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Items: 1 to 50 of 193

1.

COX6A2 variants cause a muscle-specific cytochrome c oxidase deficiency.

Inoue M, Uchino S, Iida A, Noguchi S, Hayashi S, Takahashi T, Fujii K, Komaki H, Takeshita E, Nonaka I, Okada Y, Yoshizawa T, Van Lommel L, Schuit F, Goto YI, Mimaki M, Nishino I.

Ann Neurol. 2019 Jun 2. doi: 10.1002/ana.25517. [Epub ahead of print]

PMID:
31155743
2.

Functional peroxisomes are required for β-cell integrity in mice.

Baboota RK, Shinde AB, Lemaire K, Fransen M, Vinckier S, Van Veldhoven PP, Schuit F, Baes M.

Mol Metab. 2019 Apr;22:71-83. doi: 10.1016/j.molmet.2019.02.001. Epub 2019 Feb 8.

3.

Gene and Mirna Regulatory Networks During Different Stages of Crohn's Disease.

Verstockt S, De Hertogh G, Van der Goten J, Verstockt B, Vancamelbeke M, Machiels K, Van Lommel L, Schuit F, Van Assche G, Rutgeerts P, Ferrante M, Vermeire S, Arijs I, Cleynen I.

J Crohns Colitis. 2019 Jan 18. doi: 10.1093/ecco-jcc/jjz007. [Epub ahead of print]

PMID:
30657881
4.

Natural killer cell infiltration is discriminative for antibody-mediated rejection and predicts outcome after kidney transplantation.

Yazdani S, Callemeyn J, Gazut S, Lerut E, de Loor H, Wevers M, Heylen L, Saison C, Koenig A, Thaunat O, Thorrez L, Kuypers D, Sprangers B, Noël LH, Van Lommel L, Schuit F, Essig M, Gwinner W, Anglicheau D, Marquet P, Naesens M.

Kidney Int. 2019 Jan;95(1):188-198. doi: 10.1016/j.kint.2018.08.027. Epub 2018 Nov 3.

5.

Adrenal hormones mediate disease tolerance in malaria.

Vandermosten L, Pham TT, Knoops S, De Geest C, Lays N, Van der Molen K, Kenyon CJ, Verma M, Chapman KE, Schuit F, De Bosscher K, Opdenakker G, Van den Steen PE.

Nat Commun. 2018 Oct 30;9(1):4525. doi: 10.1038/s41467-018-06986-5.

6.

Transgenic Artifacts Caused by Passenger Human Growth Hormone.

de Faudeur G, Brouwers B, Schuit F, Creemers JWM, Ramos-Molina B.

Trends Endocrinol Metab. 2018 Oct;29(10):670-674. doi: 10.1016/j.tem.2018.05.005. Epub 2018 Jun 18. Review.

PMID:
29921469
7.

Genetic and Transcriptomic Bases of Intestinal Epithelial Barrier Dysfunction in Inflammatory Bowel Disease.

Vancamelbeke M, Vanuytsel T, Farré R, Verstockt S, Ferrante M, Van Assche G, Rutgeerts P, Schuit F, Vermeire S, Arijs I, Cleynen I.

Inflamm Bowel Dis. 2017 Oct;23(10):1718-1729. doi: 10.1097/MIB.0000000000001246.

8.

How stable is repression of disallowed genes in pancreatic islets in response to metabolic stress?

Lemaire K, Granvik M, Schraenen A, Goyvaerts L, Van Lommel L, Gómez-Ruiz A, In 't Veld P, Gilon P, Schuit F.

PLoS One. 2017 Aug 9;12(8):e0181651. doi: 10.1371/journal.pone.0181651. eCollection 2017.

9.

Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity.

Philippaert K, Pironet A, Mesuere M, Sones W, Vermeiren L, Kerselaers S, Pinto S, Segal A, Antoine N, Gysemans C, Laureys J, Lemaire K, Gilon P, Cuypers E, Tytgat J, Mathieu C, Schuit F, Rorsman P, Talavera K, Voets T, Vennekens R.

Nat Commun. 2017 Mar 31;8:14733. doi: 10.1038/ncomms14733.

10.

Early differences in islets from prediabetic NOD mice: combined microarray and proteomic analysis.

Crèvecoeur I, Gudmundsdottir V, Vig S, Marques Câmara Sodré F, D'Hertog W, Fierro AC, Van Lommel L, Gysemans C, Marchal K, Waelkens E, Schuit F, Brunak S, Overbergh L, Mathieu C.

Diabetologia. 2017 Mar;60(3):475-489. doi: 10.1007/s00125-016-4191-1. Epub 2017 Jan 12.

PMID:
28078386
11.

Effect of vedolizumab (anti-α4β7-integrin) therapy on histological healing and mucosal gene expression in patients with UC.

Arijs I, De Hertogh G, Lemmens B, Van Lommel L, de Bruyn M, Vanhove W, Cleynen I, Machiels K, Ferrante M, Schuit F, Van Assche G, Rutgeerts P, Vermeire S.

Gut. 2018 Jan;67(1):43-52. doi: 10.1136/gutjnl-2016-312293. Epub 2016 Oct 7.

PMID:
27802155
12.

Genetic Deletion of Tissue Inhibitor of Metalloproteinase-1/TIMP-1 Alters Inflammation and Attenuates Fibrosis in Dextran Sodium Sulphate-induced Murine Models of Colitis.

Breynaert C, de Bruyn M, Arijs I, Cremer J, Martens E, Van Lommel L, Geboes K, De Hertogh G, Schuit F, Ferrante M, Vermeire S, Ceuppens J, Opdenakker G, Van Assche G.

J Crohns Colitis. 2016 Nov;10(11):1336-1350. Epub 2016 May 17.

PMID:
27194531
13.

Disallowed and Allowed Gene Expression: Two Faces of Mature Islet Beta Cells.

Lemaire K, Thorrez L, Schuit F.

Annu Rev Nutr. 2016 Jul 17;36:45-71. doi: 10.1146/annurev-nutr-071715-050808. Epub 2016 May 4. Review.

PMID:
27146011
14.

Serotonin competence of mouse beta cells during pregnancy.

Goyvaerts L, Schraenen A, Schuit F.

Diabetologia. 2016 Jul;59(7):1356-1363. doi: 10.1007/s00125-016-3951-2. Epub 2016 Apr 7. Review.

PMID:
27056372
15.

Effect of a transcriptional inactive or absent vitamin D receptor on beta-cell function and glucose homeostasis in mice.

Vangoitsenhoven R, Wolden-Kirk H, Lemaire K, Verstuyf A, Verlinden L, Yamamoto Y, Kato S, Van Lommel L, Schuit F, Van der Schueren B, Mathieu C, Overbergh L.

J Steroid Biochem Mol Biol. 2016 Nov;164:309-317. doi: 10.1016/j.jsbmb.2016.02.011. Epub 2016 Feb 11.

PMID:
26877201
16.

Endoplasmic reticulum-associated degradation of the mouse PC1/3-N222D hypomorph and human PCSK1 mutations contributes to obesity.

Stijnen P, Brouwers B, Dirkx E, Ramos-Molina B, Van Lommel L, Schuit F, Thorrez L, Declercq J, Creemers JW.

Int J Obes (Lond). 2016 Jun;40(6):973-81. doi: 10.1038/ijo.2016.3. Epub 2016 Jan 20.

PMID:
26786350
17.

Longitudinal three-dimensional visualisation of autoimmune diabetes by functional optical coherence imaging.

Berclaz C, Schmidt-Christensen A, Szlag D, Extermann J, Hansen L, Bouwens A, Villiger M, Goulley J, Schuit F, Grapin-Botton A, Lasser T, Holmberg D.

Diabetologia. 2016 Mar;59(3):550-9. doi: 10.1007/s00125-015-3819-x. Epub 2015 Nov 27.

PMID:
26613896
18.

Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease.

Vanhove W, Peeters PM, Staelens D, Schraenen A, Van der Goten J, Cleynen I, De Schepper S, Van Lommel L, Reynaert NL, Schuit F, Van Assche G, Ferrante M, De Hertogh G, Wouters EF, Rutgeerts P, Vermeire S, Nys K, Arijs I.

Inflamm Bowel Dis. 2015 Nov;21(11):2673-82. doi: 10.1097/MIB.0000000000000535.

PMID:
26313692
19.

Metabolic and Behavioural Phenotypes in Nestin-Cre Mice Are Caused by Hypothalamic Expression of Human Growth Hormone.

Declercq J, Brouwers B, Pruniau VP, Stijnen P, de Faudeur G, Tuand K, Meulemans S, Serneels L, Schraenen A, Schuit F, Creemers JW.

PLoS One. 2015 Aug 14;10(8):e0135502. doi: 10.1371/journal.pone.0135502. eCollection 2015.

20.

Epigenetic programming of glucose-regulated insulin release.

Schuit F.

J Clin Invest. 2015 Jul 1;125(7):2565-8. doi: 10.1172/JCI82575. Epub 2015 Jun 22.

21.

Comparative genomics: beyond the horizon of the next research grant.

Schuit F.

Diabetologia. 2015 Aug;58(8):1720-4. doi: 10.1007/s00125-015-3620-x. Epub 2015 May 14.

PMID:
25968988
22.

Prolactin receptors and placental lactogen drive male mouse pancreatic islets to pregnancy-related mRNA changes.

Goyvaerts L, Lemaire K, Arijs I, Auffret J, Granvik M, Van Lommel L, Binart N, in't Veld P, Schuit F, Schraenen A.

PLoS One. 2015 Mar 27;10(3):e0121868. doi: 10.1371/journal.pone.0121868. eCollection 2015.

23.

Vitamin D3 Induces Tolerance in Human Dendritic Cells by Activation of Intracellular Metabolic Pathways.

Ferreira GB, Vanherwegen AS, Eelen G, Gutiérrez ACF, Van Lommel L, Marchal K, Verlinden L, Verstuyf A, Nogueira T, Georgiadou M, Schuit F, Eizirik DL, Gysemans C, Carmeliet P, Overbergh L, Mathieu C.

Cell Rep. 2015 Feb 10;10(5):711-725. doi: 10.1016/j.celrep.2015.01.013. Epub 2015 Feb 7.

24.

Integrated miRNA and mRNA expression profiling in inflamed colon of patients with ulcerative colitis.

Van der Goten J, Vanhove W, Lemaire K, Van Lommel L, Machiels K, Wollants WJ, De Preter V, De Hertogh G, Ferrante M, Van Assche G, Rutgeerts P, Schuit F, Vermeire S, Arijs I.

PLoS One. 2014 Dec 29;9(12):e116117. doi: 10.1371/journal.pone.0116117. eCollection 2014.

25.

Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression.

Brouwers B, de Faudeur G, Osipovich AB, Goyvaerts L, Lemaire K, Boesmans L, Cauwelier EJ, Granvik M, Pruniau VP, Van Lommel L, Van Schoors J, Stancill JS, Smolders I, Goffin V, Binart N, in't Veld P, Declercq J, Magnuson MA, Creemers JW, Schuit F, Schraenen A.

Cell Metab. 2014 Dec 2;20(6):979-90. doi: 10.1016/j.cmet.2014.11.004.

26.

A complex Xp11.22 deletion in a patient with syndromic autism: exploration of FAM120C as a positional candidate gene for autism.

De Wolf V, Crepel A, Schuit F, van Lommel L, Ceulemans B, Steyaert J, Seuntjens E, Peeters H, Devriendt K.

Am J Med Genet A. 2014 Dec;164A(12):3035-41. doi: 10.1002/ajmg.a.36752. Epub 2014 Sep 24.

PMID:
25258334
27.

Inflammation-Induced Downregulation of Butyrate Uptake and Oxidation Is Not Caused by a Reduced Gene Expression.

Boesmans L, Ramakers M, Arijs I, Windey K, Vanhove W, Schuit F, Rutgeerts P, Verbeke K, De Preter V.

J Cell Physiol. 2015 Feb;230(2):418-26. doi: 10.1002/jcp.24725.

PMID:
25059646
28.

Discovery of molecular pathways mediating 1,25-dihydroxyvitamin D3 protection against cytokine-induced inflammation and damage of human and male mouse islets of Langerhans.

Wolden-Kirk H, Rondas D, Bugliani M, Korf H, Van Lommel L, Brusgaard K, Christesen HT, Schuit F, Proost P, Masini M, Marchetti P, Eizirik DL, Overbergh L, Mathieu C.

Endocrinology. 2014 Mar;155(3):736-47. doi: 10.1210/en.2013-1409. Epub 2014 Jan 1.

PMID:
24424042
29.

Infliximab restores the dysfunctional matrix remodeling protein and growth factor gene expression in patients with inflammatory bowel disease.

de Bruyn M, Machiels K, Vandooren J, Lemmens B, Van Lommel L, Breynaert C, Van der Goten J, Staelens D, Billiet T, De Hertogh G, Ferrante M, Van Assche G, Vermeire S, Opdenakker G, Schuit F, Rutgeerts P, Arijs I.

Inflamm Bowel Dis. 2014 Feb;20(2):339-52. doi: 10.1097/01.MIB.0000438430.15553.90.

PMID:
24378596
30.

Gene expression profiling of early hepatic stellate cell activation reveals a role for Igfbp3 in cell migration.

Mannaerts I, Schroyen B, Verhulst S, Van Lommel L, Schuit F, Nyssen M, van Grunsven LA.

PLoS One. 2013 Dec 17;8(12):e84071. doi: 10.1371/journal.pone.0084071. eCollection 2013.

31.

Insulin downregulates the expression of the Ca2+-activated nonselective cation channel TRPM5 in pancreatic islets from leptin-deficient mouse models.

Colsoul B, Jacobs G, Philippaert K, Owsianik G, Segal A, Nilius B, Voets T, Schuit F, Vennekens R.

Pflugers Arch. 2014 Mar;466(3):611-21. doi: 10.1007/s00424-013-1389-7. Epub 2013 Nov 13.

32.

Glucose-stimulated insulin secretion: the hierarchy of its multiple cellular and subcellular mechanisms.

Meda P, Schuit F.

Diabetologia. 2013 Dec;56(12):2552-5. doi: 10.1007/s00125-013-3073-z. Epub 2013 Oct 11.

PMID:
24114115
33.

Phlorizin pretreatment reduces acute renal toxicity in a mouse model for diabetic nephropathy.

Brouwers B, Pruniau VP, Cauwelier EJ, Schuit F, Lerut E, Ectors N, Declercq J, Creemers JW.

J Biol Chem. 2013 Sep 20;288(38):27200-7. doi: 10.1074/jbc.M113.469486. Epub 2013 Aug 11.

34.

Role of PFKFB3-driven glycolysis in vessel sprouting.

De Bock K, Georgiadou M, Schoors S, Kuchnio A, Wong BW, Cantelmo AR, Quaegebeur A, Ghesquière B, Cauwenberghs S, Eelen G, Phng LK, Betz I, Tembuyser B, Brepoels K, Welti J, Geudens I, Segura I, Cruys B, Bifari F, Decimo I, Blanco R, Wyns S, Vangindertael J, Rocha S, Collins RT, Munck S, Daelemans D, Imamura H, Devlieger R, Rider M, Van Veldhoven PP, Schuit F, Bartrons R, Hofkens J, Fraisl P, Telang S, Deberardinis RJ, Schoonjans L, Vinckier S, Chesney J, Gerhardt H, Dewerchin M, Carmeliet P.

Cell. 2013 Aug 1;154(3):651-63. doi: 10.1016/j.cell.2013.06.037.

35.

Unique gene expression and MR T2 relaxometry patterns define chronic murine dextran sodium sulphate colitis as a model for connective tissue changes in human Crohn's disease.

Breynaert C, Dresselaers T, Perrier C, Arijs I, Cremer J, Van Lommel L, Van Steen K, Ferrante M, Schuit F, Vermeire S, Rutgeerts P, Himmelreich U, Ceuppens JL, Geboes K, Van Assche G.

PLoS One. 2013 Jul 23;8(7):e68876. doi: 10.1371/journal.pone.0068876. Print 2013.

36.

Characterization of proposed human B-1 cells reveals pre-plasmablast phenotype.

Covens K, Verbinnen B, Geukens N, Meyts I, Schuit F, Van Lommel L, Jacquemin M, Bossuyt X.

Blood. 2013 Jun 27;121(26):5176-83. doi: 10.1182/blood-2012-12-471953. Epub 2013 Apr 23.

37.

Potential of protein phosphatase inhibitor 1 as biomarker of pancreatic β-cell injury in vitro and in vivo.

Jiang L, Brackeva B, Ling Z, Kramer G, Aerts JM, Schuit F, Keymeulen B, Pipeleers D, Gorus F, Martens GA.

Diabetes. 2013 Aug;62(8):2683-8. doi: 10.2337/db12-1507. Epub 2013 Apr 4.

38.

Mice deficient in the respiratory chain gene Cox6a2 are protected against high-fat diet-induced obesity and insulin resistance.

Quintens R, Singh S, Lemaire K, De Bock K, Granvik M, Schraenen A, Vroegrijk IO, Costa V, Van Noten P, Lambrechts D, Lehnert S, Van Lommel L, Thorrez L, De Faudeur G, Romijn JA, Shelton JM, Scorrano L, Lijnen HR, Voshol PJ, Carmeliet P, Mammen PP, Schuit F.

PLoS One. 2013;8(2):e56719. doi: 10.1371/journal.pone.0056719. Epub 2013 Feb 27.

39.

Decreased mucosal sulfide detoxification capacity in patients with Crohn's disease.

Arijs I, Vanhove W, Rutgeerts P, Schuit F, Verbeke K, De Preter V.

Inflamm Bowel Dis. 2013 Apr;19(5):E70-2. doi: 10.1097/MIB.0b013e31827e790e. No abstract available.

PMID:
23399736
40.

Tolbutamide controls glucagon release from mouse islets differently than glucose: involvement of K(ATP) channels from both α-cells and δ-cells.

Cheng-Xue R, Gómez-Ruiz A, Antoine N, Noël LA, Chae HY, Ravier MA, Chimienti F, Schuit FC, Gilon P.

Diabetes. 2013 May;62(5):1612-22. doi: 10.2337/db12-0347. Epub 2013 Feb 4.

41.

Modulation of protein fermentation does not affect fecal water toxicity: a randomized cross-over study in healthy subjects.

Windey K, De Preter V, Louat T, Schuit F, Herman J, Vansant G, Verbeke K.

PLoS One. 2012;7(12):e52387. doi: 10.1371/journal.pone.0052387. Epub 2012 Dec 20.

42.

Unraveling the effects of 1,25OH2D3 on global gene expression in pancreatic islets.

Wolden-Kirk H, Overbergh L, Gysemans C, Brusgaard K, Naamane N, Van Lommel L, Schuit F, Eizirik DL, Christesen H, Mathieu C.

J Steroid Biochem Mol Biol. 2013 Jul;136:68-79. doi: 10.1016/j.jsbmb.2012.10.017. Epub 2012 Nov 5.

PMID:
23137852
43.

Interleukin-15 receptor α expression in inflammatory bowel disease patients before and after normalization of inflammation with infliximab.

Perrier C, Arijs I, Staelens D, Breynaert C, Cleynen I, Covens K, Ferrante M, Van Assche G, Vermeire S, de Hertogh G, Schuit F, Rutgeerts P, Ceuppens JL.

Immunology. 2013 Jan;138(1):47-56. doi: 10.1111/imm.12014.

44.

Integrating insulin secretion and ER stress in pancreatic β-cells.

Lemaire K, Schuit F.

Nat Cell Biol. 2012 Oct;14(10):979-81. doi: 10.1038/ncb2594.

PMID:
23033046
45.

Endometrial gene expression in the early luteal phase is impacted by mode of triggering final oocyte maturation in recFSH stimulated and GnRH antagonist co-treated IVF cycles.

Humaidan P, Van Vaerenbergh I, Bourgain C, Alsbjerg B, Blockeel C, Schuit F, Van Lommel L, Devroey P, Fatemi H.

Hum Reprod. 2012 Nov;27(11):3259-72. doi: 10.1093/humrep/des279. Epub 2012 Aug 28.

PMID:
22930004
46.

A role for selective androgen response elements in the development of the epididymis and the androgen control of the 5α reductase II gene.

Kerkhofs S, Dubois V, De Gendt K, Helsen C, Clinckemalie L, Spans L, Schuit F, Boonen S, Vanderschueren D, Saunders PT, Verhoeven G, Claessens F.

FASEB J. 2012 Oct;26(10):4360-72. doi: 10.1096/fj.11-202283. Epub 2012 Jul 13.

PMID:
22798427
47.

Zinc transporters and their role in the pancreatic β-cell.

Lemaire K, Chimienti F, Schuit F.

J Diabetes Investig. 2012 Jun 6;3(3):202-11. doi: 10.1111/j.2040-1124.2012.00199.x. Review.

48.

β-cell-specific gene repression: a mechanism to protect against inappropriate or maladjusted insulin secretion?

Schuit F, Van Lommel L, Granvik M, Goyvaerts L, de Faudeur G, Schraenen A, Lemaire K.

Diabetes. 2012 May;61(5):969-75. doi: 10.2337/db11-1564. No abstract available.

49.

Impaired expression of genes involved in the butyrate oxidation pathway in Crohn's disease patients.

De Preter V, Rutgeerts P, Schuit F, Verbeke K, Arijs I.

Inflamm Bowel Dis. 2013 Mar;19(3):E43-4. doi: 10.1002/ibd.22970. No abstract available.

PMID:
22508661
50.

Decreased mucosal sulfide detoxification is related to an impaired butyrate oxidation in ulcerative colitis.

De Preter V, Arijs I, Windey K, Vanhove W, Vermeire S, Schuit F, Rutgeerts P, Verbeke K.

Inflamm Bowel Dis. 2012 Dec;18(12):2371-80. doi: 10.1002/ibd.22949. Epub 2012 Mar 20.

PMID:
22434643

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