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Items: 1 to 50 of 200

1.

Deviations of the immune cell landscape between healthy liver and hepatocellular carcinoma.

Rohr-Udilova N, Klinglmüller F, Schulte-Hermann R, Stift J, Herac M, Salzmann M, Finotello F, Timelthaler G, Oberhuber G, Pinter M, Reiberger T, Jensen-Jarolim E, Eferl R, Trauner M.

Sci Rep. 2018 Apr 18;8(1):6220. doi: 10.1038/s41598-018-24437-5.

2.

Impact of glutathione peroxidase 4 on cell proliferation, angiogenesis and cytokine production in hepatocellular carcinoma.

Rohr-Udilova N, Bauer E, Timelthaler G, Eferl R, Stolze K, Pinter M, Seif M, Hayden H, Reiberger T, Schulte-Hermann R, Peck-Radosavljevic M, Stoiber D, Trauner M.

Oncotarget. 2018 Jan 22;9(11):10054-10068. doi: 10.18632/oncotarget.24300. eCollection 2018 Feb 9.

3.

Mesenchyme-derived factors enhance preneoplastic growth by non-genotoxic carcinogens in rat liver.

Nejabat M, Riegler T, Reitinger T, Subosits S, Römer M, Eichner J, Bilban M, Zell A, Huber WW, Schulte-Hermann R, Grasl-Kraupp B.

Arch Toxicol. 2018 Feb;92(2):953-966. doi: 10.1007/s00204-017-2080-0. Epub 2017 Dec 21.

4.

The European Registered Toxicologist (ERT): Current status and prospects for advancement.

Wilks MF, Blaauboer BJ, Schulte-Hermann R, Wallace HM, Galli CL, Haag-Grönlund M, Matović V, Teixeira JP, Zilliacus J, Basaran N, Bonefeld-Jørgensen EC, Bourrinet P, Brueller W, Claude N, Miranda JP, Gundert-Remy U, Håkansson H, Kovatsi L, Liesivuori J, Lindeman B, Lison D, Leconte I, Martínez-López E, Murias M, Michel C, Scheepers PTJ, Stanley L, Tsatsakis A.

Toxicol Lett. 2016 Sep 30;259:151-155. doi: 10.1016/j.toxlet.2016.06.014. Epub 2016 Jun 22.

PMID:
27343956
5.

Proinflammatory mesenchymal effects of the non-genotoxic hepatocarcinogen phenobarbital: a novel mechanism of antiapoptosis and tumor promotion.

Riegler T, Nejabat M, Eichner J, Stiebellehner M, Subosits S, Bilban M, Zell A, Huber WW, Schulte-Hermann R, Grasl-Kraupp B.

Carcinogenesis. 2015 Dec;36(12):1521-30. doi: 10.1093/carcin/bgv135. Epub 2015 Sep 16.

PMID:
26378027
6.

Superoxide deficiency attenuates promotion of hepatocarcinogenesis by cytotoxicity in NADPH oxidase knockout mice.

Parzefall W, Freiler C, Lorenz O, Koudelka H, Riegler T, Nejabat M, Kainzbauer E, Grasl-Kraupp B, Schulte-Hermann R.

Arch Toxicol. 2015 Aug;89(8):1383-93. doi: 10.1007/s00204-014-1298-3. Epub 2014 Sep 3.

PMID:
25182417
7.

Fibroblast growth factor receptor 4: a putative key driver for the aggressive phenotype of hepatocellular carcinoma.

Gauglhofer C, Paur J, Schrottmaier WC, Wingelhofer B, Huber D, Naegelen I, Pirker C, Mohr T, Heinzle C, Holzmann K, Marian B, Schulte-Hermann R, Berger W, Krupitza G, Grusch M, Grasl-Kraupp B.

Carcinogenesis. 2014 Oct;35(10):2331-8. doi: 10.1093/carcin/bgu151. Epub 2014 Jul 16.

PMID:
25031272
8.

Food-derived peroxidized fatty acids may trigger hepatic inflammation: a novel hypothesis to explain steatohepatitis.

Böhm T, Berger H, Nejabat M, Riegler T, Kellner F, Kuttke M, Sagmeister S, Bazanella M, Stolze K, Daryabeigi A, Bintner N, Murkovic M, Wagner KH, Schulte-Hermann R, Rohr-Udilova N, Huber W, Grasl-Kraupp B.

J Hepatol. 2013 Sep;59(3):563-70. doi: 10.1016/j.jhep.2013.04.025. Epub 2013 May 9.

PMID:
23665282
9.

The major vault protein mediates resistance to epidermal growth factor receptor inhibition in human hepatoma cells.

Losert A, Lötsch D, Lackner A, Koppensteiner H, Peter-Vörösmarty B, Steiner E, Holzmann K, Grunt T, Schmid K, Marian B, Grasl-Kraupp B, Schulte-Hermann R, Krupitza G, Berger W, Grusch M.

Cancer Lett. 2012 Jun 28;319(2):164-172. doi: 10.1016/j.canlet.2012.01.002. Epub 2012 Jan 17.

PMID:
22261339
10.

Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma.

Rohr-Udilova N, Sieghart W, Eferl R, Stoiber D, Björkhem-Bergman L, Eriksson LC, Stolze K, Hayden H, Keppler B, Sagmeister S, Grasl-Kraupp B, Schulte-Hermann R, Peck-Radosavljevic M.

Hepatology. 2012 Apr;55(4):1112-21. doi: 10.1002/hep.24808.

PMID:
22105228
11.

Inhibin/activin expression in human and rodent liver: subunits α and βB as new players in human hepatocellular carcinoma?

Frost K, Seir K, Lackner A, Grusch M, Grasl-Kraupp B, Schulte-Hermann R, Rodgarkia-Dara C.

Br J Cancer. 2011 Apr 12;104(8):1303-12. doi: 10.1038/bjc.2011.53. Epub 2011 Mar 15.

12.

Up-regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis.

Gauglhofer C, Sagmeister S, Schrottmaier W, Fischer C, Rodgarkia-Dara C, Mohr T, Stättner S, Bichler C, Kandioler D, Wrba F, Schulte-Hermann R, Holzmann K, Grusch M, Marian B, Berger W, Grasl-Kraupp B.

Hepatology. 2011 Mar;53(3):854-64. doi: 10.1002/hep.24099. Epub 2011 Feb 11.

PMID:
21319186
13.

Proteomics reveals acute pro-inflammatory and protective responses in rat Kupffer cells and hepatocytes after chemical initiation of liver cancer and after LPS and IL-6.

Lorenz O, Parzefall W, Kainzbauer E, Wimmer H, Grasl-Kraupp B, Gerner C, Schulte-Hermann R.

Proteomics Clin Appl. 2009 Aug;3(8):947-67. doi: 10.1002/prca.200800173.

PMID:
21136998
14.

NORE1B is a putative tumor suppressor in hepatocarcinogenesis and may act via RASSF1A.

Macheiner D, Gauglhofer C, Rodgarkia-Dara C, Grusch M, Brachner A, Bichler C, Kandioler D, Sutterlüty H, Mikulits W, Schulte-Hermann R, Grasl-Kraupp B.

Cancer Res. 2009 Jan 1;69(1):235-42. doi: 10.1158/0008-5472.CAN-08-2144.

15.

Inhalative exposure to vanadium pentoxide causes DNA damage in workers: results of a multiple end point study.

Ehrlich VA, Nersesyan AK, Atefie K, Hoelzl C, Ferk F, Bichler J, Valic E, Schaffer A, Schulte-Hermann R, Fenech M, Wagner KH, Knasmüller S.

Environ Health Perspect. 2008 Dec;116(12):1689-93. doi: 10.1289/ehp.11438. Epub 2008 Jul 31. Erratum in: Environ Health Perspect. 2009 Jan;117(1):A15. Atefie, Kambis [added].

16.

HB-EGF is a paracrine growth stimulator for early tumor prestages in inflammation-associated hepatocarcinogenesis.

Sagmeister S, Drucker C, Losert A, Grusch M, Daryabeigi A, Parzefall W, Rohr-Udilova N, Bichler C, Smedsrød B, Kandioler D, Grünberger T, Wrba F, Schulte-Hermann R, Grasl-Kraupp B.

J Hepatol. 2008 Dec;49(6):955-64. doi: 10.1016/j.jhep.2008.06.031. Epub 2008 Oct 7.

PMID:
18929421
17.

Use of four new human-derived liver-cell lines for the detection of genotoxic compounds in the single-cell gel electrophoresis (SCGE) assay.

Winter HK, Ehrlich VA, Grusch M, Lackner A, Schulte-Hermann R, Grasl-Kraupp B, Mikulits W, Knasmüller S.

Mutat Res. 2008 Dec 8;657(2):133-9. doi: 10.1016/j.mrgentox.2008.08.012. Epub 2008 Aug 26.

PMID:
18790080
18.

Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment.

Eaton DL, Daroff RB, Autrup H, Bridges J, Buffler P, Costa LG, Coyle J, McKhann G, Mobley WC, Nadel L, Neubert D, Schulte-Hermann R, Spencer PS.

Crit Rev Toxicol. 2008;38 Suppl 2:1-125. doi: 10.1080/10408440802272158 . Review.

PMID:
18726789
19.

Cell death and autophagy: cytokines, drugs, and nutritional factors.

Bursch W, Karwan A, Mayer M, Dornetshuber J, Fröhwein U, Schulte-Hermann R, Fazi B, Di Sano F, Piredda L, Piacentini M, Petrovski G, Fésüs L, Gerner C.

Toxicology. 2008 Dec 30;254(3):147-57. doi: 10.1016/j.tox.2008.07.048. Epub 2008 Jul 23. Review.

PMID:
18694801
20.

New cellular tools reveal complex epithelial-mesenchymal interactions in hepatocarcinogenesis.

Sagmeister S, Eisenbauer M, Pirker C, Mohr T, Holzmann K, Zwickl H, Bichler C, Kandioler D, Wrba F, Mikulits W, Gerner C, Shehata M, Majdic O, Streubel B, Berger W, Micksche M, Zatloukal K, Schulte-Hermann R, Grasl-Kraupp B.

Br J Cancer. 2008 Jul 8;99(1):151-9. doi: 10.1038/sj.bjc.6604440.

21.

Activins and activin antagonists in hepatocellular carcinoma.

Deli A, Kreidl E, Santifaller S, Trotter B, Seir K, Berger W, Schulte-Hermann R, Rodgarkia-Dara C, Grusch M.

World J Gastroenterol. 2008 Mar 21;14(11):1699-709. Review.

22.

Lipid hydroperoxides from processed dietary oils enhance growth of hepatocarcinoma cells.

Rohr-Udilova NV, Stolze K, Sagmeister S, Nohl H, Schulte-Hermann R, Grasl-Kraupp B.

Mol Nutr Food Res. 2008 Mar;52(3):352-9. doi: 10.1002/mnfr.200700149.

PMID:
18293301
23.

Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver.

Huber WW, Rossmanith W, Grusch M, Haslinger E, Prustomersky S, Peter-Vörösmarty B, Parzefall W, Scharf G, Schulte-Hermann R.

Food Chem Toxicol. 2008 Apr;46(4):1230-8. Epub 2007 Sep 25.

PMID:
17983700
24.

Cytotoxicity of the novel spin trapping compound 5-ethoxycarbonyl-3,5-dimethyl-pyrroline N-oxide (3,5-EDPO) and its derivatives.

Rohr-Udilova N, Stolze K, Sagmeister S, Parzefall W, Marian B, Nohl H, Schulte-Hermann R, Grasl-Kraupp B.

Bioorg Med Chem Lett. 2007 Oct 15;17(20):5698-703. Epub 2007 Aug 19.

PMID:
17804223
25.

Coffee consumption protects human lymphocytes against oxidative and 3-amino-1-methyl-5H-pyrido[4,3-b]indole acetate (Trp-P-2) induced DNA-damage: results of an experimental study with human volunteers.

Bichler J, Cavin C, Simic T, Chakraborty A, Ferk F, Hoelzl C, Schulte-Hermann R, Kundi M, Haidinger G, Angelis K, Knasmüller S.

Food Chem Toxicol. 2007 Aug;45(8):1428-36. Epub 2007 Feb 12.

PMID:
17376579
26.

Critical review: nicotine for the fetus, the infant and the adolescent?

Ginzel KH, Maritz GS, Marks DF, Neuberger M, Pauly JR, Polito JR, Schulte-Hermann R, Slotkin TA.

J Health Psychol. 2007 Mar;12(2):215-24. Review.

PMID:
17284486
27.

Divide and conquer: rat liver tissue proteomics based on the analysis of purified constituents.

Teufelhofer O, Parzefall W, Elbling L, Kainzbauer E, Grasl-Kraupp B, Zielinski C, Schulte-Hermann R, Gerner C.

Electrophoresis. 2006 Oct;27(20):4112-20.

PMID:
17054093
28.

Effect of staining procedures on the results of micronucleus assays with exfoliated oral mucosa cells.

Nersesyan A, Kundi M, Atefie K, Schulte-Hermann R, Knasmüller S.

Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):1835-40.

29.

The activin axis in liver biology and disease.

Rodgarkia-Dara C, Vejda S, Erlach N, Losert A, Bursch W, Berger W, Schulte-Hermann R, Grusch M.

Mutat Res. 2006 Nov-Dec;613(2-3):123-37. Epub 2006 Sep 25. Review.

PMID:
16997617
30.

Deregulation of the activin/follistatin system in hepatocarcinogenesis.

Grusch M, Drucker C, Peter-Vörösmarty B, Erlach N, Lackner A, Losert A, Macheiner D, Schneider WJ, Hermann M, Groome NP, Parzefall W, Berger W, Grasl-Kraupp B, Schulte-Hermann R.

J Hepatol. 2006 Nov;45(5):673-80. Epub 2006 Jul 28.

PMID:
16935389
31.

Ubiquinol and the papaverine derivative caroverine prevent the expression of tumour- promoting factors in adenoma and carcinoma colon cancer cells induced by dietary fat.

Nohl H, Rohr-Udilova N, Gille L, Bieberschulte W, Jurek D, Marian B, Schulte-Hermann R.

Biofactors. 2005;25(1-4):87-95.

PMID:
16873933
32.

Monitoring viral decontamination procedures with green fluorescent protein-expressing adenovirus.

Losert A, Mauritz I, Erlach N, Herbacek I, Schulte-Hermann R, Holzmann K, Grusch M.

Anal Biochem. 2006 Aug 15;355(2):310-2. Epub 2006 May 4. No abstract available.

PMID:
16712764
33.

Dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA), two naturally occurring benzoxazinones contained in sprouts of Gramineae are potent aneugens in human-derived liver cells (HepG2).

Buchmann CA, Nersesyan A, Kopp B, Schauberger D, Darroudi F, Grummt T, Krupitza G, Kundi M, Schulte-Hermann R, Knasmueller S.

Cancer Lett. 2007 Feb 8;246(1-2):290-9. Epub 2006 Apr 27.

PMID:
16644106
34.

NORE1B, a candidate tumor suppressor, is epigenetically silenced in human hepatocellular carcinoma.

Macheiner D, Heller G, Kappel S, Bichler C, Stättner S, Ziegler B, Kandioler D, Wrba F, Schulte-Hermann R, Zöchbauer-Müller S, Grasl-Kraupp B.

J Hepatol. 2006 Jul;45(1):81-9. Epub 2006 Feb 7.

PMID:
16516329
35.

Analysis of reproductive toxicity and classification of glufosinate-ammonium.

Schulte-Hermann R, Wogan GN, Berry C, Brown NA, Czeizel A, Giavini E, Holmes LB, Kroes R, Nau H, Neubert D, Oesch F, Ott T, Pelkonen O, Robert-Gnansia E, Sullivan FM.

Regul Toxicol Pharmacol. 2006 Apr;44(3 Suppl 1):S1-76. Epub 2006 Feb 28.

PMID:
16510221
36.

Toxicological comments to the discussion about REACH.

Greim H, Arand M, Autrup H, Bolt HM, Bridges J, Dybing E, Glomot R, Foa V, Schulte-Hermann R.

Arch Toxicol. 2006 Mar;80(3):121-4. Epub 2006 Jan 13.

PMID:
16411136
37.

Non-parenchymal liver cells support the growth advantage in the first stages of hepatocarcinogenesis.

Drucker C, Parzefall W, Teufelhofer O, Grusch M, Ellinger A, Schulte-Hermann R, Grasl-Kraupp B.

Carcinogenesis. 2006 Jan;27(1):152-61. Epub 2005 Aug 4.

PMID:
16081514
38.

A novel technique to specifically analyze the secretome of cells and tissues.

Zwickl H, Traxler E, Staettner S, Parzefall W, Grasl-Kraupp B, Karner J, Schulte-Hermann R, Gerner C.

Electrophoresis. 2005 Jul;26(14):2779-85.

PMID:
15966010
39.

Green tea extract and (-)-epigallocatechin-3-gallate, the major tea catechin, exert oxidant but lack antioxidant activities.

Elbling L, Weiss RM, Teufelhofer O, Uhl M, Knasmueller S, Schulte-Hermann R, Berger W, Micksche M.

FASEB J. 2005 May;19(7):807-9. Epub 2005 Feb 28.

PMID:
15738004
40.

No increase of apoptosis in regressing mouse liver after withdrawal of growth stimuli or food restriction.

Bursch W, Wastl U, Hufnagl K, Schulte-Hermann R.

Toxicol Sci. 2005 May;85(1):507-14. Epub 2005 Feb 23.

PMID:
15728705
41.

Apoptosis in stages of mouse hepatocarcinogenesis: failure to counterbalance cell proliferation and to account for strain differences in tumor susceptibility.

Bursch W, Chabicovsky M, Wastl U, Grasl-Kraupp B, Bukowska K, Taper H, Schulte-Hermann R.

Toxicol Sci. 2005 May;85(1):515-29. Epub 2005 Feb 23.

PMID:
15728704
42.

Integration of Ras subeffector signaling in TGF-beta mediated late stage hepatocarcinogenesis.

Fischer AN, Herrera B, Mikula M, Proell V, Fuchs E, Gotzmann J, Schulte-Hermann R, Beug H, Mikulits W.

Carcinogenesis. 2005 May;26(5):931-42. Epub 2005 Feb 10.

PMID:
15705598
43.

Inherent growth advantage of (pre)malignant hepatocytes associated with nuclear translocation of pro-transforming growth factor alpha.

Schausberger E, Hufnagl K, Parzefall W, Gerner C, Kandioler-Eckersberger D, Wrba F, Klimpfinger M, Schulte-Hermann R, Grasl-Kraupp B.

Br J Cancer. 2004 Nov 29;91(11):1955-63.

44.

Dietary lipid hydroperoxides induce expression of vascular endothelial growth factor (VEGF) in human colorectal tumor cells.

Jurek D, Udilova N, Jozkowicz A, Nohl H, Marian B, Schulte-Hermann R.

FASEB J. 2005 Jan;19(1):97-9. Epub 2004 Nov 2.

PMID:
15522906
45.

Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: studies on NADPH oxidase knockout mice.

Teufelhofer O, Parzefall W, Kainzbauer E, Ferk F, Freiler C, Knasmüller S, Elbling L, Thurman R, Schulte-Hermann R.

Carcinogenesis. 2005 Feb;26(2):319-29. Epub 2004 Oct 28.

PMID:
15513930
46.

Role of apoptosis for mouse liver growth regulation and tumor promotion: comparative analysis of mice with high (C3H/He) and low (C57Bl/6J) cancer susceptibility.

Bursch W, Grasl-Kraupp B, Wastl U, Hufnagl K, Chabicovsky M, Taper H, Schulte-Hermann R.

Toxicol Lett. 2004 Apr 1;149(1-3):25-35. Review.

PMID:
15093245
47.

Multiple chromosomal abnormalities in human liver (pre)neoplasia.

Raidl M, Pirker C, Schulte-Hermann R, Aubele M, Kandioler-Eckersberger D, Wrba F, Micksche M, Berger W, Grasl-Kraupp B.

J Hepatol. 2004 Apr;40(4):660-8.

PMID:
15030983
48.

Immortalized p19ARF null hepatocytes restore liver injury and generate hepatic progenitors after transplantation.

Mikula M, Fuchs E, Huber H, Beug H, Schulte-Hermann R, Mikulits W.

Hepatology. 2004 Mar;39(3):628-34.

PMID:
14999681
49.

Immunohistochemical detection of activated caspases in apoptotic hepatocytes in rat liver.

Eckle VS, Buchmann A, Bursch W, Schulte-Hermann R, Schwarz M.

Toxicol Pathol. 2004 Jan-Feb;32(1):9-15.

PMID:
14713542
50.

Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis.

Gotzmann J, Mikula M, Eger A, Schulte-Hermann R, Foisner R, Beug H, Mikulits W.

Mutat Res. 2004 Jan;566(1):9-20. Review.

PMID:
14706509

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