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Items: 7


Immunoproteasome deficiency protects in the retina after optic nerve crush.

Schuld NJ, Hussong SA, Kapphahn RJ, Lehmann U, Roehrich H, Rageh AA, Heuss ND, Bratten W, Gregerson DS, Ferrington DA.

PLoS One. 2015 May 15;10(5):e0126768. doi: 10.1371/journal.pone.0126768. eCollection 2015.


SmgGDS-558 regulates the cell cycle in pancreatic, non-small cell lung, and breast cancers.

Schuld NJ, Hauser AD, Gastonguay AJ, Wilson JM, Lorimer EL, Williams CL.

Cell Cycle. 2014;13(6):941-52. doi: 10.4161/cc.27804. Epub 2014 Jan 16.


The chaperone protein SmgGDS interacts with small GTPases entering the prenylation pathway by recognizing the last amino acid in the CAAX motif.

Schuld NJ, Vervacke JS, Lorimer EL, Simon NC, Hauser AD, Barbieri JT, Distefano MD, Williams CL.

J Biol Chem. 2014 Mar 7;289(10):6862-76. doi: 10.1074/jbc.M113.527192. Epub 2014 Jan 10.


The SmgGDS splice variant SmgGDS-558 is a key promoter of tumor growth and RhoA signaling in breast cancer.

Hauser AD, Bergom C, Schuld NJ, Chen X, Lorimer EL, Huang J, Mackinnon AC, Williams CL.

Mol Cancer Res. 2014 Jan;12(1):130-42. doi: 10.1158/1541-7786.MCR-13-0362. Epub 2013 Nov 6.


An adenosine-mediated signaling pathway suppresses prenylation of the GTPase Rap1B and promotes cell scattering.

Ntantie E, Gonyo P, Lorimer EL, Hauser AD, Schuld N, McAllister D, Kalyanaraman B, Dwinell MB, Auchampach JA, Williams CL.

Sci Signal. 2013 May 28;6(277):ra39. doi: 10.1126/scisignal.2003374.


The role of Rac1 in the regulation of NF-κB activity, cell proliferation, and cell migration in non-small cell lung carcinoma.

Gastonguay A, Berg T, Hauser AD, Schuld N, Lorimer E, Williams CL.

Cancer Biol Ther. 2012 Jun;13(8):647-56. doi: 10.4161/cbt.20082. Epub 2012 Jun 1.


Quantitative real-time polymerase chain reaction (qRT-PCR) restriction fragment length polymorphism (RFLP) method for monitoring highly conserved transgene expression during gene therapy.

Bruzzone CM, Belcher JD, Schuld NJ, Newman KA, Vineyard J, Nguyen J, Chen C, Beckman JD, Steer CJ, Vercellotti GM.

Transl Res. 2008 Dec;152(6):290-7. doi: 10.1016/j.trsl.2008.10.005. Epub 2008 Nov 4.

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