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Items: 31


SerpinB2 inhibits migration and promotes a resolution phase signature in large peritoneal macrophages.

Schroder WA, Hirata TD, Le TT, Gardner J, Boyle GM, Ellis J, Nakayama E, Pathirana D, Nakaya HI, Suhrbier A.

Sci Rep. 2019 Aug 27;9(1):12421. doi: 10.1038/s41598-019-48741-w.


SerpinB2 deficiency in mice reduces bleeding times via dysregulated platelet activation.

Schroder WA, Le TT, Gardner J, Andrews RK, Gardiner EE, Callaway L, Suhrbier A.

Platelets. 2019;30(5):658-663. doi: 10.1080/09537104.2018.1535702. Epub 2018 Nov 2.


Lower temperatures reduce type I interferon activity and promote alphaviral arthritis.

Prow NA, Tang B, Gardner J, Le TT, Taylor A, Poo YS, Nakayama E, Hirata TDC, Nakaya HI, Slonchak A, Mukhopadhyay P, Mahalingam S, Schroder WA, Klimstra W, Suhrbier A.

PLoS Pathog. 2017 Dec 27;13(12):e1006788. doi: 10.1371/journal.ppat.1006788. eCollection 2017 Dec.


RNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammation.

Wilson JA, Prow NA, Schroder WA, Ellis JJ, Cumming HE, Gearing LJ, Poo YS, Taylor A, Hertzog PJ, Di Giallonardo F, Hueston L, Le Grand R, Tang B, Le TT, Gardner J, Mahalingam S, Roques P, Bird PI, Suhrbier A.

PLoS Pathog. 2017 Feb 16;13(2):e1006155. doi: 10.1371/journal.ppat.1006155. eCollection 2017 Feb.


Melanocyte transformation requires complete loss of all pocket protein function via a mechanism that mitigates the need for MAPK pathway activation.

Tonks ID, Mukhopadhyay P, Schroder WA, Sorolla A, Mould AW, Handoko HY, Ferguson B, Muller HK, Keith P, Hayward NK, Walker GJ, Kay GF.

Oncogene. 2017 Jun 29;36(26):3789-3795. doi: 10.1038/onc.2016.511. Epub 2017 Feb 13.


SerpinB2 Deficiency Results in a Stratum Corneum Defect and Increased Sensitivity to Topically Applied Inflammatory Agents.

Schroder WA, Anraku I, Le TT, Hirata TD, Nakaya HI, Major L, Ellis JJ, Suhrbier A.

Am J Pathol. 2016 Jun;186(6):1511-23. doi: 10.1016/j.ajpath.2016.02.017. Epub 2016 Apr 22.


IL-1 Contributes to the Anti-Cancer Efficacy of Ingenol Mebutate.

Le TT, Skak K, Schroder K, Schroder WA, Boyle GM, Pierce CJ, Suhrbier A.

PLoS One. 2016 Apr 21;11(4):e0153975. doi: 10.1371/journal.pone.0153975. eCollection 2016.


Infectious Chikungunya Virus in the Saliva of Mice, Monkeys and Humans.

Gardner J, Rudd PA, Prow NA, Belarbi E, Roques P, Larcher T, Gresh L, Balmaseda A, Harris E, Schroder WA, Suhrbier A.

PLoS One. 2015 Oct 8;10(10):e0139481. doi: 10.1371/journal.pone.0139481. eCollection 2015.


Effective cutaneous vaccination using an inactivated chikungunya virus vaccine delivered by Foroderm.

Rudd PA, Raphael AP, Yamada M, Nufer KL, Gardner J, Le TT, Prow NA, Dang N, Schroder WA, Prow TW, Suhrbier A.

Vaccine. 2015 Sep 22;33(39):5172-80. doi: 10.1016/j.vaccine.2015.07.099. Epub 2015 Aug 18.


SerpinB2 (PAI-2) Modulates Proteostasis via Binding Misfolded Proteins and Promotion of Cytoprotective Inclusion Formation.

Lee JA, Yerbury JJ, Farrawell N, Shearer RF, Constantinescu P, Hatters DM, Schroder WA, Suhrbier A, Wilson MR, Saunders DN, Ranson M.

PLoS One. 2015 Jun 17;10(6):e0130136. doi: 10.1371/journal.pone.0130136. eCollection 2015.


Multiple immune factors are involved in controlling acute and chronic chikungunya virus infection.

Poo YS, Rudd PA, Gardner J, Wilson JA, Larcher T, Colle MA, Le TT, Nakaya HI, Warrilow D, Allcock R, Bielefeldt-Ohmann H, Schroder WA, Khromykh AA, Lopez JA, Suhrbier A.

PLoS Negl Trop Dis. 2014 Dec 4;8(12):e3354. doi: 10.1371/journal.pntd.0003354. eCollection 2014 Dec.


CCR2 deficiency promotes exacerbated chronic erosive neutrophil-dominated chikungunya virus arthritis.

Poo YS, Nakaya H, Gardner J, Larcher T, Schroder WA, Le TT, Major LD, Suhrbier A.

J Virol. 2014 Jun;88(12):6862-72. doi: 10.1128/JVI.03364-13. Epub 2014 Apr 2.


Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis.

Schroder WA, Major LD, Le TT, Gardner J, Sweet MJ, Janciauskiene S, Suhrbier A.

Cancer Med. 2014 Jun;3(3):500-13. doi: 10.1002/cam4.229. Epub 2014 Mar 19.


Induction of SerpinB2 and Th1/Th2 modulation by SerpinB2 during lentiviral infections in vivo.

Major LD, Partridge TS, Gardner J, Kent SJ, de Rose R, Suhrbier A, Schroder WA.

PLoS One. 2013;8(2):e57343. doi: 10.1371/journal.pone.0057343. Epub 2013 Feb 27.


Disseminated varicella infection caused by varicella vaccine strain in a child with low invariant natural killer T cells and diminished CD1d expression.

Banovic T, Yanilla M, Simmons R, Robertson I, Schroder WA, Raffelt NC, Wilson YA, Hill GR, Hogan P, Nourse CB.

J Infect Dis. 2011 Dec 15;204(12):1893-901. doi: 10.1093/infdis/jir660. Epub 2011 Oct 31.


The role of SerpinB2 in immunity.

Schroder WA, Major L, Suhrbier A.

Crit Rev Immunol. 2011;31(1):15-30. Review.


SerpinB2 deficiency modulates Th1⁄Th2 responses after schistosome infection.

Schroder WA, Gardner J, Le TT, Duke M, Burke ML, Jones MK, McManus DP, Suhrbier A.

Parasite Immunol. 2010 Nov-Dec;32(11-12):764-8.


Human papilloma virus transformed CaSki cells constitutively express high levels of functional SerpinB2.

Major L, Schroder WA, Gardner J, Fish RJ, Suhrbier A.

Exp Cell Res. 2011 Feb 1;317(3):338-47. doi: 10.1016/j.yexcr.2010.10.016. Epub 2010 Oct 23.


Chikungunya virus arthritis in adult wild-type mice.

Gardner J, Anraku I, Le TT, Larcher T, Major L, Roques P, Schroder WA, Higgs S, Suhrbier A.

J Virol. 2010 Aug;84(16):8021-32. doi: 10.1128/JVI.02603-09. Epub 2010 Jun 2.


Melanocyte homeostasis in vivo tolerates Rb1 loss in a developmentally independent fashion.

Tonks ID, Mould AW, Schroder WA, Hacker E, Bosenberg M, Hayward NK, Walker GJ, Kay GF.

Pigment Cell Melanoma Res. 2010 Aug;23(4):564-70. doi: 10.1111/j.1755-148X.2010.00722.x. Epub 2010 May 26.


Dual loss of rb1 and Trp53 in the adrenal medulla leads to spontaneous pheochromocytoma.

Tonks ID, Mould AW, Schroder WA, Cotterill A, Hayward NK, Walker GJ, Kay GF.

Neoplasia. 2010 Mar;12(3):235-43.


A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunity.

Schroder WA, Le TT, Major L, Street S, Gardner J, Lambley E, Markey K, MacDonald KP, Fish RJ, Thomas R, Suhrbier A.

J Immunol. 2010 Mar 1;184(5):2663-70. doi: 10.4049/jimmunol.0902187. Epub 2010 Feb 3.


Immunostimulatory cancer chemotherapy using local ingenol-3-angelate and synergy with immunotherapies.

Le TT, Gardner J, Hoang-Le D, Schmidt CW, MacDonald KP, Lambley E, Schroder WA, Ogbourne SM, Suhrbier A.

Vaccine. 2009 May 18;27(23):3053-62. doi: 10.1016/j.vaccine.2009.03.025. Epub 2009 Apr 3.


Dual loss of Rb1 and Trp53 in melanocytes perturbs melanocyte homeostasis and genetic stability in vitro but does not cause melanoma or pigmentation defects in vivo.

Tonks ID, Mould A, Nurcombe V, Cool SM, Walker GJ, Hacker E, Keith P, Schroder WA, Cotterill A, Hayward NK, Kay GF.

Pigment Cell Melanoma Res. 2009 Jun;22(3):328-30. doi: 10.1111/j.1755-148X.2009.00560.x. Epub 2009 Feb 25. No abstract available.


Ticks associated with macquarie island penguins carry arboviruses from four genera.

Major L, Linn ML, Slade RW, Schroder WA, Hyatt AD, Gardner J, Cowley J, Suhrbier A.

PLoS One. 2009;4(2):e4375. doi: 10.1371/journal.pone.0004375. Epub 2009 Feb 5.


A Kunjin replicon vector encoding granulocyte macrophage colony-stimulating factor for intra-tumoral gene therapy.

Hoang-Le D, Smeenk L, Anraku I, Pijlman GP, Wang XJ, de Vrij J, Liu WJ, Le TT, Schroder WA, Khromykh AA, Suhrbier A.

Gene Ther. 2009 Feb;16(2):190-9. doi: 10.1038/gt.2008.169. Epub 2008 Dec 18.


VCAM-1 and VLA-4 modulate dendritic cell IL-12p40 production in experimental visceral leishmaniasis.

Stanley AC, Dalton JE, Rossotti SH, MacDonald KP, Zhou Y, Rivera F, Schroder WA, Maroof A, Hill GR, Kaye PM, Engwerda CR.

PLoS Pathog. 2008 Sep 19;4(9):e1000158. doi: 10.1371/journal.ppat.1000158.


Kunjin replicon-based simian immunodeficiency virus gag vaccines.

Anraku I, Mokhonov VV, Rattanasena P, Mokhonova EI, Leung J, Pijlman G, Cara A, Schroder WA, Khromykh AA, Suhrbier A.

Vaccine. 2008 Jun 19;26(26):3268-76. doi: 10.1016/j.vaccine.2008.04.001. Epub 2008 Apr 21.


Human papillomavirus E7 requires the protease calpain to degrade the retinoblastoma protein.

Darnell GA, Schroder WA, Antalis TM, Lambley E, Major L, Gardner J, Birrell G, Cid-Arregui A, Suhrbier A.

J Biol Chem. 2007 Dec 28;282(52):37492-500. Epub 2007 Oct 31.


Human Sin1 contains Ras-binding and pleckstrin homology domains and suppresses Ras signalling.

Schroder WA, Buck M, Cloonan N, Hancock JF, Suhrbier A, Sculley T, Bushell G.

Cell Signal. 2007 Jun;19(6):1279-89. Epub 2007 Jan 20.


SerpinB2 is an inducible host factor involved in enhancing HIV-1 transcription and replication.

Darnell GA, Schroder WA, Gardner J, Harrich D, Yu H, Medcalf RL, Warrilow D, Antalis TM, Sonza S, Suhrbier A.

J Biol Chem. 2006 Oct 20;281(42):31348-58. Epub 2006 Aug 21.

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