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Items: 37

1.

Neuroepigenetic signatures of age and sex in the living human brain.

Gilbert TM, Zürcher NR, Catanese MC, Tseng CJ, Di Biase MA, Lyall AE, Hightower BG, Parmar AJ, Bhanot A, Wu CJ, Hibert ML, Kim M, Mahmood U, Stufflebeam SM, Schroeder FA, Wang C, Roffman JL, Holt DJ, Greve DN, Pasternak O, Kubicki M, Wey HY, Hooker JM.

Nat Commun. 2019 Jul 3;10(1):2945. doi: 10.1038/s41467-019-11031-0.

2.

PET neuroimaging reveals histone deacetylase dysregulation in schizophrenia.

Gilbert TM, Zürcher NR, Wu CJ, Bhanot A, Hightower BG, Kim M, Albrecht DS, Wey HY, Schroeder FA, Rodriguez-Thompson A, Morin TM, Hart KL, Pellegrini AM, Riley MM, Wang C, Stufflebeam SM, Haggarty SJ, Holt DJ, Loggia ML, Perlis RH, Brown HE, Roffman JL, Hooker JM.

J Clin Invest. 2019 Jan 2;129(1):364-372. doi: 10.1172/JCI123743. Epub 2018 Dec 10.

3.

Discrepancies in Kappa Opioid Agonist Binding Revealed through PET Imaging.

Placzek MS, Schroeder FA, Che T, Wey HY, Neelamegam R, Wang C, Roth BL, Hooker JM.

ACS Chem Neurosci. 2019 Jan 16;10(1):384-395. doi: 10.1021/acschemneuro.8b00293. Epub 2018 Oct 17.

PMID:
30212182
4.

Functionally Biased D2R Antagonists: Targeting the β-Arrestin Pathway to Improve Antipsychotic Treatment.

Weïwer M, Xu Q, Gale JP, Lewis M, Campbell AJ, Schroeder FA, Van de Bittner GC, Walk M, Amaya A, Su P, D Ordevic L, Sacher JR, Skepner A, Fei D, Dennehy K, Nguyen S, Faloon PW, Perez J, Cottrell JR, Liu F, Palmer M, Pan JQ, Hooker JM, Zhang YL, Scolnick E, Wagner FF, Holson EB.

ACS Chem Biol. 2018 Apr 20;13(4):1038-1047. doi: 10.1021/acschembio.8b00168. Epub 2018 Mar 14.

PMID:
29485852
5.

In Vivo [18F]GE-179 Brain Signal Does Not Show NMDA-Specific Modulation with Drug Challenges in Rodents and Nonhuman Primates.

Schoenberger M, Schroeder FA, Placzek MS, Carter RL, Rosen BR, Hooker JM, Sander CY.

ACS Chem Neurosci. 2018 Feb 21;9(2):298-305. doi: 10.1021/acschemneuro.7b00327. Epub 2017 Nov 14.

6.

HDAC6 Brain Mapping with [18F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination.

Strebl MG, Campbell AJ, Zhao WN, Schroeder FA, Riley MM, Chindavong PS, Morin TM, Haggarty SJ, Wagner FF, Ritter T, Hooker JM.

ACS Cent Sci. 2017 Sep 27;3(9):1006-1014. doi: 10.1021/acscentsci.7b00274. Epub 2017 Sep 6.

7.

Imaging cardiac SCN5A using the novel F-18 radiotracer radiocaine.

Hooker JM, Strebl MG, Schroeder FA, Wey HY, Ambardekar AV, McKinsey TA, Schoenberger M.

Sci Rep. 2017 Feb 16;7:42136. doi: 10.1038/srep42136.

8.

Nasal neuron PET imaging quantifies neuron generation and degeneration.

Van de Bittner GC, Riley MM, Cao L, Ehses J, Herrick SP, Ricq EL, Wey HY, O'Neill MJ, Ahmed Z, Murray TK, Smith JE, Wang C, Schroeder FA, Albers MW, Hooker JM.

J Clin Invest. 2017 Feb 1;127(2):681-694. doi: 10.1172/JCI89162. Epub 2017 Jan 23.

9.

Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia.

Schroeder FA, Gilbert TM, Feng N, Taillon BD, Volkow ND, Innis RB, Hooker JM, Lipska BK.

ACS Chem Neurosci. 2017 Mar 15;8(3):662-668. doi: 10.1021/acschemneuro.6b00372. Epub 2016 Dec 13.

10.

Development of New Positron Emission Tomography Radiotracer for BET Imaging.

Wang C, Schroeder FA, Hooker JM.

ACS Chem Neurosci. 2017 Jan 18;8(1):17-21. doi: 10.1021/acschemneuro.6b00288. Epub 2016 Nov 10.

PMID:
27806195
11.

Insights into neuroepigenetics through human histone deacetylase PET imaging.

Wey HY, Gilbert TM, Zürcher NR, She A, Bhanot A, Taillon BD, Schroeder FA, Wang C, Haggarty SJ, Hooker JM.

Sci Transl Med. 2016 Aug 10;8(351):351ra106. doi: 10.1126/scitranslmed.aaf7551.

12.

A Novel Radiotracer for Imaging Monoacylglycerol Lipase in the Brain Using Positron Emission Tomography.

Wang C, Placzek MS, Van de Bittner GC, Schroeder FA, Hooker JM.

ACS Chem Neurosci. 2016 Apr 20;7(4):484-9. doi: 10.1021/acschemneuro.5b00293. Epub 2016 Jan 6.

PMID:
26694017
13.

Development of a Fluorinated Class-I HDAC Radiotracer Reveals Key Chemical Determinants of Brain Penetrance.

Strebl MG, Wang C, Schroeder FA, Placzek MS, Wey HY, Van de Bittner GC, Neelamegam R, Hooker JM.

ACS Chem Neurosci. 2016 May 18;7(5):528-33. doi: 10.1021/acschemneuro.5b00297. Epub 2015 Dec 21.

14.

Kinetic Analysis and Quantification of [¹¹C]Martinostat for in Vivo HDAC Imaging of the Brain.

Wey HY, Wang C, Schroeder FA, Logan J, Price JC, Hooker JM.

ACS Chem Neurosci. 2015 May 20;6(5):708-15. doi: 10.1021/acschemneuro.5b00066. Epub 2015 Mar 25.

15.

In vivo imaging of histone deacetylases (HDACs) in the central nervous system and major peripheral organs.

Wang C, Schroeder FA, Wey HY, Borra R, Wagner FF, Reis S, Kim SW, Holson EB, Haggarty SJ, Hooker JM.

J Med Chem. 2014 Oct 9;57(19):7999-8009. doi: 10.1021/jm500872p. Epub 2014 Sep 18.

16.

PET imaging demonstrates histone deacetylase target engagement and clarifies brain penetrance of known and novel small molecule inhibitors in rat.

Schroeder FA, Wang C, Van de Bittner GC, Neelamegam R, Takakura WR, Karunakaran A, Wey HY, Reis SA, Gale J, Zhang YL, Holson EB, Haggarty SJ, Hooker JM.

ACS Chem Neurosci. 2014 Oct 15;5(10):1055-62. doi: 10.1021/cn500162j. Epub 2014 Sep 19.

17.

Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.

McGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G, Wolf A, Schroeder FA, Osiecki L, O'Dushlaine C, Kirby A, Illmann C, Haddad S, Gallagher P, Fagerness JA, Barr CL, Bellodi L, Benarroch F, Bienvenu OJ, Black DW, Bloch MH, Bruun RD, Budman CL, Camarena B, Cath DC, Cavallini MC, Chouinard S, Coric V, Cullen B, Delorme R, Denys D, Derks EM, Dion Y, Rosário MC, Eapen V, Evans P, Falkai P, Fernandez TV, Garrido H, Geller D, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Heiman GA, Hemmings SM, Herrera LD, Hounie AG, Jankovic J, Kennedy JL, King RA, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Lochner C, Lowe TL, Lyon GJ, Macciardi F, Maier W, McCracken JT, McMahon W, Murphy DL, Naarden AL, Neale BM, Nurmi E, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Reus VI, Richter MA, Riddle M, Robertson MM, Rosenberg D, Rouleau GA, Ruhrmann S, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Tischfield JA, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Wendland JR, Shugart YY, Miguel EC, Nicolini H, Oostra BA, Moessner R, Wagner M, Ruiz-Linares A, Heutink P, Nestadt G, Freimer N, Petryshen T, Posthuma D, Jenike MA, Cox NJ, Hanna GL, Brentani H, Scherer SW, Arnold PD, Stewart SE, Mathews CA, Knowles JA, Cook EH, Pauls DL, Wang K, Scharf JM.

J Am Acad Child Adolesc Psychiatry. 2014 Aug;53(8):910-9. doi: 10.1016/j.jaac.2014.04.022. Epub 2014 Jun 24.

18.

First D1-like receptor PET imaging of the rat and primate kidney: implications for human disease monitoring.

Granda ML, Schroeder FA, Borra RH, Schauer N, Aisaborhale E, Guimaraes AR, Hooker JM.

Am J Physiol Renal Physiol. 2014 Jul 1;307(1):F116-21. doi: 10.1152/ajprenal.00111.2014. Epub 2014 May 7.

19.

Imaging evaluation of 5HT2C agonists, [(11)C]WAY-163909 and [(11)C]vabicaserin, formed by Pictet-Spengler cyclization.

Neelamegam R, Hellenbrand T, Schroeder FA, Wang C, Hooker JM.

J Med Chem. 2014 Feb 27;57(4):1488-94. doi: 10.1021/jm401802f. Epub 2014 Feb 12.

20.

Design, synthesis, and evaluation of hydroxamic acid-based molecular probes for in vivo imaging of histone deacetylase (HDAC) in brain.

Wang C, Eessalu TE, Barth VN, Mitch CH, Wagner FF, Hong Y, Neelamegam R, Schroeder FA, Holson EB, Haggarty SJ, Hooker JM.

Am J Nucl Med Mol Imaging. 2013 Dec 15;4(1):29-38. eCollection 2013.

21.

Visualizing epigenetics: current advances and advantages in HDAC PET imaging techniques.

Wang C, Schroeder FA, Hooker JM.

Neuroscience. 2014 Apr 4;264:186-97. doi: 10.1016/j.neuroscience.2013.09.018. Epub 2013 Sep 17. Review.

22.

A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests.

Schroeder FA, Lewis MC, Fass DM, Wagner FF, Zhang YL, Hennig KM, Gale J, Zhao WN, Reis S, Barker DD, Berry-Scott E, Kim SW, Clore EL, Hooker JM, Holson EB, Haggarty SJ, Petryshen TL.

PLoS One. 2013 Aug 14;8(8):e71323. doi: 10.1371/journal.pone.0071323. eCollection 2013.

23.

Evaluation of potential PET imaging probes for the orexin 2 receptors.

Wang C, Wilson CM, Moseley CK, Carlin SM, Hsu S, Arabasz G, Schroeder FA, Sander CY, Hooker JM.

Nucl Med Biol. 2013 Nov;40(8):1000-5. doi: 10.1016/j.nucmedbio.2013.07.001. Epub 2013 Aug 15.

24.

FDG-PET imaging reveals local brain glucose utilization is altered by class I histone deacetylase inhibitors.

Schroeder FA, Chonde DB, Riley MM, Moseley CK, Granda ML, Wilson CM, Wagner FF, Zhang YL, Gale J, Holson EB, Haggarty SJ, Hooker JM.

Neurosci Lett. 2013 Aug 29;550:119-24. doi: 10.1016/j.neulet.2013.06.016. Epub 2013 Jun 25.

25.

Epigenetic mechanisms in mood disorders: targeting neuroplasticity.

Fass DM, Schroeder FA, Perlis RH, Haggarty SJ.

Neuroscience. 2014 Apr 4;264:112-30. doi: 10.1016/j.neuroscience.2013.01.041. Epub 2013 Jan 30. Review.

26.

Setdb1 histone methyltransferase regulates mood-related behaviors and expression of the NMDA receptor subunit NR2B.

Jiang Y, Jakovcevski M, Bharadwaj R, Connor C, Schroeder FA, Lin CL, Straubhaar J, Martin G, Akbarian S.

J Neurosci. 2010 May 26;30(21):7152-67. doi: 10.1523/JNEUROSCI.1314-10.2010.

27.

Biomechanical advantages of triple-loaded suture anchors compared with double-row rotator cuff repairs.

Barber FA, Herbert MA, Schroeder FA, Aziz-Jacobo J, Mays MM, Rapley JH.

Arthroscopy. 2010 Mar;26(3):316-23. doi: 10.1016/j.arthro.2009.07.019. Epub 2009 Dec 29.

PMID:
20206040
28.

Biomechanical testing of new meniscal repair techniques containing ultra high-molecular weight polyethylene suture.

Barber FA, Herbert MA, Schroeder FA, Aziz-Jacobo J, Sutker MJ.

Arthroscopy. 2009 Sep;25(9):959-67. doi: 10.1016/j.arthro.2009.03.020.

PMID:
19732633
29.

Cocaine-induced metabolic activation in cortico-limbic circuitry is increased after exposure to the histone deacetylase inhibitor, sodium butyrate.

Febo M, Akbarian S, Schroeder FA, Ferris CF.

Neurosci Lett. 2009 Nov 20;465(3):267-71. doi: 10.1016/j.neulet.2009.07.065. Epub 2009 Jul 26.

30.

FasT-Fix meniscal repair: mid-term results.

Barber FA, Schroeder FA, Oro FB, Beavis RC.

Arthroscopy. 2008 Dec;24(12):1342-8. doi: 10.1016/j.arthro.2008.08.001. Epub 2008 Oct 10.

PMID:
19038704
31.

Shrimp winch injuries.

Schroeder FA, Viegas SF, Carmichael K.

J Trauma. 2008 Jul;65(1):142-6. doi: 10.1097/TA.0b013e3180a02ee0.

PMID:
18580527
32.

Drug-induced activation of dopamine D(1) receptor signaling and inhibition of class I/II histone deacetylase induce chromatin remodeling in reward circuitry and modulate cocaine-related behaviors.

Schroeder FA, Penta KL, Matevossian A, Jones SR, Konradi C, Tapper AR, Akbarian S.

Neuropsychopharmacology. 2008 Nov;33(12):2981-92. doi: 10.1038/npp.2008.15. Epub 2008 Feb 20.

33.

Proximal femoral neck penetration after flexible intramedullary nailing for pediatric femur fractures: a rare complication.

Carmichael KD, Schroeder FA.

J Child Orthop. 2007 Oct;1(4):243-7. doi: 10.1007/s11832-007-0038-0. Epub 2007 Aug 4.

34.

Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse.

Schroeder FA, Lin CL, Crusio WE, Akbarian S.

Biol Psychiatry. 2007 Jul 1;62(1):55-64. Epub 2006 Aug 30.

PMID:
16945350
35.

Dopamine D2-like antagonists induce chromatin remodeling in striatal neurons through cyclic AMP-protein kinase A and NMDA receptor signaling.

Li J, Guo Y, Schroeder FA, Youngs RM, Schmidt TW, Ferris C, Konradi C, Akbarian S.

J Neurochem. 2004 Sep;90(5):1117-31.

36.

CONGENITAL MUSCULAR HYPERTROPHY. AN ASSOCIATION WITH INCREASED URINARY MUCOPOLYSACCHARIDES.

SILVER HK, SCHROEDER FA.

Am J Dis Child. 1964 Oct;108:406-12. No abstract available.

PMID:
14186661
37.

[PALLIATIVE GENERAL AND LOCAL TREATMENT OF MALIGNANT TUMORS WITH TRENIMON].

LINDENSCHMIDT O, SCHROEDER FA.

Zentralbl Chir. 1964 Aug 1;89:1178-9. German. No abstract available.

PMID:
14250377

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