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Items: 1 to 50 of 64

1.

Multi-use of the sea: A wide array of opportunities from site-specific cases across Europe.

Bocci M, Sangiuliano SJ, Sarretta A, Ansong JO, Buchanan B, Kafas A, Caña-Varona M, Onyango V, Papaioannou E, Ramieri E, Schultz-Zehden A, Schupp MF, Vassilopoulou V, Vergílio M.

PLoS One. 2019 Apr 11;14(4):e0215010. doi: 10.1371/journal.pone.0215010. eCollection 2019.

2.

Correction to: A possible postsynaptic role for SNAP-25 in hippocampal synapses.

Hussain S, Ringsevjen H, Schupp M, Hvalby Ø, Sørensen JB, Jensen V, Davanger S.

Brain Struct Funct. 2019 Mar;224(2):533. doi: 10.1007/s00429-018-01823-3.

PMID:
30604006
3.

A possible postsynaptic role for SNAP-25 in hippocampal synapses.

Hussain S, Ringsevjen H, Schupp M, Hvalby Ø, Sørensen JB, Jensen V, Davanger S.

Brain Struct Funct. 2019 Mar;224(2):521-532. doi: 10.1007/s00429-018-1782-2. Epub 2018 Oct 30. Erratum in: Brain Struct Funct. 2019 Jan 2;:.

PMID:
30377802
4.

A Multicenter Phase II Study of AMG 337 in Patients with MET-Amplified Gastric/Gastroesophageal Junction/Esophageal Adenocarcinoma and Other MET-Amplified Solid Tumors.

Van Cutsem E, Karaszewska B, Kang YK, Chung HC, Shankaran V, Siena S, Go NF, Yang H, Schupp M, Cunningham D.

Clin Cancer Res. 2019 Apr 15;25(8):2414-2423. doi: 10.1158/1078-0432.CCR-18-1337. Epub 2018 Oct 26.

PMID:
30366938
5.

p53 Functions in Adipose Tissue Metabolism and Homeostasis.

Krstic J, Reinisch I, Schupp M, Schulz TJ, Prokesch A.

Int J Mol Sci. 2018 Sep 4;19(9). pii: E2622. doi: 10.3390/ijms19092622. Review.

6.

Liver-secreted RBP4 does not impair glucose homeostasis in mice.

Fedders R, Muenzner M, Weber P, Sommerfeld M, Knauer M, Kedziora S, Kast N, Heidenreich S, Raila J, Weger S, Henze A, Schupp M.

J Biol Chem. 2018 Sep 28;293(39):15269-15276. doi: 10.1074/jbc.RA118.004294. Epub 2018 Aug 20.

PMID:
30126844
7.

Loss of the Hematopoietic Stem Cell Factor GATA2 in the Osteogenic Lineage Impairs Trabecularization and Mechanical Strength of Bone.

Tolkachov A, Fischer C, Ambrosi TH, Bothe M, Han CT, Muenzner M, Mathia S, Salminen M, Seifert G, Thiele M, Duda GN, Meijsing SH, Sauer S, Schulz TJ, Schupp M.

Mol Cell Biol. 2018 May 29;38(12). pii: e00599-17. doi: 10.1128/MCB.00599-17. Print 2018 Jun 15.

8.

p53 as a Dichotomous Regulator of Liver Disease: The Dose Makes the Medicine.

Krstic J, Galhuber M, Schulz TJ, Schupp M, Prokesch A.

Int J Mol Sci. 2018 Mar 20;19(3). pii: E921. doi: 10.3390/ijms19030921. Review.

9.

Selective Mineralocorticoid Receptor Cofactor Modulation as Molecular Basis for Finerenone's Antifibrotic Activity.

Grune J, Beyhoff N, Smeir E, Chudek R, Blumrich A, Ban Z, Brix S, Betz IR, Schupp M, Foryst-Ludwig A, Klopfleisch R, Stawowy P, Houtman R, Kolkhof P, Kintscher U.

Hypertension. 2018 Apr;71(4):599-608. doi: 10.1161/HYPERTENSIONAHA.117.10360. Epub 2018 Feb 5.

PMID:
29437893
10.

Pharmacokinetics of carfilzomib in patients with advanced malignancies and varying degrees of hepatic impairment: an open-label, single-arm, phase 1 study.

Brown J, Plummer R, Bauer TM, Anthony S, Sarantopoulos J, De Vos F, White M, Schupp M, Ou Y, Vaishampayan U.

Exp Hematol Oncol. 2017 Oct 3;6:27. doi: 10.1186/s40164-017-0086-1. eCollection 2017.

11.

Retinol saturase coordinates liver metabolism by regulating ChREBP activity.

Heidenreich S, Witte N, Weber P, Goehring I, Tolkachov A, von Loeffelholz C, Döcke S, Bauer M, Stockmann M, Pfeiffer AFH, Birkenfeld AL, Pietzke M, Kempa S, Muenzner M, Schupp M.

Nat Commun. 2017 Aug 30;8(1):384. doi: 10.1038/s41467-017-00430-w.

12.

A Randomized, Placebo-Controlled, Phase 1b/2 Study of Rilotumumab or Ganitumab in Combination With Platinum-Based Chemotherapy as First-Line Treatment for Extensive-Stage Small-Cell Lung Cancer.

Glisson B, Besse B, Dols MC, Dubey S, Schupp M, Jain R, Jiang Y, Menon H, Nackaerts K, Orlov S, Paz-Ares L, Ramlau R, Tang R, Zhang Y, Zhu M.

Clin Lung Cancer. 2017 Nov;18(6):615-625.e8. doi: 10.1016/j.cllc.2017.05.007. Epub 2017 May 10.

PMID:
28601388
13.

Reciprocal regulation of carbon monoxide metabolism and the circadian clock.

Klemz R, Reischl S, Wallach T, Witte N, Jürchott K, Klemz S, Lang V, Lorenzen S, Knauer M, Heidenreich S, Xu M, Ripperger JA, Schupp M, Stanewsky R, Kramer A.

Nat Struct Mol Biol. 2017 Jan;24(1):15-22. doi: 10.1038/nsmb.3331. Epub 2016 Nov 28.

PMID:
27892932
14.

Interactions Between SNAP-25 and Synaptotagmin-1 Are Involved in Vesicle Priming, Clamping Spontaneous and Stimulating Evoked Neurotransmission.

Schupp M, Malsam J, Ruiter M, Scheutzow A, Wierda KD, Söllner TH, Sørensen JB.

J Neurosci. 2016 Nov 23;36(47):11865-11880.

15.

Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis.

Prokesch A, Graef FA, Madl T, Kahlhofer J, Heidenreich S, Schumann A, Moyschewitz E, Pristoynik P, Blaschitz A, Knauer M, Muenzner M, Bogner-Strauss JG, Dohr G, Schulz TJ, Schupp M.

FASEB J. 2017 Feb;31(2):732-742. doi: 10.1096/fj.201600845R. Epub 2016 Nov 3.

16.

Loss of BMP receptor type 1A in murine adipose tissue attenuates age-related onset of insulin resistance.

Schulz TJ, Graja A, Huang TL, Xue R, An D, Poehle-Kronawitter S, Lynes MD, Tolkachov A, O'Sullivan LE, Hirshman MF, Schupp M, Goodyear LJ, Mishina Y, Tseng YH.

Diabetologia. 2016 Aug;59(8):1769-77. doi: 10.1007/s00125-016-3990-8. Epub 2016 May 21.

17.

Diabetes prevalence in NZO females depends on estrogen action on liver fat content.

Lubura M, Hesse D, Kraemer M, Hallahan N, Schupp M, von Löffelholz C, Kriebel J, Rudovich N, Pfeiffer A, John C, Scheja L, Heeren J, Koliaki C, Roden M, Schürmann A.

Am J Physiol Endocrinol Metab. 2015 Dec 15;309(12):E968-80. doi: 10.1152/ajpendo.00338.2015. Epub 2015 Oct 20.

18.

FABP4-Cre Mediated Expression of Constitutively Active ChREBP Protects Against Obesity, Fatty Liver, and Insulin Resistance.

Nuotio-Antar AM, Poungvarin N, Li M, Schupp M, Mohammad M, Gerard S, Zou F, Chan L.

Endocrinology. 2015 Nov;156(11):4020-32. doi: 10.1210/en.2015-1210. Epub 2015 Aug 6.

19.

The Glucose Sensor ChREBP Links De Novo Lipogenesis to PPARγ Activity and Adipocyte Differentiation.

Witte N, Muenzner M, Rietscher J, Knauer M, Heidenreich S, Nuotio-Antar AM, Graef FA, Fedders R, Tolkachov A, Goehring I, Schupp M.

Endocrinology. 2015 Nov;156(11):4008-19. doi: 10.1210/EN.2015-1209. Epub 2015 Jul 16.

PMID:
26181104
20.

Retinol binding protein 4 and its membrane receptors: a metabolic perspective.

Fedders R, Muenzner M, Schupp M.

Horm Mol Biol Clin Investig. 2015 Apr;22(1):27-37. doi: 10.1515/hmbci-2015-0013. Review.

PMID:
25941915
21.

Transcriptional inhibition of etv2 expression is essential for embryonic cardiac development.

Schupp MO, Waas M, Chun CZ, Ramchandran R.

Dev Biol. 2014 Sep 1;393(1):71-83. doi: 10.1016/j.ydbio.2014.06.019. Epub 2014 Jun 28.

22.

The mammalian INDY homolog is induced by CREB in a rat model of type 2 diabetes.

Neuschäfer-Rube F, Lieske S, Kuna M, Henkel J, Perry RJ, Erion DM, Pesta D, Willmes DM, Brachs S, von Loeffelholz C, Tolkachov A, Schupp M, Pathe-Neuschäfer-Rube A, Pfeiffer AF, Shulman GI, Püschel GP, Birkenfeld AL.

Diabetes. 2014 Mar;63(3):1048-57. doi: 10.2337/db13-0749. Epub 2013 Nov 12.

23.

Metabolite and transcriptome analysis during fasting suggest a role for the p53-Ddit4 axis in major metabolic tissues.

Schupp M, Chen F, Briggs ER, Rao S, Pelzmann HJ, Pessentheiner AR, Bogner-Strauss JG, Lazar MA, Baldwin D, Prokesch A.

BMC Genomics. 2013 Nov 5;14:758. doi: 10.1186/1471-2164-14-758.

24.

Mmp17b is essential for proper neural crest cell migration in vivo.

Leigh NR, Schupp MO, Li K, Padmanabhan V, Gastonguay A, Wang L, Chun CZ, Wilkinson GA, Ramchandran R.

PLoS One. 2013 Oct 1;8(10):e76484. doi: 10.1371/journal.pone.0076484. eCollection 2013.

25.

Retinol-binding protein 4 and its membrane receptor STRA6 control adipogenesis by regulating cellular retinoid homeostasis and retinoic acid receptor α activity.

Muenzner M, Tuvia N, Deutschmann C, Witte N, Tolkachov A, Valai A, Henze A, Sander LE, Raila J, Schupp M.

Mol Cell Biol. 2013 Oct;33(20):4068-82. doi: 10.1128/MCB.00221-13. Epub 2013 Aug 19.

26.

Residues in the pore region of Drosophila transient receptor potential A1 dictate sensitivity to thermal stimuli.

Wang H, Schupp M, Zurborg S, Heppenstall PA.

J Physiol. 2013 Jan 1;591(1):185-201. doi: 10.1113/jphysiol.2012.242842. Epub 2012 Oct 1.

27.

GTPase ARFRP1 is essential for normal hepatic glycogen storage and insulin-like growth factor 1 secretion.

Hesse D, Jaschke A, Kanzleiter T, Witte N, Augustin R, Hommel A, Püschel GP, Petzke KJ, Joost HG, Schupp M, Schürmann A.

Mol Cell Biol. 2012 Nov;32(21):4363-74. doi: 10.1128/MCB.00522-12. Epub 2012 Aug 27.

28.

Changes in response properties of rostral ventromedial medulla neurons during prolonged inflammation: modulation by neurokinin-1 receptors.

Khasabov SG, Brink TS, Schupp M, Noack J, Simone DA.

Neuroscience. 2012 Nov 8;224:235-48. doi: 10.1016/j.neuroscience.2012.08.029. Epub 2012 Aug 20.

29.

Histone deacetylase 6 (HDAC6) is an essential modifier of glucocorticoid-induced hepatic gluconeogenesis.

Winkler R, Benz V, Clemenz M, Bloch M, Foryst-Ludwig A, Wardat S, Witte N, Trappiel M, Namsolleck P, Mai K, Spranger J, Matthias G, Roloff T, Truee O, Kappert K, Schupp M, Matthias P, Kintscher U.

Diabetes. 2012 Feb;61(2):513-23. doi: 10.2337/db11-0313. Epub 2011 Dec 30.

30.

Repressor transcription factor 7-like 1 promotes adipogenic competency in precursor cells.

Cristancho AG, Schupp M, Lefterova MI, Cao S, Cohen DM, Chen CS, Steger DJ, Lazar MA.

Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16271-6. doi: 10.1073/pnas.1109409108. Epub 2011 Sep 13.

31.

Sox factors transcriptionally regulate ROBO4 gene expression in developing vasculature in zebrafish.

Samant GV, Schupp MO, François M, Moleri S, Kothinti RK, Chun CZ, Sinha I, Sellars S, Leigh N, Pramanik K, Horswill MA, Remadevi I, Li K, Wilkinson GA, Tabatabai NM, Beltrame M, Koopman P, Ramchandran R.

J Biol Chem. 2011 Sep 2;286(35):30740-7. doi: 10.1074/jbc.M111.220665. Epub 2011 Jul 5.

32.

Fli+ etsrp+ hemato-vascular progenitor cells proliferate at the lateral plate mesoderm during vasculogenesis in zebrafish.

Chun CZ, Remadevi I, Schupp MO, Samant GV, Pramanik K, Wilkinson GA, Ramchandran R.

PLoS One. 2011 Feb 25;6(2):e14732. doi: 10.1371/journal.pone.0014732.

33.

Endogenous ligands for nuclear receptors: digging deeper.

Schupp M, Lazar MA.

J Biol Chem. 2010 Dec 24;285(52):40409-15. doi: 10.1074/jbc.R110.182451. Epub 2010 Oct 18. Review.

34.

Liver-specific overexpression of pancreatic-derived factor (PANDER) induces fasting hyperglycemia in mice.

Wilson CG, Schupp M, Burkhardt BR, Wu J, Young RA, Wolf BA.

Endocrinology. 2010 Nov;151(11):5174-84. doi: 10.1210/en.2010-0379. Epub 2010 Sep 15.

35.

Propagation of adipogenic signals through an epigenomic transition state.

Steger DJ, Grant GR, Schupp M, Tomaru T, Lefterova MI, Schug J, Manduchi E, Stoeckert CJ Jr, Lazar MA.

Genes Dev. 2010 May 15;24(10):1035-44. doi: 10.1101/gad.1907110.

36.

Fingered for a fat fate.

Schupp M, Lazar MA.

Cell Metab. 2010 Apr 7;11(4):244-5. doi: 10.1016/j.cmet.2010.02.014.

37.

Characterization of the astacin family of metalloproteases in C. elegans.

Park JO, Pan J, Möhrlen F, Schupp MO, Johnsen R, Baillie DL, Zapf R, Moerman DG, Hutter H.

BMC Dev Biol. 2010 Jan 28;10:14. doi: 10.1186/1471-213X-10-14.

38.

Endoplasmic reticulum stress regulates adipocyte resistin expression.

Lefterova MI, Mullican SE, Tomaru T, Qatanani M, Schupp M, Lazar MA.

Diabetes. 2009 Aug;58(8):1879-86. doi: 10.2337/db08-1706. Epub 2009 Jun 2.

39.

Retinol saturase promotes adipogenesis and is downregulated in obesity.

Schupp M, Lefterova MI, Janke J, Leitner K, Cristancho AG, Mullican SE, Qatanani M, Szwergold N, Steger DJ, Curtin JC, Kim RJ, Suh MJ, Albert MR, Engeli S, Gudas LJ, Lazar MA.

Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1105-10. doi: 10.1073/pnas.0812065106. Epub 2009 Jan 12. Erratum in: Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4571. Suh, Moojin [corrected to Suh, Moo-Jin].

40.

Re-expression of GATA2 cooperates with peroxisome proliferator-activated receptor-gamma depletion to revert the adipocyte phenotype.

Schupp M, Cristancho AG, Lefterova MI, Hanniman EA, Briggs ER, Steger DJ, Qatanani M, Curtin JC, Schug J, Ochsner SA, McKenna NJ, Lazar MA.

J Biol Chem. 2009 Apr 3;284(14):9458-64. doi: 10.1074/jbc.M809498200. Epub 2009 Jan 9.

41.

Adipocyte-specific expression of murine resistin is mediated by synergism between peroxisome proliferator-activated receptor gamma and CCAAT/enhancer-binding proteins.

Tomaru T, Steger DJ, Lefterova MI, Schupp M, Lazar MA.

J Biol Chem. 2009 Mar 6;284(10):6116-25. doi: 10.1074/jbc.M808407200. Epub 2009 Jan 5.

42.

PPARgamma and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale.

Lefterova MI, Zhang Y, Steger DJ, Schupp M, Schug J, Cristancho A, Feng D, Zhuo D, Stoeckert CJ Jr, Liu XS, Lazar MA.

Genes Dev. 2008 Nov 1;22(21):2941-52. doi: 10.1101/gad.1709008.

43.

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.

Steger DJ, Lefterova MI, Ying L, Stonestrom AJ, Schupp M, Zhuo D, Vakoc AL, Kim JE, Chen J, Lazar MA, Blobel GA, Vakoc CR.

Mol Cell Biol. 2008 Apr;28(8):2825-39. doi: 10.1128/MCB.02076-07. Epub 2008 Feb 19.

44.

Liver-specific peroxisome proliferator-activated receptor alpha target gene regulation by the angiotensin type 1 receptor blocker telmisartan.

Clemenz M, Frost N, Schupp M, Caron S, Foryst-Ludwig A, Böhm C, Hartge M, Gust R, Staels B, Unger T, Kintscher U.

Diabetes. 2008 May;57(5):1405-13. doi: 10.2337/db07-0839. Epub 2008 Jan 9.

45.

Stereospecificity of retinol saturase: absolute configuration, synthesis, and biological evaluation of dihydroretinoids.

Moise AR, Domínguez M, Alvarez S, Alvarez R, Schupp M, Cristancho AG, Kiser PD, de Lera AR, Lazar MA, Palczewski K.

J Am Chem Soc. 2008 Jan 30;130(4):1154-5. doi: 10.1021/ja710487q. Epub 2008 Jan 8. No abstract available.

46.

Parvin-beta inhibits breast cancer tumorigenicity and promotes CDK9-mediated peroxisome proliferator-activated receptor gamma 1 phosphorylation.

Johnstone CN, Mongroo PS, Rich AS, Schupp M, Bowser MJ, Delemos AS, Tobias JW, Liu Y, Hannigan GE, Rustgi AK.

Mol Cell Biol. 2008 Jan;28(2):687-704. Epub 2007 Nov 12.

47.

PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo.

Kershaw EE, Schupp M, Guan HP, Gardner NP, Lazar MA, Flier JS.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1736-45. Epub 2007 Sep 11.

48.
49.

A widely used retinoic acid receptor antagonist induces peroxisome proliferator-activated receptor-gamma activity.

Schupp M, Curtin JC, Kim RJ, Billin AN, Lazar MA.

Mol Pharmacol. 2007 May;71(5):1251-7. Epub 2007 Feb 8.

PMID:
17290005
50.

Right ventricular tissue Doppler parameters in a patient with massive pulmonary embolus.

Schupp M, Bowry R, Tousignant CP.

J Am Soc Echocardiogr. 2007 Feb;20(2):198.e6-10.

PMID:
17275712

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