.

Oncotarget. 2015 Jul 20;6(20):17863-4. No abstract available.

50.

Assessment of immune functions and MRI disease activity in relapsing-remitting multiple sclerosis patients switching from natalizumab to fingolimod (ToFingo-Successor).

Klotz L, Grützke B, Eveslage M, Deppe M, Gross CC, Kirstein L, Posevitz-Fejfar A, Schneider-Hohendorf T, Schwab N, Meuth SG, Wiendl H.

BMC Neurol. 2015 Jun 23;15:96. doi: 10.1186/s12883-015-0354-9.

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