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Items: 1 to 50 of 105

1.

A Gene Expression Screen in Drosophila melanogaster Identifies Novel JAK/STAT and EGFR Targets During Oogenesis.

Wittes J, Schüpbach T.

G3 (Bethesda). 2019 Jan 9;9(1):47-60. doi: 10.1534/g3.118.200786.

2.

A quantitative model of developmental RTK signaling.

Goyal Y, Schüpbach T, Shvartsman SY.

Dev Biol. 2018 Oct 1;442(1):80-86. doi: 10.1016/j.ydbio.2018.07.012. Epub 2018 Jul 17. Review.

3.

Integrative analysis unveils new functions for the Drosophila Cutoff protein in noncoding RNA biogenesis and gene regulation.

Pritykin Y, Brito T, Schupbach T, Singh M, Pane A.

RNA. 2017 Jul;23(7):1097-1109. doi: 10.1261/rna.058594.116. Epub 2017 Apr 18.

4.

Stratum, a Homolog of the Human GEF Mss4, Partnered with Rab8, Controls the Basal Restriction of Basement Membrane Proteins in Epithelial Cells.

Devergne O, Sun GH, Schüpbach T.

Cell Rep. 2017 Feb 21;18(8):1831-1839. doi: 10.1016/j.celrep.2017.02.002.

5.

Divergent effects of intrinsically active MEK variants on developmental Ras signaling.

Goyal Y, Jindal GA, Pelliccia JL, Yamaya K, Yeung E, Futran AS, Burdine RD, Schüpbach T, Shvartsman SY.

Nat Genet. 2017 Mar;49(3):465-469. doi: 10.1038/ng.3780. Epub 2017 Feb 6.

6.

The Spatiotemporal Limits of Developmental Erk Signaling.

Johnson HE, Goyal Y, Pannucci NL, Schüpbach T, Shvartsman SY, Toettcher JE.

Dev Cell. 2017 Jan 23;40(2):185-192. doi: 10.1016/j.devcel.2016.12.002.

7.

In vivo severity ranking of Ras pathway mutations associated with developmental disorders.

Jindal GA, Goyal Y, Yamaya K, Futran AS, Kountouridis I, Balgobin CA, Schüpbach T, Burdine RD, Shvartsman SY.

Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):510-515. doi: 10.1073/pnas.1615651114. Epub 2017 Jan 3.

8.

Signaling through the G-protein-coupled receptor Rickets is important for polarity, detachment, and migration of the border cells in Drosophila.

Anllo L, Schüpbach T.

Dev Biol. 2016 Jun 15;414(2):193-206. doi: 10.1016/j.ydbio.2016.04.017. Epub 2016 Apr 26.

9.

The Complexities and Unexpected Insights of Developmental Genetic Analysis.

Schupbach T.

Curr Top Dev Biol. 2016;117:319-30. doi: 10.1016/bs.ctdb.2015.10.015. Epub 2016 Jan 7. Review.

PMID:
26969986
10.

Dynamics of Inductive ERK Signaling in the Drosophila Embryo.

Lim B, Dsilva CJ, Levario TJ, Lu H, Schüpbach T, Kevrekidis IG, Shvartsman SY.

Curr Biol. 2015 Jun 29;25(13):1784-90. doi: 10.1016/j.cub.2015.05.039. Epub 2015 Jun 18.

11.

Diversity of epithelial morphogenesis during eggshell formation in drosophilids.

Osterfield M, Schüpbach T, Wieschaus E, Shvartsman SY.

Development. 2015 Jun 1;142(11):1971-7. doi: 10.1242/dev.119404. Epub 2015 May 7.

12.

MorphoGraphX: A platform for quantifying morphogenesis in 4D.

Barbier de Reuille P, Routier-Kierzkowska AL, Kierzkowski D, Bassel GW, Schüpbach T, Tauriello G, Bajpai N, Strauss S, Weber A, Kiss A, Burian A, Hofhuis H, Sapala A, Lipowczan M, Heimlicher MB, Robinson S, Bayer EM, Basler K, Koumoutsakos P, Roeder AH, Aegerter-Wilmsen T, Nakayama N, Tsiantis M, Hay A, Kwiatkowska D, Xenarios I, Kuhlemeier C, Smith RS.

Elife. 2015 May 6;4:05864. doi: 10.7554/eLife.05864.

13.

Repression of Gurken translation by a meiotic checkpoint in Drosophila oogenesis is suppressed by a reduction in the dose of eIF1A.

Li W, Klovstad M, Schüpbach T.

Development. 2014 Oct;141(20):3910-21. doi: 10.1242/dev.109306. Epub 2014 Sep 17.

14.

Polarized deposition of basement membrane proteins depends on Phosphatidylinositol synthase and the levels of Phosphatidylinositol 4,5-bisphosphate.

Devergne O, Tsung K, Barcelo G, Schüpbach T.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7689-94. doi: 10.1073/pnas.1407351111. Epub 2014 May 14.

15.

Structure-activity relationships for a series of compounds that inhibit aggregation of the Alzheimer's peptide, Aβ42.

McKoy AF, Chen J, Schupbach T, Hecht MH.

Chem Biol Drug Des. 2014 Nov;84(5):505-12. doi: 10.1111/cbdd.12341. Epub 2014 May 21.

16.

Phantom, a cytochrome P450 enzyme essential for ecdysone biosynthesis, plays a critical role in the control of border cell migration in Drosophila.

Domanitskaya E, Anllo L, Schüpbach T.

Dev Biol. 2014 Feb 15;386(2):408-18. doi: 10.1016/j.ydbio.2013.12.013. Epub 2013 Dec 27.

17.

Calpain A modulates Toll responses by limited Cactus/IκB proteolysis.

Fontenele M, Lim B, Oliveira D, Buffolo M, Perlman DH, Schupbach T, Araujo H.

Mol Biol Cell. 2013 Sep;24(18):2966-80. doi: 10.1091/mbc.E13-02-0113. Epub 2013 Jul 17.

18.

Three-dimensional epithelial morphogenesis in the developing Drosophila egg.

Osterfield M, Du X, Schüpbach T, Wieschaus E, Shvartsman SY.

Dev Cell. 2013 Feb 25;24(4):400-10. doi: 10.1016/j.devcel.2013.01.017.

19.

A novel inhibitor of amyloid β (Aβ) peptide aggregation: from high throughput screening to efficacy in an animal model of Alzheimer disease.

McKoy AF, Chen J, Schupbach T, Hecht MH.

J Biol Chem. 2012 Nov 9;287(46):38992-9000. doi: 10.1074/jbc.M112.348037. Epub 2012 Sep 19.

20.

CoREST acts as a positive regulator of Notch signaling in the follicle cells of Drosophila melanogaster.

Domanitskaya E, Schüpbach T.

J Cell Sci. 2012 Jan 15;125(Pt 2):399-410. doi: 10.1242/jcs.089797. Epub 2012 Feb 13.

21.

Modulation of gurken translation by insulin and TOR signaling in Drosophila.

Ferguson SB, Blundon MA, Klovstad MS, Schüpbach T.

J Cell Sci. 2012 Mar 15;125(Pt 6):1407-19. doi: 10.1242/jcs.090381. Epub 2012 Feb 10.

22.

Comparison of strategies to detect epistasis from eQTL data.

Kapur K, Schüpbach T, Xenarios I, Kutalik Z, Bergmann S.

PLoS One. 2011;6(12):e28415. doi: 10.1371/journal.pone.0028415. Epub 2011 Dec 19.

23.

The Cutoff protein regulates piRNA cluster expression and piRNA production in the Drosophila germline.

Pane A, Jiang P, Zhao DY, Singh M, Schüpbach T.

EMBO J. 2011 Nov 16;30(22):4601-15. doi: 10.1038/emboj.2011.334.

24.

Pattern formation by receptor tyrosine kinases: analysis of the Gurken gradient in Drosophila oogenesis.

Cheung LS, Schüpbach T, Shvartsman SY.

Curr Opin Genet Dev. 2011 Dec;21(6):719-25. doi: 10.1016/j.gde.2011.07.009. Epub 2011 Aug 19. Review.

25.

Regulation of somatic myosin activity by protein phosphatase 1β controls Drosophila oocyte polarization.

Sun Y, Yan Y, Denef N, Schüpbach T.

Development. 2011 May;138(10):1991-2001. doi: 10.1242/dev.062190. Epub 2011 Apr 13.

26.

Drosophila PI4KIIIalpha is required in follicle cells for oocyte polarization and Hippo signaling.

Yan Y, Denef N, Tang C, Schüpbach T.

Development. 2011 May;138(9):1697-703. doi: 10.1242/dev.059279. Epub 2011 Mar 23.

27.

Rabconnectin-3 is a functional regulator of mammalian Notch signaling.

Sethi N, Yan Y, Quek D, Schupbach T, Kang Y.

J Biol Chem. 2010 Nov 5;285(45):34757-64. doi: 10.1074/jbc.M110.158634. Epub 2010 Sep 1.

28.

FastEpistasis: a high performance computing solution for quantitative trait epistasis.

Schüpbach T, Xenarios I, Bergmann S, Kapur K.

Bioinformatics. 2010 Jun 1;26(11):1468-9. doi: 10.1093/bioinformatics/btq147. Epub 2010 Apr 7.

29.

The vacuolar proton pump, V-ATPase, is required for notch signaling and endosomal trafficking in Drosophila.

Yan Y, Denef N, Schüpbach T.

Dev Cell. 2009 Sep;17(3):387-402. doi: 10.1016/j.devcel.2009.07.001.

30.

Developmental biology: Pipe's smoking guns.

Schüpbach T.

Curr Biol. 2009 Jul 28;19(14):R548-50. doi: 10.1016/j.cub.2009.05.053. Review.

31.

Fourier transform convolution integrals applied to generalized Born molecular volume.

Schüpbach T, Zoete V, Tsakam-Sotché B, Michielin O.

J Comput Chem. 2010 Feb;31(3):649-59. doi: 10.1002/jcc.21338. Review.

PMID:
19557764
32.

A combinatorial code for pattern formation in Drosophila oogenesis.

Yakoby N, Bristow CA, Gong D, Schafer X, Lembong J, Zartman JJ, Halfon MS, Schüpbach T, Shvartsman SY.

Dev Cell. 2008 Nov;15(5):725-37. doi: 10.1016/j.devcel.2008.09.008.

33.

Crag regulates epithelial architecture and polarized deposition of basement membrane proteins in Drosophila.

Denef N, Chen Y, Weeks SD, Barcelo G, Schüpbach T.

Dev Cell. 2008 Mar;14(3):354-64. doi: 10.1016/j.devcel.2007.12.012.

34.

The dynamics of fluorescently labeled endogenous gurken mRNA in Drosophila.

Jaramillo AM, Weil TT, Goodhouse J, Gavis ER, Schupbach T.

J Cell Sci. 2008 Mar 15;121(Pt 6):887-94. doi: 10.1242/jcs.019091. Epub 2008 Feb 26.

35.

Drosophila brca2 is required for mitotic and meiotic DNA repair and efficient activation of the meiotic recombination checkpoint.

Klovstad M, Abdu U, Schüpbach T.

PLoS Genet. 2008 Feb;4(2):e31. doi: 10.1371/journal.pgen.0040031.

36.

Squid, Cup, and PABP55B function together to regulate gurken translation in Drosophila.

Clouse KN, Ferguson SB, Schüpbach T.

Dev Biol. 2008 Jan 15;313(2):713-24. Epub 2007 Nov 19.

37.

Drosophila eggshell is patterned by sequential action of feedforward and feedback loops.

Yakoby N, Lembong J, Schüpbach T, Shvartsman SY.

Development. 2008 Jan;135(2):343-51. Epub 2007 Dec 12.

38.

Semiclassical expansion of the smooth part of the density of states, with application to the hydrogen atom in a uniform magnetic field.

Kunz H, Schüpbach T, Dupertuis MA.

Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Jul;76(1 Pt 2):016215. Epub 2007 Jul 23.

PMID:
17677551
39.
40.

Cutoff and aubergine mutations result in retrotransposon upregulation and checkpoint activation in Drosophila.

Chen Y, Pane A, Schüpbach T.

Curr Biol. 2007 Apr 3;17(7):637-42. Epub 2007 Mar 15.

41.

An essential role for Drosophila hus1 in somatic and meiotic DNA damage responses.

Abdu U, Klovstad M, Butin-Israeli V, Bakhrat A, Schüpbach T.

J Cell Sci. 2007 Mar 15;120(Pt 6):1042-9. Epub 2007 Feb 27.

43.

Systems-level questions in Drosophila oogenesis.

Yakoby N, Bristow CA, Gouzman I, Rossi MP, Gogotsi Y, Schüpbach T, Shvartsman SY.

Syst Biol (Stevenage). 2005 Dec;152(4):276-84. Review.

PMID:
16986271
44.

Quantitative models of developmental pattern formation.

Reeves GT, Muratov CB, Schüpbach T, Shvartsman SY.

Dev Cell. 2006 Sep;11(3):289-300. Review.

45.

Quantifying the Gurken morphogen gradient in Drosophila oogenesis.

Goentoro LA, Reeves GT, Kowal CP, Martinelli L, Schüpbach T, Shvartsman SY.

Dev Cell. 2006 Aug;11(2):263-72.

46.

Differential effects of Cbl isoforms on Egfr signaling in Drosophila.

Pai LM, Wang PY, Chen SR, Barcelo G, Chang WL, Nilson L, Schüpbach T.

Mech Dev. 2006 Jun;123(6):450-62. Epub 2006 Jul 17.

47.

Multiple EGFR ligands participate in guiding migrating border cells.

McDonald JA, Pinheiro EM, Kadlec L, Schupbach T, Montell DJ.

Dev Biol. 2006 Aug 1;296(1):94-103. Epub 2006 Apr 21.

48.

The role of brinker in eggshell patterning.

Chen Y, Schüpbach T.

Mech Dev. 2006 May;123(5):395-406. Epub 2006 May 16.

50.

spn-F encodes a novel protein that affects oocyte patterning and bristle morphology in Drosophila.

Abdu U, Bar D, Schüpbach T.

Development. 2006 Apr;133(8):1477-84. Epub 2006 Mar 15.

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