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Best matches for Schwäble J[au]:

Gene therapy with adeno-associated virus vector 5-human factor IX in adults with hemophilia B. Miesbach W et al. Blood. (2018)

The molecular pathogenesis of acute myeloid leukemia. Steffen B et al. Crit Rev Oncol Hematol. (2005)

CD133-targeted gene transfer into long-term repopulating hematopoietic stem cells. Brendel C et al. Mol Ther. (2015)

Search results

Items: 30

1.

High Efficiency Gene Correction in Hematopoietic Cells by Donor-Template-Free CRISPR/Cas9 Genome Editing.

Sürün D, Schwäble J, Tomasovic A, Ehling R, Stein S, Kurrle N, von Melchner H, Schnütgen F.

Mol Ther Nucleic Acids. 2018 Mar 2;10:1-8. doi: 10.1016/j.omtn.2017.11.001. Epub 2017 Nov 10.

2.

Gene therapy with adeno-associated virus vector 5-human factor IX in adults with hemophilia B.

Miesbach W, Meijer K, Coppens M, Kampmann P, Klamroth R, Schutgens R, Tangelder M, Castaman G, Schwäble J, Bonig H, Seifried E, Cattaneo F, Meyer C, Leebeek FWG.

Blood. 2018 Mar 1;131(9):1022-1031. doi: 10.1182/blood-2017-09-804419. Epub 2017 Dec 15.

3.

Hyperinflammation in patients with chronic granulomatous disease leads to impairment of hematopoietic stem cell functions.

Weisser M, Demel UM, Stein S, Chen-Wichmann L, Touzot F, Santilli G, Sujer S, Brendel C, Siler U, Cavazzana M, Thrasher AJ, Reichenbach J, Essers MAG, Schwäble J, Grez M.

J Allergy Clin Immunol. 2016 Jul;138(1):219-228.e9. doi: 10.1016/j.jaci.2015.11.028. Epub 2016 Feb 4.

PMID:
26853280
4.

Successful Combination of Sequential Gene Therapy and Rescue Allo-HSCT in Two Children with X-CGD - Importance of Timing.

Siler U, Paruzynski A, Holtgreve-Grez H, Kuzmenko E, Koehl U, Renner ED, Alhan C, de Loosdrecht AA, Schwäble J, Pfluger T, Tchinda J, Schmugge M, Jauch A, Naundorf S, Kühlcke K, Notheis G, Güngor T, Kalle CV, Schmidt M, Grez M, Seger R, Reichenbach J.

Curr Gene Ther. 2015;15(4):416-27.

PMID:
25981636
5.

CD133-targeted gene transfer into long-term repopulating hematopoietic stem cells.

Brendel C, Goebel B, Daniela A, Brugman M, Kneissl S, Schwäble J, Kaufmann KB, Müller-Kuller U, Kunkel H, Chen-Wichmann L, Abel T, Serve H, Bystrykh L, Buchholz CJ, Grez M.

Mol Ther. 2015 Jan;23(1):63-70. doi: 10.1038/mt.2014.173. Epub 2014 Sep 5. Erratum in: Mol Ther. 2015 Apr;23(4):790.

6.

From bench to bedside: preclinical evaluation of a self-inactivating gammaretroviral vector for the gene therapy of X-linked chronic granulomatous disease.

Stein S, Scholz S, Schwäble J, Sadat MA, Modlich U, Schultze-Strasser S, Diaz M, Chen-Wichmann L, Müller-Kuller U, Brendel C, Fronza R, Kaufmann KB, Naundorf S, Pech NK, Travers JB, Matute JD, Presson RG Jr, Sandusky GE, Kunkel H, Rudolf E, Dillmann A, von Kalle C, Kühlcke K, Baum C, Schambach A, Dinauer MC, Schmidt M, Grez M.

Hum Gene Ther Clin Dev. 2013 Jun;24(2):86-98. doi: 10.1089/humc.2013.019.

7.

Alpharetroviral vector-mediated gene therapy for X-CGD: functional correction and lack of aberrant splicing.

Kaufmann KB, Brendel C, Suerth JD, Mueller-Kuller U, Chen-Wichmann L, Schwäble J, Pahujani S, Kunkel H, Schambach A, Baum C, Grez M.

Mol Ther. 2013 Mar;21(3):648-61. doi: 10.1038/mt.2012.249. Epub 2012 Dec 4.

8.

[Gene therapy for septic granulomatosis: risks and opportunities. The road to successful treatment of congenital immunodeficiency].

Schwäble J, Schultze-Strasser S, Stein S, Grez M.

Pharm Unserer Zeit. 2011 May;40(3):264-71. doi: 10.1002/pauz.201100422. Review. German. No abstract available.

PMID:
21698616
9.

Gene therapy of chronic granulomatous disease: the engraftment dilemma.

Grez M, Reichenbach J, Schwäble J, Seger R, Dinauer MC, Thrasher AJ.

Mol Ther. 2011 Jan;19(1):28-35. doi: 10.1038/mt.2010.232. Epub 2010 Nov 2. Review.

10.

Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease.

Stein S, Ott MG, Schultze-Strasser S, Jauch A, Burwinkel B, Kinner A, Schmidt M, Krämer A, Schwäble J, Glimm H, Koehl U, Preiss C, Ball C, Martin H, Göhring G, Schwarzwaelder K, Hofmann WK, Karakaya K, Tchatchou S, Yang R, Reinecke P, Kühlcke K, Schlegelberger B, Thrasher AJ, Hoelzer D, Seger R, von Kalle C, Grez M.

Nat Med. 2010 Feb;16(2):198-204. doi: 10.1038/nm.2088. Epub 2010 Jan 24.

PMID:
20098431
11.

Flt3-dependent transformation by inactivating c-Cbl mutations in AML.

Sargin B, Choudhary C, Crosetto N, Schmidt MHH, Grundler R, Rensinghoff M, Thiessen C, Tickenbrock L, Schwäble J, Brandts C, August B, Koschmieder S, Bandi SR, Duyster J, Berdel WE, Müller-Tidow C, Dikic I, Serve H.

Blood. 2007 Aug 1;110(3):1004-12. Epub 2007 Apr 19.

PMID:
17446348
12.

Activation mechanisms of STAT5 by oncogenic Flt3-ITD.

Choudhary C, Brandts C, Schwable J, Tickenbrock L, Sargin B, Ueker A, Böhmer FD, Berdel WE, Müller-Tidow C, Serve H.

Blood. 2007 Jul 1;110(1):370-4. Epub 2007 Mar 13.

PMID:
17356133
13.

Growth inhibition and induction of apoptosis in acute myeloid leukemia cells by new indolinone derivatives targeting fibroblast growth factor, platelet-derived growth factor, and vascular endothelial growth factor receptors.

Kulimova E, Oelmann E, Bisping G, Kienast J, Mesters RM, Schwäble J, Hilberg F, Roth GJ, Munzert G, Stefanic M, Steffen B, Brandts C, Müller-Tidow C, Kolkmeyer A, Büchner T, Serve H, Berdel WE.

Mol Cancer Ther. 2006 Dec;5(12):3105-12.

14.

Wnt signaling regulates transendothelial migration of monocytes.

Tickenbrock L, Schwäble J, Strey A, Sargin B, Hehn S, Baas M, Choudhary C, Gerke V, Berdel WE, Müller-Tidow C, Serve H.

J Leukoc Biol. 2006 Jun;79(6):1306-13. Epub 2006 Mar 24.

PMID:
16565323
15.

Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation.

Brandts CH, Sargin B, Rode M, Biermann C, Lindtner B, Schwäble J, Buerger H, Müller-Tidow C, Choudhary C, McMahon M, Berdel WE, Serve H.

Cancer Res. 2005 Nov 1;65(21):9643-50.

16.

The molecular pathogenesis of acute myeloid leukemia.

Steffen B, Müller-Tidow C, Schwäble J, Berdel WE, Serve H.

Crit Rev Oncol Hematol. 2005 Nov;56(2):195-221. Epub 2005 Oct 19. Review.

PMID:
16236521
17.

AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations.

Choudhary C, Schwäble J, Brandts C, Tickenbrock L, Sargin B, Kindler T, Fischer T, Berdel WE, Müller-Tidow C, Serve H.

Blood. 2005 Jul 1;106(1):265-73. Epub 2005 Mar 15.

PMID:
15769897
18.

Identification of metastasis-associated receptor tyrosine kinases in non-small cell lung cancer.

Müller-Tidow C, Diederichs S, Bulk E, Pohle T, Steffen B, Schwäble J, Plewka S, Thomas M, Metzger R, Schneider PM, Brandts CH, Berdel WE, Serve H.

Cancer Res. 2005 Mar 1;65(5):1778-82.

19.

Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction.

Tickenbrock L, Schwäble J, Wiedehage M, Steffen B, Sargin B, Choudhary C, Brandts C, Berdel WE, Müller-Tidow C, Serve H.

Blood. 2005 May 1;105(9):3699-706. Epub 2005 Jan 13.

PMID:
15650056
20.

RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation.

Schwäble J, Choudhary C, Thiede C, Tickenbrock L, Sargin B, Steur C, Rehage M, Rudat A, Brandts C, Berdel WE, Müller-Tidow C, Serve H.

Blood. 2005 Mar 1;105(5):2107-14. Epub 2004 Nov 9.

PMID:
15536149
21.

The serine-threonine kinase MNK1 is post-translationally stabilized by PML-RARalpha and regulates differentiation of hematopoietic cells.

Worch J, Tickenbrock L, Schwäble J, Steffen B, Cauvet T, Mlody B, Buerger H, Koeffler HP, Berdel WE, Serve H, Müller-Tidow C.

Oncogene. 2004 Dec 9;23(57):9162-72.

PMID:
15516979
22.

Flt3 receptor tyrosine kinase as a drug target in leukemia.

Schmidt-Arras D, Schwäble J, Böhmer FD, Serve H.

Curr Pharm Des. 2004;10(16):1867-83. Review.

PMID:
15180525
23.

High-throughput analysis of genome-wide receptor tyrosine kinase expression in human cancers identifies potential novel drug targets.

Müller-Tidow C, Schwäble J, Steffen B, Tidow N, Brandt B, Becker K, Schulze-Bahr E, Halfter H, Vogt U, Metzger R, Schneider PM, Büchner T, Brandts C, Berdel WE, Serve H.

Clin Cancer Res. 2004 Feb 15;10(4):1241-9.

24.

Expression of the p14ARF tumor suppressor predicts survival in acute myeloid leukemia.

Müller-Tidow C, Metzelder SK, Buerger H, Packeisen J, Ganser A, Heil G, Kügler K, Adigüzel G, Schwäble J, Steffen B, Ludwig WD, Heinecke A, Büchner T, Berdel WE, Serve H.

Leukemia. 2004 Apr;18(4):720-6.

PMID:
14973498
25.

Oncogenic receptor tyrosine kinase in leukemia.

Mizuki M, Ueda S, Matsumura I, Ishiko J, Schwäble J, Serve H, Kanakura Y.

Cell Mol Biol (Noisy-le-grand). 2003 Sep;49(6):907-22. Review.

PMID:
14656048
26.

Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations.

Mizuki M, Schwable J, Steur C, Choudhary C, Agrawal S, Sargin B, Steffen B, Matsumura I, Kanakura Y, Böhmer FD, Müller-Tidow C, Berdel WE, Serve H.

Blood. 2003 Apr 15;101(8):3164-73. Epub 2002 Dec 5.

PMID:
12468433
27.

[Mutations of growth factor receptor Flt3 in acute myeloid leukemia: transformation of myeloid cells by Ras-dependent and Ras-independent mechanisms].

Müller-Tidow C, Steur C, Mizuki M, Schwäble J, Brandts C, Berdel WE, Serve H.

Dtsch Med Wochenschr. 2002 Oct 18;127(42):2195-200. German.

PMID:
12397548
28.

Bis(1H-2-indolyl)-1-methanones as inhibitors of the hematopoietic tyrosine kinase Flt3.

Teller S, Krämer D, Böhmer SA, Tse KF, Small D, Mahboobi S, Wallrapp C, Beckers T, Kratz-Albers K, Schwäble J, Serve H, Böhmer FD.

Leukemia. 2002 Aug;16(8):1528-34.

29.

Neuroblastoma: induction of differentiation (Part I). Basical science in pediatric surgery.

Girgert R, Schweizer P, Schwäble J.

Eur J Pediatr Surg. 2000 Apr;10(2):79-82.

PMID:
10877072
30.

Detection of rare target genes on northern blots with cDNA probes labeled by reverse transcriptase-polymerase chain reaction with simultaneous digoxigenin incorporation.

Schwäble J, Wittrock J, Schweizer P, Girgert R.

Anal Biochem. 1998 Aug 15;262(1):77-9. No abstract available.

PMID:
9735150

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