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Genomic exploration of sequential clinical isolates reveals a distinctive molecular signature of persistent Staphylococcus aureus bacteraemia.

Giulieri SG, Baines SL, Guerillot R, Seemann T, Gonçalves da Silva A, Schultz M, Massey RC, Holmes NE, Stinear TP, Howden BP.

Genome Med. 2018 Aug 23;10(1):65. doi: 10.1186/s13073-018-0574-x.


Assays for NAD+-Dependent Reactions and NAD+ Metabolites.

Schultz MB, Lu Y, Braidy N, Sinclair DA.

Methods Mol Biol. 2018;1813:77-90. doi: 10.1007/978-1-4939-8588-3_6.


Infliximab and adalimumab concentrations and anti-drug antibodies in inflammatory bowel disease control using New Zealand assays.

Barclay ML, Karim S, Helms ETJ, Keating PE, Hock B, Stamp LK, Schultz M.

Intern Med J. 2018 Aug 8. doi: 10.1111/imj.14064. [Epub ahead of print]


Plasma sRAGE is independently associated with increased mortality in ARDS: a meta-analysis of individual patient data.

Jabaudon M, Blondonnet R, Pereira B, Cartin-Ceba R, Lichtenstern C, Mauri T, Determann RM, Drabek T, Hubmayr RD, Gajic O, Uhle F, Coppadoro A, Pesenti A, Schultz MJ, Ranieri MV, Brodska H, Mrozek S, Sapin V, Matthay MA, Constantin JM, Calfee CS.

Intensive Care Med. 2018 Jul 26. doi: 10.1007/s00134-018-5327-1. [Epub ahead of print]


Pharmacogenetic neuronal stimulation increases human tau pathology and trans-synaptic spread of tau to distal brain regions in mice.

Schultz MK Jr, Gentzel R, Usenovic M, Gretzula C, Ware C, Parmentier-Batteur S, Schachter JB, Zariwala HA.

Neurobiol Dis. 2018 Oct;118:161-176. doi: 10.1016/j.nbd.2018.07.003. Epub 2018 Jul 7.


Critical care outcomes in resource-limited settings.

Vukoja M, Riviello ED, Schultz MJ.

Curr Opin Crit Care. 2018 Jul 23. doi: 10.1097/MCC.0000000000000528. [Epub ahead of print]


New Surviving Sepsis Campaign guidelines: back to the art of medicine.

Scala R, Schultz M, Bos LDJ, Artigas A.

Eur Respir J. 2018 Jul 11;52(1). pii: 1701818. doi: 10.1183/13993003.01818-2017. Print 2018 Jul. No abstract available.


Prediction of extubation failure in intensive care unit: systematic review of parameters investigated.

Lombardi FS, Cotoia A, Petta R, Schultz M, Cinnella G, Horn J.

Minerva Anestesiol. 2018 Jul 9. doi: 10.23736/S0375-9393.18.12627-7. [Epub ahead of print]


Association between pre-operative biological phenotypes and postoperative pulmonary complications: An unbiased cluster analysis.

Serpa Neto A, Bos LD, Campos PPZA, Hemmes SNT, Bluth T, Calfee CS, Ferner M, Güldner A, Hollmann MW, India I, Kiss T, Laufenberg-Feldmann R, Sprung J, Sulemanji D, Unzueta C, Vidal Melo MF, Weingarten TN, Tuip-de Boer AM, Pelosi P, Gama de Abreu M, Schultz MJ; PROVHILO* and the PROVE** investigators.

Eur J Anaesthesiol. 2018 Sep;35(9):702-709. doi: 10.1097/EJA.0000000000000846.


No association between systemic complement activation and intensive care unit-acquired weakness.

Witteveen E, Wieske L, de Beer FM, Juffermans NP, Verhamme C, Schultz MJ, van Schaik IN, Horn J; BASIC study group.

Ann Transl Med. 2018 Apr;6(7):115. doi: 10.21037/atm.2018.01.30.


A multifaceted individualized pneumoperitoneum strategy for laparoscopic colorectal surgery: a multicenter observational feasibility study.

Diaz-Cambronero O, Flor Lorente B, Mazzinari G, Vila Montañes M, García Gregorio N, Robles Hernandez D, Olmedilla Arnal LE, Argente Navarro MP, Schultz MJ, Errando CL; IPPColLapSe study group.

Surg Endosc. 2018 Jun 27. doi: 10.1007/s00464-018-6305-y. [Epub ahead of print]


Modeling Cell and Tumor-Metastasis Dosimetry with the Particle and Heavy Ion Transport Code System (PHITS) Software for Targeted Alpha-Particle Radionuclide Therapy.

Lee D, Li M, Bednarz B, Schultz MK.

Radiat Res. 2018 Jun 26. doi: 10.1667/RR15081.1. [Epub ahead of print]


The LAS VEGAS risk score for prediction of postoperative pulmonary complications: An observational study.

Neto AS, da Costa LGV, Hemmes SNT, Canet J, Hedenstierna G, Jaber S, Hiesmayr M, Hollmann MW, Mills GH, Vidal Melo MF, Pearse R, Putensen C, Schmid W, Severgnini P, Wrigge H, Gama de Abreu M, Pelosi P, Schultz MJ; LAS VEGAS.

Eur J Anaesthesiol. 2018 Sep;35(9):691-701. doi: 10.1097/EJA.0000000000000845.


Factors associated with physical activity promotion by allied and other non-medical health professionals: A systematic review.

Crisford P, Winzenberg T, Venn A, Schultz M, Aitken D, Cleland V.

Patient Educ Couns. 2018 May 21. pii: S0738-3991(18)30225-8. doi: 10.1016/j.pec.2018.05.011. [Epub ahead of print] Review.


Serious Consequences of Malnutrition and Delirium in Frail Older Patients.

Rosted E, Prokofieva T, Sanders S, Schultz M.

J Nutr Gerontol Geriatr. 2018 Apr-Jun;37(2):105-116. doi: 10.1080/21551197.2018.1470055. Epub 2018 May 24.


Cervical vagus nerve morphometry and vascularity in the context of nerve stimulation - A cadaveric study.

Hammer N, Löffler S, Cakmak YO, Ondruschka B, Planitzer U, Schultz M, Winkler D, Weise D.

Sci Rep. 2018 May 22;8(1):7997. doi: 10.1038/s41598-018-26135-8.


Wolbachia wStri Blocks Zika Virus Growth at Two Independent Stages of Viral Replication.

Schultz MJ, Tan AL, Gray CN, Isern S, Michael SF, Frydman HM, Connor JH.

MBio. 2018 May 22;9(3). pii: e00738-18. doi: 10.1128/mBio.00738-18.


Practice of mechanical ventilation in cardiac arrest patients and effects of targeted temperature management: A substudy of the targeted temperature management trial.

Harmon MBA, van Meenen DMP, van der Veen ALIP, Binnekade JM, Dankiewicz J, Ebner F, Nielsen N, Pelosi P, Schultz MJ, Horn J, Friberg H, Juffermans NP; TTM trial investigators.

Resuscitation. 2018 Aug;129:29-36. doi: 10.1016/j.resuscitation.2018.04.040. Epub 2018 May 12.


RELAx - REstricted versus Liberal positive end-expiratory pressure in patients without ARDS: protocol for a randomized controlled trial.

Algera AG, Pisani L, Bergmans DCJ, den Boer S, de Borgie CAJ, Bosch FH, Bruin K, Cherpanath TG, Determann RM, Dondorp AM, Dongelmans DA, Endeman H, Haringman JJ, Horn J, Juffermans NP, van Meenen DM, van der Meer NJ, Merkus MP, Moeniralam HS, Purmer I, Tuinman PR, Slabbekoorn M, Spronk PE, Vlaar APJ, Gama de Abreu M, Pelosi P, Serpa Neto A, Schultz MJ, Paulus F; RELAx Investigators and the PROVE Network Investigators.

Trials. 2018 May 9;19(1):272. doi: 10.1186/s13063-018-2640-5.


Dynamic field testing of coating chemistry candidates by a rotating disk system.

Nolte KA, Koc J, Barros JM, Hunsucker K, Schultz MP, Swain GW, Rosenhahn A.

Biofouling. 2018 Apr;34(4):398-409. doi: 10.1080/08927014.2018.1459578. Epub 2018 May 8.


A supported education service pilot for returning veterans with posttraumatic stress disorder.

Ellison ML, Reilly ED, Mueller L, Schultz MR, Drebing CE.

Psychol Serv. 2018 May;15(2):200-207. doi: 10.1037/ser0000180.


Treatment with broadly neutralizing influenza antibodies reduces severity of secondary pneumococcal pneumonia in mice.

van Someren Gréve F, van der Sluijs KF, Tuip AM, Schultz MJ, de Jong MD, Juffermans NP.

J Med Virol. 2018 Sep;90(9):1431-1437. doi: 10.1002/jmv.25212. Epub 2018 Jun 12.


Iron metabolism in critically ill patients developing anemia of inflammation: a case control study.

Boshuizen M, Binnekade JM, Nota B, van de Groep K, Cremer OL, Tuinman PR, Horn J, Schultz MJ, van Bruggen R, Juffermans NP; Molecular Diagnosis and Risk Stratification of Sepsis (MARS) Consortium.

Ann Intensive Care. 2018 May 2;8(1):56. doi: 10.1186/s13613-018-0407-5.


Early Prediction of Intensive Care Unit-Acquired Weakness: A Multicenter External Validation Study.

Witteveen E, Wieske L, Sommers J, Spijkstra JJ, de Waard MC, Endeman H, Rijkenberg S, de Ruijter W, Sleeswijk M, Verhamme C, Schultz MJ, van Schaik IN, Horn J.

J Intensive Care Med. 2018 Jan 1:885066618771001. doi: 10.1177/0885066618771001. [Epub ahead of print]


PRactice of VENTilation in Middle-Income Countries (PRoVENT-iMIC): rationale and protocol for a prospective international multicentre observational study in intensive care units in Asia.

Pisani L, Algera AG, Serpa Neto A, Ahsan A, Beane A, Chittawatanarat K, Faiz A, Haniffa R, Hashemian R, Hashmi M, Imad HA, Indraratna K, Iyer S, Kayastha G, Krishna B, Moosa H, Nadjm B, Pattnaik R, Sampath S, Thwaites L, Tun NN, Yunos NM, Grasso S, Paulus F, de Abreu MG, Pelosi P, Dondorp AM, Schultz MJ; PRoVENT–iMIC investigators, MORU and the PROVE network.

BMJ Open. 2018 Apr 28;8(4):e020841. doi: 10.1136/bmjopen-2017-020841.


Previous Use of Antithrombotic Agents Reduces Mortality and Length of Hospital Stay in Patients With High-risk Upper Gastrointestinal Bleeding.

Dunne PDJ, Laursen SB, Laine L, Dalton HR, Ngu JH, Schultz M, Rahman A, Anderloni A, Murray IA, Stanley AJ.

Clin Gastroenterol Hepatol. 2018 Apr 26. pii: S1542-3565(18)30408-7. doi: 10.1016/j.cgh.2018.04.046. [Epub ahead of print]


The fragility of statistically significant findings in randomised controlled anaesthesiology trials: systematic review of the medical literature.

Mazzinari G, Ball L, Serpa Neto A, Errando CL, Dondorp AM, Bos LD, Gama de Abreu M, Pelosi P, Schultz MJ.

Br J Anaesth. 2018 May;120(5):935-941. doi: 10.1016/j.bja.2018.01.012. Epub 2018 Feb 13. Review.


A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications.

Abbott TEF, Fowler AJ, Pelosi P, Gama de Abreu M, Møller AM, Canet J, Creagh-Brown B, Mythen M, Gin T, Lalu MM, Futier E, Grocott MP, Schultz MJ, Pearse RM; StEP-COMPAC Group.

Br J Anaesth. 2018 May;120(5):1066-1079. doi: 10.1016/j.bja.2018.02.007. Epub 2018 Mar 27. Review.


Modulating membrane fluidity corrects Batten disease phenotypes in vitro and in vivo.

Schultz ML, Tecedor L, Lysenko E, Ramachandran S, Stein CS, Davidson BL.

Neurobiol Dis. 2018 Jul;115:182-193. doi: 10.1016/j.nbd.2018.04.010. Epub 2018 Apr 13.


Reply to: high versus low positive end-expiratory pressure for abdominal surgery.

Treschan TA, Gama de Abreu M, Pelosi P, Schultz MJ; PROVE Network Investigators.

Eur J Anaesthesiol. 2018 Jan;35(1):67-68. doi: 10.1097/EJA.0000000000000719. No abstract available.


Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study.

Madotto F, Pham T, Bellani G, Bos LD, Simonis FD, Fan E, Artigas A, Brochard L, Schultz MJ, Laffey JG; LUNG SAFE Investigators and the ESICM Trials Group.

Intensive Care Med. 2018 May;44(5):564-577. doi: 10.1007/s00134-018-5152-6. Epub 2018 Apr 9.


Discovery of New Blood Pressure Phenotypes and Relation to Accuracy of Cuff Devices Used in Daily Clinical Practice.

Picone DS, Schultz MG, Peng X, Black JA, Dwyer N, Roberts-Thomson P, Chen CH, Cheng HM, Pucci G, Wang JG, Sharman JE.

Hypertension. 2018 Jun;71(6):1239-1247. doi: 10.1161/HYPERTENSIONAHA.117.10696. Epub 2018 Apr 9.


Dual Insect specific virus infection limits Arbovirus replication in Aedes mosquito cells.

Schultz MJ, Frydman HM, Connor JH.

Virology. 2018 May;518:406-413. doi: 10.1016/j.virol.2018.03.022. Epub 2018 Apr 3.


Validation of a Host Response Assay, Septicyte™ LAB, for Discriminating Sepsis from SIRS in the ICU.

Miller Iii RR, Lopansri BK, Burke JP, Levy M, Opal S, Rothman RE, D'Alessio FR, Sidhaye VK, Aggarwal NR, Balk R, Greenberg JA, Yoder M, Patel G, Gilbert E, Afshar M, Parada JP, Martin GS, Esper AM, Kempker JA, Narasimhan M, Tsegaye A, Hahn S, Mayo P, van der Poll T, Schultz MJ, Scicluna BP, Klein Klouwenberg P, Rapisarda A, Seldon TA, McHugh LC, Yager TD, Cermelli S, Sampson D, Rothwell V, Newman R, Bhide S, Fox BA, Kirk JT, Navalkar K, Davis RF, Brandon RA, Brandon RB.

Am J Respir Crit Care Med. 2018 Apr 6. doi: 10.1164/rccm.201712-2472OC. [Epub ahead of print]


The cultural expression of spiritual distress in Israel.

Schultz M, Meged-Book T, Mashiach T, Bar-Sela G.

Support Care Cancer. 2018 Sep;26(9):3187-3193. doi: 10.1007/s00520-018-4177-2. Epub 2018 Mar 30.


The 25th birthday and premature death of the open lung approach?-from science, through art, towards precision medicine.

Bein T, Schultz MJ.

J Thorac Dis. 2018 Jan;10(1):135-137. doi: 10.21037/jtd.2017.12.118. No abstract available.


Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging.

Das A, Huang GX, Bonkowski MS, Longchamp A, Li C, Schultz MB, Kim LJ, Osborne B, Joshi S, Lu Y, Treviño-Villarreal JH, Kang MJ, Hung TT, Lee B, Williams EO, Igarashi M, Mitchell JR, Wu LE, Turner N, Arany Z, Guarente L, Sinclair DA.

Cell. 2018 Mar 22;173(1):74-89.e20. doi: 10.1016/j.cell.2018.02.008.


Potentially modifiable respiratory variables contributing to outcome in ICU patients without ARDS: a secondary analysis of PRoVENT.

Simonis FD, Barbas CSV, Artigas-Raventós A, Canet J, Determann RM, Anstey J, Hedenstierna G, Hemmes SNT, Hermans G, Hiesmayr M, Hollmann MW, Jaber S, Martin-Loeches I, Mills GH, Pearse RM, Putensen C, Schmid W, Severgnini P, Smith R, Treschan TA, Tschernko EM, Vidal Melo MF, Wrigge H, de Abreu MG, Pelosi P, Schultz MJ, Neto AS; PRoVENT investigators; PROVE Network investigators.

Ann Intensive Care. 2018 Mar 21;8(1):39. doi: 10.1186/s13613-018-0385-7.


Platelet Toll-like receptor expression and activation induced by lipopolysaccharide and sepsis.

Claushuis TAM, Van Der Veen AIP, Horn J, Schultz MJ, Houtkooper RH, Van 't Veer C, Van Der Poll T.

Platelets. 2018 Mar 12:1-9. doi: 10.1080/09537104.2018.1445841. [Epub ahead of print]


90Y-DOTATOC Dosimetry-Based Personalized Peptide Receptor Radionuclide Therapy.

Menda Y, Madsen MT, O'Dorisio TM, Sunderland J, Watkins LG, Dillon JS, Mott SL, Schultz MK, Zamba GKD, Bushnell DL, O'Dorisio MS.

J Nucl Med. 2018 Mar 9. pii: jnumed.117.202903. doi: 10.2967/jnumed.117.202903. [Epub ahead of print]


The long sepsis journey in low- and middle-income countries begins with a first step...but on which road?

Kwizera A, Baelani I, Mer M, Kissoon N, Schultz MJ, Patterson AJ, Musa N, Farmer JC, Dünser MW; Sepsis in Resource-Limited Settings Workgroup of the Surviving Sepsis Campaign.

Crit Care. 2018 Mar 9;22(1):64. doi: 10.1186/s13054-018-1987-z. No abstract available.


Mobile phones and computer keyboards: unlikely reservoirs of multidrug-resistant organisms in the tertiary intensive care unit.

Smibert OC, Aung AK, Woolnough E, Carter GP, Schultz MB, Howden BP, Seemann T, Spelman D, McGloughlin S, Peleg AY.

J Hosp Infect. 2018 Jul;99(3):295-298. doi: 10.1016/j.jhin.2018.02.013. Epub 2018 Mar 2.


Incorporation of Daily Goals in Daily Care Planning Does Not Shorten Length of Stay in the Intensive Care Unit.

Binnekade JM, Brunsveld-Reinders AH, Arbous MS, Dijkgraaf MGW, Horn J, van der Sloot JAP, Balzereit A, Schultz MJ, Brinkman S, Vroom MB.

Crit Care Nurs Q. 2018 Apr/Jun;41(2):178-185. doi: 10.1097/CNQ.0000000000000197.


Effect of On-Demand vs Routine Nebulization of Acetylcysteine With Salbutamol on Ventilator-Free Days in Intensive Care Unit Patients Receiving Invasive Ventilation: A Randomized Clinical Trial.

van Meenen DMP, van der Hoeven SM, Binnekade JM, de Borgie CAJM, Merkus MP, Bosch FH, Endeman H, Haringman JJ, van der Meer NJM, Moeniralam HS, Slabbekoorn M, Muller MCA, Stilma W, van Silfhout B, Neto AS, Ter Haar HFM, Van Vliet J, Wijnhoven JW, Horn J, Juffermans NP, Pelosi P, Gama de Abreu M, Schultz MJ, Paulus F.

JAMA. 2018 Mar 13;319(10):993-1001. doi: 10.1001/jama.2018.0949.


Full-Field-of-View Time-Harmonic Elastography of the Native Kidney.

Marticorena Garcia SR, Grossmann M, Lang ST, Nguyen Trong M, Schultz M, Guo J, Hamm B, Braun J, Sack I, Tzschätzsch H.

Ultrasound Med Biol. 2018 May;44(5):949-954. doi: 10.1016/j.ultrasmedbio.2018.01.007. Epub 2018 Feb 22.


Validation of a Novel Molecular Host Response Assay to Diagnose Infection in Hospitalized Patients Admitted to the ICU With Acute Respiratory Failure.

Koster-Brouwer ME, Verboom DM, Scicluna BP, van de Groep K, Frencken JF, Janssen D, Schuurman R, Schultz MJ, van der Poll T, Bonten MJM, Cremer OL; MARS Consortium.

Crit Care Med. 2018 Mar;46(3):368-374. doi: 10.1097/CCM.0000000000002735.


Correction to: External confirmation and exploration of the Kigali modification for diagnosing moderate or severe ARDS.

Vercesi V, Pisani L, van Tongeren PSI, Lagrand WK, Leopold SJ, Huson MMA, Henwood PC, Walden A, Smit M, Riviello ED, Pelosi P, Dondorp AM, Schultz MJ; Lung Ultrasound Consortium.

Intensive Care Med. 2018 Mar;44(3):403-404. doi: 10.1007/s00134-018-5098-8.


Variable versus conventional lung protective mechanical ventilation during open abdominal surgery (PROVAR): a randomised controlled trial.

Spieth PM, Güldner A, Uhlig C, Bluth T, Kiss T, Conrad C, Bischlager K, Braune A, Huhle R, Insorsi A, Tarantino F, Ball L, Schultz MJ, Abolmaali N, Koch T, Pelosi P, Gama de Abreu M; PROtective Ventilation (PROVE) Network.

Br J Anaesth. 2018 Mar;120(3):581-591. doi: 10.1016/j.bja.2017.11.078. Epub 2017 Dec 1.


Haemodynamic assessment and support in sepsis and septic shock in resource-limited settings.

Misango D, Pattnaik R, Baker T, Dünser MW, Dondorp AM, Schultz MJ; Global Intensive Care Working Group; of the European Society of Intensive Care Medicine (ESICM) and the Mahidol Oxford Tropical Medicine Research Unit (MORU) in Bangkok, Thailand.

Trans R Soc Trop Med Hyg. 2017 Nov 1;111(11):483-489. doi: 10.1093/trstmh/try007.


Cytotoxic activity and structural features of Ru(II)/phosphine/amino acid complexes.

Dos Santos ER, Graminha AE, Schultz MS, Correia I, Selistre-de-Araújo HS, Corrêa RS, Ellena J, Lacerda EPS, Pessoa JC, Batista AA.

J Inorg Biochem. 2018 May;182:48-60. doi: 10.1016/j.jinorgbio.2017.12.010. Epub 2017 Dec 23.


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