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Items: 1 to 50 of 1175

1.

Enhancing lentiviral transduction to generate melanoma-specific human T cells for cancer immunotherapy.

Simon B, Harrer DC, Thirion C, Schuler-Thurner B, Schuler G, Uslu U.

J Immunol Methods. 2019 Jun 14. pii: S0022-1759(19)30172-3. doi: 10.1016/j.jim.2019.06.015. [Epub ahead of print]

PMID:
31207210
2.

CSPG4-Specific CAR T Cells for High-Risk Childhood B Cell Precursor Leukemia.

Harrer DC, Schuler G, Dörrie J, Schaft N.

Int J Mol Sci. 2019 Jun 5;20(11). pii: E2764. doi: 10.3390/ijms20112764.

3.

Do ovarian steroid hormones control the resumption of embryonic growth following the period of diapause in roe deer (Capreolus capreolus)?

Drews B, Rudolf Vegas A, van der Weijden VA, Milojevic V, Hankele AK, Schuler G, Ulbrich SE.

Reprod Biol. 2019 May 27. pii: S1642-431X(18)30205-5. doi: 10.1016/j.repbio.2019.04.003. [Epub ahead of print]

4.

Arming T Cells with a gp100-Specific TCR and a CSPG4-Specific CAR Using Combined DNA- and RNA-Based Receptor Transfer.

Simon B, Harrer DC, Schuler-Thurner B, Schuler G, Uslu U.

Cancers (Basel). 2019 May 20;11(5). pii: E696. doi: 10.3390/cancers11050696.

5.

Checkpoint inhibitor-induced eosinophilic fasciitis following high eosinophilia associated with complete response.

Toussaint F, Hammon M, Erdmann M, Moreira A, Kirchberger MC, Schuler G, Schett G, Heinzerling L.

Rheumatology (Oxford). 2019 May 5. pii: kez164. doi: 10.1093/rheumatology/kez164. [Epub ahead of print] No abstract available.

PMID:
31056673
6.

Characterization of tanning behavior assessed via online survey: Attitudes, habits, and preventive measures with focus on sunscreen use.

Schneiderbanger CK, Schuler G, Heinzerling L, Kirchberger MC.

Photodermatol Photoimmunol Photomed. 2019 Mar 10. doi: 10.1111/phpp.12465. [Epub ahead of print]

PMID:
30854722
7.

Innate extracellular vesicles from melanoma patients suppress β-catenin in tumor cells by miRNA-34a.

Lee JH, Dindorf J, Eberhardt M, Lai X, Ostalecki C, Koliha N, Gross S, Blume K, Bruns H, Wild S, Schuler G, Vera J, Baur AS.

Life Sci Alliance. 2019 Mar 7;2(2). pii: e201800205. doi: 10.26508/lsa.201800205. Print 2019 Apr.

8.

Eosinophil-cationic protein - a novel liquid prognostic biomarker in melanoma.

Krückel A, Moreira A, Fröhlich W, Schuler G, Heinzerling L.

BMC Cancer. 2019 Mar 7;19(1):207. doi: 10.1186/s12885-019-5384-z.

9.

Detection and Characterization of Circulating Tumor Cells in Patients with Merkel Cell Carcinoma.

Riethdorf S, Hildebrandt L, Heinzerling L, Heitzer E, Fischer N, Bergmann S, Mauermann O, Waldispühl-Geigl J, Coith C, Schön G, Peine S, Schuler G, Speicher MR, Moll I, Pantel K.

Clin Chem. 2019 Mar;65(3):462-472. doi: 10.1373/clinchem.2018.297028. Epub 2019 Jan 9.

PMID:
30626636
10.

Extracellular vesicles from mature dendritic cells (DC) differentiate monocytes into immature DC.

Schierer S, Ostalecki C, Zinser E, Lamprecht R, Plosnita B, Stich L, Dörrie J, Lutz MB, Schuler G, Baur AS.

Life Sci Alliance. 2018 Dec 3;1(6):e201800093. doi: 10.26508/lsa.201800093. eCollection 2018 Dec.

11.

Myositis and neuromuscular side-effects induced by immune checkpoint inhibitors.

Moreira A, Loquai C, Pföhler C, Kähler KC, Knauss S, Heppt MV, Gutzmer R, Dimitriou F, Meier F, Mitzel-Rink H, Schuler G, Terheyden P, Thoms KM, Türk M, Dummer R, Zimmer L, Schröder R, Heinzerling L.

Eur J Cancer. 2019 Jan;106:12-23. doi: 10.1016/j.ejca.2018.09.033. Epub 2018 Nov 17.

PMID:
30453170
12.

Phylogeny and Classification of Novel Diversity in Sainouroidea (Cercozoa, Rhizaria) Sheds Light on a Highly Diverse and Divergent Clade.

Schuler GA, Tice AK, Pearce RA, Foreman E, Stone J, Gammill S, Willson JD, Reading C, Silberman JD, Brown MW.

Protist. 2018 Dec;169(6):853-874. doi: 10.1016/j.protis.2018.08.002. Epub 2018 Aug 22.

PMID:
30415103
13.

Risk Factors for Regional and Systemic Metastases in Patients with Sentinel Lymph Node-negative Melanoma.

Erdmann M, Sigler D, Uslu U, Göhl J, Grützmann R, Schuler G, Schellerer V.

Anticancer Res. 2018 Nov;38(11):6571-6577. doi: 10.21873/anticanres.13024.

PMID:
30396988
14.

Bovine Fetal Placenta During Pregnancy and the Postpartum Period.

Botta C, Pellegrini G, Hässig M, Pesch T, Prähauser B, Wunderlin S, Guscetti F, Schneeberger M, Schmitt S, Basso W, Hilbe M, Schuler G, Borel N.

Vet Pathol. 2019 Mar;56(2):248-258. doi: 10.1177/0300985818806453. Epub 2018 Oct 24.

PMID:
30355149
15.

Automated closed-system manufacturing of human monocyte-derived dendritic cells for cancer immunotherapy.

Erdmann M, Uslu U, Wiesinger M, Brüning M, Altmann T, Strasser E, Schuler G, Schuler-Thurner B.

J Immunol Methods. 2018 Dec;463:89-96. doi: 10.1016/j.jim.2018.09.012. Epub 2018 Sep 25.

PMID:
30266448
16.

Senescence markers: Predictive for response to checkpoint inhibitors.

Moreira A, Gross S, Kirchberger MC, Erdmann M, Schuler G, Heinzerling L.

Int J Cancer. 2019 Mar 1;144(5):1147-1150. doi: 10.1002/ijc.31763. Epub 2018 Dec 4.

PMID:
30151962
17.

The Generation of CAR-Transfected Natural Killer T Cells for the Immunotherapy of Melanoma.

Simon B, Wiesinger M, März J, Wistuba-Hamprecht K, Weide B, Schuler-Thurner B, Schuler G, Dörrie J, Uslu U.

Int J Mol Sci. 2018 Aug 11;19(8). pii: E2365. doi: 10.3390/ijms19082365.

18.

Mild Hypothermia in Cardiogenic Shock Complicating Myocardial Infarction.

Fuernau G, Beck J, Desch S, Eitel I, Jung C, Erbs S, Mangner N, Lurz P, Fengler K, Jobs A, Vonthein R, de Waha-Thiele S, Sandri M, Schuler G, Thiele H.

Circulation. 2019 Jan 22;139(4):448-457. doi: 10.1161/CIRCULATIONAHA.117.032722.

PMID:
30026282
19.

Real world experience in low-dose ipilimumab in combination with PD-1 blockade in advanced melanoma patients.

Kirchberger MC, Moreira A, Erdmann M, Schuler G, Heinzerling L.

Oncotarget. 2018 Jun 22;9(48):28903-28909. doi: 10.18632/oncotarget.25627. eCollection 2018 Jun 22.

20.

Gender-dependent association of diabetes mellitus with mortality in patients undergoing transcatheter aortic valve replacement.

Linke A, Schlotter F, Haussig S, Woitek FJ, Stachel G, Adam J, Höllriegel R, Lindner A, Mohr FW, Schuler G, Kiefer P, Leontyev S, Thiele H, Borger MA, Holzhey D, Mangner N.

Clin Res Cardiol. 2019 Jan;108(1):39-47. doi: 10.1007/s00392-018-1309-0. Epub 2018 Jun 25.

PMID:
29943273
21.

Description of Armaparvus languidus n. gen. n. sp. Confirms Ultrastructural Unity of Cutosea (Amoebozoa, Evosea).

Schuler GA, Brown MW.

J Eukaryot Microbiol. 2019 Jan;66(1):158-166. doi: 10.1111/jeu.12640. Epub 2018 Jun 19.

PMID:
29858563
22.

MEK inhibition may increase survival of NRAS-mutated melanoma patients treated with checkpoint blockade: Results of a retrospective multicentre analysis of 364 patients.

Kirchberger MC, Ugurel S, Mangana J, Heppt MV, Eigentler TK, Berking C, Schadendorf D, Schuler G, Dummer R, Heinzerling L.

Eur J Cancer. 2018 Jul;98:10-16. doi: 10.1016/j.ejca.2018.04.010. Epub 2018 May 26.

PMID:
29843107
23.

The siRNA-mediated downregulation of PD-1 alone or simultaneously with CTLA-4 shows enhanced in vitro CAR-T-cell functionality for further clinical development towards the potential use in immunotherapy of melanoma.

Simon B, Harrer DC, Schuler-Thurner B, Schaft N, Schuler G, Dörrie J, Uslu U.

Exp Dermatol. 2018 Jul;27(7):769-778. doi: 10.1111/exd.13678.

PMID:
29704887
24.

Predictors of Mortality and Symptomatic Outcome of Patients With Low-Flow Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement.

Mangner N, Stachel G, Woitek F, Haussig S, Schlotter F, Höllriegel R, Adam J, Lindner A, Mohr FW, Schuler G, Kiefer P, Leontyev S, Borger MA, Thiele H, Holzhey D, Linke A.

J Am Heart Assoc. 2018 Apr 13;7(8). pii: e007977. doi: 10.1161/JAHA.117.007977.

25.

Transcatheter treatment of tricuspid regurgitation using edge-to-edge repair: procedural results, clinical implications and predictors of success.

Lurz P, Besler C, Noack T, Forner AF, Bevilacqua C, Seeburger J, Rommel KP, Blazek S, Hartung P, Zimmer M, Mohr F, Schuler G, Linke A, Ender J, Thiele H.

EuroIntervention. 2018 Jun 8;14(3):e290-e297. doi: 10.4244/EIJ-D-17-01091.

26.

Effective anti-programmed death-1 therapy in a SUFU-mutated patient with Gorlin-Goltz syndrome.

Moreira A, Kirchberger MC, Toussaint F, Erdmann M, Schuler G, Heinzerling L.

Br J Dermatol. 2018 Sep;179(3):747-749. doi: 10.1111/bjd.16607. Epub 2018 Jun 26.

PMID:
29603722
27.

SULFATION PATHWAYS: Expression of SULT2A1, SULT2B1 and HSD3B1 in the porcine testis and epididymis.

Zimmer B, Tenbusch L, Klymiuk MC, Dezhkam Y, Schuler G.

J Mol Endocrinol. 2018 Aug;61(2):M41-M55. doi: 10.1530/JME-17-0277. Epub 2018 Mar 27.

PMID:
29588428
28.

SULFATION PATHWAYS: Formation and hydrolysis of sulfonated estrogens in the porcine testis and epididymis.

Schuler G, Dezhkam Y, Tenbusch L, Klymiuk MC, Zimmer B, Hoffmann B.

J Mol Endocrinol. 2018 Aug;61(2):M13-M25. doi: 10.1530/JME-17-0245. Epub 2018 Feb 21.

PMID:
29467139
29.

Load-Independent Systolic and Diastolic Right Ventricular Function in Heart Failure With Preserved Ejection Fraction as Assessed by Resting and Handgrip Exercise Pressure-Volume Loops.

Rommel KP, von Roeder M, Oberueck C, Latuscynski K, Besler C, Blazek S, Stiermaier T, Fengler K, Adams V, Sandri M, Linke A, Schuler G, Thiele H, Lurz P.

Circ Heart Fail. 2018 Feb;11(2):e004121. doi: 10.1161/CIRCHEARTFAILURE.117.004121.

PMID:
29449367
30.

Clinical outcome of concomitant vs interrupted BRAF inhibitor therapy during radiotherapy in melanoma patients.

Hecht M, Meier F, Zimmer L, Polat B, Loquai C, Weishaupt C, Forschner A, Gutzmer R, Utikal JS, Goldinger SM, Geier M, Hassel JC, Balermpas P, Kiecker F, Rauschenberg R, Dietrich U, Clemens P, Berking C, Grabenbauer G, Schadendorf D, Grabbe S, Schuler G, Fietkau R, Distel LV, Heinzerling L.

Br J Cancer. 2018 Mar 20;118(6):785-792. doi: 10.1038/bjc.2017.489. Epub 2018 Feb 13.

31.

BRAF and MEK Inhibitors Influence the Function of Reprogrammed T Cells: Consequences for Adoptive T-Cell Therapy.

Dörrie J, Babalija L, Hoyer S, Gerer KF, Schuler G, Heinzerling L, Schaft N.

Int J Mol Sci. 2018 Jan 18;19(1). pii: E289. doi: 10.3390/ijms19010289.

32.

Concealed complete response in melanoma patients under therapy with immune checkpoint inhibitors: two case reports.

Schliep S, Agaimy A, Cavallaro A, Kiesewetter F, Schuler G, Heinzerling L.

J Immunother Cancer. 2018 Jan 15;6(1):2. doi: 10.1186/s40425-017-0309-3.

33.

Occurrence of sulfonated steroids and ovarian expression of steroid sulfatase and SULT1E1 in cyclic cows.

Blaschka C, Schuler G, Sánchez-Guijo A, Zimmer B, Feller S, Kotarski F, Wudy SA, Wrenzycki C.

J Steroid Biochem Mol Biol. 2018 May;179:79-87. doi: 10.1016/j.jsbmb.2017.12.010. Epub 2017 Dec 17.

PMID:
29262378
34.

Das Interesse an Solarien und Sonnenschutz im deutschsprachigen Raum.

Kirchberger MC, Kirchberger LF, Eigentler TK, Reinhard R, Berking C, Schuler G, Heinzerling L, Heppt MV.

J Dtsch Dermatol Ges. 2017 Dec;15(12):1192-1198. doi: 10.1111/ddg.13380_g. No abstract available.

PMID:
29228492
35.

Can checkpoint inhibitor therapy improve response to chemotherapy?

Kirchberger MC, Schilling B, Haferkamp S, Bosserhoff A, Schuler G, Heinzerling L.

J Cancer Res Clin Oncol. 2018 Jan;144(1):183-185. doi: 10.1007/s00432-017-2546-8. Epub 2017 Nov 24. No abstract available.

PMID:
29177557
36.

Impact of active cancer disease on the outcome of patients undergoing transcatheter aortic valve replacement.

Mangner N, Woitek FJ, Haussig S, Holzhey D, Stachel G, Schlotter F, Höllriegel R, Mohr FW, Schuler G, Linke A.

J Interv Cardiol. 2018 Apr;31(2):188-196. doi: 10.1111/joic.12458. Epub 2017 Nov 22.

PMID:
29166702
37.

Interest in tanning beds and sunscreen in German-speaking countries.

Kirchberger MC, Kirchberger LF, Eigentler TK, Reinhard R, Berking C, Schuler G, Heinzerling L, Heppt MV.

J Dtsch Dermatol Ges. 2017 Dec;15(12):1192-1198. doi: 10.1111/ddg.13380. Epub 2017 Nov 17.

PMID:
29148618
38.

Prognostic impact of atrial fibrillation in cardiogenic shock complicating acute myocardial infarction: a substudy of the IABP-SHOCK II trial.

de Waha S, Schoene K, Fuernau G, Desch S, Eitel I, Pöss J, Meyer-Saraei R, Eitel C, Tilz R, Schuler G, Werdan K, Schneider S, Ouarrak T, Zeymer U, Thiele H.

Clin Res Cardiol. 2018 Mar;107(3):233-240. doi: 10.1007/s00392-017-1175-1. Epub 2017 Nov 10.

PMID:
29127472
39.

Good Manufacturing Practice-Compliant Production and Lot-Release of Ex Vivo Expanded Regulatory T Cells As Basis for Treatment of Patients with Autoimmune and Inflammatory Disorders.

Wiesinger M, Stoica D, Roessner S, Lorenz C, Fischer A, Atreya R, Neufert CF, Atreya I, Scheffold A, Schuler-Thurner B, Neurath MF, Schuler G, Voskens CJ.

Front Immunol. 2017 Oct 26;8:1371. doi: 10.3389/fimmu.2017.01371. eCollection 2017.

40.

GM-CSF Monocyte-Derived Cells and Langerhans Cells As Part of the Dendritic Cell Family.

Lutz MB, Strobl H, Schuler G, Romani N.

Front Immunol. 2017 Oct 23;8:1388. doi: 10.3389/fimmu.2017.01388. eCollection 2017. Review.

41.

Efficiency of the sulfate pathway in comparison to the Δ4- and Δ5-pathway of steroidogenesis in the porcine testis.

Klymiuk MC, Neunzig J, Bernhardt R, Sánchez-Guijo A, Hartmann MF, Wudy SA, Schuler G.

J Steroid Biochem Mol Biol. 2018 May;179:64-72. doi: 10.1016/j.jsbmb.2017.10.017. Epub 2017 Nov 6.

PMID:
29107177
42.

Life-threatening Autoimmune Cardiomyopathy Reproducibly Induced in a Patient by Checkpoint Inhibitor Therapy.

Tajmir-Riahi A, Bergmann T, Schmid M, Agaimy A, Schuler G, Heinzerling L.

J Immunother. 2018 Jan;41(1):35-38. doi: 10.1097/CJI.0000000000000190.

PMID:
29077601
43.

Life-Threatening Atypical Case of Acute Generalized Exanthematous Pustulosis.

Tajmir-Riahi A, Wörl P, Harrer T, Schliep S, Schuler G, Simon M.

Int Arch Allergy Immunol. 2017;174(2):108-111. doi: 10.1159/000480700. Epub 2017 Oct 25.

PMID:
29065395
44.

Simultaneous profiles of sulfonated androgens, sulfonated estrogens and sulfonated progestogens in postpubertal boars (sus scrofa domestica) measured by LC-MS/MS.

Schuler G, Sánchez-Guijo A, Hartmann MF, Wudy SA.

J Steroid Biochem Mol Biol. 2018 May;179:55-63. doi: 10.1016/j.jsbmb.2017.10.006. Epub 2017 Oct 10.

PMID:
29030154
45.

Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein.

Buschow SI, Ramazzotti M, Reinieren-Beeren IMJ, Heinzerling LM, Westdorp H, Stefanini I, Beltrame L, Hato SV, Ellebaek E, Gross S, Nguyen VA, Weinlich G, Ragoussis J, Baban D, Schuler-Thurner B, Svane IM, Romani N, Austyn JM, De Vries IJM, Schuler G, Cavalieri D, Figdor CG.

Oncotarget. 2017 Jun 27;8(40):67439-67456. doi: 10.18632/oncotarget.18698. eCollection 2017 Sep 15.

46.

The art of measuring steroids: Principles and practice of current hormonal steroid analysis.

Wudy SA, Schuler G, Sánchez-Guijo A, Hartmann MF.

J Steroid Biochem Mol Biol. 2018 May;179:88-103. doi: 10.1016/j.jsbmb.2017.09.003. Epub 2017 Sep 28. Review.

PMID:
28962971
47.

Comparison of the Serum Tumor Markers S100 and Melanoma-inhibitory Activity (MIA) in the Monitoring of Patients with Metastatic Melanoma Receiving Vaccination Immunotherapy with Dendritic Cells.

Uslu U, Schliep S, Schliep K, Erdmann M, Koch HU, Parsch H, Rosenheinrich S, Anzengruber D, Bosserhoff AK, Schuler G, Schuler-Thurner B.

Anticancer Res. 2017 Sep;37(9):5033-5037.

PMID:
28870930
48.

Blood Pressure Response to Main Renal Artery and Combined Main Renal Artery Plus Branch Renal Denervation in Patients With Resistant Hypertension.

Fengler K, Ewen S, Höllriegel R, Rommel KP, Kulenthiran S, Lauder L, Cremers B, Schuler G, Linke A, Böhm M, Mahfoud F, Lurz P.

J Am Heart Assoc. 2017 Aug 10;6(8). pii: e006196. doi: 10.1161/JAHA.117.006196.

49.

RNA-transfection of γ/δ T cells with a chimeric antigen receptor or an α/β T-cell receptor: a safer alternative to genetically engineered α/β T cells for the immunotherapy of melanoma.

Harrer DC, Simon B, Fujii SI, Shimizu K, Uslu U, Schuler G, Gerer KF, Hoyer S, Dörrie J, Schaft N.

BMC Cancer. 2017 Aug 17;17(1):551. doi: 10.1186/s12885-017-3539-3.

50.

Response by von Roeder et al to Letter Regarding Article, "Influence of Left Atrial Function on Exercise Capacity and Left Ventricular Function in Patients With Heart Failure and Preserved Ejection Fraction".

von Roeder M, Rommel KP, Kowallick JT, Blazek S, Besler C, Fengler K, Lotz J, Hasenfuß G, Lücke C, Gutberlet M, Schuler G, Schuster A, Lurz P.

Circ Cardiovasc Imaging. 2017 Aug;10(8). pii: e006785. doi: 10.1161/CIRCIMAGING.117.006785. No abstract available.

PMID:
28790126

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