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Items: 1 to 50 of 68

1.

Closing the DNA replication cycle: from simple circular molecules to supercoiled and knotted DNA catenanes.

Schvartzman JB, Hernández P, Krimer DB, Dorier J, Stasiak A.

Nucleic Acids Res. 2019 Jul 5. pii: gkz586. doi: 10.1093/nar/gkz586. [Epub ahead of print]

PMID:
31276584
2.

CRISPR/Cas9-mediated deletion of the Wiskott-Aldrich syndrome locus causes actin cytoskeleton disorganization in murine erythroleukemia cells.

Fernández-Calleja V, Fernández-Nestosa MJ, Hernández P, Schvartzman JB, Krimer DB.

PeerJ. 2019 Jan 16;7:e6284. doi: 10.7717/peerj.6284. eCollection 2019.

3.

Analysis of DNA topology of EBV minichromosomes in HEK 293 cells.

Castán A, Fernández-Calleja V, Hernández P, Krimer DB, Schvartzman JB, Fernández-Nestosa MJ.

PLoS One. 2017 Nov 29;12(11):e0188172. doi: 10.1371/journal.pone.0188172. eCollection 2017.

4.

DNA Catenation Reveals the Dynamics of DNA Topology During Replication.

Castán A, Hernández P, Krimer DB, Schvartzman JB.

Methods Mol Biol. 2018;1703:75-86. doi: 10.1007/978-1-4939-7459-7_5.

PMID:
29177734
5.

The abundance of Fob1 modulates the efficiency of rRFBs to stall replication forks.

Castán A, Hernández P, Krimer DB, Schvartzman JB.

Nucleic Acids Res. 2017 Sep 29;45(17):10089-10102. doi: 10.1093/nar/gkx655.

6.

Differential gene expression analysis by RNA-seq reveals the importance of actin cytoskeletal proteins in erythroleukemia cells.

Fernández-Calleja V, Hernández P, Schvartzman JB, García de Lacoba M, Krimer DB.

PeerJ. 2017 Jun 27;5:e3432. doi: 10.7717/peerj.3432. eCollection 2017.

7.

Direct Evidence for the Formation of Precatenanes during DNA Replication.

Cebrián J, Castán A, Martínez V, Kadomatsu-Hermosa MJ, Parra C, Fernández-Nestosa MJ, Schaerer C, Hernández P, Krimer DB, Schvartzman JB.

J Biol Chem. 2015 May 29;290(22):13725-35. doi: 10.1074/jbc.M115.642272. Epub 2015 Mar 31.

8.

Electrophoretic mobility of supercoiled, catenated and knotted DNA molecules.

Cebrián J, Kadomatsu-Hermosa MJ, Castán A, Martínez V, Parra C, Fernández-Nestosa MJ, Schaerer C, Martínez-Robles ML, Hernández P, Krimer DB, Stasiak A, Schvartzman JB.

Nucleic Acids Res. 2015 Feb 27;43(4):e24. doi: 10.1093/nar/gku1255. Epub 2014 Nov 20.

9.

Topoisomerase 2 is dispensable for the replication and segregation of small yeast artificial chromosomes (YACs).

Cebrián J, Monturus E, Martínez-Robles ML, Hernández P, Krimer DB, Schvartzman JB.

PLoS One. 2014 Aug 12;9(8):e104995. doi: 10.1371/journal.pone.0104995. eCollection 2014.

10.

DNA methylation-mediated silencing of PU.1 in leukemia cells resistant to cell differentiation.

Fernández-Nestosa MJ, Monturus E, Sánchez Z, Torres FS, Fernández AF, Fraga MF, Hernández P, Schvartzman JB, Krimer DB.

Springerplus. 2013 Aug 21;2:392. doi: 10.1186/2193-1801-2-392. eCollection 2013.

11.

Plasmid DNA topology assayed by two-dimensional agarose gel electrophoresis.

Schvartzman JB, Martínez-Robles ML, Hernández P, Krimer DB.

Methods Mol Biol. 2013;1054:121-32. doi: 10.1007/978-1-62703-565-1_7.

PMID:
23913288
12.

The benefit of DNA supercoiling during replication.

Schvartzman JB, Martínez-Robles ML, Hernández P, Krimer DB.

Biochem Soc Trans. 2013 Apr;41(2):646-51. doi: 10.1042/BST20120281. Review.

13.

2D gels and their third-dimension potential.

Schvartzman JB, Martínez-Robles ML, López V, Hernández P, Krimer DB.

Methods. 2012 Jun;57(2):170-8. doi: 10.1016/j.ymeth.2012.03.013. Epub 2012 Mar 24.

PMID:
22465282
14.

DNA replication fading as proliferating cells advance in their commitment to terminal differentiation.

Estefanía MM, Ganier O, Hernández P, Schvartzman JB, Mechali M, Krimer DB.

Sci Rep. 2012;2:279. doi: 10.1038/srep00279. Epub 2012 Feb 20.

15.

Topo IV is the topoisomerase that knots and unknots sister duplexes during DNA replication.

López V, Martínez-Robles ML, Hernández P, Krimer DB, Schvartzman JB.

Nucleic Acids Res. 2012 Apr;40(8):3563-73. doi: 10.1093/nar/gkr1237. Epub 2011 Dec 19.

16.

Positive supercoiling of mitotic DNA drives decatenation by topoisomerase II in eukaryotes.

Baxter J, Sen N, Martínez VL, De Carandini ME, Schvartzman JB, Diffley JF, Aragón L.

Science. 2011 Mar 11;331(6022):1328-32. doi: 10.1126/science.1201538.

17.

The fission yeast rDNA-binding protein Reb1 regulates G1 phase under nutritional stress.

Rodríguez-Sánchez L, Rodríguez-López M, García Z, Tenorio-Gómez M, Schvartzman JB, Krimer DB, Hernández P.

J Cell Sci. 2011 Jan 1;124(Pt 1):25-34. doi: 10.1242/jcs.070987. Epub 2010 Nov 30.

18.

The genome of Streptococcus pneumoniae is organized in topology-reacting gene clusters.

Ferrándiz MJ, Martín-Galiano AJ, Schvartzman JB, de la Campa AG.

Nucleic Acids Res. 2010 Jun;38(11):3570-81. doi: 10.1093/nar/gkq106. Epub 2010 Feb 21.

19.

Plasmid DNA replication and topology as visualized by two-dimensional agarose gel electrophoresis.

Schvartzman JB, Martínez-Robles ML, Hernández P, Krimer DB.

Plasmid. 2010 Jan;63(1):1-10. doi: 10.1016/j.plasmid.2009.11.001. Epub 2009 Nov 16.

PMID:
19925824
20.

Interplay of DNA supercoiling and catenation during the segregation of sister duplexes.

Martínez-Robles ML, Witz G, Hernández P, Schvartzman JB, Stasiak A, Krimer DB.

Nucleic Acids Res. 2009 Aug;37(15):5126-37. doi: 10.1093/nar/gkp530. Epub 2009 Jun 24.

21.

A redundancy of processes that cause replication fork stalling enhances recombination at two distinct sites in yeast rDNA.

Mayán-Santos MD, Martínez-Robles ML, Hernández P, Schvartzman JB, Krimer DB.

Mol Microbiol. 2008 Jul;69(2):361-75. doi: 10.1111/j.1365-2958.2008.06278.x.

22.

How do we ask for money? A view of funding for basic research.

Schvartzman JM, Schvartzman JB.

EMBO Rep. 2008 Mar;9(3):216-20. doi: 10.1038/embor.2008.16. No abstract available.

23.

DNA is more negatively supercoiled in bacterial plasmids than in minichromosomes isolated from budding yeast.

Mayán-Santos MD, Martínez-Robles ML, Hernández P, Krimer D, Schvartzman JB.

Electrophoresis. 2007 Nov;28(21):3845-53.

24.

PU.1 is dispensable to block erythroid differentiation in Friend erythroleukemia cells.

Fernández-Nestosa MJ, Hernández P, Schvartzman JB, Krimer DB.

Leuk Res. 2008 Jan;32(1):121-30. Epub 2007 Jun 21.

PMID:
17586044
25.

Replication fork reversal occurs spontaneously after digestion but is constrained in supercoiled domains.

Fierro-Fernández M, Hernández P, Krimer DB, Schvartzman JB.

J Biol Chem. 2007 Jun 22;282(25):18190-6. Epub 2007 Apr 23.

26.

Topological locking restrains replication fork reversal.

Fierro-Fernández M, Hernández P, Krimer DB, Stasiak A, Schvartzman JB.

Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1500-5. Epub 2007 Jan 22.

27.

The mating type switch-activating protein Sap1 Is required for replication fork arrest at the rRNA genes of fission yeast.

Mejía-Ramírez E, Sánchez-Gorostiaga A, Krimer DB, Schvartzman JB, Hernández P.

Mol Cell Biol. 2005 Oct;25(19):8755-61.

28.

Protein kinase clk/STY is differentially regulated during erythroleukemia cell differentiation: a bias toward the skipped splice variant characterizes postcommitment stages.

García-Sacristán A, Fernández-Nestosa MJ, Hernández P, Schvartzman JB, Krimer DB.

Cell Res. 2005 Jul;15(7):495-503.

29.

A topological view of the replicon.

Schvartzman JB, Stasiak A.

EMBO Rep. 2004 Mar;5(3):256-61. Review.

30.

Transcription termination factor reb1p causes two replication fork barriers at its cognate sites in fission yeast ribosomal DNA in vivo.

Sánchez-Gorostiaga A, López-Estraño C, Krimer DB, Schvartzman JB, Hernández P.

Mol Cell Biol. 2004 Jan;24(1):398-406.

31.

Differential expression of Ran GTPase during HMBA-induced differentiation in murine erythroleukemia cells.

Vanegas N, García-Sacristán A, López-Fernández LA, Párraga M, del Mazo J, Hernández P, Schvartzman JB, Krimer DB.

Leuk Res. 2003 Jul;27(7):607-15.

PMID:
12681360
32.
33.

Knotting dynamics during DNA replication.

Olavarrieta L, Martínez-Robles ML, Hernández P, Krimer DB, Schvartzman JB.

Mol Microbiol. 2002 Nov;46(3):699-707.

34.

DNA knotting caused by head-on collision of transcription and replication.

Olavarrieta L, Hernández P, Krimer DB, Schvartzman JB.

J Mol Biol. 2002 Sep 6;322(1):1-6.

35.

Supercoiling, knotting and replication fork reversal in partially replicated plasmids.

Olavarrieta L, Martínez-Robles ML, Sogo JM, Stasiak A, Hernández P, Krimer DB, Schvartzman JB.

Nucleic Acids Res. 2002 Feb 1;30(3):656-66.

36.

Regulation of the switch from early to late bacteriophage lambda DNA replication.

Baranska S, Gabig M, Wegrzyn A, Konopa G, Herman-Antosiewicz A, Hernandez P, Schvartzman JB, Helinski DR, Wegrzyn G.

Microbiology. 2001 Mar;147(Pt 3):535-47.

PMID:
11238961
37.

Premature termination of DNA replication in plasmids carrying two inversely oriented ColE1 origins.

Santamaría D, Hernández P, Martínez-Robles ML, Krimer DB, Schvartzman JB.

J Mol Biol. 2000 Jun 30;300(1):75-82.

PMID:
10864499
38.

Bi-directional replication and random termination.

Santamaría D, Viguera E, Martínez-Robles ML, Hyrien O, Hernández P, Krimer DB, Schvartzman JB.

Nucleic Acids Res. 2000 May 15;28(10):2099-107.

39.

Visualisation of plasmid replication intermediates containing reversed forks.

Viguera E, Hernández P, Krimer DB, Lurz R, Schvartzman JB.

Nucleic Acids Res. 2000 Jan 15;28(2):498-503.

40.

Characterization of the pea rDNA replication fork barrier: putative cis-acting and trans-acting factors.

López-Estraño C, Schvartzman JB, Krimer DB, Hernández P.

Plant Mol Biol. 1999 May;40(1):99-110.

PMID:
10394949
41.

Formation of knots in partially replicated DNA molecules.

Sogo JM, Stasiak A, Martínez-Robles ML, Krimer DB, Hernández P, Schvartzman JB.

J Mol Biol. 1999 Feb 26;286(3):637-43.

42.

DnaB helicase is unable to dissociate RNA-DNA hybrids. Its implication in the polar pausing of replication forks at ColE1 origins.

Santamaría D, de la Cueva G, Martínez-Robles ML, Krimer DB, Hernández P, Schvartzman JB.

J Biol Chem. 1998 Dec 11;273(50):33386-96.

43.

A computer model for the analysis of DNA replication intermediates by two-dimensional agarose gel electrophoresis.

Viguera E, Rodríguez A, Hernández P, Krimer DB, Trellez O, Schvartzman JB.

Gene. 1998 Sep 14;217(1-2):41-9.

PMID:
9795124
44.

Topological complexity of different populations of pBR322 as visualized by two-dimensional agarose gel electrophoresis.

Martín-Parras L, Lucas I, Martínez-Robles ML, Hernández P, Krimer DB, Hyrien O, Schvartzman JB.

Nucleic Acids Res. 1998 Jul 15;26(14):3424-32.

45.

Co-localization of polar replication fork barriers and rRNA transcription terminators in mouse rDNA.

López-estraño C, Schvartzman JB, Krimer DB, Hernández P.

J Mol Biol. 1998 Mar 27;277(2):249-56.

PMID:
9514756
46.

Cloning, sequencing and expression in MEL cells of a cDNA encoding the mouse ribosomal protein S5.

Vanegas N, Castañeda V, Santamaría D, Hernández P, Schvartzman JB, Krimer DB.

Biochim Biophys Acta. 1997 Jun 5;1357(1):1-4.

47.

The ColE1 unidirectional origin acts as a polar replication fork pausing site.

Viguera E, Hernández P, Krimer DB, Boistov AS, Lurz R, Alonso JC, Schvartzman JB.

J Biol Chem. 1996 Sep 13;271(37):22414-21.

48.
49.

Conserved features in the mode of replication of eukaryotic ribosomal RNA genes.

Hernández P, Martín-Parras L, Martínez-Robles ML, Schvartzman JB.

EMBO J. 1993 Apr;12(4):1475-85.

50.

Initiation of DNA replication in ColE1 plasmids containing multiple potential origins of replication.

Martín-Parras L, Hernández P, Martínez-Robles ML, Schvartzman JB.

J Biol Chem. 1992 Nov 5;267(31):22496-505.

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