Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 121

1.

Antiviral potential of human IFN-α subtypes against influenza A H3N2 infection in human lung explants reveals subtype-specific activities.

Matos ADR, Wunderlich K, Schloer S, Schughart K, Geffers R, Seders M, Witt M, Christersson A, Wiewrodt R, Wiebe K, Barth P, Hocke A, Hippenstiel S, Hönzke K, Dittmer U, Sutter K, Rescher U, Rodionycheva S, Matera N, Ludwig S, Brunotte L.

Emerg Microbes Infect. 2019;8(1):1763-1776. doi: 10.1080/22221751.2019.1698271.

PMID:
31826721
2.

Multiplex profiling of inflammation-related bioactive lipid mediators in Toxocara canis- and Toxocara cati-induced neurotoxocarosis.

Waindok P, Janecek-Erfurth E, Lindenwald D, Wilk E, Schughart K, Geffers R, Balas L, Durand T, Rund KM, Schebb NH, Strube C.

PLoS Negl Trop Dis. 2019 Sep 26;13(9):e0007706. doi: 10.1371/journal.pntd.0007706. eCollection 2019 Sep.

3.

Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection.

Tang BM, Shojaei M, Teoh S, Meyers A, Ho J, Ball TB, Keynan Y, Pisipati A, Kumar A, Eisen DP, Lai K, Gillett M, Santram R, Geffers R, Schreiber J, Mozhui K, Huang S, Parnell GP, Nalos M, Holubova M, Chew T, Booth D, Kumar A, McLean A, Schughart K.

Nat Commun. 2019 Jul 31;10(1):3422. doi: 10.1038/s41467-019-11249-y.

4.

Tmprss2 knock-out mice are resistant to H10 influenza A virus pathogenesis.

Lambertz RLO, Gerhauser I, Nehlmeier I, Leist SR, Kollmus H, Pöhlmann S, Schughart K.

J Gen Virol. 2019 Jul;100(7):1073-1078. doi: 10.1099/jgv.0.001274. Epub 2019 May 17.

PMID:
31099738
5.

Endosomal Toll-Like Receptors 7 and 9 Cooperate in Detection of Murine Gammaherpesvirus 68 Infection.

Bussey KA, Murthy S, Reimer E, Chan B, Hatesuer B, Schughart K, Glaunsinger B, Adler H, Brinkmann MM.

J Virol. 2019 Jan 17;93(3). pii: e01173-18. doi: 10.1128/JVI.01173-18. Print 2019 Feb 1.

6.

Exchange of amino acids in the H1-haemagglutinin to H3 residues is required for efficient influenza A virus replication and pathology in Tmprss2 knock-out mice.

Lambertz RLO, Pippel J, Gerhauser I, Kollmus H, Anhlan D, Hrincius ER, Krausze J, Kühn N, Schughart K.

J Gen Virol. 2018 Sep;99(9):1187-1198. doi: 10.1099/jgv.0.001128. Epub 2018 Aug 6.

7.

TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1.

Zmora P, Hoffmann M, Kollmus H, Moldenhauer AS, Danov O, Braun A, Winkler M, Schughart K, Pöhlmann S.

J Biol Chem. 2018 Sep 7;293(36):13863-13873. doi: 10.1074/jbc.RA118.001273. Epub 2018 Jul 5.

8.

Of mice and men: the host response to influenza virus infection.

Kollmus H, Pilzner C, Leist SR, Heise M, Geffers R, Schughart K.

Mamm Genome. 2018 Aug;29(7-8):446-470. doi: 10.1007/s00335-018-9750-y. Epub 2018 Jun 15.

9.

Long-Term Neuroinflammation Induced by Influenza A Virus Infection and the Impact on Hippocampal Neuron Morphology and Function.

Hosseini S, Wilk E, Michaelsen-Preusse K, Gerhauser I, Baumgärtner W, Geffers R, Schughart K, Korte M.

J Neurosci. 2018 Mar 21;38(12):3060-3080. doi: 10.1523/JNEUROSCI.1740-17.2018. Epub 2018 Feb 27.

10.

Increased virulence of a PB2/HA mutant of an avian H9N2 influenza strain after three passages in porcine differentiated airway epithelial cells.

Yang W, Lambertz RLO, Punyadarsaniya D, Leist SR, Stech J, Schughart K, Herrler G, Wu NH, Meng F.

Vet Microbiol. 2017 Nov;211:129-134. doi: 10.1016/j.vetmic.2017.10.015. Epub 2017 Oct 16.

PMID:
29102108
11.

Absence of regulator of G-protein signaling 4 does not protect against dopamine neuron dysfunction and injury in the mouse 6-hydroxydopamine lesion model of Parkinson's disease.

Ashrafi A, Garcia P, Kollmus H, Schughart K, Del Sol A, Buttini M, Glaab E.

Neurobiol Aging. 2017 Oct;58:30-33. doi: 10.1016/j.neurobiolaging.2017.06.008. Epub 2017 Jun 19.

12.

A novel immune biomarker IFI27 discriminates between influenza and bacteria in patients with suspected respiratory infection.

Tang BM, Shojaei M, Parnell GP, Huang S, Nalos M, Teoh S, O'Connor K, Schibeci S, Phu AL, Kumar A, Ho J, Meyers AFA, Keynan Y, Ball T, Pisipati A, Kumar A, Moore E, Eisen D, Lai K, Gillett M, Geffers R, Luo H, Gul F, Schreiber J, Riedel S, Booth D, McLean A, Schughart K.

Eur Respir J. 2017 Jun 15;49(6). pii: 1602098. doi: 10.1183/13993003.02098-2016. Print 2017 Jun.

13.

Host Genetic Background Strongly Affects Pulmonary microRNA Expression before and during Influenza A Virus Infection.

Preusse M, Schughart K, Pessler F.

Front Immunol. 2017 Mar 21;8:246. doi: 10.3389/fimmu.2017.00246. eCollection 2017.

14.

Mutations during the Adaptation of H9N2 Avian Influenza Virus to the Respiratory Epithelium of Pigs Enhance Sialic Acid Binding Activity and Virulence in Mice.

Yang W, Punyadarsaniya D, Lambertz RLO, Lee DCC, Liang CH, Höper D, Leist SR, Hernández-Cáceres A, Stech J, Beer M, Wu CY, Wong CH, Schughart K, Meng F, Herrler G.

J Virol. 2017 Mar 29;91(8). pii: e02125-16. doi: 10.1128/JVI.02125-16. Print 2017 Apr 15.

15.
16.

Deletion of Irf3 and Irf7 Genes in Mice Results in Altered Interferon Pathway Activation and Granulocyte-Dominated Inflammatory Responses to Influenza A Infection.

Hatesuer B, Hoang HT, Riese P, Trittel S, Gerhauser I, Elbahesh H, Geffers R, Wilk E, Schughart K.

J Innate Immun. 2017;9(2):145-161. doi: 10.1159/000450705. Epub 2016 Nov 4.

17.

Identification of specific residues in avian influenza A virus NS1 that enhance viral replication and pathogenicity in mammalian systems.

Kanrai P, Mostafa A, Madhugiri R, Lechner M, Wilk E, Schughart K, Ylösmäki L, Saksela K, Ziebuhr J, Pleschka S.

J Gen Virol. 2016 Sep;97(9):2135-2148. doi: 10.1099/jgv.0.000542. Epub 2016 Jul 12.

PMID:
27405649
18.

Genetically diverse CC-founder mouse strains replicate the human influenza gene expression signature.

Elbahesh H, Schughart K.

Sci Rep. 2016 May 19;6:26437. doi: 10.1038/srep26437.

19.

Respiratory Mucosal Proteome Quantification in Human Influenza Infections.

Marion T, Elbahesh H, Thomas PG, DeVincenzo JP, Webby R, Schughart K.

PLoS One. 2016 Apr 18;11(4):e0153674. doi: 10.1371/journal.pone.0153674. eCollection 2016.

20.

TLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency virus infection and correlates to CD4 counts and virus loads.

Low HZ, Ahrenstorf G, Pommerenke C, Habermann N, Schughart K, Ordóñez D, Stripecke R, Wilk E, Witte T.

Retrovirology. 2016 Mar 12;13:15. doi: 10.1186/s12977-016-0248-y.

21.

Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice.

Leist SR, Pilzner C, van den Brand JM, Dengler L, Geffers R, Kuiken T, Balling R, Kollmus H, Schughart K.

BMC Genomics. 2016 Feb 27;17:143. doi: 10.1186/s12864-016-2483-y.

22.

The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases.

Kühn N, Bergmann S, Kösterke N, Lambertz RLO, Keppner A, van den Brand JMA, Pöhlmann S, Weiß S, Hummler E, Hatesuer B, Schughart K.

J Virol. 2016 Apr 14;90(9):4298-4307. doi: 10.1128/JVI.02693-15. Print 2016 May.

23.

Lst1 deficiency has a minor impact on course and outcome of the host response to influenza A H1N1 infections in mice.

Leist SR, Kollmus H, Hatesuer B, Lambertz RL, Schughart K.

Virol J. 2016 Jan 27;13:17. doi: 10.1186/s12985-016-0471-0.

24.

CD11b(+)Ly6C(++)Ly6G(-) Cells with Suppressive Activity Towards T Cells Accumulate in Lungs of Influenza a Virus-Infected Mice.

Milanez-Almeida P, Ulas T, Pasztoi M, Glage S, Schughart K, Lutz MB, Schultze JL, Huehn J.

Eur J Microbiol Immunol (Bp). 2015 Nov 4;5(4):246-55. doi: 10.1556/1886.2015.00038. eCollection 2015 Dec.

25.

RNAseq expression analysis of resistant and susceptible mice after influenza A virus infection identifies novel genes associated with virus replication and important for host resistance to infection.

Wilk E, Pandey AK, Leist SR, Hatesuer B, Preusse M, Pommerenke C, Wang J, Schughart K.

BMC Genomics. 2015 Sep 2;16:655. doi: 10.1186/s12864-015-1867-8.

26.

Protection from Severe Influenza Virus Infections in Mice Carrying the Mx1 Influenza Virus Resistance Gene Strongly Depends on Genetic Background.

Shin DL, Hatesuer B, Bergmann S, Nedelko T, Schughart K.

J Virol. 2015 Oct;89(19):9998-10009. doi: 10.1128/JVI.01305-15. Epub 2015 Jul 22.

27.

Hematological parameters in the early phase of influenza A virus infection in differentially susceptible inbred mouse strains.

Preusse M, Schughart K, Wilk E, Klawonn F, Pessler F.

BMC Res Notes. 2015 Jun 6;8:225. doi: 10.1186/s13104-015-1195-8.

28.

Microarray gene expression analysis reveals major differences between Toxocara canis and Toxocara cati neurotoxocarosis and involvement of T. canis in lipid biosynthetic processes.

Janecek E, Wilk E, Schughart K, Geffers R, Strube C.

Int J Parasitol. 2015 Jun;45(7):495-503. doi: 10.1016/j.ijpara.2015.02.009. Epub 2015 Apr 3.

PMID:
25843806
29.

Segregation of a spontaneous Klrd1 (CD94) mutation in DBA/2 mouse substrains.

Shin DL, Pandey AK, Ziebarth JD, Mulligan MK, Williams RW, Geffers R, Hatesuer B, Schughart K, Wilk E.

G3 (Bethesda). 2014 Dec 17;5(2):235-9. doi: 10.1534/g3.114.015164.

30.

The interferon-induced gene Ifi27l2a is active in lung macrophages and lymphocytes after influenza A infection but deletion of Ifi27l2a in mice does not increase susceptibility to infection.

Tantawy MA, Hatesuer B, Wilk E, Dengler L, Kasnitz N, Weiß S, Schughart K.

PLoS One. 2014 Sep 3;9(9):e106392. doi: 10.1371/journal.pone.0106392. eCollection 2014.

31.

Cellular changes in blood indicate severe respiratory disease during influenza infections in mice.

Dengler L, Kühn N, Shin DL, Hatesuer B, Schughart K, Wilk E.

PLoS One. 2014 Jul 24;9(7):e103149. doi: 10.1371/journal.pone.0103149. eCollection 2014.

32.

Systems biology and systems genetics - novel innovative approaches to study host-pathogen interactions during influenza infection.

Kollmus H, Wilk E, Schughart K.

Curr Opin Virol. 2014 Jun;6:47-54. doi: 10.1016/j.coviro.2014.03.008. Epub 2014 Apr 23. Review.

33.

Systems genetics of liver fibrosis: identification of fibrogenic and expression quantitative trait loci in the BXD murine reference population.

Hall RA, Liebe R, Hochrath K, Kazakov A, Alberts R, Laufs U, Böhm M, Fischer HP, Williams RW, Schughart K, Weber SN, Lammert F.

PLoS One. 2014 Feb 28;9(2):e89279. doi: 10.1371/journal.pone.0089279. eCollection 2014.

34.

Influenza A immunomics and public health omics: the dynamic pathway interplay in host response to H1N1 infection.

Dimitrakopoulou K, Dimitrakopoulos GN, Wilk E, Tsimpouris C, Sgarbas KN, Schughart K, Bezerianos A.

OMICS. 2014 Mar;18(3):167-83. doi: 10.1089/omi.2013.0062. Epub 2014 Feb 10.

PMID:
24512282
35.

Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.

Hatesuer B, Bertram S, Mehnert N, Bahgat MM, Nelson PS, Pöhlmann S, Schughart K.

PLoS Pathog. 2013;9(12):e1003774. doi: 10.1371/journal.ppat.1003774. Epub 2013 Dec 5. Erratum in: PLoS Pathog. 2014 Sep;10(9):e1004435. Pöhlman, Stefan [corrected to Pöhlmann, Stefan].

36.

Infection- and procedure-dependent effects on pulmonary gene expression in the early phase of influenza A virus infection in mice.

Preusse M, Tantawy MA, Klawonn F, Schughart K, Pessler F.

BMC Microbiol. 2013 Dec 17;13:293. doi: 10.1186/1471-2180-13-293.

37.

IFIT2 is an effector protein of type I IFN-mediated amplification of lipopolysaccharide (LPS)-induced TNF-α secretion and LPS-induced endotoxin shock.

Siegfried A, Berchtold S, Manncke B, Deuschle E, Reber J, Ott T, Weber M, Kalinke U, Hofer MJ, Hatesuer B, Schughart K, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Weber F, Hornef MW, Autenrieth IB, Bohn E.

J Immunol. 2013 Oct 1;191(7):3913-21. doi: 10.4049/jimmunol.1203305. Epub 2013 Sep 6.

38.

The bioluminescent Listeria monocytogenes strain Xen32 is defective in flagella expression and highly attenuated in orally infected BALB/cJ mice.

Bergmann S, Rohde M, Schughart K, Lengeling A.

Gut Pathog. 2013 Jul 15;5(1):19. doi: 10.1186/1757-4749-5-19.

39.

ATR-FTIR spectroscopy reveals genomic loci regulating the tissue response in high fat diet fed BXD recombinant inbred mouse strains.

Dogan A, Lasch P, Neuschl C, Millrose MK, Alberts R, Schughart K, Naumann D, Brockmann GA.

BMC Genomics. 2013 Jun 10;14:386. doi: 10.1186/1471-2164-14-386.

40.

Meeting report of the European mouse complex genetics network SYSGENET.

Delprato A, Aransay AM, Kollmus H, Schughart K, Falcon-Perez JM.

Mamm Genome. 2013 Jun;24(5-6):190-7. doi: 10.1007/s00335-013-9458-y. Epub 2013 May 15.

PMID:
23673683
41.

Controlling complexity: the clinical relevance of mouse complex genetics.

Schughart K, Libert C; SYSGENET consortium, Kas MJ.

Eur J Hum Genet. 2013 Nov;21(11):1191-6. doi: 10.1038/ejhg.2013.79. Epub 2013 May 1. Review.

42.

Influence of internalin A murinisation on host resistance to orally acquired listeriosis in mice.

Bergmann S, Beard PM, Pasche B, Lienenklaus S, Weiss S, Gahan CG, Schughart K, Lengeling A.

BMC Microbiol. 2013 Apr 23;13:90. doi: 10.1186/1471-2180-13-90.

43.

Analysis of the lung transcriptome in Mycobacterium tuberculosis-infected mice reveals major differences in immune response pathways between TB-susceptible and resistant hosts.

Shepelkova G, Pommerenke C, Alberts R, Geffers R, Evstifeev V, Apt A, Schughart K, Wilk E.

Tuberculosis (Edinb). 2013 Mar;93(2):263-9. doi: 10.1016/j.tube.2012.11.007. Epub 2012 Dec 29.

PMID:
23276693
44.

Human disease: Strength to strength for mouse models.

Schughart K, Libert C, Kas MJ.

Nature. 2012 Dec 6;492(7427):41. doi: 10.1038/492041c. No abstract available.

PMID:
23222600
45.

PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells.

He F, Chen H, Probst-Kepper M, Geffers R, Eifes S, Del Sol A, Schughart K, Zeng AP, Balling R.

Mol Syst Biol. 2012;8:624. doi: 10.1038/msb.2012.56.

46.

Equivalence of self- and staff-collected nasal swabs for the detection of viral respiratory pathogens.

Akmatov MK, Gatzemeier A, Schughart K, Pessler F.

PLoS One. 2012;7(11):e48508. doi: 10.1371/journal.pone.0048508. Epub 2012 Nov 14.

47.

Structural and functional concepts in current mouse phenotyping and archiving facilities.

Kollmus H, Post R, Brielmeier M, Fernández J, Fuchs H, McKerlie C, Montoliu L, Otaegui PJ, Rebelo M, Riedesel H, Ruberte J, Sedlacek R, de Angelis MH, Schughart K.

J Am Assoc Lab Anim Sci. 2012 Jul;51(4):418-35.

48.

Immunization with live virus vaccine protects highly susceptible DBA/2J mice from lethal influenza A H1N1 infection.

Dengler L, May M, Wilk E, Bahgat MM, Schughart K.

Virol J. 2012 Sep 19;9:212. doi: 10.1186/1743-422X-9-212.

49.

Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner.

Nedelko T, Kollmus H, Klawonn F, Spijker S, Lu L, Heßman M, Alberts R, Williams RW, Schughart K.

BMC Genomics. 2012 Aug 20;13:411. doi: 10.1186/1471-2164-13-411.

50.

Global transcriptome analysis in influenza-infected mouse lungs reveals the kinetics of innate and adaptive host immune responses.

Pommerenke C, Wilk E, Srivastava B, Schulze A, Novoselova N, Geffers R, Schughart K.

PLoS One. 2012;7(7):e41169. doi: 10.1371/journal.pone.0041169. Epub 2012 Jul 17.

Supplemental Content

Loading ...
Support Center