Sort by
Items per page

Send to

Choose Destination

Search results

Items: 49


Germ Line Deletion Reveals a Nonessential Role of Atypical Mitogen-Activated Protein Kinase 6/Extracellular Signal-Regulated Kinase 3.

Ronkina N, Schuster-Gossler K, Hansmann F, Kunze-Schumacher H, Sandrock I, Yakovleva T, Lafera J, Baumgärtner W, Krueger A, Prinz I, Gossler A, Kotlyarov A, Gaestel M.

Mol Cell Biol. 2019 Mar 1;39(6). pii: e00516-18. doi: 10.1128/MCB.00516-18. Print 2019 Mar 15.


The ectodomains determine ligand function in vivo and selectivity of DLL1 and DLL4 toward NOTCH1 and NOTCH2 in vitro.

Tveriakhina L, Schuster-Gossler K, Jarrett SM, Andrawes MB, Rohrbach M, Blacklow SC, Gossler A.

Elife. 2018 Oct 5;7. pii: e40045. doi: 10.7554/eLife.40045.


The evolutionary conserved FOXJ1 target gene Fam183b is essential for motile cilia in Xenopus but dispensable for ciliary function in mice.

Beckers A, Ott T, Schuster-Gossler K, Boldt K, Alten L, Ueffing M, Blum M, Gossler A.

Sci Rep. 2018 Oct 2;8(1):14678. doi: 10.1038/s41598-018-33045-2.


Functional characterization of the mouse Serpina1 paralog DOM-7.

Jülicher K, Wähner A, Haase K, Barbour KW, Berger FG, Wiehlmann L, Davenport C, Schuster-Gossler K, Stitz J, Cantz T, Eggenschwiler R.

Biol Chem. 2018 May 24;399(6):577-582. doi: 10.1515/hsz-2018-0154.


A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development.

Bohnenpoll T, Wittern AB, Mamo TM, Weiss AC, Rudat C, Kleppa MJ, Schuster-Gossler K, Wojahn I, Lüdtke TH, Trowe MO, Kispert A.

PLoS Genet. 2017 Aug 10;13(8):e1006951. doi: 10.1371/journal.pgen.1006951. eCollection 2017 Aug.


1700012B09Rik, a FOXJ1 effector gene active in ciliated tissues of the mouse but not essential for motile ciliogenesis.

Stauber M, Boldt K, Wrede C, Weidemann M, Kellner M, Schuster-Gossler K, Kühnel MP, Hegermann J, Ueffing M, Gossler A.

Dev Biol. 2017 Sep 1;429(1):186-199. doi: 10.1016/j.ydbio.2017.06.027. Epub 2017 Jun 28.


CFAP157 is a murine downstream effector of FOXJ1 that is specifically required for flagellum morphogenesis and sperm motility.

Weidemann M, Schuster-Gossler K, Stauber M, Wrede C, Hegermann J, Ott T, Boldt K, Beyer T, Serth K, Kremmer E, Blum M, Ueffing M, Gossler A.

Development. 2016 Dec 15;143(24):4736-4748.


Context-Dependent Sensitivity to Mutations Disrupting the Structural Integrity of Individual EGF Repeats in the Mouse Notch Ligand DLL1.

Schuster-Gossler K, Cordes R, Müller J, Geffers I, Delany-Heiken P, Taft M, Preller M, Gossler A.

Genetics. 2016 Mar;202(3):1119-33. doi: 10.1534/genetics.115.184515. Epub 2016 Jan 22.


Generation of an 870 kb deletion encompassing the Skt/Etl4 locus by combination of inter- and intra-chromosomal recombination.

Serth K, Beckers A, Schuster-Gossler K, Pavlova MN, Müller J, Paul MC, Reinhardt R, Gossler A.

BMC Genet. 2015 Dec 18;16:143. doi: 10.1186/s12863-015-0302-0.


Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo.

Preuße K, Tveriakhina L, Schuster-Gossler K, Gaspar C, Rosa AI, Henrique D, Gossler A, Stauber M.

PLoS Genet. 2015 Jun 26;11(6):e1005328. doi: 10.1371/journal.pgen.1005328. eCollection 2015 Jun.


O-fucosylation of DLL3 is required for its function during somitogenesis.

Serth K, Schuster-Gossler K, Kremmer E, Hansen B, Marohn-Köhn B, Gossler A.

PLoS One. 2015 Apr 9;10(4):e0123776. doi: 10.1371/journal.pone.0123776. eCollection 2015.


Upk3b is dispensable for development and integrity of urothelium and mesothelium.

Rudat C, Grieskamp T, Röhr C, Airik R, Wrede C, Hegermann J, Herrmann BG, Schuster-Gossler K, Kispert A.

PLoS One. 2014 Nov 12;9(11):e112112. doi: 10.1371/journal.pone.0112112. eCollection 2014.


Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis.

Menon MB, Sawada A, Chaturvedi A, Mishra P, Schuster-Gossler K, Galla M, Schambach A, Gossler A, Förster R, Heuser M, Kotlyarov A, Kinoshita M, Gaestel M.

PLoS Genet. 2014 Aug 14;10(8):e1004558. doi: 10.1371/journal.pgen.1004558. eCollection 2014 Aug.


S/T phosphorylation of DLL1 is required for full ligand activity in vitro but dispensable for DLL1 function in vivo during embryonic patterning and marginal zone B cell development.

Braune EB, Schuster-Gossler K, Lyszkiewicz M, Serth K, Preusse K, Madlung J, Macek B, Krueger A, Gossler A.

Mol Cell Biol. 2014 Apr;34(7):1221-33. doi: 10.1128/MCB.00965-13. Epub 2014 Jan 21.


Normal development in mice over-expressing the intracellular domain of DLL1 argues against reverse signaling by DLL1 in vivo.

Redeker C, Schuster-Gossler K, Kremmer E, Gossler A.

PLoS One. 2013 Oct 22;8(10):e79050. doi: 10.1371/journal.pone.0079050. eCollection 2013.


Tbx2 terminates shh/fgf signaling in the developing mouse limb bud by direct repression of gremlin1.

Farin HF, Lüdtke TH, Schmidt MK, Placzko S, Schuster-Gossler K, Petry M, Christoffels VM, Kispert A.

PLoS Genet. 2013;9(4):e1003467. doi: 10.1371/journal.pgen.1003467. Epub 2013 Apr 25.


Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b.

Lüdtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A.

PLoS Genet. 2013;9(1):e1003189. doi: 10.1371/journal.pgen.1003189. Epub 2013 Jan 17.


A novel mammal-specific three partite enhancer element regulates node and notochord-specific Noto expression.

Alten L, Schuster-Gossler K, Eichenlaub MP, Wittbrodt B, Wittbrodt J, Gossler A.

PLoS One. 2012;7(10):e47785. doi: 10.1371/journal.pone.0047785. Epub 2012 Oct 22.


Tbx18 function in epicardial development.

Greulich F, Farin HF, Schuster-Gossler K, Kispert A.

Cardiovasc Res. 2012 Dec 1;96(3):476-83. doi: 10.1093/cvr/cvs277. Epub 2012 Aug 27.


Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter.

Trowe MO, Airik R, Weiss AC, Farin HF, Foik AB, Bettenhausen E, Schuster-Gossler K, Taketo MM, Kispert A.

Development. 2012 Sep;139(17):3099-108. doi: 10.1242/dev.077388. Epub 2012 Jul 25.


Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1.

Alten L, Schuster-Gossler K, Beckers A, Groos S, Ulmer B, Hegermann J, Ochs M, Gossler A.

Development. 2012 Apr;139(7):1276-84. doi: 10.1242/dev.072728. Epub 2012 Feb 22.


Imprinted gene dosage is critical for the transition to independent life.

Charalambous M, Ferron SR, da Rocha ST, Murray AJ, Rowland T, Ito M, Schuster-Gossler K, Hernandez A, Ferguson-Smith AC.

Cell Metab. 2012 Feb 8;15(2):209-21. doi: 10.1016/j.cmet.2012.01.006.


Impaired stria vascularis integrity upon loss of E-cadherin in basal cells.

Trowe MO, Maier H, Petry M, Schweizer M, Schuster-Gossler K, Kispert A.

Dev Biol. 2011 Nov 1;359(1):95-107. doi: 10.1016/j.ydbio.2011.08.030. Epub 2011 Sep 9.


Erythropoietin preserves the endothelial differentiation capacity of cardiac progenitor cells and reduces heart failure during anticancer therapies.

Hoch M, Fischer P, Stapel B, Missol-Kolka E, Sekkali B, Scherr M, Favret F, Braun T, Eder M, Schuster-Gossler K, Gossler A, Hilfiker A, Balligand JL, Drexler H, Hilfiker-Kleiner D.

Cell Stem Cell. 2011 Aug 5;9(2):131-43. doi: 10.1016/j.stem.2011.07.001.


Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchyme.

Airik R, Trowe MO, Foik A, Farin HF, Petry M, Schuster-Gossler K, Schweizer M, Scherer G, Kist R, Kispert A.

Hum Mol Genet. 2010 Dec 15;19(24):4918-29. doi: 10.1093/hmg/ddq426. Epub 2010 Sep 29.


Loss of Sox9 in the periotic mesenchyme affects mesenchymal expansion and differentiation, and epithelial morphogenesis during cochlea development in the mouse.

Trowe MO, Shah S, Petry M, Airik R, Schuster-Gossler K, Kist R, Kispert A.

Dev Biol. 2010 Jun 1;342(1):51-62. doi: 10.1016/j.ydbio.2010.03.014. Epub 2010 Mar 24.


Amino acid polymorphisms altering the glycosylation of IL-2 do not protect from type 1 diabetes in the NOD mouse.

Kamanaka M, Rainbow D, Schuster-Gossler K, Eynon EE, Chervonsky AV, Wicker LS, Flavell RA.

Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11236-40. doi: 10.1073/pnas.0904780106. Epub 2009 Jun 22.


Notch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse development.

Schuster-Gossler K, Harris B, Johnson KR, Serth J, Gossler A.

BMC Dev Biol. 2009 Jan 22;9:6. doi: 10.1186/1471-213X-9-6.


Formation of the sinus node head and differentiation of sinus node myocardium are independently regulated by Tbx18 and Tbx3.

Wiese C, Grieskamp T, Airik R, Mommersteeg MT, Gardiwal A, de Gier-de Vries C, Schuster-Gossler K, Moorman AF, Kispert A, Christoffels VM.

Circ Res. 2009 Feb 13;104(3):388-97. doi: 10.1161/CIRCRESAHA.108.187062. Epub 2008 Dec 18.


Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.

Koch U, Fiorini E, Benedito R, Besseyrias V, Schuster-Gossler K, Pierres M, Manley NR, Duarte A, Macdonald HR, Radtke F.

J Exp Med. 2008 Oct 27;205(11):2515-23. doi: 10.1084/jem.20080829. Epub 2008 Sep 29.


Noncyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation.

Feller J, Schneider A, Schuster-Gossler K, Gossler A.

Genes Dev. 2008 Aug 15;22(16):2166-71. doi: 10.1101/gad.480408.


Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo.

Geffers I, Serth K, Chapman G, Jaekel R, Schuster-Gossler K, Cordes R, Sparrow DB, Kremmer E, Dunwoodie SL, Klein T, Gossler A.

J Cell Biol. 2007 Jul 30;178(3):465-76.


Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors.

Farin HF, Bussen M, Schmidt MK, Singh MK, Schuster-Gossler K, Kispert A.

J Biol Chem. 2007 Aug 31;282(35):25748-59. Epub 2007 Jun 21.


Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron.

Cheng HT, Kim M, Valerius MT, Surendran K, Schuster-Gossler K, Gossler A, McMahon AP, Kopan R.

Development. 2007 Feb;134(4):801-11. Epub 2007 Jan 17.


Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants.

Schuster-Gossler K, Cordes R, Gossler A.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):537-42. Epub 2006 Dec 28.


Mesodermal and neuronal retinoids regulate the induction and maintenance of limb innervating spinal motor neurons.

Ji SJ, Zhuang B, Falco C, Schneider A, Schuster-Gossler K, Gossler A, Sockanathan S.

Dev Biol. 2006 Sep 1;297(1):249-61. Epub 2006 May 19.


Formation of the venous pole of the heart from an Nkx2-5-negative precursor population requires Tbx18.

Christoffels VM, Mommersteeg MT, Trowe MO, Prall OW, de Gier-de Vries C, Soufan AT, Bussen M, Schuster-Gossler K, Harvey RP, Moorman AF, Kispert A.

Circ Res. 2006 Jun 23;98(12):1555-63. Epub 2006 May 18.


Aberrant regulation of imprinted gene expression in Gtl2lacZ mice.

Sekita Y, Wagatsuma H, Irie M, Kobayashi S, Kohda T, Matsuda J, Yokoyama M, Ogura A, Schuster-Gossler K, Gossler A, Ishino F, Kaneko-Ishino T.

Cytogenet Genome Res. 2006;113(1-4):223-9.


Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2.

Singh MK, Christoffels VM, Dias JM, Trowe MO, Petry M, Schuster-Gossler K, Bürger A, Ericson J, Kispert A.

Development. 2005 Jun;132(12):2697-707. Epub 2005 May 18.


WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos.

Hofmann M, Schuster-Gossler K, Watabe-Rudolph M, Aulehla A, Herrmann BG, Gossler A.

Genes Dev. 2004 Nov 15;18(22):2712-7.


The mouse homeobox gene Not is required for caudal notochord development and affected by the truncate mutation.

Abdelkhalek HB, Beckers A, Schuster-Gossler K, Pavlova MN, Burkhardt H, Lickert H, Rossant J, Reinhardt R, Schalkwyk LC, Müller I, Herrmann BG, Ceolin M, Rivera-Pomar R, Gossler A.

Genes Dev. 2004 Jul 15;18(14):1725-36. Epub 2004 Jul 1.


The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments.

Bussen M, Petry M, Schuster-Gossler K, Leitges M, Gossler A, Kispert A.

Genes Dev. 2004 May 15;18(10):1209-21.


Specification of vertebral identity is coupled to Notch signalling and the segmentation clock.

Cordes R, Schuster-Gossler K, Serth K, Gossler A.

Development. 2004 Mar;131(6):1221-33. Epub 2004 Feb 11.


Transcriptional oscillation of lunatic fringe is essential for somitogenesis.

Serth K, Schuster-Gossler K, Cordes R, Gossler A.

Genes Dev. 2003 Apr 1;17(7):912-25.


Use of coisogenic host blastocysts for efficient establishment of germline chimeras with C57BL/6J ES cell lines.

Schuster-Gossler K, Lee AW, Lerner CP, Parker HJ, Dyer VW, Scott VE, Gossler A, Conover JC.

Biotechniques. 2001 Nov;31(5):1022-4, 1026.


Gtl2lacZ, an insertional mutation on mouse chromosome 12 with parental origin-dependent phenotype.

Schuster-Gossler K, Simon-Chazottes D, Guenet JL, Zachgo J, Gossler A.

Mamm Genome. 1996 Jan;7(1):20-4.


The Etl-1 gene encodes a nuclear protein differentially expressed during early mouse development.

Schoor M, Schuster-Gossler K, Gossler A.

Dev Dyn. 1993 Jul;197(3):227-37.

Supplemental Content

Loading ...
Support Center