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Items: 1 to 50 of 208

1.

Local translation in neuronal processes.

Biever A, Donlin-Asp PG, Schuman EM.

Curr Opin Neurobiol. 2019 Mar 9;57:141-148. doi: 10.1016/j.conb.2019.02.008. [Epub ahead of print] Review.

PMID:
30861464
2.

Glutamate receptor trafficking and protein synthesis mediate the facilitation of ltp by secreted amyloid precursor protein-alpha.

Mockett BG, Guévremont D, Elder MK, Parfitt KD, Peppercorn K, Morrissey J, Singh A, Hintz TJ, Kochen L, Tom Dieck S, Schuman E, Tate WP, Williams JM, Abraham WC.

J Neurosci. 2019 Feb 25. pii: 1826-18. doi: 10.1523/JNEUROSCI.1826-18.2019. [Epub ahead of print]

PMID:
30804097
3.

ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans.

Kreis P, Gallrein C, Rojas-Puente E, Mack TGA, Kroon C, Dinkel V, Willmes C, Murk K, Tom-Dieck S, Schuman EM, Kirstein J, Eickholt BJ.

Nat Commun. 2019 Jan 30;10(1):486. doi: 10.1038/s41467-019-08420-w.

4.

Spatially Stable Mitochondrial Compartments Fuel Local Translation during Plasticity.

Rangaraju V, Lauterbach M, Schuman EM.

Cell. 2019 Jan 10;176(1-2):73-84.e15. doi: 10.1016/j.cell.2018.12.013. Epub 2019 Jan 3.

PMID:
30612742
5.

Cell-type-specific metabolic labeling, detection and identification of nascent proteomes in vivo.

Alvarez-Castelao B, Schanzenbächer CT, Langer JD, Schuman EM.

Nat Protoc. 2019 Feb;14(2):556-575. doi: 10.1038/s41596-018-0106-6.

PMID:
30610240
6.

A New Photocaged Puromycin for an Efficient Labeling of Newly Translated Proteins in Living Neurons.

Elamri I, Heumüller M, Herzig LM, Stirnal E, Wachtveitl J, Schuman EM, Schwalbe H.

Chembiochem. 2018 Dec 4;19(23):2458-2464. doi: 10.1002/cbic.201800408. Epub 2018 Nov 8.

PMID:
30311996
7.

Local and global influences on protein turnover in neurons and glia.

Dörrbaum AR, Kochen L, Langer JD, Schuman EM.

Elife. 2018 Jun 19;7. pii: e34202. doi: 10.7554/eLife.34202.

8.

Alternative 3' UTRs Modify the Localization, Regulatory Potential, Stability, and Plasticity of mRNAs in Neuronal Compartments.

Tushev G, Glock C, Heumüller M, Biever A, Jovanovic M, Schuman EM.

Neuron. 2018 May 2;98(3):495-511.e6. doi: 10.1016/j.neuron.2018.03.030. Epub 2018 Apr 12.

PMID:
29656876
9.

Time- and polarity-dependent proteomic changes associated with homeostatic scaling at central synapses.

Schanzenbächer CT, Langer JD, Schuman EM.

Elife. 2018 Feb 15;7. pii: e33322. doi: 10.7554/eLife.33322.

10.

Use of bovine carotid artery for buttonhole technique hemodialysis.

Schuman E, Alexander P, Ronfeld A.

J Vasc Access. 2018 Jan;19(1):89-91. doi: 10.5301/jva.5000800.

PMID:
29148012
11.

Cell-type-specific metabolic labeling of nascent proteomes in vivo.

Alvarez-Castelao B, Schanzenbächer CT, Hanus C, Glock C, Tom Dieck S, Dörrbaum AR, Bartnik I, Nassim-Assir B, Ciirdaeva E, Mueller A, Dieterich DC, Tirrell DA, Langer JD, Schuman EM.

Nat Biotechnol. 2017 Dec;35(12):1196-1201. doi: 10.1038/nbt.4016. Epub 2017 Nov 6.

PMID:
29106408
12.

mRNA transport & local translation in neurons.

Glock C, Heumüller M, Schuman EM.

Curr Opin Neurobiol. 2017 Aug;45:169-177. doi: 10.1016/j.conb.2017.05.005. Epub 2017 Jun 17. Review.

PMID:
28633045
13.

Local translation in neuronal compartments: how local is local?

Rangaraju V, Tom Dieck S, Schuman EM.

EMBO Rep. 2017 May;18(5):693-711. doi: 10.15252/embr.201744045. Epub 2017 Apr 12. Review.

14.

Management of Primary Hyperparathyroidism: Can We Do Better?

Sharata A, Kelly TL, Rozenfeld Y, Hammill CW, Schuman E, Carlisle JR, Aliabadi-Wahle S.

Am Surg. 2017 Jan 1;83(1):64-70.

PMID:
28234128
15.

Activity-dependent spatially localized miRNA maturation in neuronal dendrites.

Sambandan S, Akbalik G, Kochen L, Rinne J, Kahlstatt J, Glock C, Tushev G, Alvarez-Castelao B, Heckel A, Schuman EM.

Science. 2017 Feb 10;355(6325):634-637. doi: 10.1126/science.aaf8995.

PMID:
28183980
16.

Visualization of newly synthesized neuronal RNA in vitro and in vivo using click-chemistry.

Akbalik G, Langebeck-Jensen K, Tushev G, Sambandan S, Rinne J, Epstein I, Cajigas I, Vlatkovic I, Schuman EM.

RNA Biol. 2017 Jan 2;14(1):20-28. doi: 10.1080/15476286.2016.1251541. Epub 2016 Nov 1.

17.

Unconventional secretory processing diversifies neuronal ion channel properties.

Hanus C, Geptin H, Tushev G, Garg S, Alvarez-Castelao B, Sambandan S, Kochen L, Hafner AS, Langer JD, Schuman EM.

Elife. 2016 Sep 28;5. pii: e20609. doi: 10.7554/eLife.20609.

18.

Nascent Proteome Remodeling following Homeostatic Scaling at Hippocampal Synapses.

Schanzenbächer CT, Sambandan S, Langer JD, Schuman EM.

Neuron. 2016 Oct 19;92(2):358-371. doi: 10.1016/j.neuron.2016.09.058.

19.

Circular RNAs in Brain and Other Tissues: A Functional Enigma.

Chen W, Schuman E.

Trends Neurosci. 2016 Sep;39(9):597-604. doi: 10.1016/j.tins.2016.06.006. Epub 2016 Jul 18. Review.

PMID:
27445124
20.

Engineered Aminoacyl-tRNA Synthetase for Cell-Selective Analysis of Mammalian Protein Synthesis.

Mahdavi A, Hamblin GD, Jindal GA, Bagert JD, Dong C, Sweredoski MJ, Hess S, Schuman EM, Tirrell DA.

J Am Chem Soc. 2016 Apr 6;138(13):4278-81. doi: 10.1021/jacs.5b08980. Epub 2016 Mar 25.

21.

Rethinking Functional Segregation: Gradients of Gene Expression in Area CA1.

Tushev G, Schuman EM.

Neuron. 2016 Jan 20;89(2):242-3. doi: 10.1016/j.neuron.2016.01.002.

22.

NEUROSCIENCE. Opting in or out of the network.

Martin KC, Schuman EM.

Science. 2015 Dec 18;350(6267):1477-8. doi: 10.1126/science.aad9467. No abstract available.

23.

The Regulation of Synaptic Protein Turnover.

Alvarez-Castelao B, Schuman EM.

J Biol Chem. 2015 Nov 27;290(48):28623-30. doi: 10.1074/jbc.R115.657130. Epub 2015 Oct 9. Review.

24.

Direct visualization of newly synthesized target proteins in situ.

tom Dieck S, Kochen L, Hanus C, Heumüller M, Bartnik I, Nassim-Assir B, Merk K, Mosler T, Garg S, Bunse S, Tirrell DA, Schuman EM.

Nat Methods. 2015 May;12(5):411-4. doi: 10.1038/nmeth.3319. Epub 2015 Mar 16.

25.

Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.

You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.

Nat Neurosci. 2015 Apr;18(4):603-610. doi: 10.1038/nn.3975. Epub 2015 Feb 25.

26.

On physician assistant autonomy.

Schuman E.

JAAPA. 2015 Mar;28(3):1. doi: 10.1097/01.JAA.0000460983.26755.62. No abstract available.

PMID:
25710399
27.

Cell-specific proteomic analysis in Caenorhabditis elegans.

Yuet KP, Doma MK, Ngo JT, Sweredoski MJ, Graham RL, Moradian A, Hess S, Schuman EM, Sternberg PW, Tirrell DA.

Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2705-10. doi: 10.1073/pnas.1421567112. Epub 2015 Feb 17.

28.

Design of photocaged puromycin for nascent polypeptide release and spatiotemporal monitoring of translation.

Buhr F, Kohl-Landgraf J, tom Dieck S, Hanus C, Chatterjee D, Hegelein A, Schuman EM, Wachtveitl J, Schwalbe H.

Angew Chem Int Ed Engl. 2015 Mar 16;54(12):3717-21. doi: 10.1002/anie.201410940. Epub 2015 Feb 4.

PMID:
25656536
29.

Lateral assembly of N-cadherin drives tissue integrity by stabilizing adherens junctions.

Garg S, Fischer SC, Schuman EM, Stelzer EH.

J R Soc Interface. 2015 Mar 6;12(104):20141055. doi: 10.1098/rsif.2014.1055.

30.

BONCAT: metabolic labeling, click chemistry, and affinity purification of newly synthesized proteomes.

Landgraf P, Antileo ER, Schuman EM, Dieterich DC.

Methods Mol Biol. 2015;1266:199-215. doi: 10.1007/978-1-4939-2272-7_14.

PMID:
25560077
31.

Optimizing the performance of a reactor by reducing the retention time and addition of glycerin for anaerobically digesting manure.

Timmerman M, Schuman E, van Eekert M, van Riel J.

Environ Technol. 2015 May-Jun;36(9-12):1223-36. doi: 10.1080/09593330.2014.983989. Epub 2014 Dec 13.

32.

Treatment strategies for primary hyperparathyroidism: what is the cost?

Aliabadi-Wahle S, Kelly TL, Rozenfeld Y, Carlisle JR, Naeole LK, Negreanu FA, Schuman E, Hammill CW.

Am Surg. 2014 Nov;80(11):1146-51.

PMID:
25347507
33.

Synaptic control of secretory trafficking in dendrites.

Hanus C, Kochen L, Tom Dieck S, Racine V, Sibarita JB, Schuman EM, Ehlers MD.

Cell Rep. 2014 Jun 26;7(6):1771-8. doi: 10.1016/j.celrep.2014.05.028. Epub 2014 Jun 12.

34.

Correlative light- and electron microscopy with chemical tags.

Perkovic M, Kunz M, Endesfelder U, Bunse S, Wigge C, Yu Z, Hodirnau VV, Scheffer MP, Seybert A, Malkusch S, Schuman EM, Heilemann M, Frangakis AS.

J Struct Biol. 2014 May;186(2):205-13. doi: 10.1016/j.jsb.2014.03.018. Epub 2014 Mar 31.

35.

Quantitative, time-resolved proteomic analysis by combining bioorthogonal noncanonical amino acid tagging and pulsed stable isotope labeling by amino acids in cell culture.

Bagert JD, Xie YJ, Sweredoski MJ, Qi Y, Hess S, Schuman EM, Tirrell DA.

Mol Cell Proteomics. 2014 May;13(5):1352-8. doi: 10.1074/mcp.M113.031914. Epub 2014 Feb 21.

36.

SnapShot: local protein translation in dendrites.

Tom Dieck S, Hanus C, Schuman EM.

Neuron. 2014 Feb 19;81(4):958-958.e1. doi: 10.1016/j.neuron.2014.02.009. Review. No abstract available.

37.

Molecular biology. mRNA, live and unmasked.

Akbalik G, Schuman EM.

Science. 2014 Jan 24;343(6169):375-6. doi: 10.1126/science.1249623. No abstract available.

PMID:
24458628
38.

Deep sequencing and high-resolution imaging reveal compartment-specific localization of Bdnf mRNA in hippocampal neurons.

Will TJ, Tushev G, Kochen L, Nassim-Assir B, Cajigas IJ, Tom Dieck S, Schuman EM.

Sci Signal. 2013 Dec 17;6(306):rs16. doi: 10.1126/scisignal.2004520.

39.

Role of N-cadherin cis and trans interfaces in the dynamics of adherens junctions in living cells.

Bunse S, Garg S, Junek S, Vogel D, Ansari N, Stelzer EH, Schuman E.

PLoS One. 2013 Dec 2;8(12):e81517. doi: 10.1371/journal.pone.0081517. eCollection 2013.

40.

Alternative polyadenylation and differential expression of Shank mRNAs in the synaptic neuropil.

Epstein I, Tushev G, Will TJ, Vlatkovic I, Cajigas IJ, Schuman EM.

Philos Trans R Soc Lond B Biol Sci. 2013 Dec 2;369(1633):20130137. doi: 10.1098/rstb.2013.0137. Print 2014 Jan 5.

41.

The central dogma decentralized: new perspectives on RNA function and local translation in neurons.

Holt CE, Schuman EM.

Neuron. 2013 Oct 30;80(3):648-57. doi: 10.1016/j.neuron.2013.10.036. Review.

42.

Protein synthesis-dependent associative long-term memory in larval zebrafish.

Hinz FI, Aizenberg M, Tushev G, Schuman EM.

J Neurosci. 2013 Sep 25;33(39):15382-7. doi: 10.1523/JNEUROSCI.0560-13.2013.

43.

Teaching old NCATs new tricks: using non-canonical amino acid tagging to study neuronal plasticity.

Hinz FI, Dieterich DC, Schuman EM.

Curr Opin Chem Biol. 2013 Oct;17(5):738-46. doi: 10.1016/j.cbpa.2013.07.021. Epub 2013 Aug 9. Review.

44.

Proteostasis in complex dendrites.

Hanus C, Schuman EM.

Nat Rev Neurosci. 2013 Sep;14(9):638-48. doi: 10.1038/nrn3546. Epub 2013 Jul 31. Review.

PMID:
23900412
45.

Measures we can take when we're driven to distraction by disturbing circumstances or troublesome people.

Schuman E.

Bull Menninger Clin. 2013 Spring;77(2):178-84. doi: 10.1521/bumc.2013.77.2.178.

PMID:
23697821
46.

Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3.

Disch JS, Evindar G, Chiu CH, Blum CA, Dai H, Jin L, Schuman E, Lind KE, Belyanskaya SL, Deng J, Coppo F, Aquilani L, Graybill TL, Cuozzo JW, Lavu S, Mao C, Vlasuk GP, Perni RB.

J Med Chem. 2013 May 9;56(9):3666-79. doi: 10.1021/jm400204k. Epub 2013 Apr 29.

PMID:
23570514
47.

Axonal translation of β-catenin regulates synaptic vesicle dynamics.

Taylor AM, Wu J, Tai HC, Schuman EM.

J Neurosci. 2013 Mar 27;33(13):5584-9. doi: 10.1523/JNEUROSCI.2944-12.2013.

48.

Mutant methionyl-tRNA synthetase from bacteria enables site-selective N-terminal labeling of proteins expressed in mammalian cells.

Ngo JT, Schuman EM, Tirrell DA.

Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):4992-7. doi: 10.1073/pnas.1216375110. Epub 2013 Mar 11.

49.

Evidence for a common mechanism of SIRT1 regulation by allosteric activators.

Hubbard BP, Gomes AP, Dai H, Li J, Case AW, Considine T, Riera TV, Lee JE, E SY, Lamming DW, Pentelute BL, Schuman ER, Stevens LA, Ling AJ, Armour SM, Michan S, Zhao H, Jiang Y, Sweitzer SM, Blum CA, Disch JS, Ng PY, Howitz KT, Rolo AP, Hamuro Y, Moss J, Perni RB, Ellis JL, Vlasuk GP, Sinclair DA.

Science. 2013 Mar 8;339(6124):1216-9. doi: 10.1126/science.1231097.

50.

Metabolic labeling with noncanonical amino acids and visualization by chemoselective fluorescent tagging.

Tom Dieck S, Müller A, Nehring A, Hinz FI, Bartnik I, Schuman EM, Dieterich DC.

Curr Protoc Cell Biol. 2012 Sep;Chapter 7:Unit7.11. doi: 10.1002/0471143030.cb0711s56.

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