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Items: 1 to 50 of 1548

1.

Prevention of fluoropyrimidine toxicity: do we still have to try our patient's luck?

Danesi R, Del Re M, Ciccolini J, Schellens JHM, Schwab M, van Schaik RHN, van Kuilenburg ABP.

Ann Oncol. 2017 Jan 1;28(1):183. doi: 10.1093/annonc/mdw448. No abstract available.

PMID:
31792513
2.

Copy number variation profiling in pharmacogenes using panel-based exome resequencing and correlation to human liver expression.

Tremmel R, Klein K, Battke F, Fehr S, Winter S, Scheurenbrand T, Schaeffeler E, Biskup S, Schwab M, Zanger UM.

Hum Genet. 2019 Nov 30. doi: 10.1007/s00439-019-02093-7. [Epub ahead of print]

PMID:
31786673
3.

Acute onset and severe manifestation of postural orthostatic tachycardia syndrome - Two cases.

Chung HY, Essig F, Wickel J, Besteher B, Neugebauer H, Haeusler KG, Müllges W, Schwab M.

Clin Neurophysiol. 2019 Nov 11;131(1):158-159. doi: 10.1016/j.clinph.2019.11.001. [Epub ahead of print] No abstract available.

PMID:
31778914
4.

Characterization of laser-driven proton acceleration from water microdroplets.

Becker GA, Schwab MB, Lötzsch R, Tietze S, Klöpfel D, Rehwald M, Schlenvoigt HP, Sävert A, Schramm U, Zepf M, Kaluza MC.

Sci Rep. 2019 Nov 20;9(1):17169. doi: 10.1038/s41598-019-53587-3.

5.

An 82-Year-Old Man With Sleep-Onset Insomnia, Breathing Arrest, and Heart Failure.

de la Motte T, Schwab M, Schultze T, Witte OW, Rupprecht S.

Chest. 2019 Nov;156(5):e95-e98. doi: 10.1016/j.chest.2019.05.044.

PMID:
31699235
6.

Global Pharmacogenomics Within Precision Medicine: Challenges and Opportunities.

Chenoweth MJ, Giacomini KM, Pirmohamed M, Hill SL, van Schaik RHN, Schwab M, Shuldiner AR, Relling MV, Tyndale RF.

Clin Pharmacol Ther. 2019 Nov 6. doi: 10.1002/cpt.1664. [Epub ahead of print] No abstract available.

PMID:
31696505
7.

Reprogramming of DNA methylation at NEUROD2-bound sequences during cortical neuron differentiation.

Hahn MA, Jin SG, Li AX, Liu J, Huang Z, Wu X, Kim BW, Johnson J, Bilbao AV, Tao S, Yim JA, Fong Y, Goebbels S, Schwab MH, Lu Q, Pfeifer GP.

Sci Adv. 2019 Oct 23;5(10):eaax0080. doi: 10.1126/sciadv.aax0080. eCollection 2019 Oct.

8.

Acute Encephalopathy and Cardiac Arrest Induced by Intrathecal Gadolinium Administration.

Besteher B, Chung HY, Mayer TE, Witte OW, Kirchhof K, Schwab M.

Clin Neuroradiol. 2019 Nov 2. doi: 10.1007/s00062-019-00845-6. [Epub ahead of print] No abstract available.

PMID:
31679044
9.

One non-believer: Response to "Obviously Nine Believers: Actionable Germline Genetic Variants for Pre-emptive Pharmacogenetic Testing".

van der Wouden CH, van Rhenen MH, Jama WOM, Ingelman-Sundberg M, Lauschke VM, Konta L, Schwab M, Swen JJ, Guchelaar HJ.

Basic Clin Pharmacol Toxicol. 2019 Oct 31. doi: 10.1111/bcpt.13336. [Epub ahead of print] No abstract available.

PMID:
31670867
10.

[Design and Evaluation of a Clinical Investigator Training for Student-lead Prospective Multicentre Clinical Trials: a CHIR-Net SIGMA Research-based Learning Project].

Rädeker L, Schwab M, Frey PE, Friedrich M, Sliwinski S, Steinle J, Fink CA, Leuk A, Ganschow P, Ottawa GB, Klose C, Feißt M, Dörr-Harim C, Tenckhoff S, Mihaljevic AL.

Zentralbl Chir. 2019 Oct 28. doi: 10.1055/a-1007-1995. [Epub ahead of print] German.

PMID:
31658485
11.

Context-dependent limb movement encoding in neuronal populations of motor cortex.

Omlor W, Wahl AS, Sipilä P, Lütcke H, Laurenczy B, Chen IW, Sumanovski LT, van 't Hoff M, Bethge P, Voigt FF, Schwab ME, Helmchen F.

Nat Commun. 2019 Oct 23;10(1):4812. doi: 10.1038/s41467-019-12670-z.

12.

The Impact of CYP3A4*22 on Tacrolimus Pharmacokinetics and Outcome in Clinical Practice at a Single Kidney Transplant Center.

Abdel-Kahaar E, Winter S, Tremmel R, Schaeffeler E, Olbricht CJ, Wieland E, Schwab M, Shipkova M, Jaeger SU.

Front Genet. 2019 Sep 26;10:871. doi: 10.3389/fgene.2019.00871. eCollection 2019.

13.

Variability and Heritability of Thiamine Pharmacokinetics With Focus on OCT1 Effects on Membrane Transport and Pharmacokinetics in Humans.

Jensen O, Matthaei J, Blome F, Schwab M, Tzvetkov MV, Brockmöller J.

Clin Pharmacol Ther. 2019 Oct 8. doi: 10.1002/cpt.1666. [Epub ahead of print]

PMID:
31593619
14.

The Influences of Adherence to Tamoxifen and CYP2D6 Pharmacogenetics on Plasma Concentrations of the Active Metabolite (Z)-Endoxifen in Breast Cancer.

Nardin JM, Schroth W, Almeida TA, Mürdter T, Picolotto S, Vendramini ECL, Hoppe R, Kogin JP, Miqueleto D, de Moraes SDR, Schwab M, Pecoits-Filho RF, Brauch H, Casali-da-Rocha JC.

Clin Transl Sci. 2019 Oct 1. doi: 10.1111/cts.12707. [Epub ahead of print]

PMID:
31573754
15.

Radiosensitization of HSF-1 Knockdown Lung Cancer Cells by Low Concentrations of Hsp90 Inhibitor NVP-AUY922.

Kühnel A, Schilling D, Combs SE, Haller B, Schwab M, Multhoff G.

Cells. 2019 Sep 28;8(10). pii: E1166. doi: 10.3390/cells8101166.

16.

Enhancing rehabilitation and functional recovery after brain and spinal cord trauma with electrical neuromodulation.

Hofer AS, Schwab ME.

Curr Opin Neurol. 2019 Dec;32(6):828-835. doi: 10.1097/WCO.0000000000000750.

PMID:
31567546
17.

Platelet surface expression of cyclophilin A is associated with increased mortality in patients with symptomatic coronary artery disease.

Rath D, von Ungern-Sternberg S, Heinzmann D, Sigle M, Monzien M, Horstmann K, Schaeffeler E, Winter S, Müller K, Groga-Bada P, Zdanyte M, Borst O, Zernecke A, Gawaz M, Martus P, Schwab M, Geisler T, Seizer P.

J Thromb Haemost. 2019 Sep 13. doi: 10.1111/jth.14635. [Epub ahead of print]

PMID:
31519036
18.

Pharmacogenomic Polygenic Response Score Predicts Ischemic Events and Cardiovascular Mortality in Clopidogrel-Treated Patients.

Lewis JP, Backman JD, Reny JL, Bergmeijer TO, Mitchell BD, Ritchie MD, Déry JP, Pakyz RE, Gong L, Ryan K, Kim EY, Aradi D, Fernandez-Cadenas I, Lee MTM, Whaley RM, Montaner J, Gensini GF, Cleator JH, Chang K, Holmvang L, Hochholzer W, Roden DM, Winter S, Altman R, Alexopoulos D, Kim HS, Gawaz M, Bliden K, Valgimigli M, Marcucci R, Campo G, Schaeffeler E, Dridi NP, Wen MS, Shin JG, Fontana P, Giusti B, Geisler T, Kubo M, Trenk D, Siller-Matula JM, Ten Berg JM, Gurbel PA, Schwab M, Klein TE, Shuldiner AR.

Eur Heart J Cardiovasc Pharmacother. 2019 Sep 3. pii: pvz045. doi: 10.1093/ehjcvp/pvz045. [Epub ahead of print]

PMID:
31504375
19.

Maternal psychosocial stress during early gestation impairs fetal structural brain development in sheep.

Hermes M, Antonow-Schlorke I, Hollstein D, Kuehnel S, Rakers F, Frauendorf V, Dreiling M, Rupprecht S, Schubert H, Witte OW, Schwab M.

Stress. 2019 Aug 30:1-10. doi: 10.1080/10253890.2019.1652266. [Epub ahead of print]

PMID:
31469022
20.

Combined with anti-Nogo-A antibody treatment, BDNF did not compensate the extra deleterious motor effect caused by large size cervical cord hemisection in adult macaques.

Beaud ML, Rouiller EM, Bloch J, Mir A, Schwab ME, Schmidlin E.

CNS Neurosci Ther. 2019 Aug 16. doi: 10.1111/cns.13213. [Epub ahead of print]

PMID:
31418518
21.

Late-life brain perfusion after prenatal famine exposure.

de Rooij SR, Mutsaerts HJMM, Petr J, Asllani I, Caan MWA, Groot P, Nederveen AJ, Schwab M, Roseboom TJ.

Neurobiol Aging. 2019 Oct;82:1-9. doi: 10.1016/j.neurobiolaging.2019.06.012. Epub 2019 Jul 8.

PMID:
31376728
22.

Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1.

Chen M, Neul C, Schaeffeler E, Frisch F, Winter S, Schwab M, Koepsell H, Hu S, Laufer S, Baker SD, Sparreboom A, Nies AT.

Clin Pharmacol Ther. 2019 Jul 27. doi: 10.1002/cpt.1588. [Epub ahead of print]

PMID:
31350763
23.

Identification of novel agonists by high-throughput screening and molecular modelling of human constitutive androstane receptor isoform 3.

Keminer O, Windshügel B, Essmann F, Lee SML, Schiergens TS, Schwab M, Burk O.

Arch Toxicol. 2019 Aug;93(8):2247-2264. doi: 10.1007/s00204-019-02495-6. Epub 2019 Jul 16.

PMID:
31312845
24.

Refueling the Ischemic CNS: Guidance Molecules for Vascular Repair.

Rust R, Grönnert L, Weber RZ, Mulders G, Schwab ME.

Trends Neurosci. 2019 Sep;42(9):644-656. doi: 10.1016/j.tins.2019.05.006. Epub 2019 Jul 5. Review.

PMID:
31285047
25.

Pancreatic stenting to prevent post-ERCP pancreatitis: a randomized multicenter trial.

Phillip V, Pukitis A, Epstein A, Hapfelmeier A, Haf D, Schwab M, Demir IE, Rosendahl J, Hoffmeister A, Schmid RM, Weber A, Algül H.

Endosc Int Open. 2019 Jul;7(7):E860-E868. doi: 10.1055/a-0886-6384. Epub 2019 Jul 3.

26.

High-Resolution PET Cisternography With 64Cu-DOTA for CSF Leak Detection.

Freesmeyer M, Schwab M, Besteher B, Gröber S, Waschke A, Drescher R.

Clin Nucl Med. 2019 Sep;44(9):735-737. doi: 10.1097/RLU.0000000000002695.

PMID:
31274554
27.

Pharmacogenomics education in medical and pharmacy schools: conclusions of a global survey.

Karas Kuželički N, Prodan Žitnik I, Gurwitz D, Llerena A, Cascorbi I, Siest S, Simmaco M, Ansari M, Pazzagli M, Di Resta C, Brandslund I, Schwab M, Vermeersch P, Lunshof JE, Dedoussis G, Flordellis CS, Fuhr U, Stingl JC, van Schaik RH, Manolopoulos VG, Marc J; Pharmacogenomics Education Working Group (PGxEWG); European Society of Pharmacogenomics and Personalized Therapy (ESPT).

Pharmacogenomics. 2019 Jun;20(9):643-657. doi: 10.2217/pgs-2019-0009.

28.

A Clinical Drug-Drug Interaction Study Assessing a Novel Drug Transporter Phenotyping Cocktail With Adefovir, Sitagliptin, Metformin, Pitavastatin, and Digoxin.

Trueck C, Hsin CH, Scherf-Clavel O, Schaeffeler E, Lenssen R, Gazzaz M, Gersie M, Taubert M, Quasdorff M, Schwab M, Kinzig M, Sörgel F, Stoffel MS, Fuhr U.

Clin Pharmacol Ther. 2019 Dec;106(6):1398-1407. doi: 10.1002/cpt.1564. Epub 2019 Aug 12.

PMID:
31247117
29.

Nogo-A targeted therapy promotes vascular repair and functional recovery following stroke.

Rust R, Grönnert L, Gantner C, Enzler A, Mulders G, Weber RZ, Siewert A, Limasale YDP, Meinhardt A, Maurer MA, Sartori AM, Hofer AS, Werner C, Schwab ME.

Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14270-14279. doi: 10.1073/pnas.1905309116. Epub 2019 Jun 24.

PMID:
31235580
30.

Corrigendum: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy.

Belin S, Ornaghi F, Shackleford G, Wang J, Scapin C, Lopez-Anido C, Silvestri N, Robertson N, Williamson C, Ishii A, Taveggia C, Svaren J, Bansal R, Schwab MH, Nave K, Fratta P, D'Antonio M, Poitelon Y, Feltri ML, Wrabetz L.

Hum Mol Genet. 2019 Jul 1;28(13):2282. doi: 10.1093/hmg/ddz037. No abstract available.

31.

The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes.

Pattschull G, Walz S, Gründl M, Schwab M, Rühl E, Baluapuri A, Cindric-Vranesic A, Kneitz S, Wolf E, Ade CP, Rosenwald A, von Eyss B, Gaubatz S.

Cell Rep. 2019 Jun 18;27(12):3533-3546.e7. doi: 10.1016/j.celrep.2019.05.071.

32.

Tamoxifen Pharmacogenetics and Metabolism: The Same Is Not the Same.

Brauch H, Schroth W, Mürdter T, Schwab M.

J Clin Oncol. 2019 Aug 1;37(22):1981-1982. doi: 10.1200/JCO.19.00507. Epub 2019 Jun 18. No abstract available.

PMID:
31211600
33.

Intranasal Administration of Mesenchymal Stem Cells Ameliorates the Abnormal Dopamine Transmission System and Inflammatory Reaction in the R6/2 Mouse Model of Huntington Disease.

Yu-Taeger L, Stricker-Shaver J, Arnold K, Bambynek-Dziuk P, Novati A, Singer E, Lourhmati A, Fabian C, Magg J, Riess O, Schwab M, Stolzing A, Danielyan L, Nguyen HHP.

Cells. 2019 Jun 15;8(6). pii: E595. doi: 10.3390/cells8060595.

34.

Corticotectal Projections From the Premotor or Primary Motor Cortex After Cortical Lesion or Parkinsonian Symptoms in Adult Macaque Monkeys: A Pilot Tracing Study.

Fregosi M, Contestabile A, Badoud S, Borgognon S, Cottet J, Brunet JF, Bloch J, Schwab ME, Rouiller EM.

Front Neuroanat. 2019 May 22;13:50. doi: 10.3389/fnana.2019.00050. eCollection 2019.

35.

Clinical Trial: CYP2D6 Related Dose Escalation of Tamoxifen in Breast Cancer Patients With Iranian Ethnic Background Resulted in Increased Concentrations of Tamoxifen and Its Metabolites.

Khalaj Z, Baratieh Z, Nikpour P, Schwab M, Schaeffeler E, Mokarian F, Khanahmad H, Salehi R, Mürdter TE, Salehi M.

Front Pharmacol. 2019 May 24;10:530. doi: 10.3389/fphar.2019.00530. eCollection 2019.

36.

Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole.

Türk D, Hanke N, Wolf S, Frechen S, Eissing T, Wendl T, Schwab M, Lehr T.

Clin Pharmacokinet. 2019 Dec;58(12):1595-1607. doi: 10.1007/s40262-019-00777-x.

PMID:
31129789
37.

Evaluation of biological and enzymatic quorum quencher coating additives to reduce biocorrosion of steel.

Huang S, Bergonzi C, Schwab M, Elias M, Hicks RE.

PLoS One. 2019 May 16;14(5):e0217059. doi: 10.1371/journal.pone.0217059. eCollection 2019.

38.

Association Between Systemic Inflammation, Carotid Arteriosclerosis, and Autonomic Dysfunction.

Rupprecht S, Finn S, Hoyer D, Guenther A, Witte OW, Schultze T, Schwab M.

Transl Stroke Res. 2019 May 16. doi: 10.1007/s12975-019-00706-x. [Epub ahead of print]

PMID:
31093927
39.

A smart peek: Processing of rapid visual displays is disturbed in newly diagnosed, cognitively intact MS patients and refers to cognitive performance and disease progression in late stages.

Fischer M, Köhler W, Faiss JH, Hoffmann F, Kunkel A, Sailer M, Schwab M, Zettl UK, Bublak P; HIPPOCOMS Study Group.

J Neurol Sci. 2019 Jun 15;401:118-124. doi: 10.1016/j.jns.2019.04.031. Epub 2019 Apr 23.

PMID:
31075683
40.

RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas.

Wirthschaft P, Bode J, Soni H, Dietrich F, Krüwel T, Fischer B, Knobbe-Thomsen CB, Rossetti G, Hentschel A, Mack N, Schönig K, Breckwoldt MO, Schmandke A, Pusch S, Medenbach J, Bendszus M, Schwab ME, von Deimling A, Kool M, Herold-Mende C, Reifenberger G, Ahrends R, Tews B.

Acta Neuropathol. 2019 Aug;138(2):275-293. doi: 10.1007/s00401-019-02021-z. Epub 2019 May 6.

41.

Development of the PGx-Passport: A Panel of Actionable Germline Genetic Variants for Pre-Emptive Pharmacogenetic Testing.

van der Wouden CH, van Rhenen MH, Jama WOM, Ingelman-Sundberg M, Lauschke VM, Konta L, Schwab M, Swen JJ, Guchelaar HJ.

Clin Pharmacol Ther. 2019 Oct;106(4):866-873. doi: 10.1002/cpt.1489. Epub 2019 Jun 12.

42.

Measuring broader wellbeing in mental health services: validity of the German language OxCAP-MH capability instrument.

Łaszewska A, Schwab M, Leutner E, Oberrauter M, Spiel G, Simon J.

Qual Life Res. 2019 Aug;28(8):2311-2323. doi: 10.1007/s11136-019-02187-9. Epub 2019 Apr 27.

43.

Mutation update for the SATB2 gene.

Zarate YA, Bosanko KA, Caffrey AR, Bernstein JA, Martin DM, Williams MS, Berry-Kravis EM, Mark PR, Manning MA, Bhambhani V, Vargas M, Seeley AH, Estrada-Veras JI, van Dooren MF, Schwab M, Vanderver A, Melis D, Alsadah A, Sadler L, Van Esch H, Callewaert B, Oostra A, Maclean J, Dentici ML, Orlando V, Lipson M, Sparagana SP, Maarup TJ, Alsters SI, Brautbar A, Kovitch E, Naidu S, Lees M, Smith DM, Turner L, Raggio V, Spangenberg L, Garcia-Miñaúr S, Roeder ER, Littlejohn RO, Grange D, Pfotenhauer J, Jones MC, Balasubramanian M, Martinez-Monseny A, Blok LS, Gavrilova R, Fish JL.

Hum Mutat. 2019 Aug;40(8):1013-1029. doi: 10.1002/humu.23771. Epub 2019 Jun 18.

PMID:
31021519
44.

Assessment of concomitant non-oncologic medication in patients with surgically treated renal cell carcinoma: impact on prognosis, cell-cycle progression and proliferation.

Neumann E, Klaiber P, Freitag K, Schwab M, Schaeffeler E, Hennenlotter J, Fend F, Kruck S, Scharpf M, Stenzl A, Bedke J, Rausch S.

J Cancer Res Clin Oncol. 2019 Jul;145(7):1835-1843. doi: 10.1007/s00432-019-02914-2. Epub 2019 Apr 22.

PMID:
31006846
45.

Publisher Correction: NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies.

Fledrich R, Akkermann D, Schütza V, Abdelaal TA, Hermes D, Schäffner E, Soto-Bernardini MC, Götze T, Klink A, Kusch K, Krueger M, Kungl T, Frydrychowicz C, Möbius W, Brück W, Mueller WC, Bechmann I, Sereda MW, Schwab MH, Nave KA, Stassart RM.

Nat Commun. 2019 Apr 16;10(1):1840. doi: 10.1038/s41467-019-09886-4.

46.

Signal Disruption Leads to Changes in Bacterial Community Population.

Schwab M, Bergonzi C, Sakkos J, Staley C, Zhang Q, Sadowsky MJ, Aksan A, Elias M.

Front Microbiol. 2019 Mar 29;10:611. doi: 10.3389/fmicb.2019.00611. eCollection 2019.

47.

The Spinal Transcriptome after Cortical Stroke: In Search of Molecular Factors Regulating Spontaneous Recovery in the Spinal Cord.

Kaiser J, Maibach M, Salpeter I, Hagenbuch N, de Souza VBC, Robinson MD, Schwab ME.

J Neurosci. 2019 Jun 12;39(24):4714-4726. doi: 10.1523/JNEUROSCI.2571-18.2019. Epub 2019 Apr 8.

48.

Correction to: Investigation of Neuregulin-1 and Glial Cell-Derived Neurotrophic Factor in Rodent Astrocytes and Microglia.

Kronenberg J, Merkel L, Heckers S, Gudi V, Schwab MH, Stangel M.

J Mol Neurosci. 2019 Jun;68(2):318. doi: 10.1007/s12031-019-01315-x.

PMID:
30953282
49.

NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies.

Fledrich R, Akkermann D, Schütza V, Abdelaal TA, Hermes D, Schäffner E, Soto-Bernardini MC, Götze T, Klink A, Kusch K, Krueger M, Kungl T, Frydrychowicz C, Möbius W, Brück W, Mueller WC, Bechmann I, Sereda MW, Schwab MH, Nave KA, Stassart RM.

Nat Commun. 2019 Apr 1;10(1):1467. doi: 10.1038/s41467-019-09385-6. Erratum in: Nat Commun. 2019 Apr 16;10(1):1840.

50.

Localization and dynamic changes of neuregulin-1 at C-type synaptic boutons in association with motor neuron injury and repair.

Salvany S, Casanovas A, Tarabal O, Piedrafita L, Hernández S, Santafé M, Soto-Bernardini MC, Calderó J, Schwab MH, Esquerda JE.

FASEB J. 2019 Jul;33(7):7833-7851. doi: 10.1096/fj.201802329R. Epub 2019 Mar 26.

PMID:
30912977

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