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Items: 1 to 50 of 1535

1.

Variability and heritability of thiamine pharmacokinetics with focus on OCT1 effects on membrane transport and pharmacokinetics in humans.

Jensen O, Matthaei J, Blome F, Schwab M, Tzvetkov MV, Brockmöller J.

Clin Pharmacol Ther. 2019 Oct 8. doi: 10.1002/cpt.1666. [Epub ahead of print]

PMID:
31593619
2.

The Influences of Adherence to Tamoxifen and CYP2D6 Pharmacogenetics on Plasma Concentrations of the Active Metabolite (Z)-Endoxifen in Breast Cancer.

Nardin JM, Schroth W, Almeida TA, Mürdter T, Picolotto S, Vendramini ECL, Hoppe R, Kogin JP, Miqueleto D, de Moraes SDR, Schwab M, Pecoits-Filho RF, Brauch H, Casali-da-Rocha JC.

Clin Transl Sci. 2019 Oct 1. doi: 10.1111/cts.12707. [Epub ahead of print]

PMID:
31573754
3.

Radiosensitization of HSF-1 Knockdown Lung Cancer Cells by Low Concentrations of Hsp90 Inhibitor NVP-AUY922.

Kühnel A, Schilling D, Combs SE, Haller B, Schwab M, Multhoff G.

Cells. 2019 Sep 28;8(10). pii: E1166. doi: 10.3390/cells8101166.

4.

Enhancing rehabilitation and functional recovery after brain and spinal cord trauma with electrical neuromodulation.

Hofer AS, Schwab ME.

Curr Opin Neurol. 2019 Sep 24. doi: 10.1097/WCO.0000000000000750. [Epub ahead of print]

PMID:
31567546
5.

Platelet surface expression of cyclophilin A is associated with increased mortality in patients with symptomatic coronary artery disease.

Rath D, von Ungern-Sternberg S, Heinzmann D, Sigle M, Monzien M, Horstmann K, Schaeffeler E, Winter S, Müller K, Groga-Bada P, Zdanyte M, Borst O, Zernecke A, Gawaz M, Martus P, Schwab M, Geisler T, Seizer P.

J Thromb Haemost. 2019 Sep 13. doi: 10.1111/jth.14635. [Epub ahead of print]

PMID:
31519036
6.

Pharmacogenomic Polygenic Response Score Predicts Ischemic Events and Cardiovascular Mortality in Clopidogrel-Treated Patients.

Lewis JP, Backman JD, Reny JL, Bergmeijer TO, Mitchell BD, Ritchie MD, Déry JP, Pakyz RE, Gong L, Ryan K, Kim EY, Aradi D, Fernandez-Cadenas I, Lee MTM, Whaley RM, Montaner J, Gensini GF, Cleator JH, Chang K, Holmvang L, Hochholzer W, Roden DM, Winter S, Altman R, Alexopoulos D, Kim HS, Gawaz M, Bliden K, Valgimigli M, Marcucci R, Campo G, Schaeffeler E, Dridi NP, Wen MS, Shin JG, Fontana P, Giusti B, Geisler T, Kubo M, Trenk D, Siller-Matula JM, Ten Berg JM, Gurbel PA, Schwab M, Klein TE, Shuldiner AR.

Eur Heart J Cardiovasc Pharmacother. 2019 Sep 3. pii: pvz045. doi: 10.1093/ehjcvp/pvz045. [Epub ahead of print]

PMID:
31504375
7.

Maternal psychosocial stress during early gestation impairs fetal structural brain development in sheep.

Hermes M, Antonow-Schlorke I, Hollstein D, Kuehnel S, Rakers F, Frauendorf V, Dreiling M, Rupprecht S, Schubert H, Witte OW, Schwab M.

Stress. 2019 Aug 30:1-10. doi: 10.1080/10253890.2019.1652266. [Epub ahead of print]

PMID:
31469022
8.

Combined with anti-Nogo-A antibody treatment, BDNF did not compensate the extra deleterious motor effect caused by large size cervical cord hemisection in adult macaques.

Beaud ML, Rouiller EM, Bloch J, Mir A, Schwab ME, Schmidlin E.

CNS Neurosci Ther. 2019 Aug 16. doi: 10.1111/cns.13213. [Epub ahead of print]

PMID:
31418518
9.

Late-life brain perfusion after prenatal famine exposure.

de Rooij SR, Mutsaerts HJMM, Petr J, Asllani I, Caan MWA, Groot P, Nederveen AJ, Schwab M, Roseboom TJ.

Neurobiol Aging. 2019 Jul 8;82:1-9. doi: 10.1016/j.neurobiolaging.2019.06.012. [Epub ahead of print]

PMID:
31376728
10.

Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1.

Chen M, Neul C, Schaeffeler E, Frisch F, Winter S, Schwab M, Koepsell H, Hu S, Laufer S, Baker SD, Sparreboom A, Nies AT.

Clin Pharmacol Ther. 2019 Jul 27. doi: 10.1002/cpt.1588. [Epub ahead of print]

PMID:
31350763
11.

Identification of novel agonists by high-throughput screening and molecular modelling of human constitutive androstane receptor isoform 3.

Keminer O, Windshügel B, Essmann F, Lee SML, Schiergens TS, Schwab M, Burk O.

Arch Toxicol. 2019 Aug;93(8):2247-2264. doi: 10.1007/s00204-019-02495-6. Epub 2019 Jul 16.

PMID:
31312845
12.

Refueling the Ischemic CNS: Guidance Molecules for Vascular Repair.

Rust R, Grönnert L, Weber RZ, Mulders G, Schwab ME.

Trends Neurosci. 2019 Sep;42(9):644-656. doi: 10.1016/j.tins.2019.05.006. Epub 2019 Jul 5. Review.

PMID:
31285047
13.

Pancreatic stenting to prevent post-ERCP pancreatitis: a randomized multicenter trial.

Phillip V, Pukitis A, Epstein A, Hapfelmeier A, Haf D, Schwab M, Demir IE, Rosendahl J, Hoffmeister A, Schmid RM, Weber A, Algül H.

Endosc Int Open. 2019 Jul;7(7):E860-E868. doi: 10.1055/a-0886-6384. Epub 2019 Jul 3.

14.

High-Resolution PET Cisternography With 64Cu-DOTA for CSF Leak Detection.

Freesmeyer M, Schwab M, Besteher B, Gröber S, Waschke A, Drescher R.

Clin Nucl Med. 2019 Sep;44(9):735-737. doi: 10.1097/RLU.0000000000002695.

PMID:
31274554
15.

Pharmacogenomics education in medical and pharmacy schools: conclusions of a global survey.

Karas Kuželički N, Prodan Žitnik I, Gurwitz D, Llerena A, Cascorbi I, Siest S, Simmaco M, Ansari M, Pazzagli M, Di Resta C, Brandslund I, Schwab M, Vermeersch P, Lunshof JE, Dedoussis G, Flordellis CS, Fuhr U, Stingl JC, van Schaik RH, Manolopoulos VG, Marc J; Pharmacogenomics Education Working Group (PGxEWG); European Society of Pharmacogenomics and Personalized Therapy (ESPT).

Pharmacogenomics. 2019 Jun;20(9):643-657. doi: 10.2217/pgs-2019-0009.

16.

A Clinical Drug-Drug Interaction Study Assessing a Novel Drug Transporter Phenotyping Cocktail With Adefovir, Sitagliptin, Metformin, Pitavastatin, and Digoxin.

Trueck C, Hsin CH, Scherf-Clavel O, Schaeffeler E, Lenssen R, Gazzaz M, Gersie M, Taubert M, Quasdorff M, Schwab M, Kinzig M, Sörgel F, Stoffel MS, Fuhr U.

Clin Pharmacol Ther. 2019 Jun 27. doi: 10.1002/cpt.1564. [Epub ahead of print]

PMID:
31247117
17.

Nogo-A targeted therapy promotes vascular repair and functional recovery following stroke.

Rust R, Grönnert L, Gantner C, Enzler A, Mulders G, Weber RZ, Siewert A, Limasale YDP, Meinhardt A, Maurer MA, Sartori AM, Hofer AS, Werner C, Schwab ME.

Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14270-14279. doi: 10.1073/pnas.1905309116. Epub 2019 Jun 24.

PMID:
31235580
18.

Corrigendum: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy.

Belin S, Ornaghi F, Shackleford G, Wang J, Scapin C, Lopez-Anido C, Silvestri N, Robertson N, Williamson C, Ishii A, Taveggia C, Svaren J, Bansal R, Schwab MH, Nave K, Fratta P, D'Antonio M, Poitelon Y, Feltri ML, Wrabetz L.

Hum Mol Genet. 2019 Jul 1;28(13):2282. doi: 10.1093/hmg/ddz037. No abstract available.

19.

The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes.

Pattschull G, Walz S, Gründl M, Schwab M, Rühl E, Baluapuri A, Cindric-Vranesic A, Kneitz S, Wolf E, Ade CP, Rosenwald A, von Eyss B, Gaubatz S.

Cell Rep. 2019 Jun 18;27(12):3533-3546.e7. doi: 10.1016/j.celrep.2019.05.071.

20.

Tamoxifen Pharmacogenetics and Metabolism: The Same Is Not the Same.

Brauch H, Schroth W, Mürdter T, Schwab M.

J Clin Oncol. 2019 Aug 1;37(22):1981-1982. doi: 10.1200/JCO.19.00507. Epub 2019 Jun 18. No abstract available.

PMID:
31211600
21.

Intranasal Administration of Mesenchymal Stem Cells Ameliorates the Abnormal Dopamine Transmission System and Inflammatory Reaction in the R6/2 Mouse Model of Huntington Disease.

Yu-Taeger L, Stricker-Shaver J, Arnold K, Bambynek-Dziuk P, Novati A, Singer E, Lourhmati A, Fabian C, Magg J, Riess O, Schwab M, Stolzing A, Danielyan L, Nguyen HHP.

Cells. 2019 Jun 15;8(6). pii: E595. doi: 10.3390/cells8060595.

22.

Corticotectal Projections From the Premotor or Primary Motor Cortex After Cortical Lesion or Parkinsonian Symptoms in Adult Macaque Monkeys: A Pilot Tracing Study.

Fregosi M, Contestabile A, Badoud S, Borgognon S, Cottet J, Brunet JF, Bloch J, Schwab ME, Rouiller EM.

Front Neuroanat. 2019 May 22;13:50. doi: 10.3389/fnana.2019.00050. eCollection 2019.

23.

Clinical Trial: CYP2D6 Related Dose Escalation of Tamoxifen in Breast Cancer Patients With Iranian Ethnic Background Resulted in Increased Concentrations of Tamoxifen and Its Metabolites.

Khalaj Z, Baratieh Z, Nikpour P, Schwab M, Schaeffeler E, Mokarian F, Khanahmad H, Salehi R, Mürdter TE, Salehi M.

Front Pharmacol. 2019 May 24;10:530. doi: 10.3389/fphar.2019.00530. eCollection 2019.

24.

Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole.

Türk D, Hanke N, Wolf S, Frechen S, Eissing T, Wendl T, Schwab M, Lehr T.

Clin Pharmacokinet. 2019 May 25. doi: 10.1007/s40262-019-00777-x. [Epub ahead of print]

PMID:
31129789
25.

Evaluation of biological and enzymatic quorum quencher coating additives to reduce biocorrosion of steel.

Huang S, Bergonzi C, Schwab M, Elias M, Hicks RE.

PLoS One. 2019 May 16;14(5):e0217059. doi: 10.1371/journal.pone.0217059. eCollection 2019.

26.

Association Between Systemic Inflammation, Carotid Arteriosclerosis, and Autonomic Dysfunction.

Rupprecht S, Finn S, Hoyer D, Guenther A, Witte OW, Schultze T, Schwab M.

Transl Stroke Res. 2019 May 16. doi: 10.1007/s12975-019-00706-x. [Epub ahead of print]

PMID:
31093927
27.

A smart peek: Processing of rapid visual displays is disturbed in newly diagnosed, cognitively intact MS patients and refers to cognitive performance and disease progression in late stages.

Fischer M, Köhler W, Faiss JH, Hoffmann F, Kunkel A, Sailer M, Schwab M, Zettl UK, Bublak P; HIPPOCOMS Study Group.

J Neurol Sci. 2019 Jun 15;401:118-124. doi: 10.1016/j.jns.2019.04.031. Epub 2019 Apr 23.

PMID:
31075683
28.

RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas.

Wirthschaft P, Bode J, Soni H, Dietrich F, Krüwel T, Fischer B, Knobbe-Thomsen CB, Rossetti G, Hentschel A, Mack N, Schönig K, Breckwoldt MO, Schmandke A, Pusch S, Medenbach J, Bendszus M, Schwab ME, von Deimling A, Kool M, Herold-Mende C, Reifenberger G, Ahrends R, Tews B.

Acta Neuropathol. 2019 Aug;138(2):275-293. doi: 10.1007/s00401-019-02021-z. Epub 2019 May 6.

29.

Development of the PGx-Passport: A Panel of Actionable Germline Genetic Variants for Pre-Emptive Pharmacogenetic Testing.

van der Wouden CH, van Rhenen MH, Jama WOM, Ingelman-Sundberg M, Lauschke VM, Konta L, Schwab M, Swen JJ, Guchelaar HJ.

Clin Pharmacol Ther. 2019 Oct;106(4):866-873. doi: 10.1002/cpt.1489. Epub 2019 Jun 12.

30.

Measuring broader wellbeing in mental health services: validity of the German language OxCAP-MH capability instrument.

Łaszewska A, Schwab M, Leutner E, Oberrauter M, Spiel G, Simon J.

Qual Life Res. 2019 Aug;28(8):2311-2323. doi: 10.1007/s11136-019-02187-9. Epub 2019 Apr 27.

31.

Mutation update for the SATB2 gene.

Zarate YA, Bosanko KA, Caffrey AR, Bernstein JA, Martin DM, Williams MS, Berry-Kravis EM, Mark PR, Manning MA, Bhambhani V, Vargas M, Seeley AH, Estrada-Veras JI, van Dooren MF, Schwab M, Vanderver A, Melis D, Alsadah A, Sadler L, Van Esch H, Callewaert B, Oostra A, Maclean J, Dentici ML, Orlando V, Lipson M, Sparagana SP, Maarup TJ, Alsters SI, Brautbar A, Kovitch E, Naidu S, Lees M, Smith DM, Turner L, Raggio V, Spangenberg L, Garcia-Miñaúr S, Roeder ER, Littlejohn RO, Grange D, Pfotenhauer J, Jones MC, Balasubramanian M, Martinez-Monseny A, Blok LS, Gavrilova R, Fish JL.

Hum Mutat. 2019 Aug;40(8):1013-1029. doi: 10.1002/humu.23771. Epub 2019 Jun 18.

PMID:
31021519
32.

Assessment of concomitant non-oncologic medication in patients with surgically treated renal cell carcinoma: impact on prognosis, cell-cycle progression and proliferation.

Neumann E, Klaiber P, Freitag K, Schwab M, Schaeffeler E, Hennenlotter J, Fend F, Kruck S, Scharpf M, Stenzl A, Bedke J, Rausch S.

J Cancer Res Clin Oncol. 2019 Jul;145(7):1835-1843. doi: 10.1007/s00432-019-02914-2. Epub 2019 Apr 22.

PMID:
31006846
33.

Publisher Correction: NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies.

Fledrich R, Akkermann D, Schütza V, Abdelaal TA, Hermes D, Schäffner E, Soto-Bernardini MC, Götze T, Klink A, Kusch K, Krueger M, Kungl T, Frydrychowicz C, Möbius W, Brück W, Mueller WC, Bechmann I, Sereda MW, Schwab MH, Nave KA, Stassart RM.

Nat Commun. 2019 Apr 16;10(1):1840. doi: 10.1038/s41467-019-09886-4.

34.

Signal Disruption Leads to Changes in Bacterial Community Population.

Schwab M, Bergonzi C, Sakkos J, Staley C, Zhang Q, Sadowsky MJ, Aksan A, Elias M.

Front Microbiol. 2019 Mar 29;10:611. doi: 10.3389/fmicb.2019.00611. eCollection 2019.

35.

The Spinal Transcriptome after Cortical Stroke: In Search of Molecular Factors Regulating Spontaneous Recovery in the Spinal Cord.

Kaiser J, Maibach M, Salpeter I, Hagenbuch N, de Souza VBC, Robinson MD, Schwab ME.

J Neurosci. 2019 Jun 12;39(24):4714-4726. doi: 10.1523/JNEUROSCI.2571-18.2019. Epub 2019 Apr 8.

36.

Correction to: Investigation of Neuregulin-1 and Glial Cell-Derived Neurotrophic Factor in Rodent Astrocytes and Microglia.

Kronenberg J, Merkel L, Heckers S, Gudi V, Schwab MH, Stangel M.

J Mol Neurosci. 2019 Jun;68(2):318. doi: 10.1007/s12031-019-01315-x.

PMID:
30953282
37.

NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies.

Fledrich R, Akkermann D, Schütza V, Abdelaal TA, Hermes D, Schäffner E, Soto-Bernardini MC, Götze T, Klink A, Kusch K, Krueger M, Kungl T, Frydrychowicz C, Möbius W, Brück W, Mueller WC, Bechmann I, Sereda MW, Schwab MH, Nave KA, Stassart RM.

Nat Commun. 2019 Apr 1;10(1):1467. doi: 10.1038/s41467-019-09385-6. Erratum in: Nat Commun. 2019 Apr 16;10(1):1840.

38.

Localization and dynamic changes of neuregulin-1 at C-type synaptic boutons in association with motor neuron injury and repair.

Salvany S, Casanovas A, Tarabal O, Piedrafita L, Hernández S, Santafé M, Soto-Bernardini MC, Calderó J, Schwab MH, Esquerda JE.

FASEB J. 2019 Jul;33(7):7833-7851. doi: 10.1096/fj.201802329R. Epub 2019 Mar 26.

PMID:
30912977
39.

Anti-Nogo-A Antibodies As a Potential Causal Therapy for Lower Urinary Tract Dysfunction after Spinal Cord Injury.

Schneider MP, Sartori AM, Ineichen BV, Moors S, Engmann AK, Hofer AS, Weinmann O, Kessler TM, Schwab ME.

J Neurosci. 2019 May 22;39(21):4066-4076. doi: 10.1523/JNEUROSCI.3155-18.2019. Epub 2019 Mar 22.

PMID:
30902870
40.

Female Adnexal Tumour of Probable Wolffian Origin (FATWO): Review of the Literature.

Hübner TB, Schwab M, Hartmann E, Mayr D, Thurner A, Bley T, Wöckel A, Herr D.

Geburtshilfe Frauenheilkd. 2019 Mar;79(3):281-285. doi: 10.1055/a-0746-8985. Epub 2019 Mar 12.

41.

The Structural Determinants Accounting for the Broad Substrate Specificity of the Quorum Quenching Lactonase GcL.

Bergonzi C, Schwab M, Naik T, Elias M.

Chembiochem. 2019 Jul 15;20(14):1848-1855. doi: 10.1002/cbic.201900024. Epub 2019 May 22.

PMID:
30864300
42.

To rout or snort in the sleepe: a detailed medical description of sleep disordered breathing and its consequences by Georg Grau in 1688.

Rupprecht S, Schönefeld D, Kroegel N, Witte OW, Schwab M, Paditz E.

Eur Respir J. 2019 May 9;53(5). pii: 1801799. doi: 10.1183/13993003.01799-2018. Print 2019 May. No abstract available.

PMID:
30846473
43.

A Revised View on Growth and Remodeling in the Retinal Vasculature.

Rust R, Grönnert L, Dogançay B, Schwab ME.

Sci Rep. 2019 Mar 1;9(1):3263. doi: 10.1038/s41598-019-40135-2.

44.

Intranasal Losartan Decreases Perivascular Beta Amyloid, Inflammation, and the Decline of Neurogenesis in Hypertensive Rats.

Drews HJ, Yenkoyan K, Lourhmati A, Buadze M, Kabisch D, Verleysdonk S, Petschak S, Beer-Hammer S, Davtyan T, Frey WH 2nd, Gleiter CH, Schwab M, Danielyan L.

Neurotherapeutics. 2019 Jul;16(3):725-740. doi: 10.1007/s13311-019-00723-6.

PMID:
30796737
45.

Ten years of Genome Medicine.

Auffray C, Griffin JL, Khoury MJ, Lupski JR, Schwab M.

Genome Med. 2019 Feb 15;11(1):7. doi: 10.1186/s13073-019-0618-x. No abstract available.

46.

A New Panel-Based Next-Generation Sequencing Method for ADME Genes Reveals Novel Associations of Common and Rare Variants With Expression in a Human Liver Cohort.

Klein K, Tremmel R, Winter S, Fehr S, Battke F, Scheurenbrand T, Schaeffeler E, Biskup S, Schwab M, Zanger UM.

Front Genet. 2019 Jan 31;10:7. doi: 10.3389/fgene.2019.00007. eCollection 2019.

47.

Physiologically-Based Pharmacokinetic Models for CYP1A2 Drug-Drug Interaction Prediction: A Modeling Network of Fluvoxamine, Theophylline, Caffeine, Rifampicin, and Midazolam.

Britz H, Hanke N, Volz AK, Spigset O, Schwab M, Eissing T, Wendl T, Frechen S, Lehr T.

CPT Pharmacometrics Syst Pharmacol. 2019 May;8(5):296-307. doi: 10.1002/psp4.12397. Epub 2019 Mar 13.

48.

Molecular signature of human bone marrow-derived mesenchymal stromal cell subsets.

Kuçi S, Kuçi Z, Schäfer R, Spohn G, Winter S, Schwab M, Salzmann-Manrique E, Klingebiel T, Bader P.

Sci Rep. 2019 Feb 11;9(1):1774. doi: 10.1038/s41598-019-38517-7.

49.

Impact of NUDT15 genetics on severe thiopurine-related hematotoxicity in patients with European ancestry.

Schaeffeler E, Jaeger SU, Klumpp V, Yang JJ, Igel S, Hinze L, Stanulla M, Schwab M.

Genet Med. 2019 Sep;21(9):2145-2150. doi: 10.1038/s41436-019-0448-7. Epub 2019 Feb 7.

50.

NeuroD2 controls inhibitory circuit formation in the molecular layer of the cerebellum.

Pieper A, Rudolph S, Wieser GL, Götze T, Mießner H, Yonemasu T, Yan K, Tzvetanova I, Castillo BD, Bode U, Bormuth I, Wadiche JI, Schwab MH, Goebbels S.

Sci Rep. 2019 Feb 5;9(1):1448. doi: 10.1038/s41598-018-37850-7.

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