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Induction of activated T follicular helper cells is critical for anti-FVIII inhibitor development in hemophilia A mice.

Jing W, Chen J, Cai Y, Chen Y, Schroeder JA, Johnson BD, Cui W, Shi Q.

Blood Adv. 2019 Oct 22;3(20):3099-3110. doi: 10.1182/bloodadvances.2019000650.


Nongenotoxic antibody-drug conjugate conditioning enables safe and effective platelet gene therapy of hemophilia A mice.

Gao C, Schroeder JA, Xue F, Jing W, Cai Y, Scheck A, Subramaniam S, Rao S, Weiler H, Czechowicz A, Shi Q.

Blood Adv. 2019 Sep 24;3(18):2700-2711. doi: 10.1182/bloodadvances.2019000516.


The impact of GPIbα on platelet-targeted FVIII gene therapy in hemophilia A mice with pre-existing anti-FVIII immunity.

Chen J, Schroeder JA, Luo X, Montgomery RR, Shi Q.

J Thromb Haemost. 2019 Mar;17(3):449-459. doi: 10.1111/jth.14379. Epub 2019 Feb 3.


Platelet Gene Therapy Promotes Targeted Peripheral Tolerance by Clonal Deletion and Induction of Antigen-Specific Regulatory T Cells.

Luo X, Chen J, Schroeder JA, Allen KP, Baumgartner CK, Malarkannan S, Hu J, Williams CB, Shi Q.

Front Immunol. 2018 Sep 6;9:1950. doi: 10.3389/fimmu.2018.01950. eCollection 2018.


Multimodal Imaging Study of Gadolinium Presence in Rat Cerebellum: Differences Between Gd Chelates, Presence in the Virchow-Robin Space, Association With Lipofuscin, and Hypotheses About Distribution Pathway.

Rasschaert M, Schroeder JA, Wu TD, Marco S, Emerit A, Siegmund H, Fischer C, Fretellier N, Idée JM, Corot C, Brochhausen C, Guerquin-Kern JL.

Invest Radiol. 2018 Sep;53(9):518-528. doi: 10.1097/RLI.0000000000000490.


miR-9a mediates the role of Lethal giant larvae as an epithelial growth inhibitor in Drosophila.

Daniel SG, Russ AD, Guthridge KM, Raina AI, Estes PS, Parsons LM, Richardson HE, Schroeder JA, Zarnescu DC.

Biol Open. 2018 Jan 26;7(1). pii: bio027391. doi: 10.1242/bio.027391.


The "chain of lakes" sign.

Schroeder JA, Dyer RB, Holbert BL.

Abdom Radiol (NY). 2018 Jul;43(7):1842-1844. doi: 10.1007/s00261-017-1369-z. Review. No abstract available.


The impact of von Willebrand factor on factor VIII memory immune responses.

Chen J, Schroeder JA, Luo X, Shi Q.

Blood Adv. 2017 Aug 22;1(19):1565-1574. doi: 10.1182/bloodadvances.2017009209. Epub 2017 Aug 18.


Application of laboratory and digital techniques for visual enhancement during the ultrastructural assessment of cilia.

Schroeder JA.

Ultrastruct Pathol. 2017 Nov-Dec;41(6):399-407. doi: 10.1080/01913123.2017.1363335. Epub 2017 Sep 11. Review.


Immune tolerance induced by platelet-targeted factor VIII gene therapy in hemophilia A mice is CD4 T cell mediated.

Chen Y, Luo X, Schroeder JA, Chen J, Baumgartner CK, Hu J, Shi Q.

J Thromb Haemost. 2017 Oct;15(10):1994-2004. doi: 10.1111/jth.13800. Epub 2017 Sep 11.


TGF-β1 along with other platelet contents augments Treg cells to suppress anti-FVIII immune responses in hemophilia A mice.

Haribhai D, Luo X, Chen J, Jia S, Shi L, Schroeder JA, Weiler H, Aster RH, Hessner MJ, Hu J, Williams CB, Shi Q.

Blood Adv. 2016 Dec 13;1(2):139-151. doi: 10.1182/bloodadvances.2016001453.


Child and case influences on recidivism in a statewide dissemination of Multisystemic Therapy for juvenile offenders.

Connell CM, Steeger CM, Schroeder JA, Franks RP, Tebes JK.

Crim Justice Behav. 2016 Oct;43(10):1330-1346. doi: 10.1177/0093854816641715. Epub 2016 May 9.


Proteolysis of plasminogen activator inhibitor-1 by Yersinia pestis remodulates the host environment to promote virulence.

Eddy JL, Schroeder JA, Zimbler DL, Caulfield AJ, Lathem WW.

J Thromb Haemost. 2016 Sep;14(9):1833-43. doi: 10.1111/jth.13408. Epub 2016 Aug 19.


The immunogenicity of platelet-derived FVIII in hemophilia A mice with or without preexisting anti-FVIII immunity.

Chen Y, Schroeder JA, Chen J, Luo X, Baumgartner CK, Montgomery RR, Hu J, Shi Q.

Blood. 2016 Mar 10;127(10):1346-54. doi: 10.1182/blood-2015-08-662916. Epub 2015 Dec 14.


Inactivation of Peroxiredoxin 6 by the Pla Protease of Yersinia pestis.

Zimbler DL, Eddy JL, Schroeder JA, Lathem WW.

Infect Immun. 2015 Nov 9;84(1):365-74. doi: 10.1128/IAI.01168-15. Print 2016 Jan.


Impact of the Pla protease substrate α2-antiplasmin on the progression of primary pneumonic plague.

Eddy JL, Schroeder JA, Zimbler DL, Bellows LE, Lathem WW.

Infect Immun. 2015 Dec;83(12):4837-47. doi: 10.1128/IAI.01086-15. Epub 2015 Oct 5.


Early emergence of Yersinia pestis as a severe respiratory pathogen.

Zimbler DL, Schroeder JA, Eddy JL, Lathem WW.

Nat Commun. 2015 Jun 30;6:7487. doi: 10.1038/ncomms8487.


The important role of von Willebrand factor in platelet-derived FVIII gene therapy for murine hemophilia A in the presence of inhibitory antibodies.

Shi Q, Schroeder JA, Kuether EL, Montgomery RR.

J Thromb Haemost. 2015 Jul;13(7):1301-9. doi: 10.1111/jth.13001. Epub 2015 Jun 11.


Taking the next step forward - Diagnosing inherited infantile cholestatic disorders with next generation sequencing.

Herbst SM, Schirmer S, Posovszky C, Jochum F, Rödl T, Schroeder JA, Barth TF, Hehr U, Melter M, Vermehren J.

Mol Cell Probes. 2015 Oct;29(5):291-8. doi: 10.1016/j.mcp.2015.03.001. Epub 2015 Mar 13.


Gadolinium deposits could influence the course of encapsulating peritoneal sclerosis.

Latus J, Goffin E, Schroeder JA, Fritz P, Ott G, Ulmer C, Steurer W, Kimmel M, Biegger D, Segerer S, Alscher MD, Braun N.

Perit Dial Int. 2014 Jul-Aug;34(5):561-5. doi: 10.3747/pdi.2013.00137. No abstract available.


Clavulanic acid reduces rewarding, hyperthermic and locomotor-sensitizing effects of morphine in rats: a new indication for an old drug?

Schroeder JA, Tolman NG, McKenna FF, Watkins KL, Passeri SM, Hsu AH, Shinn BR, Rawls SM.

Drug Alcohol Depend. 2014 Sep 1;142:41-5. doi: 10.1016/j.drugalcdep.2014.05.012. Epub 2014 Jun 2.


In vivo enrichment of genetically manipulated platelets corrects the murine hemophilic phenotype and induces immune tolerance even using a low multiplicity of infection.

Schroeder JA, Chen Y, Fang J, Wilcox DA, Shi Q.

J Thromb Haemost. 2014 Aug;12(8):1283-93. doi: 10.1111/jth.12633. Epub 2014 Jul 17.


Endothelial dysfunction and altered mechanical and structural properties of resistance arteries in a murine model of graft-versus-host disease.

Schmid PM, Bouazzaoui A, Doser K, Schmid K, Hoffmann P, Schroeder JA, Riegger GA, Holler E, Endemann DH.

Biol Blood Marrow Transplant. 2014 Oct;20(10):1493-500. doi: 10.1016/j.bbmt.2014.05.002. Epub 2014 May 9.


Inadequate corticosterone levels relative to arthritic inflammation are accompanied by altered mitochondria/cholesterol breakdown in adrenal cortex: a steroid-inhibiting role of IL-1β in rats.

Wolff C, Krinner K, Schroeder JA, Straub RH.

Ann Rheum Dis. 2015 Oct;74(10):1890-7. doi: 10.1136/annrheumdis-2013-203885. Epub 2014 May 7.


Posttranscriptional regulation of the Yersinia pestis cyclic AMP receptor protein Crp and impact on virulence.

Lathem WW, Schroeder JA, Bellows LE, Ritzert JT, Koo JT, Price PA, Caulfield AJ, Goldman WE.

MBio. 2014 Feb 11;5(1):e01038-13. doi: 10.1128/mBio.01038-13.


Platelet gene therapy corrects the hemophilic phenotype in immunocompromised hemophilia A mice transplanted with genetically manipulated human cord blood stem cells.

Shi Q, Kuether EL, Chen Y, Schroeder JA, Fahs SA, Montgomery RR.

Blood. 2014 Jan 16;123(3):395-403. doi: 10.1182/blood-2013-08-520478. Epub 2013 Nov 22.


Inactive ERBB receptors cooperate with reactive oxygen species to suppress cancer progression.

Hart MR, Su HY, Broka D, Goverdhan A, Schroeder JA.

Mol Ther. 2013 Nov;21(11):1996-2007. doi: 10.1038/mt.2013.196. Epub 2013 Oct 1.


Male infertility: assessment of juvenile testicular dysfunction and risk for malignancy in cryptorchid boys based on resin section evaluation.

Schroeder JA, Siegmund HI, Roesch W, Hadziselimovic F, Hofstaedter F.

Ultrastruct Pathol. 2013 Oct;37(5):373-7. doi: 10.3109/01913123.2013.818603.


Platelet gene therapy by lentiviral gene delivery to hematopoietic stem cells restores hemostasis and induces humoral immune tolerance in FIX(null) mice.

Chen Y, Schroeder JA, Kuether EL, Zhang G, Shi Q.

Mol Ther. 2014 Jan;22(1):169-77. doi: 10.1038/mt.2013.197. Epub 2013 Aug 23.


MUC1 and metastatic cancer: expression, function and therapeutic targeting.

Horm TM, Schroeder JA.

Cell Adh Migr. 2013 Mar-Apr;7(2):187-98. doi: 10.4161/cam.23131. Epub 2013 Jan 9. Review.


MUC1 drives c-Met-dependent migration and scattering.

Horm TM, Bitler BG, Broka DM, Louderbough JM, Schroeder JA.

Mol Cancer Res. 2012 Dec;10(12):1544-54. doi: 10.1158/1541-7786.MCR-12-0296. Epub 2012 Nov 27.


Hugl1 and Hugl2 in mammary epithelial cells: polarity, proliferation, and differentiation.

Russ A, Louderbough JM, Zarnescu D, Schroeder JA.

PLoS One. 2012;7(10):e47734. doi: 10.1371/journal.pone.0047734. Epub 2012 Oct 23.


Factor VIII inhibitors: von Willebrand factor makes a difference in vitro and in vivo.

Shi Q, Kuether EL, Schroeder JA, Perry CL, Fahs SA, Cox Gill J, Montgomery RR.

J Thromb Haemost. 2012 Nov;10(11):2328-37. doi: 10.1111/j.1538-7836.2012.04902.x.


New genetic lineages, host associations and circulation pathways of Neorickettsia endosymbionts of digeneans.

Tkach VV, Schroeder JA, Greiman SE, Vaughan JA.

Acta Parasitol. 2012 Sep;57(3):285-92. doi: 10.2478/s11686-012-0043-4. Epub 2012 Aug 9.


Lentivirus-mediated platelet gene therapy of murine hemophilia A with pre-existing anti-factor VIII immunity.

Kuether EL, Schroeder JA, Fahs SA, Cooley BC, Chen Y, Montgomery RR, Wilcox DA, Shi Q.

J Thromb Haemost. 2012 Aug;10(8):1570-80. doi: 10.1111/j.1538-7836.2012.04791.x.


The phosphodiesterase inhibitor isobutylmethylxanthine attenuates behavioral sensitization to cocaine.

Schroeder JA, Ruta JD, Gordon JS, Rodrigues AS, Foote CC.

Behav Pharmacol. 2012 Jun;23(3):310-4. doi: 10.1097/FBP.0b013e3283536d04.


CD44 Promotes Epithelial Mammary Gland Development and Exhibits Altered Localization during Cancer Progression.

Louderbough JM, Brown JA, Nagle RB, Schroeder JA.

Genes Cancer. 2011 Aug;2(8):771-81. doi: 10.1177/1947601911428223.


Intravascular recovery of VWF and FVIII following intraperitoneal injection and differences from intravenous and subcutaneous injection in mice.

Shi Q, Kuether EL, Schroeder JA, Fahs SA, Montgomery RR.

Haemophilia. 2012 Jul;18(4):639-46. doi: 10.1111/j.1365-2516.2011.02735.x. Epub 2012 Jan 4.


Correction of murine Bernard-Soulier syndrome by lentivirus-mediated gene therapy.

Kanaji S, Kuether EL, Fahs SA, Schroeder JA, Ware J, Montgomery RR, Shi Q.

Mol Ther. 2012 Mar;20(3):625-32. doi: 10.1038/mt.2011.231. Epub 2011 Nov 1.


Glutamate transporter activation enhances nicotine antinociception and attenuates nicotine analgesic tolerance.

Schroeder JA, Quick KF, Landry PM, Rawls SM.

Neuroreport. 2011 Dec 21;22(18):970-3. doi: 10.1097/WNR.0b013e32834d87eb.


Understanding the dual nature of CD44 in breast cancer progression.

Louderbough JM, Schroeder JA.

Mol Cancer Res. 2011 Dec;9(12):1573-86. doi: 10.1158/1541-7786.MCR-11-0156. Epub 2011 Oct 4. Review.


Cell receptor and surface ligand density effects on dynamic states of adhering circulating tumor cells.

Zheng X, Cheung LS, Schroeder JA, Jiang L, Zohar Y.

Lab Chip. 2011 Oct 21;11(20):3431-9. doi: 10.1039/c1lc20455f. Epub 2011 Aug 19.


A high-performance microsystem for isolating circulating tumor cells.

Zheng X, Cheung LS, Schroeder JA, Jiang L, Zohar Y.

Lab Chip. 2011 Oct 7;11(19):3269-76. doi: 10.1039/c1lc20331b. Epub 2011 Aug 11.


Pilot study on the effects of dietary conjugated linoleic acid on tumorigenesis and gene expression in PyMT transgenic mice.

Flowers M, Schroeder JA, Borowsky AD, Besselsen DG, Thomson CA, Pandey R, Thompson PA.

Carcinogenesis. 2010 Sep;31(9):1642-9. doi: 10.1093/carcin/bgq148. Epub 2010 Jul 11.


Do differing types of victimization and coping strategies influence the type of social reactions experienced by current victims of intimate partner violence?

Sullivan TP, Schroeder JA, Dudley DN, Dixon JM.

Violence Against Women. 2010 Jun;16(6):638-57. doi: 10.1177/1077801210370027.


MUC1 regulates nuclear localization and function of the epidermal growth factor receptor.

Bitler BG, Goverdhan A, Schroeder JA.

J Cell Sci. 2010 May 15;123(Pt 10):1716-23. doi: 10.1242/jcs.062661. Epub 2010 Apr 20.


Matrix hyaluronan alters epidermal growth factor receptor-dependent cell morphology.

Louderbough JM, Lopez JI, Schroeder JA.

Cell Adh Migr. 2010 Jan-Mar;4(1):26-31. Epub 2010 Jan 29.


Absence of gadolinium deposits in the peritoneal membrane of patients with encapsulating peritoneal sclerosis.

Goffin E, Schroeder JA, Weingart C, Decleire PY, Cosyns JP.

Nephrol Dial Transplant. 2010 Apr;25(4):1334-9. doi: 10.1093/ndt/gfp664. Epub 2009 Dec 10.


Anti-cancer therapies that utilize cell penetrating peptides.

Bitler BG, Schroeder JA.

Recent Pat Anticancer Drug Discov. 2010 Jun;5(2):99-108. Review.


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