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Items: 1 to 50 of 151

1.

Prevalence and risk factors for latent tuberculosis infection among healthcare workers in Morocco.

Sabri A, Quistrebert J, Naji Amrani H, Abid A, Zegmout A, Abderrhamani Ghorfi I, Souhi H, Boucaid A, Benali A, Abilkassem R, Kmari M, Hassani A, Lahcen B, Siah S, Schurr E, Boisson-Dupuis S, Casanova JL, Lahlou A, Laatiris A, Louzi L, Ouarssani A, Bourazza A, Aouragh A, Mustapha B, Messaoudi N, Agader A, Cobat A, Abel L, El Baghdadi J.

PLoS One. 2019 Aug 15;14(8):e0221081. doi: 10.1371/journal.pone.0221081. eCollection 2019.

2.

Natural selection contributed to immunological differences between hunter-gatherers and agriculturalists.

Harrison GF, Sanz J, Boulais J, Mina MJ, Grenier JC, Leng Y, Dumaine A, Yotova V, Bergey CM, Nsobya SL, Elledge SJ, Schurr E, Quintana-Murci L, Perry GH, Barreiro LB.

Nat Ecol Evol. 2019 Aug;3(8):1253-1264. doi: 10.1038/s41559-019-0947-6. Epub 2019 Jul 29.

PMID:
31358949
3.

Pleiotropic effects for Parkin and LRRK2 in leprosy type-1 reactions and Parkinson's disease.

Fava VM, Xu YZ, Lettre G, Van Thuc N, Orlova M, Thai VH, Tao S, Croteau N, Eldeeb MA, MacDougall EJ, Cambri G, Lahiri R, Adams L, Fon EA, Trempe JF, Cobat A, Alcaïs A, Abel L, Schurr E.

Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15616-15624. doi: 10.1073/pnas.1901805116. Epub 2019 Jul 15.

4.

Advances in the understanding of Mycobacterium tuberculosis transmission in HIV-endemic settings.

Peters JS, Andrews JR, Hatherill M, Hermans S, Martinez L, Schurr E, van der Heijden Y, Wood R, Rustomjee R, Kana BD.

Lancet Infect Dis. 2019 Mar;19(3):e65-e76. doi: 10.1016/S1473-3099(18)30477-8. Epub 2018 Dec 13. Review.

PMID:
30554995
5.

Neutrophils: Innate Effectors of TB Resistance?

Kroon EE, Coussens AK, Kinnear C, Orlova M, Möller M, Seeger A, Wilkinson RJ, Hoal EG, Schurr E.

Front Immunol. 2018 Nov 14;9:2637. doi: 10.3389/fimmu.2018.02637. eCollection 2018. Review.

6.

Moving toward Tuberculosis Elimination. Critical Issues for Research in Diagnostics and Therapeutics for Tuberculosis Infection.

Keshavjee S, Amanullah F, Cattamanchi A, Chaisson R, Dobos KM, Fox GJ, Gendelman HE, Gordon R, Hesseling A, Le Van H, Kampmann B, Kana B, Khuller G, Lewinsohn DM, Lewinsohn DA, Lin PL, Lu LL, Maartens G, Owen A, Protopopova M, Rengarajan J, Rubin E, Salgame P, Schurr E, Seddon JA, Swindells S, Tobin DM, Udwadia Z, Walzl G, Srinivasan S, Rustomjee R, Nahid P.

Am J Respir Crit Care Med. 2019 Mar 1;199(5):564-571. doi: 10.1164/rccm.201806-1053PP. No abstract available.

7.

Genetic Resistance to Mycobacterium tuberculosis Infection and Disease.

Möller M, Kinnear CJ, Orlova M, Kroon EE, van Helden PD, Schurr E, Hoal EG.

Front Immunol. 2018 Sep 27;9:2219. doi: 10.3389/fimmu.2018.02219. eCollection 2018. Review.

8.

Human genetics of mycobacterial disease.

Dallmann-Sauer M, Correa-Macedo W, Schurr E.

Mamm Genome. 2018 Aug;29(7-8):523-538. doi: 10.1007/s00335-018-9765-4. Epub 2018 Aug 16. Review.

9.

HIV persistence in mucosal CD4+ T cells within the lungs of adults receiving long-term suppressive antiretroviral therapy.

Costiniuk CT, Salahuddin S, Farnos O, Olivenstein R, Pagliuzza A, Orlova M, Schurr E, De Castro C, Bourbeau J, Routy JP, Ancuta P, Chomont N, Jenabian MA.

AIDS. 2018 Oct 23;32(16):2279-2289. doi: 10.1097/QAD.0000000000001962.

10.

Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection.

Simmons JD, Stein CM, Seshadri C, Campo M, Alter G, Fortune S, Schurr E, Wallis RS, Churchyard G, Mayanja-Kizza H, Boom WH, Hawn TR.

Nat Rev Immunol. 2018 Sep;18(9):575-589. doi: 10.1038/s41577-018-0025-3. Review.

11.

Bronchial perforation with aortic pseudo-aneurysm due to aspirated foreign body.

Schurr E, Bogot N, Kuint RC, Erez E, Springer C, Picard E.

Pediatr Int. 2018 Mar;60(3):313-315. doi: 10.1111/ped.13487. Epub 2018 Feb 13. No abstract available.

PMID:
29436072
12.

Human Genomics of Mycobacterium tuberculosis Infection and Disease.

Orlova M, Schurr E.

Curr Genet Med Rep. 2017 Sep;5(3):125-131. doi: 10.1007/s40142-017-0124-7. Epub 2017 Jul 25.

13.

Genetics of human susceptibility to active and latent tuberculosis: present knowledge and future perspectives.

Abel L, Fellay J, Haas DW, Schurr E, Srikrishna G, Urbanowski M, Chaturvedi N, Srinivasan S, Johnson DH, Bishai WR.

Lancet Infect Dis. 2018 Mar;18(3):e64-e75. doi: 10.1016/S1473-3099(17)30623-0. Epub 2017 Oct 27. Review.

PMID:
29111156
14.

An eQTL variant of ZXDC is associated with IFN-γ production following Mycobacterium tuberculosis antigen-specific stimulation.

Jabot-Hanin F, Cobat A, Feinberg J, Orlova M, Niay J, Deswarte C, Poirier C, Theodorou I, Bustamante J, Boisson-Dupuis S, Casanova JL, Alcaïs A, Hoal EG, Delacourt C, Schurr E, Abel L.

Sci Rep. 2017 Oct 9;7(1):12800. doi: 10.1038/s41598-017-13017-8.

15.

Deciphering the genetic control of gene expression following Mycobacterium leprae antigen stimulation.

Manry J, Nédélec Y, Fava VM, Cobat A, Orlova M, Thuc NV, Thai VH, Laval G, Barreiro LB, Schurr E.

PLoS Genet. 2017 Aug 9;13(8):e1006952. doi: 10.1371/journal.pgen.1006952. eCollection 2017 Aug.

16.

Evaluating the Impact of LTA4H Genotype and Immune Status on Survival From Tuberculous Meningitis.

Fava VM, Schurr E.

J Infect Dis. 2017 Apr 1;215(7):1011-1013. doi: 10.1093/infdis/jix052. No abstract available.

17.

Age-Dependent Association of TNFSF15/TNFSF8 Variants and Leprosy Type 1 Reaction.

Fava VM, Sales-Marques C, Alcaïs A, Moraes MO, Schurr E.

Front Immunol. 2017 Feb 14;8:155. doi: 10.3389/fimmu.2017.00155. eCollection 2017.

18.

A genome wide association study identifies a lncRna as risk factor for pathological inflammatory responses in leprosy.

Fava VM, Manry J, Cobat A, Orlova M, Van Thuc N, Moraes MO, Sales-Marques C, Stefani MM, Latini AC, Belone AF, Thai VH, Abel L, Alcaïs A, Schurr E.

PLoS Genet. 2017 Feb 21;13(2):e1006637. doi: 10.1371/journal.pgen.1006637. eCollection 2017 Feb.

19.

Utility of the QuantiFERON-TB Gold In-Tube assay for the diagnosis of tuberculosis in Moroccan children.

El Azbaoui S, Sabri A, Ouraini S, Hassani A, Asermouh A, Agadr A, Abilkassem R, Dini N, Kmari M, Akhaddar A, Laktati Z, Aieche S, El Hafidi N, Ben Brahim F, Bousfiha AA, Ailal F, Deswarte C, Schurr E, Amar L, Bustamante J, Boisson-Dupuis S, Casanova JL, Abel L, El Baghdadi J.

Int J Tuberc Lung Dis. 2016 Dec;20(12):1639-1646.

PMID:
27931340
20.

Pauci- and Multibacillary Leprosy: Two Distinct, Genetically Neglected Diseases.

Gaschignard J, Grant AV, Thuc NV, Orlova M, Cobat A, Huong NT, Ba NN, Thai VH, Abel L, Schurr E, Alcaïs A.

PLoS Negl Trop Dis. 2016 May 24;10(5):e0004345. doi: 10.1371/journal.pntd.0004345. eCollection 2016 May. Review.

21.

A Missense LRRK2 Variant Is a Risk Factor for Excessive Inflammatory Responses in Leprosy.

Fava VM, Manry J, Cobat A, Orlova M, Van Thuc N, Ba NN, Thai VH, Abel L, Alcaïs A, Schurr E; Canadian Lrrk2 in Inflammation Team (CLINT).

PLoS Negl Trop Dis. 2016 Feb 4;10(2):e0004412. doi: 10.1371/journal.pntd.0004412. eCollection 2016 Feb.

22.

Tuberculosis in Newborns: The Lessons of the "Lübeck Disaster" (1929-1933).

Fox GJ, Orlova M, Schurr E.

PLoS Pathog. 2016 Jan 21;12(1):e1005271. doi: 10.1371/journal.ppat.1005271. eCollection 2016 Jan. Review.

23.

A genome-wide association study of pulmonary tuberculosis in Morocco.

Grant AV, Sabri A, Abid A, Abderrahmani Rhorfi I, Benkirane M, Souhi H, Naji Amrani H, Alaoui-Tahiri K, Gharbaoui Y, Lazrak F, Sentissi I, Manessouri M, Belkheiri S, Zaid S, Bouraqadi A, El Amraoui N, Hakam M, Belkadi A, Orlova M, Boland A, Deswarte C, Amar L, Bustamante J, Boisson-Dupuis S, Casanova JL, Schurr E, El Baghdadi J, Abel L.

Hum Genet. 2016 Mar;135(3):299-307. doi: 10.1007/s00439-016-1633-2. Epub 2016 Jan 14.

24.

Major Loci on Chromosomes 8q and 3q Control Interferon γ Production Triggered by Bacillus Calmette-Guerin and 6-kDa Early Secretory Antigen Target, Respectively, in Various Populations.

Jabot-Hanin F, Cobat A, Feinberg J, Grange G, Remus N, Poirier C, Boland-Auge A, Besse C, Bustamante J, Boisson-Dupuis S, Casanova JL, Schurr E, Alcaïs A, Hoal EG, Delacourt C, Abel L.

J Infect Dis. 2016 Apr 1;213(7):1173-9. doi: 10.1093/infdis/jiv757. Epub 2015 Dec 21.

25.

Pott's disease in Moroccan children: clinical features and investigation of the interleukin-12/interferon-γ pathway.

El Azbaoui S, Alaoui Mrani N, Sabri A, Jouhadi Z, Ailal F, Bousfiha AA, Najib J, El Hafidi N, Deswarte C, Schurr E, Bustamante J, Boisson-Dupuis S, Casanova JL, Abel L, El Baghdadi J.

Int J Tuberc Lung Dis. 2015 Dec;19(12):1455-62. doi: 10.5588/ijtld.15.0290.

26.

Specific dysregulation of IFNγ production by natural killer cells confers susceptibility to viral infection.

Fodil N, Langlais D, Moussa P, Boivin GA, Di Pietrantonio T, Radovanovic I, Dumaine A, Blanchette M, Schurr E, Gros P, Vidal SM.

PLoS Pathog. 2014 Dec 4;10(12):e1004511. doi: 10.1371/journal.ppat.1004511. eCollection 2014 Dec.

27.

Association of TNFSF8 regulatory variants with excessive inflammatory responses but not leprosy per se.

Fava VM, Cobat A, Van Thuc N, Latini AC, Stefani MM, Belone AF, Ba NN, Orlova M, Manry J, Mira MT, Thai VH, Abel L, Alcaïs A, Schurr E.

J Infect Dis. 2015 Mar 15;211(6):968-77. doi: 10.1093/infdis/jiu566. Epub 2014 Oct 15.

PMID:
25320285
28.

Tuberculin skin test negativity is under tight genetic control of chromosomal region 11p14-15 in settings with different tuberculosis endemicities.

Cobat A, Poirier C, Hoal E, Boland-Auge A, de La Rocque F, Corrard F, Grange G, Migaud M, Bustamante J, Boisson-Dupuis S, Casanova JL, Schurr E, Alcaïs A, Delacourt C, Abel L.

J Infect Dis. 2015 Jan 15;211(2):317-21. doi: 10.1093/infdis/jiu446. Epub 2014 Aug 20.

29.

The dissection of complex susceptibility to infectious disease: bacterial, viral and parasitic infections.

Abel L, Alcaïs A, Schurr E.

Curr Opin Immunol. 2014 Oct;30:72-8. doi: 10.1016/j.coi.2014.07.002. Epub 2014 Jul 31. Review.

PMID:
25083600
30.

A general efficient and flexible approach for genome-wide association analyses of imputed genotypes in family-based designs.

Cobat A, Abel L, Alcaïs A, Schurr E.

Genet Epidemiol. 2014 Sep;38(6):560-71. doi: 10.1002/gepi.21842. Epub 2014 Jul 8.

PMID:
25044438
31.

Pediatric vasitis: A rare complication of epididymitis.

Schurr E, Cytter-Kuint R, Ehrlichman M, Weiser G.

Can Urol Assoc J. 2014 May;8(5-6):E436-8. doi: 10.5489/cuaj.1892.

32.

Human genetics of tuberculosis: a long and winding road.

Abel L, El-Baghdadi J, Bousfiha AA, Casanova JL, Schurr E.

Philos Trans R Soc Lond B Biol Sci. 2014 May 12;369(1645):20130428. doi: 10.1098/rstb.2013.0428. Print 2014. Review.

33.

Association study of genes controlling IL-12-dependent IFN-γ immunity: STAT4 alleles increase risk of pulmonary tuberculosis in Morocco.

Sabri A, Grant AV, Cosker K, El Azbaoui S, Abid A, Abderrahmani Rhorfi I, Souhi H, Janah H, Alaoui-Tahiri K, Gharbaoui Y, Benkirane M, Orlova M, Boland A, Deswarte C, Migaud M, Bustamante J, Schurr E, Boisson-Dupuis S, Casanova JL, Abel L, El Baghdadi J.

J Infect Dis. 2014 Aug 15;210(4):611-8. doi: 10.1093/infdis/jiu140. Epub 2014 Mar 8.

34.

CUBN and NEBL common variants in the chromosome 10p13 linkage region are associated with multibacillary leprosy in Vietnam.

Grant AV, Cobat A, Van Thuc N, Orlova M, Huong NT, Gaschignard J, Alter A, Ba NN, Thai VH, Abel L, Alcaïs A, Schurr E.

Hum Genet. 2014 Jul;133(7):883-93. doi: 10.1007/s00439-014-1430-8. Epub 2014 Feb 23.

PMID:
24563210
35.

Cell biology: A table for two.

Behr MA, Schurr E.

Nature. 2013 Sep 26;501(7468):498-9. doi: 10.1038/nature12555. Epub 2013 Sep 4. No abstract available.

PMID:
24005328
36.

Gene set signature of reversal reaction type I in leprosy patients.

Orlova M, Cobat A, Huong NT, Ba NN, Van Thuc N, Spencer J, Nédélec Y, Barreiro L, Thai VH, Abel L, Alcaïs A, Schurr E.

PLoS Genet. 2013;9(7):e1003624. doi: 10.1371/journal.pgen.1003624. Epub 2013 Jul 11.

37.

Identification of a major locus, TNF1, that controls BCG-triggered tumor necrosis factor production by leukocytes in an area hyperendemic for tuberculosis.

Cobat A, Hoal EG, Gallant CJ, Simkin L, Black GF, Stanley K, Jaïs JP, Yu TH, Boland-Auge A, Grange G, Delacourt C, van Helden P, Casanova JL, Abel L, Alcaïs A, Schurr E.

Clin Infect Dis. 2013 Oct;57(7):963-70. doi: 10.1093/cid/cit438. Epub 2013 Jun 25.

38.

Host genomics and control of tuberculosis infection.

Cobat A, Orlova M, Barrera LF, Schurr E.

Public Health Genomics. 2013;16(1-2):44-9. doi: 10.1159/000341499. Epub 2013 Mar 18. Review.

39.

Host-pathogen specificity in tuberculosis.

Di Pietrantonio T, Schurr E.

Adv Exp Med Biol. 2013;783:33-44. doi: 10.1007/978-1-4614-6111-1_2. Review.

PMID:
23468102
40.

Age-dependent association between pulmonary tuberculosis and common TOX variants in the 8q12-13 linkage region.

Grant AV, El Baghdadi J, Sabri A, El Azbaoui S, Alaoui-Tahiri K, Abderrahmani Rhorfi I, Gharbaoui Y, Abid A, Benkirane M, Raharimanga V, Richard V, Orlova M, Boland A, Migaud M, Okada S, Nolan DK, Bustamante J, Barreiro LB, Schurr E, Boisson-Dupuis S, Rasolofo V, Casanova JL, Abel L.

Am J Hum Genet. 2013 Mar 7;92(3):407-14. doi: 10.1016/j.ajhg.2013.01.013. Epub 2013 Feb 14.

41.

[Human genetics of tuberculosis].

El Baghdadi J, Grant AV, Sabri A, El Azbaoui S, Zaidi H, Cobat A, Schurr E, Boisson-Dupuis S, Casanova JL, Abel L.

Pathol Biol (Paris). 2013 Jan;61(1):11-6. doi: 10.1016/j.patbio.2013.01.004. Epub 2013 Feb 9. Review. French.

42.

PARK2 mediates interleukin 6 and monocyte chemoattractant protein 1 production by human macrophages.

de Léséleuc L, Orlova M, Cobat A, Girard M, Huong NT, Ba NN, Thuc NV, Truman R, Spencer JS, Adams L, Thai VH, Alcais A, Schurr E.

PLoS Negl Trop Dis. 2013;7(1):e2015. doi: 10.1371/journal.pntd.0002015. Epub 2013 Jan 17.

43.

Insights from animal models on the immunogenetics of leprosy: a review.

Adams LB, Pena MT, Sharma R, Hagge DA, Schurr E, Truman RW.

Mem Inst Oswaldo Cruz. 2012 Dec;107 Suppl 1:197-208. Review.

44.

Genetics of leprosy reactions: an overview.

Fava V, Orlova M, Cobat A, Alcaïs A, Mira M, Schurr E.

Mem Inst Oswaldo Cruz. 2012 Dec;107 Suppl 1:132-42. Review.

45.

Linkage disequilibrium pattern and age-at-diagnosis are critical for replicating genetic associations across ethnic groups in leprosy.

Alter A, Fava VM, Huong NT, Singh M, Orlova M, Van Thuc N, Katoch K, Thai VH, Ba NN, Abel L, Mehra N, Alcaïs A, Schurr E.

Hum Genet. 2013 Jan;132(1):107-16. doi: 10.1007/s00439-012-1227-6. Epub 2012 Sep 29.

PMID:
23052943
46.

Crohn's disease susceptibility genes are associated with leprosy in the Vietnamese population.

Grant AV, Alter A, Huong NT, Orlova M, Van Thuc N, Ba NN, Thai VH, Abel L, Schurr E, Alcais A.

J Infect Dis. 2012 Dec 1;206(11):1763-7. doi: 10.1093/infdis/jis588. Epub 2012 Sep 14.

PMID:
22984114
47.

Tuberculin skin test reactivity is dependent on host genetic background in Colombian tuberculosis household contacts.

Cobat A, Barrera LF, Henao H, Arbeláez P, Abel L, García LF, Schurr E, Alcaïs A.

Clin Infect Dis. 2012 Apr;54(7):968-71. doi: 10.1093/cid/cir972. Epub 2012 Jan 30.

48.

TNF -308G>A single nucleotide polymorphism is associated with leprosy among Brazilians: a genetic epidemiology assessment, meta-analysis, and functional study.

Cardoso CC, Pereira AC, Brito-de-Souza VN, Duraes SM, Ribeiro-Alves M, Nery JA, Francio ÂS, Vanderborght PR, Parelli FP, Alter A, Salgado JL, Sampaio EP, Santos AR, Oliveira ML, Sarno EN, Schurr E, Mira MT, Pacheco AG, Moraes MO.

J Infect Dis. 2011 Oct 15;204(8):1256-63. doi: 10.1093/infdis/jir521.

PMID:
21917899
49.

Genetics of infectious diseases: hidden etiologies and common pathways.

Orlova M, Di Pietrantonio T, Schurr E.

Clin Chem Lab Med. 2011 Sep;49(9):1427-37. doi: 10.1515/CCLM.2011.620. Epub 2011 May 27. Review.

PMID:
21619464
50.

Human leukocyte antigen class I region single-nucleotide polymorphisms are associated with leprosy susceptibility in Vietnam and India.

Alter A, Huong NT, Singh M, Orlova M, Van Thuc N, Katoch K, Gao X, Thai VH, Ba NN, Carrington M, Abel L, Mehra N, Alcaïs A, Schurr E.

J Infect Dis. 2011 May 1;203(9):1274-81. doi: 10.1093/infdis/jir024.

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