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Items: 1 to 50 of 67

1.

Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat.

Schulz TJ, Huang TL, Tran TT, Zhang H, Townsend KL, Shadrach JL, Cerletti M, McDougall LE, Giorgadze N, Tchkonia T, Schrier D, Falb D, Kirkland JL, Wagers AJ, Tseng YH.

Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):143-8. doi: 10.1073/pnas.1010929108. Epub 2010 Dec 20.

2.

Central role of the MEK/ERK MAP kinase pathway in a mouse model of rheumatoid arthritis: potential proinflammatory mechanisms.

Thiel MJ, Schaefer CJ, Lesch ME, Mobley JL, Dudley DT, Tecle H, Barrett SD, Schrier DJ, Flory CM.

Arthritis Rheum. 2007 Oct;56(10):3347-57.

3.

PD-0200347, an alpha2delta ligand of the voltage gated calcium channel, inhibits in vivo activation of the Erk1/2 pathway in osteoarthritic chondrocytes: a PKCalpha dependent effect.

Boileau C, Martel-Pelletier J, Brunet J, Schrier D, Flory C, Boily M, Pelletier JP.

Ann Rheum Dis. 2006 May;65(5):573-80. Epub 2005 Oct 25.

4.
5.

Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis.

Bove SE, Calcaterra SL, Brooker RM, Huber CM, Guzman RE, Juneau PL, Schrier DJ, Kilgore KS.

Osteoarthritis Cartilage. 2003 Nov;11(11):821-30.

6.

In vivo selective inhibition of mitogen-activated protein kinase kinase 1/2 in rabbit experimental osteoarthritis is associated with a reduction in the development of structural changes.

Pelletier JP, Fernandes JC, Brunet J, Moldovan F, Schrier D, Flory C, Martel-Pelletier J.

Arthritis Rheum. 2003 Jun;48(6):1582-93.

7.

Ribozymes as tools for therapeutic target validation in arthritis.

Jarvis TC, Bouhana KS, Lesch ME, Brown SA, Parry TJ, Schrier DJ, Hunt SW 3rd, Pavco PA, Flory CM.

J Immunol. 2000 Jul 1;165(1):493-8.

8.

Effects of the phosphodiesterase inhibitor rolipram on streptococcal cell wall-induced arthritis in rats.

Laemont KD, Schaefer CJ, Juneau PL, Schrier DJ.

Int J Immunopharmacol. 1999 Nov;21(11):711-25.

PMID:
10576617
9.

Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 2. 1,3,4- and 1,2,4-thiadiazole series.

Song Y, Connor DT, Sercel AD, Sorenson RJ, Doubleday R, Unangst PC, Roth BD, Beylin VG, Gilbertsen RB, Chan K, Schrier DJ, Guglietta A, Bornemeier DA, Dyer RD.

J Med Chem. 1999 Apr 8;42(7):1161-9.

PMID:
10197960
10.

Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.

Song Y, Connor DT, Doubleday R, Sorenson RJ, Sercel AD, Unangst PC, Roth BD, Gilbertsen RB, Chan K, Schrier DJ, Guglietta A, Bornemeier DA, Dyer RD.

J Med Chem. 1999 Apr 8;42(7):1151-60.

PMID:
10197959
11.

Effects of novel anti-inflammatory compounds on healing of acetic acid-induced gastric ulcer in rats.

Lesch CA, Gilbertsen RB, Song Y, Dyer RD, Schrier D, Kraus ER, Sanchez B, Guglietta A.

J Pharmacol Exp Ther. 1998 Oct;287(1):301-6.

PMID:
9765350
12.

Streptococcal cell wall-induced arthritis: requirements for IL-4, IL-10, IFN-gamma, and monocyte chemoattractant protein-1.

Schimmer RC, Schrier DJ, Flory CM, Laemont KD, Tung D, Metz AL, Friedl HP, Conroy MC, Warren JS, Beck B, Ward PA.

J Immunol. 1998 Feb 1;160(3):1466-71.

13.
14.

Streptococcal cell wall-induced arthritis. Requirements for neutrophils, P-selectin, intercellular adhesion molecule-1, and macrophage-inflammatory protein-2.

Schimmer RC, Schrier DJ, Flory CM, Dykens J, Tung DK, Jacobson PB, Friedl HP, Conroy MC, Schimmer BB, Ward PA.

J Immunol. 1997 Oct 15;159(8):4103-8.

PMID:
9379001
15.

Expression of lung vascular and airway ICAM-1 after exposure to bacterial lipopolysaccharide.

Beck-Schimmer B, Schimmer RC, Warner RL, Schmal H, Nordblom G, Flory CM, Lesch ME, Friedl HP, Schrier DJ, Ward PA.

Am J Respir Cell Mol Biol. 1997 Sep;17(3):344-52.

PMID:
9308921
17.

Inhibition of adhesion molecule expression by N-alkylthiopyridine-benzo[b]thiophene-2-carboxamides.

Boschelli DH, Connor DT, Lesch ME, Schrier DJ.

Bioorg Med Chem. 1996 Apr;4(4):557-62.

PMID:
8735844
18.

Streptococcal cysteine protease augments lung injury induced by products of group A streptococci.

Shanley TP, Schrier D, Kapur V, Kehoe M, Musser JM, Ward PA.

Infect Immun. 1996 Mar;64(3):870-7.

19.

Nuclease-resistant ribozymes decrease stromelysin mRNA levels in rabbit synovium following exogenous delivery to the knee joint.

Flory CM, Pavco PA, Jarvis TC, Lesch ME, Wincott FE, Beigelman L, Hunt SW 3rd, Schrier DJ.

Proc Natl Acad Sci U S A. 1996 Jan 23;93(2):754-8.

20.

High-dose 90Y Mx-diethylenetriaminepentaacetic acid (DTPA)-BrE-3 and autologous hematopoietic stem cell support (AHSCS) for the treatment of advanced breast cancer: a phase I trial.

Schrier DM, Stemmer SM, Johnson T, Kasliwal R, Lear J, Matthes S, Taffs S, Dufton C, Glenn SD, Butchko G, et al.

Cancer Res. 1995 Dec 1;55(23 Suppl):5921s-5924s.

21.

Anti-inflammatory properties of Gö 6850: a selective inhibitor of protein kinase C.

Jacobson PB, Kuchera SL, Metz A, Schächtele C, Imre K, Schrier DJ.

J Pharmacol Exp Ther. 1995 Nov;275(2):995-1002.

PMID:
7473193
22.

Cytoprotective effects of CI-959 in the rat gastric mucosa: modulation of leukocyte adhesion.

Low J, Grabow D, Sommers C, Wallace J, Lesch M, Finkel M, Schrier D, Metz A, Conroy MC.

Gastroenterology. 1995 Oct;109(4):1224-33.

PMID:
7557089
23.

3-Alkoxybenzo[b]thiophene-2-carboxamides as inhibitors of neutrophil-endothelial cell adhesion.

Boschelli DH, Kramer JB, Connor DT, Lesch ME, Schrier DJ, Ferin MA, Wright CD.

J Med Chem. 1994 Mar 18;37(6):717-8. No abstract available.

PMID:
8145218
24.
25.
26.

Regulation of CD11b/CD18 expression in human neutrophils by phospholipase A2.

Jacobson PB, Schrier DJ.

J Immunol. 1993 Nov 15;151(10):5639-52.

PMID:
8228253
27.

1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities.

Boschelli DH, Connor DT, Bornemeier DA, Dyer RD, Kennedy JA, Kuipers PJ, Okonkwo GC, Schrier DJ, Wright CD.

J Med Chem. 1993 Jun 25;36(13):1802-10.

PMID:
8515419
28.
30.

Novel 1,2,4-oxadiazoles and 1,2,4-thiadiazoles as dual 5-lipoxygenase and cyclooxygenase inhibitors.

Unangst PC, Shrum GP, Connor DT, Dyer RD, Schrier DJ.

J Med Chem. 1992 Oct 2;35(20):3691-8.

PMID:
1433181
31.

The biochemistry and pharmacology of PD 116124 (8-amino-2'-nordeoxyguanosine), an inhibitor of purine nucleoside phosphorylase (PNP).

Dong MK, Scott ME, Schrier DJ, Suto MJ, Sircar JC, Black A, Chang T, Gilbertsen RB.

J Pharmacol Exp Ther. 1992 Jan;260(1):319-26.

PMID:
1530976
33.

Styrylpyrazoles, styrylisoxazoles, and styrylisothiazoles. Novel 5-lipoxygenase and cyclooxygenase inhibitors.

Flynn DL, Belliotti TR, Boctor AM, Connor DT, Kostlan CR, Nies DE, Ortwine DF, Schrier DJ, Sircar JC.

J Med Chem. 1991 Feb;34(2):518-25.

PMID:
1847426
34.

The antiinflammatory effects of adenosine receptor agonists on the carrageenan-induced pleural inflammatory response in rats.

Schrier DJ, Lesch ME, Wright CD, Gilbertsen RB.

J Immunol. 1990 Sep 15;145(6):1874-9.

PMID:
2167912
35.

Nonsteroidal antiinflammatory drug hydroxamic acids. Dual inhibitors of both cyclooxygenase and 5-lipoxygenase.

Flynn DL, Capiris T, Cetenko WJ, Connor DT, Dyer RD, Kostlan CR, Nies DE, Schrier DJ, Sircar JC.

J Med Chem. 1990 Aug;33(8):2070-2. No abstract available.

PMID:
2115586
36.

Formula for calculating partial cross sections for nuclear reactions of nuclei with E >~ 200 MeV/nucleon in hydrogen targets.

Webber WR, Kish JC, Schrier DA.

Phys Rev C Nucl Phys. 1990 Feb;41(2):566-571. No abstract available.

PMID:
9966389
37.

Individual isotopic fragmentation cross sections of relativistic nuclei in hydrogen, helium, and carbon targets.

Webber WR, Kish JC, Schrier DA.

Phys Rev C Nucl Phys. 1990 Feb;41(2):547-565. No abstract available.

PMID:
9966388
38.

Individual charge changing fragmentation cross sections of relativistic nuclei in hydrogen, helium, and carbon targets.

Webber WR, Kish JC, Schrier DA.

Phys Rev C Nucl Phys. 1990 Feb;41(2):533-546. No abstract available.

PMID:
9966387
39.

Total charge and mass changing cross sections of relativistic nuclei in hydrogen, helium, and carbon targets.

Webber WR, Kish JC, Schrier DA.

Phys Rev C Nucl Phys. 1990 Feb;41(2):520-532. No abstract available.

PMID:
9966386
40.

The in vivo antiinflammatory effects of (E)-2,6-bis(1,1-dimethyl-ethyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethenyl ] phenol (PD 127443) a novel dual inhibitor of 5-lipoxygenase and cyclooxygenase.

Schrier DJ, Adamchak MA, Boctor AM, Kostlan CR, Flynn DL, Jordan JH Jr, Lesch ME, Okonkwo GC.

Agents Actions. 1989 Jun;27(3-4):391-4. No abstract available.

PMID:
2552768
41.

The phosphatidylinositol response of chondrocytes in culture.

Baragi VM, Dudley DT, Schrier DJ.

Agents Actions. 1989 Jun;27(3-4):428-30.

PMID:
2508445
42.

Measurement of 12C, 16O, and 56Fe charge changing cross sections in helium at high energy, comparison with cross sections in hydrogen, and application to cosmic-ray propagation.

Ferrando P, Webber WR, Goret P, Kish JC, Schrier DA, Soutoul A, Testard O.

Phys Rev C Nucl Phys. 1988 Apr;37(4):1490-1501. No abstract available.

PMID:
9954603
43.

Preliminary report on 8-amino-9-(2-thienylmethyl)guanine (PD 119,229), a novel and potent purine nucleoside phosphorylase inhibitor.

Gilbertsen RB, Scott ME, Dong MK, Kossarek LM, Bennett MK, Schrier DJ, Sircar JC.

Agents Actions. 1987 Aug;21(3-4):272-4.

PMID:
3120507
44.

The topical anti-inflammatory effects of a topical preparation of meclofenamic acid on carrageenan-induced footpad swelling in mice.

Schrier DJ, Moniot S, Gluckman MI, Gilbertsen RB.

J Pharm Pharmacol. 1987 Jan;39(1):57-9.

PMID:
2880988
45.

The effects of adenosine agonists on human neutrophil function.

Schrier DJ, Imre KM.

J Immunol. 1986 Nov 15;137(10):3284-9.

PMID:
3021850
46.

Phenelzine-induced hypomania: effect of verapamil.

Dubovsky SL, Franks RD, Schrier D.

Biol Psychiatry. 1985 Sep;20(9):1009-14. No abstract available.

PMID:
4027309
47.
48.

The role of neutrophils in type II collagen-induced arthritis in rats.

Schrier D, Gilbertsen RB, Lesch M, Fantone J.

Am J Pathol. 1984 Oct;117(1):26-9.

50.

Effects of antiarthritic compounds on type II collagen-induced arthritis in rats.

Probert AW Jr, Schrier DJ, Gilbertsen RB.

Arch Int Pharmacodyn Ther. 1984 May;269(1):167-76.

PMID:
6466005

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