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Items: 1 to 50 of 80

1.

The CHD6 chromatin remodeler is an oxidative DNA damage response factor.

Moore S, Berger ND, Luijsterburg MS, Piett CG, Stanley FKT, Schräder CU, Fang S, Chan JA, Schriemer DC, Nagel ZD, van Attikum H, Goodarzi AA.

Nat Commun. 2019 Jan 16;10(1):241. doi: 10.1038/s41467-018-08111-y.

2.

Photo-Cross-Linking Mass Spectrometry and Integrative Modeling Enables Rapid Screening of Antigen Interactions Involving Bacterial Transferrin Receptors.

Ziemianowicz DS, Ng D, Schryvers AB, Schriemer DC.

J Proteome Res. 2019 Mar 1;18(3):934-946. doi: 10.1021/acs.jproteome.8b00629. Epub 2019 Jan 11.

PMID:
30582701
3.

Lysine Propionylation To Boost Sequence Coverage and Enable a "Silent SILAC" Strategy for Relative Protein Quantification.

Schräder CU, Moore S, Goodarzi AA, Schriemer DC.

Anal Chem. 2018 Aug 7;90(15):9077-9084. doi: 10.1021/acs.analchem.8b01403. Epub 2018 Jul 20.

PMID:
29975514
4.

Simultaneous Proteoform Analysis of Histones H3 and H4 with a Simplified Middle-Down Proteomics Method.

Schräder CU, Ziemianowicz DS, Merx K, Schriemer DC.

Anal Chem. 2018 Mar 6;90(5):3083-3090. doi: 10.1021/acs.analchem.7b03948. Epub 2018 Feb 15.

PMID:
29405698
5.

Amino Acid Insertion Frequencies Arising from Photoproducts Generated Using Aliphatic Diazirines.

Ziemianowicz DS, Bomgarden R, Etienne C, Schriemer DC.

J Am Soc Mass Spectrom. 2017 Oct;28(10):2011-2021. doi: 10.1007/s13361-017-1730-z. Epub 2017 Aug 10.

PMID:
28799075
6.

Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complex.

Aceytuno RD, Piett CG, Havali-Shahriari Z, Edwards RA, Rey M, Ye R, Javed F, Fang S, Mani R, Weinfeld M, Hammel M, Tainer JA, Schriemer DC, Lees-Miller SP, Glover JNM.

Nucleic Acids Res. 2017 Jun 2;45(10):6238-6251. doi: 10.1093/nar/gkx275.

7.

Neprosin, a Selective Prolyl Endoprotease for Bottom-up Proteomics and Histone Mapping.

Schräder CU, Lee L, Rey M, Sarpe V, Man P, Sharma S, Zabrouskov V, Larsen B, Schriemer DC.

Mol Cell Proteomics. 2017 Jun;16(6):1162-1171. doi: 10.1074/mcp.M116.066803. Epub 2017 Apr 12.

8.

Lactoferrin binding protein B - a bi-functional bacterial receptor protein.

Ostan NK, Yu RH, Ng D, Lai CC, Pogoutse AK, Sarpe V, Hepburn M, Sheff J, Raval S, Schriemer DC, Moraes TF, Schryvers AB.

PLoS Pathog. 2017 Mar 3;13(3):e1006244. doi: 10.1371/journal.ppat.1006244. eCollection 2017 Mar.

9.

Nanospray HX-MS configuration for structural interrogation of large protein systems.

Sheff JG, Hepburn M, Yu Y, Lees-Miller SP, Schriemer DC.

Analyst. 2017 Mar 13;142(6):904-910. doi: 10.1039/c6an02707e.

PMID:
28154854
10.

Novel Allosteric Pathway of Eg5 Regulation Identified through Multivariate Statistical Analysis of Hydrogen-Exchange Mass Spectrometry (HX-MS) Ligand Screening Data.

Sheff JG, Farshidfar F, Bathe OF, Kopciuk K, Gentile F, Tuszynski J, Barakat K, Schriemer DC.

Mol Cell Proteomics. 2017 Mar;16(3):428-437. doi: 10.1074/mcp.M116.064246. Epub 2017 Jan 5.

11.

Supporting metabolomics with adaptable software: design architectures for the end-user.

Sarpe V, Schriemer DC.

Curr Opin Biotechnol. 2017 Feb;43:110-117. doi: 10.1016/j.copbio.2016.11.001. Epub 2016 Nov 18. Review.

PMID:
27870998
12.

Addressing proteolytic efficiency in enzymatic degradation therapy for celiac disease.

Rey M, Yang M, Lee L, Zhang Y, Sheff JG, Sensen CW, Mrazek H, Halada P, Man P, McCarville JL, Verdu EF, Schriemer DC.

Sci Rep. 2016 Aug 2;6:30980. doi: 10.1038/srep30980.

13.

Carnivorous Nutrition in Pitcher Plants (Nepenthes spp.) via an Unusual Complement of Endogenous Enzymes.

Lee L, Zhang Y, Ozar B, Sensen CW, Schriemer DC.

J Proteome Res. 2016 Sep 2;15(9):3108-17. doi: 10.1021/acs.jproteome.6b00224. Epub 2016 Aug 1.

PMID:
27436081
14.

High Sensitivity Crosslink Detection Coupled With Integrative Structure Modeling in the Mass Spec Studio.

Sarpe V, Rafiei A, Hepburn M, Ostan N, Schryvers AB, Schriemer DC.

Mol Cell Proteomics. 2016 Sep;15(9):3071-80. doi: 10.1074/mcp.O116.058685. Epub 2016 Jul 13.

15.

A robust capillary liquid chromatography/tandem mass spectrometry method for quantitation of neuromodulatory endocannabinoids.

Qi M, Morena M, Vecchiarelli HA, Hill MN, Schriemer DC.

Rapid Commun Mass Spectrom. 2015 Oct 30;29(20):1889-97. doi: 10.1002/rcm.7277.

PMID:
26411510
16.

A hypothesis-directed approach to the targeted development of a multiplexed proteomic biomarker assay for cancer.

Mackay EM, Koppel J, Das P, Woo J, Schriemer DC, Bathe OF.

Cancer Inform. 2015 May 17;14:65-70. doi: 10.4137/CIN.S24388. eCollection 2015.

17.

HX-MS2 for high performance conformational analysis of complex protein states.

Burns KM, Sarpe V, Wagenbach M, Wordeman L, Schriemer DC.

Protein Sci. 2015 Aug;24(8):1313-24. doi: 10.1002/pro.2707. Epub 2015 May 29. Erratum in: Protein Sci. 2016 Jan;25(1):302-3.

18.

Recombinant Nepenthesin II for Hydrogen/Deuterium Exchange Mass Spectrometry.

Yang M, Hoeppner M, Rey M, Kadek A, Man P, Schriemer DC.

Anal Chem. 2015 Jul 7;87(13):6681-7. doi: 10.1021/acs.analchem.5b00831. Epub 2015 Jun 8.

PMID:
25993527
19.

Toward standardizing deuterium content reporting in hydrogen exchange-MS.

Sheff JG, Schriemer DC.

Anal Chem. 2014 Dec 16;86(24):11962-5. doi: 10.1021/ac5034424. Epub 2014 Dec 5.

PMID:
25427063
20.

Mass spec studio for integrative structural biology.

Rey M, Sarpe V, Burns KM, Buse J, Baker CA, van Dijk M, Wordeman L, Bonvin AM, Schriemer DC.

Structure. 2014 Oct 7;22(10):1538-48. doi: 10.1016/j.str.2014.08.013. Epub 2014 Sep 18.

21.

Nucleotide exchange in dimeric MCAK induces longitudinal and lateral stress at microtubule ends to support depolymerization.

Burns KM, Wagenbach M, Wordeman L, Schriemer DC.

Structure. 2014 Aug 5;22(8):1173-1183. doi: 10.1016/j.str.2014.06.010. Epub 2014 Jul 24.

22.

Tracking allosteric propagation with HX-MS.

Braun AP, Schriemer DC.

Structure. 2014 Apr 8;22(4):512-4. doi: 10.1016/j.str.2014.03.005.

23.

Aspartic protease nepenthesin-1 as a tool for digestion in hydrogen/deuterium exchange mass spectrometry.

Kadek A, Mrazek H, Halada P, Rey M, Schriemer DC, Man P.

Anal Chem. 2014 May 6;86(9):4287-94. doi: 10.1021/ac404076j. Epub 2014 Apr 8.

PMID:
24661217
24.

Expression and characterization of plant aspartic protease nepenthesin-1 from Nepenthes gracilis.

Kadek A, Tretyachenko V, Mrazek H, Ivanova L, Halada P, Rey M, Schriemer DC, Man P.

Protein Expr Purif. 2014 Mar;95:121-8. doi: 10.1016/j.pep.2013.12.005. Epub 2013 Dec 21.

PMID:
24365662
25.

Morphine biosynthesis in opium poppy involves two cell types: sieve elements and laticifers.

Onoyovwe A, Hagel JM, Chen X, Khan MF, Schriemer DC, Facchini PJ.

Plant Cell. 2013 Oct;25(10):4110-22. doi: 10.1105/tpc.113.115113. Epub 2013 Oct 8.

26.

Taccalonolide binding to tubulin imparts microtubule stability and potent in vivo activity.

Risinger AL, Li J, Bennett MJ, Rohena CC, Peng J, Schriemer DC, Mooberry SL.

Cancer Res. 2013 Nov 15;73(22):6780-92. doi: 10.1158/0008-5472.CAN-13-1346. Epub 2013 Sep 18.

27.

Peptide-column interactions and their influence on back exchange rates in hydrogen/deuterium exchange-MS.

Sheff JG, Rey M, Schriemer DC.

J Am Soc Mass Spectrom. 2013 Jul;24(7):1006-15. doi: 10.1007/s13361-013-0639-4. Epub 2013 May 7.

PMID:
23649779
28.

Structural changes in the C-terminal regulatory region of the Na⁺/H⁺ exchanger mediate phosphorylation induced regulation.

Li X, Khan MF, Schriemer DC, Fliegel L.

J Mol Cell Cardiol. 2013 Aug;61:153-63. doi: 10.1016/j.yjmcc.2013.04.007. Epub 2013 Apr 17.

PMID:
23602949
29.

The membrane-binding domain of an amphitropic enzyme suppresses catalysis by contact with an amphipathic helix flanking its active site.

Huang HK, Taneva SG, Lee J, Silva LP, Schriemer DC, Cornell RB.

J Mol Biol. 2013 May 13;425(9):1546-64. doi: 10.1016/j.jmb.2012.12.003. Epub 2012 Dec 10. Erratum in: J Mol Biol. 2013 Sep 23;425(18):3576.

PMID:
23238251
30.

Nepenthesin from monkey cups for hydrogen/deuterium exchange mass spectrometry.

Rey M, Yang M, Burns KM, Yu Y, Lees-Miller SP, Schriemer DC.

Mol Cell Proteomics. 2013 Feb;12(2):464-72. doi: 10.1074/mcp.M112.025221. Epub 2012 Nov 29.

31.

Platform dependencies in bottom-up hydrogen/deuterium exchange mass spectrometry.

Burns KM, Rey M, Baker CA, Schriemer DC.

Mol Cell Proteomics. 2013 Feb;12(2):539-48. doi: 10.1074/mcp.M112.023770. Epub 2012 Nov 28.

32.

Characterization of staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1.

Milev MP, Ravichandran M, Khan MF, Schriemer DC, Mouland AJ.

Front Microbiol. 2012 Oct 25;3:367. doi: 10.3389/fmicb.2012.00367. eCollection 2012.

33.

Low-dose laulimalide represents a novel molecular probe for investigating microtubule organization.

Bennett MJ, Chan GK, Rattner JB, Schriemer DC.

Cell Cycle. 2012 Aug 15;11(16):3045-54. doi: 10.4161/cc.21411. Epub 2012 Aug 8.

34.

Assembly of Ebola virus matrix protein VP40 is regulated by latch-like properties of N and C terminal tails.

Silva LP, Vanzile M, Bavari S, Aman JM, Schriemer DC.

PLoS One. 2012;7(7):e39978. doi: 10.1371/journal.pone.0039978. Epub 2012 Jul 5.

35.

High-resolution mapping of carbene-based protein footprints.

Jumper CC, Bomgarden R, Rogers J, Etienne C, Schriemer DC.

Anal Chem. 2012 May 15;84(10):4411-8. doi: 10.1021/ac300120z. Epub 2012 Apr 25.

PMID:
22480364
36.

Probing protein interactions with hydrogen/deuterium exchange and mass spectrometry-a review.

Percy AJ, Rey M, Burns KM, Schriemer DC.

Anal Chim Acta. 2012 Apr 6;721:7-21. doi: 10.1016/j.aca.2012.01.037. Epub 2012 Jan 31. Review.

PMID:
22405295
37.

Insight into the redox regulation of the phosphoglucan phosphatase SEX4 involved in starch degradation.

Silver DM, Silva LP, Issakidis-Bourguet E, Glaring MA, Schriemer DC, Moorhead GB.

FEBS J. 2013 Jan;280(2):538-48. doi: 10.1111/j.1742-4658.2012.08546.x. Epub 2012 Mar 21.

38.

Steric and allosteric factors prevent simultaneous binding of transferrin-binding proteins A and B to transferrin.

Silva LP, Yu RH, Calmettes C, Yang X, Moraes TF, Schriemer DC, Schryvers AB.

Biochem J. 2012 Jun 1;444(2):189-97. doi: 10.1042/BJ20112133.

PMID:
22369045
39.

Hydrogen-deuterium exchange coupled to mass spectrometry to investigate ligand-receptor interactions.

Ling JM, Silva L, Schriemer DC, Schryvers AB.

Methods Mol Biol. 2012;799:237-52. doi: 10.1007/978-1-61779-346-2_15.

PMID:
21993650
40.

Mutations in the β-tubulin binding site for peloruside A confer resistance by targeting a cleft significant in side chain binding.

Begaye A, Trostel S, Zhao Z, Taylor RE, Schriemer DC, Sackett DL.

Cell Cycle. 2011 Oct 1;10(19):3387-96. doi: 10.4161/cc.10.19.17706. Epub 2011 Oct 1.

41.

XRCC4 protein interactions with XRCC4-like factor (XLF) create an extended grooved scaffold for DNA ligation and double strand break repair.

Hammel M, Rey M, Yu Y, Mani RS, Classen S, Liu M, Pique ME, Fang S, Mahaney BL, Weinfeld M, Schriemer DC, Lees-Miller SP, Tainer JA.

J Biol Chem. 2011 Sep 16;286(37):32638-50. doi: 10.1074/jbc.M111.272641. Epub 2011 Jul 20.

42.

Conserved interaction between transferrin and transferrin-binding proteins from porcine pathogens.

Silva LP, Yu R, Calmettes C, Yang X, Moraes TF, Schryvers AB, Schriemer DC.

J Biol Chem. 2011 Jun 17;286(24):21353-60. doi: 10.1074/jbc.M111.226449. Epub 2011 Apr 12.

43.

Proteome of the Caenorhabditis elegans oocyte.

Chik JK, Schriemer DC, Childs SJ, McGhee JD.

J Proteome Res. 2011 May 6;10(5):2300-5. doi: 10.1021/pr101124f. Epub 2011 Apr 15.

PMID:
21452892
44.

Mass spectrometry of laser-initiated carbene reactions for protein topographic analysis.

Jumper CC, Schriemer DC.

Anal Chem. 2011 Apr 15;83(8):2913-20. doi: 10.1021/ac102655f. Epub 2011 Mar 22.

PMID:
21425771
45.

Proteomics by mass spectrometry--go big or go home?

Khan MF, Bennett MJ, Jumper CC, Percy AJ, Silva LP, Schriemer DC.

J Pharm Biomed Anal. 2011 Jun 25;55(4):832-41. doi: 10.1016/j.jpba.2011.02.012. Epub 2011 Feb 17. Review.

PMID:
21382686
46.

Structural variations within the transferrin binding site on transferrin-binding protein B, TbpB.

Calmettes C, Yu RH, Silva LP, Curran D, Schriemer DC, Schryvers AB, Moraes TF.

J Biol Chem. 2011 Apr 8;286(14):12683-92. doi: 10.1074/jbc.M110.206102. Epub 2011 Feb 5.

47.

Integration of deep transcriptome and proteome analyses reveals the components of alkaloid metabolism in opium poppy cell cultures.

Desgagné-Penix I, Khan MF, Schriemer DC, Cram D, Nowak J, Facchini PJ.

BMC Plant Biol. 2010 Nov 18;10:252. doi: 10.1186/1471-2229-10-252.

48.

Discovery and characterization of the laulimalide-microtubule binding mode by mass shift perturbation mapping.

Bennett MJ, Barakat K, Huzil JT, Tuszynski J, Schriemer DC.

Chem Biol. 2010 Jul 30;17(7):725-34. doi: 10.1016/j.chembiol.2010.05.019.

49.

Delineating the regions of human transferrin involved in interactions with transferrin binding protein B from Neisseria meningitidis.

Ling JM, Shima CH, Schriemer DC, Schryvers AB.

Mol Microbiol. 2010 Sep;77(5):1301-14. doi: 10.1111/j.1365-2958.2010.07289.x.

50.

Rheostatic control of tryptic digestion in a microscale fluidic system.

Percy AJ, Schriemer DC.

Anal Chim Acta. 2010 Jan 4;657(1):53-9. doi: 10.1016/j.aca.2009.10.019. Epub 2009 Oct 26.

PMID:
19951757

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