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Items: 36

1.

The effect of P38 MAP kinase inhibition in a mouse model of influenza.

Growcott EJ, Bamba D, Galarneau JR, Leonard VHJ, Schul W, Stein D, Osborne CS.

J Med Microbiol. 2018 Mar;67(3):452-462. doi: 10.1099/jmm.0.000684. Epub 2018 Jan 24.

PMID:
29458547
2.

Activation of peripheral blood mononuclear cells by dengue virus infection depotentiates balapiravir.

Chen YL, Abdul Ghafar N, Karuna R, Fu Y, Lim SP, Schul W, Gu F, Herve M, Yokohama F, Wang G, Cerny D, Fink K, Blasco F, Shi PY.

J Virol. 2014 Feb;88(3):1740-7. doi: 10.1128/JVI.02841-13. Epub 2013 Nov 20.

3.

Testing antiviral compounds in a dengue mouse model.

Schul W, Yip A, Shi PY.

Methods Mol Biol. 2013;1030:269-81. doi: 10.1007/978-1-62703-484-5_21.

PMID:
23821275
4.

The structural basis for serotype-specific neutralization of dengue virus by a human antibody.

Teoh EP, Kukkaro P, Teo EW, Lim AP, Tan TT, Yip A, Schul W, Aung M, Kostyuchenko VA, Leo YS, Chan SH, Smith KG, Chan AH, Zou G, Ooi EE, Kemeny DM, Tan GK, Ng JK, Ng ML, Alonso S, Fisher D, Shi PY, Hanson BJ, Lok SM, MacAry PA.

Sci Transl Med. 2012 Jun 20;4(139):139ra83. doi: 10.1126/scitranslmed.3003888.

5.

Competitive inhibitor of cellular α-glucosidases protects mice from lethal dengue virus infection.

Chang J, Schul W, Yip A, Xu X, Guo JT, Block TM.

Antiviral Res. 2011 Nov;92(2):369-71. doi: 10.1016/j.antiviral.2011.08.003. Epub 2011 Aug 11.

6.

A translation inhibitor that suppresses dengue virus in vitro and in vivo.

Wang QY, Kondreddi RR, Xie X, Rao R, Nilar S, Xu HY, Qing M, Chang D, Dong H, Yokokawa F, Lakshminarayana SB, Goh A, Schul W, Kramer L, Keller TH, Shi PY.

Antimicrob Agents Chemother. 2011 Sep;55(9):4072-80. doi: 10.1128/AAC.00620-11. Epub 2011 Jul 5.

7.

A single amino acid in nonstructural protein NS4B confers virulence to dengue virus in AG129 mice through enhancement of viral RNA synthesis.

Grant D, Tan GK, Qing M, Ng JK, Yip A, Zou G, Xie X, Yuan Z, Schreiber MJ, Schul W, Shi PY, Alonso S.

J Virol. 2011 Aug;85(15):7775-87. doi: 10.1128/JVI.00665-11. Epub 2011 Jun 1.

8.

Inhibition of dengue virus through suppression of host pyrimidine biosynthesis.

Wang QY, Bushell S, Qing M, Xu HY, Bonavia A, Nunes S, Zhou J, Poh MK, Florez de Sessions P, Niyomrattanakit P, Dong H, Hoffmaster K, Goh A, Nilar S, Schul W, Jones S, Kramer L, Compton T, Shi PY.

J Virol. 2011 Jul;85(13):6548-56. doi: 10.1128/JVI.02510-10. Epub 2011 Apr 20.

9.

Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo.

Chang J, Schul W, Butters TD, Yip A, Liu B, Goh A, Lakshminarayana SB, Alonzi D, Reinkensmeier G, Pan X, Qu X, Weidner JM, Wang L, Yu W, Borune N, Kinch MA, Rayahin JE, Moriarty R, Xu X, Shi PY, Guo JT, Block TM.

Antiviral Res. 2011 Jan;89(1):26-34. doi: 10.1016/j.antiviral.2010.11.002. Epub 2010 Nov 10.

10.

Inhibition of dengue virus by an ester prodrug of an adenosine analog.

Chen YL, Yin Z, Lakshminarayana SB, Qing M, Schul W, Duraiswamy J, Kondreddi RR, Goh A, Xu HY, Yip A, Liu B, Weaver M, Dartois V, Keller TH, Shi PY.

Antimicrob Agents Chemother. 2010 Aug;54(8):3255-61. doi: 10.1128/AAC.00397-10. Epub 2010 Jun 1.

11.

Inhibition of dengue virus RNA synthesis by an adenosine nucleoside.

Chen YL, Yin Z, Duraiswamy J, Schul W, Lim CC, Liu B, Xu HY, Qing M, Yip A, Wang G, Chan WL, Tan HP, Lo M, Liung S, Kondreddi RR, Rao R, Gu H, He H, Keller TH, Shi PY.

Antimicrob Agents Chemother. 2010 Jul;54(7):2932-9. doi: 10.1128/AAC.00140-10. Epub 2010 May 10.

12.

A non mouse-adapted dengue virus strain as a new model of severe dengue infection in AG129 mice.

Tan GK, Ng JK, Trasti SL, Schul W, Yip G, Alonso S.

PLoS Negl Trop Dis. 2010 Apr 27;4(4):e672. doi: 10.1371/journal.pntd.0000672. Erratum in: PLoS Negl Trop Dis. 2010;4(10). doi: 10.1371/annotation/03774b36-c453-404a-b295-7b91bfd9cebd.

13.

Strategies for development of Dengue virus inhibitors.

Noble CG, Chen YL, Dong H, Gu F, Lim SP, Schul W, Wang QY, Shi PY.

Antiviral Res. 2010 Mar;85(3):450-62. doi: 10.1016/j.antiviral.2009.12.011. Epub 2010 Jan 8. Review.

PMID:
20060421
14.

An adenosine nucleoside inhibitor of dengue virus.

Yin Z, Chen YL, Schul W, Wang QY, Gu F, Duraiswamy J, Kondreddi RR, Niyomrattanakit P, Lakshminarayana SB, Goh A, Xu HY, Liu W, Liu B, Lim JY, Ng CY, Qing M, Lim CC, Yip A, Wang G, Chan WL, Tan HP, Lin K, Zhang B, Zou G, Bernard KA, Garrett C, Beltz K, Dong M, Weaver M, He H, Pichota A, Dartois V, Keller TH, Shi PY.

Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20435-9. doi: 10.1073/pnas.0907010106. Epub 2009 Nov 16.

15.

A small molecule fusion inhibitor of dengue virus.

Poh MK, Yip A, Zhang S, Priestle JP, Ma NL, Smit JM, Wilschut J, Shi PY, Wenk MR, Schul W.

Antiviral Res. 2009 Dec;84(3):260-6. doi: 10.1016/j.antiviral.2009.09.011. Epub 2009 Oct 1.

PMID:
19800368
16.

Depletion of macrophages in mice results in higher dengue virus titers and highlights the role of macrophages for virus control.

Fink K, Ng C, Nkenfou C, Vasudevan SG, van Rooijen N, Schul W.

Eur J Immunol. 2009 Oct;39(10):2809-21. doi: 10.1002/eji.200939389.

17.

On a mouse monoclonal antibody that neutralizes all four dengue virus serotypes.

Rajamanonmani R, Nkenfou C, Clancy P, Yau YH, Shochat SG, Sukupolvi-Petty S, Schul W, Diamond MS, Vasudevan SG, Lescar J.

J Gen Virol. 2009 Apr;90(Pt 4):799-809. doi: 10.1099/vir.0.006874-0. Epub 2009 Mar 4.

18.

A small-molecule dengue virus entry inhibitor.

Wang QY, Patel SJ, Vangrevelinghe E, Xu HY, Rao R, Jaber D, Schul W, Gu F, Heudi O, Ma NL, Poh MK, Phong WY, Keller TH, Jacoby E, Vasudevan SG.

Antimicrob Agents Chemother. 2009 May;53(5):1823-31. doi: 10.1128/AAC.01148-08. Epub 2009 Feb 17.

19.

A dengue fever viremia model in mice shows reduction in viral replication and suppression of the inflammatory response after treatment with antiviral drugs.

Schul W, Liu W, Xu HY, Flamand M, Vasudevan SG.

J Infect Dis. 2007 Mar 1;195(5):665-74. Epub 2007 Jan 23.

PMID:
17262707
20.

Differential role of basal keratinocytes in UV-induced immunosuppression and skin cancer.

Jans J, Garinis GA, Schul W, van Oudenaren A, Moorhouse M, Smid M, Sert YG, van der Velde A, Rijksen Y, de Gruijl FR, van der Spek PJ, Yasui A, Hoeijmakers JH, Leenen PJ, van der Horst GT.

Mol Cell Biol. 2006 Nov;26(22):8515-26. Epub 2006 Sep 11.

21.

Powerful skin cancer protection by a CPD-photolyase transgene.

Jans J, Schul W, Sert YG, Rijksen Y, Rebel H, Eker AP, Nakajima S, van Steeg H, de Gruijl FR, Yasui A, Hoeijmakers JH, van der Horst GT.

Curr Biol. 2005 Jan 26;15(2):105-15.

22.

Enhanced repair of cyclobutane pyrimidine dimers and improved UV resistance in photolyase transgenic mice.

Schul W, Jans J, Rijksen YM, Klemann KH, Eker AP, de Wit J, Nikaido O, Nakajima S, Yasui A, Hoeijmakers JH, van der Horst GT.

EMBO J. 2002 Sep 2;21(17):4719-29.

23.

Sequential assembly of the nucleotide excision repair factors in vivo.

Volker M, Moné MJ, Karmakar P, van Hoffen A, Schul W, Vermeulen W, Hoeijmakers JH, van Driel R, van Zeeland AA, Mullenders LH.

Mol Cell. 2001 Jul;8(1):213-24.

24.

Nuclear domains enriched in RNA 3'-processing factors associate with coiled bodies and histone genes in a cell cycle-dependent manner.

Schul W, van Der Kraan I, Matera AG, van Driel R, de Jong L.

Mol Biol Cell. 1999 Nov;10(11):3815-24.

25.

Coiled bodies are predisposed to a spatial association with genes that contain snoRNA sequences in their introns.

Schul W, Adelaar B, van Driel R, de Jong L.

J Cell Biochem. 1999 Dec 1;75(3):393-403.

PMID:
10536363
26.
27.

Nuclear neighbours: the spatial and functional organization of genes and nuclear domains.

Schul W, de Jong L, van Driel R.

J Cell Biochem. 1998 Aug 1;70(2):159-71. Review.

PMID:
9671222
28.
31.

RING1 is associated with the polycomb group protein complex and acts as a transcriptional repressor.

Satijn DP, Gunster MJ, van der Vlag J, Hamer KM, Schul W, Alkema MJ, Saurin AJ, Freemont PS, van Driel R, Otte AP.

Mol Cell Biol. 1997 Jul;17(7):4105-13.

32.

PML-containing nuclear bodies: their spatial distribution in relation to other nuclear components.

Grande MA, van der Kraan I, van Steensel B, Schul W, de Thé H, van der Voort HT, de Jong L, van Driel R.

J Cell Biochem. 1996 Dec 1;63(3):280-91.

PMID:
8913879
33.

The RNA 3' cleavage factors CstF 64 kDa and CPSF 100 kDa are concentrated in nuclear domains closely associated with coiled bodies and newly synthesized RNA.

Schul W, Groenhout B, Koberna K, Takagaki Y, Jenny A, Manders EM, Raska I, van Driel R, de Jong L.

EMBO J. 1996 Jun 3;15(11):2883-92.

34.

Nuclear domains involved in RNA synthesis, RNA processing, and replication.

de Jong L, Grande MA, Mattern KA, Schul W, van Driel R.

Crit Rev Eukaryot Gene Expr. 1996;6(2-3):215-46. Review.

PMID:
8855389
35.

Nuclear domains and the nuclear matrix.

van Driel R, Wansink DG, van Steensel B, Grande MA, Schul W, de Jong L.

Int Rev Cytol. 1995;162A:151-89. Review.

PMID:
8575880
36.

Fluorescent labeling of nascent RNA reveals transcription by RNA polymerase II in domains scattered throughout the nucleus.

Wansink DG, Schul W, van der Kraan I, van Steensel B, van Driel R, de Jong L.

J Cell Biol. 1993 Jul;122(2):283-93.

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