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Items: 1 to 50 of 64

1.

GIRK1 triggers multiple cancer-related pathways in the benign mammary epithelial cell line MCF10A.

Schratter G, Scheruebel S, Langthaler S, Ester K, Pelzmann B, Ghaffari-Tabrizi-Wizsy N, Rezania S, Gorischek A, Platzer D, Zorn-Pauly K, Ahammer H, Prokesch A, Stanzer S, Devaney TTJ, Schmidt K, Jahn SW, Prassl R, Bauernhofer T, Schreibmayer W.

Sci Rep. 2019 Dec 17;9(1):19277. doi: 10.1038/s41598-019-55683-w.

2.

A single point mutation in the TRPC3 lipid-recognition window generates supersensitivity to benzimidazole channel activators.

Svobodova B, Lichtenegger M, Platzer D, Di Giuro CML, de la Cruz GG, Glasnov T, Schreibmayer W, Groschner K.

Cell Calcium. 2019 May;79:27-34. doi: 10.1016/j.ceca.2019.02.007. Epub 2019 Feb 16.

3.

An optically controlled probe identifies lipid-gating fenestrations within the TRPC3 channel.

Lichtenegger M, Tiapko O, Svobodova B, Stockner T, Glasnov TN, Schreibmayer W, Platzer D, de la Cruz GG, Krenn S, Schober R, Shrestha N, Schindl R, Romanin C, Groschner K.

Nat Chem Biol. 2018 Apr;14(4):396-404. doi: 10.1038/s41589-018-0015-6. Epub 2018 Mar 19.

4.

KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients.

Kammerer S, Sokolowski A, Hackl H, Platzer D, Jahn SW, El-Heliebi A, Schwarzenbacher D, Stiegelbauer V, Pichler M, Rezania S, Fiegl H, Peintinger F, Regitnig P, Hoefler G, Schreibmayer W, Bauernhofer T.

Oncotarget. 2016 Dec 20;7(51):84705-84717. doi: 10.18632/oncotarget.13224.

5.

Critical evaluation of KCNJ3 gene product detection in human breast cancer: mRNA in situ hybridisation is superior to immunohistochemistry.

Kammerer S, Jahn SW, Winter E, Eidenhammer S, Rezania S, Regitnig P, Pichler M, Schreibmayer W, Bauernhofer T.

J Clin Pathol. 2016 Dec;69(12):1116-1121. doi: 10.1136/jclinpath-2016-203798. Epub 2016 Oct 3.

6.

Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner.

Rezania S, Kammerer S, Li C, Steinecker-Frohnwieser B, Gorischek A, DeVaney TT, Verheyen S, Passegger CA, Tabrizi-Wizsy NG, Hackl H, Platzer D, Zarnani AH, Malle E, Jahn SW, Bauernhofer T, Schreibmayer W.

BMC Cancer. 2016 Aug 12;16:628. doi: 10.1186/s12885-016-2664-8.

7.

Influence of Lentiviral β-Synuclein Overexpression in the Hippocampus of a Transgenic Mouse Model of Alzheimer's Disease on Amyloid Precursor Protein Metabolism and Pathology.

Krassnig S, Schweinzer C, Taub N, Havas D, Auer E, Flunkert S, Schreibmayer W, Hutter-Paier B, Windisch M.

Neurodegener Dis. 2015;15(4):243-57. doi: 10.1159/000430952. Epub 2015 Jun 25.

PMID:
26111745
8.

Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line.

Li C, Rezania S, Kammerer S, Sokolowski A, Devaney T, Gorischek A, Jahn S, Hackl H, Groschner K, Windpassinger C, Malle E, Bauernhofer T, Schreibmayer W.

Sci Rep. 2015 Feb 10;5:8364. doi: 10.1038/srep08364.

9.

Single-channel properties of α3β4, α3β4α5 and α3β4β2 nicotinic acetylcholine receptors in mice lacking specific nicotinic acetylcholine receptor subunits.

Ciuraszkiewicz A, Schreibmayer W, Platzer D, Orr-Urtreger A, Scholze P, Huck S.

J Physiol. 2013 Jul 1;591(13):3271-88. doi: 10.1113/jphysiol.2012.246595. Epub 2013 Apr 22.

10.

Molecular basis of the facilitation of the heterooligomeric GIRK1/GIRK4 complex by cAMP dependent protein kinase.

Treiber F, Rosker C, Keren-Raifman T, Steinecker B, Gorischek A, Dascal N, Schreibmayer W.

Biochim Biophys Acta. 2013 Apr;1828(4):1214-21. doi: 10.1016/j.bbamem.2012.12.016. Epub 2013 Jan 7.

11.

Four and a half LIM protein 1C (FHL1C): a binding partner for voltage-gated potassium channel K(v1.5).

Poparic I, Schreibmayer W, Schoser B, Desoye G, Gorischek A, Miedl H, Hochmeister S, Binder J, Quasthoff S, Wagner K, Windpassinger C, Malle E.

PLoS One. 2011;6(10):e26524. doi: 10.1371/journal.pone.0026524. Epub 2011 Oct 28.

12.

Cloning and characterisation of GIRK1 variants resulting from alternative RNA editing of the KCNJ3 gene transcript in a human breast cancer cell line.

Wagner V, Stadelmeyer E, Riederer M, Regitnig P, Gorischek A, Devaney T, Schmidt K, Tritthart HA, Hirschberg K, Bauernhofer T, Schreibmayer W.

J Cell Biochem. 2010 Jun 1;110(3):598-608. doi: 10.1002/jcb.22564.

PMID:
20512921
13.

Identification of the structural determinant responsible for the phosphorylation of G-protein activated potassium channel 1 by cAMP-dependent protein kinase.

Müllner C, Steinecker B, Gorischek A, Schreibmayer W.

FEBS J. 2009 Nov;276(21):6218-26. doi: 10.1111/j.1742-4658.2009.07325.x. Epub 2009 Sep 17.

14.

Emerging role(s) of G-protein alpha-subunits in the gating of GIRKs.

Schreibmayer W.

J Physiol. 2009 Sep 1;587(Pt 17):4125-6. doi: 10.1113/jphysiol.2009.179234. No abstract available.

15.

Tolperisone: a typical representative of a class of centrally acting muscle relaxants with less sedative side effects.

Quasthoff S, Möckel C, Zieglgänsberger W, Schreibmayer W.

CNS Neurosci Ther. 2008 Summer;14(2):107-19. doi: 10.1111/j.1527-3458.2008.00044.x. Review.

16.

The GIRK1 brain variant GIRK1d and its functional impact on heteromultimeric GIRK channels.

Steinecker B, Rosker C, Schreibmayer W.

J Recept Signal Transduct Res. 2007;27(5-6):369-82.

PMID:
18097938
17.

Subunit stoichiometry of heterologously expressed G-protein activated inwardly rectifying potassium channels analysed by fluorescence intensity ratio measurement.

Grasser E, Steinecker B, Ahammer H, Schreibmayer W.

Pflugers Arch. 2008 Mar;455(6):1017-24. Epub 2007 Oct 17.

PMID:
17940795
18.

The TTX metabolite 4,9-anhydro-TTX is a highly specific blocker of the Na(v1.6) voltage-dependent sodium channel.

Rosker C, Lohberger B, Hofer D, Steinecker B, Quasthoff S, Schreibmayer W.

Am J Physiol Cell Physiol. 2007 Aug;293(2):C783-9. Epub 2007 May 23.

19.

A comparative study of the action of tolperisone on seven different voltage dependent sodium channel isoforms.

Hofer D, Lohberger B, Steinecker B, Schmidt K, Quasthoff S, Schreibmayer W.

Eur J Pharmacol. 2006 May 24;538(1-3):5-14. Epub 2006 Mar 21.

PMID:
16650844
20.

The sensitivity of G protein-activated K+ channels toward halothane is essentially determined by the C terminus.

Milovic S, Steinecker-Frohnwieser B, Schreibmayer W, Weigl LG.

J Biol Chem. 2004 Aug 13;279(33):34240-9. Epub 2004 Jun 2.

21.

No blocking effects of the pentapeptide QYNAD on Na+ channel subtypes expressed in Xenopus oocytes or action potential conduction in isolated rat sural nerve.

Quasthoff S, Pojer C, Mori A, Hofer D, Liebmann P, Kieseier BC, Schreibmayer W.

Neurosci Lett. 2003 Dec 4;352(2):93-6.

PMID:
14625031
22.

Mapping the Gbetagamma-binding sites in GIRK1 and GIRK2 subunits of the G protein-activated K+ channel.

Ivanina T, Rishal I, Varon D, Mullner C, Frohnwieser-Steinecke B, Schreibmayer W, Dessauer CW, Dascal N.

J Biol Chem. 2003 Aug 1;278(31):29174-83. Epub 2003 May 12.

23.

Single channel analysis of the regulation of GIRK1/GIRK4 channels by protein phosphorylation.

Müllner C, Yakubovich D, Dessauer CW, Platzer D, Schreibmayer W.

Biophys J. 2003 Feb;84(2 Pt 1):1399-409.

24.

G protein-gated inwardly rectifying potassium channels are targets for volatile anesthetics.

Weigl LG, Schreibmayer W.

Mol Pharmacol. 2001 Aug;60(2):282-9.

PMID:
11455015
25.

S-nitrosation controls gating and conductance of the alpha 1 subunit of class C L-type Ca(2+) channels.

Poteser M, Romanin C, Schreibmayer W, Mayer B, Groschner K.

J Biol Chem. 2001 May 4;276(18):14797-803. Epub 2001 Feb 7.

26.

IK.ACh activation by arachidonic acid occurs via a G-protein-independent pathway mediated by the GIRK1 subunit.

Lohberger B, Groschner K, Tritthart H, Schreibmayer W.

Pflugers Arch. 2000 Dec;441(2-3):251-6.

PMID:
11211110
27.

Heterologous facilitation of G protein-activated K(+) channels by beta-adrenergic stimulation via cAMP-dependent protein kinase.

Müllner C, Vorobiov D, Bera AK, Uezono Y, Yakubovich D, Frohnwieser-Steinecker B, Dascal N, Schreibmayer W.

J Gen Physiol. 2000 May;115(5):547-58.

28.

Isoform diversity and modulation of sodium channels by protein kinases.

Schreibmayer W.

Cell Physiol Biochem. 1999;9(4-5):187-200. Review.

PMID:
10575197
29.

The cardiac acetylcholine-activated, inwardly rectifying K+-channel subunit GIRK1 gives rise to an inward current induced by free oxygen radicals.

Jeglitsch G, Ramos P, Encabo A, Tritthart HA, Esterbauer H, Groschner K, Schreibmayer W.

Free Radic Biol Med. 1999 Feb;26(3-4):253-9.

PMID:
9895214
30.

Trp proteins form store-operated cation channels in human vascular endothelial cells.

Groschner K, Hingel S, Lintschinger B, Balzer M, Romanin C, Zhu X, Schreibmayer W.

FEBS Lett. 1998 Oct 16;437(1-2):101-6. Erratum in: FEBS Lett 1999 Jan 8;442(1):122.

31.

Ion permeation through a G-protein activated (GIRK1/GIRK5) inwardly rectifying potassium channel.

Luchian T, Schreibmayer W.

Biochim Biophys Acta. 1998 Jan 19;1368(2):167-70.

32.

A C-terminal peptide of the GIRK1 subunit directly blocks the G protein-activated K+ channel (GIRK) expressed in Xenopus oocytes.

Luchian T, Dascal N, Dessauer C, Platzer D, Davidson N, Lester HA, Schreibmayer W.

J Physiol. 1997 Nov 15;505 ( Pt 1):13-22.

33.
34.

Inhibition of an inwardly rectifying K+ channel by G-protein alpha-subunits.

Schreibmayer W, Dessauer CW, Vorobiov D, Gilman AG, Lester HA, Davidson N, Dascal N.

Nature. 1996 Apr 18;380(6575):624-7.

PMID:
8602262
35.

Serotonin and protein kinase C modulation of a rat brain inwardly rectifying K+ channel expressed in xenopus oocytes.

DiMagno L, Dascal N, Davidson N, Lester HA, Schreibmayer W.

Pflugers Arch. 1996 Jan;431(3):335-40.

PMID:
8584426
37.

Distribution and localization of a G protein-coupled inwardly rectifying K+ channel in the rat.

Karschin C, Schreibmayer W, Dascal N, Lester H, Davidson N, Karschin A.

FEBS Lett. 1994 Jul 11;348(2):139-44.

38.

Voltage clamping of Xenopus laevis oocytes utilizing agarose-cushion electrodes.

Schreibmayer W, Lester HA, Dascal N.

Pflugers Arch. 1994 Mar;426(5):453-8.

PMID:
7517034
39.

Mechanism of modulation of single sodium channels from skeletal muscle by the beta 1-subunit from rat brain.

Schreibmayer W, Wallner M, Lotan I.

Pflugers Arch. 1994 Feb;426(3-4):360-2.

PMID:
8183650
40.

Beta-adrenergic modulation of currents produced by rat cardiac Na+ channels expressed in Xenopus laevis oocytes.

Schreibmayer W, Frohnwieser B, Dascal N, Platzer D, Spreitzer B, Zechner R, Kallen RG, Lester HA.

Receptors Channels. 1994;2(4):339-50.

PMID:
7536612
41.

Atrial G protein-activated K+ channel: expression cloning and molecular properties.

Dascal N, Schreibmayer W, Lim NF, Wang W, Chavkin C, DiMagno L, Labarca C, Kieffer BL, Gaveriaux-Ruff C, Trollinger D, et al.

Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):10235-9.

42.

Expression of an atrial G-protein-activated potassium channel in Xenopus oocytes.

Dascal N, Lim NF, Schreibmayer W, Wang W, Davidson N, Lester HA.

Proc Natl Acad Sci U S A. 1993 Jul 15;90(14):6596-600.

43.
44.

Protein kinase A reduces voltage-dependent Na+ current in Xenopus oocytes.

Gershon E, Weigl L, Lotan I, Schreibmayer W, Dascal N.

J Neurosci. 1992 Oct;12(10):3743-52.

45.

Stereoselective interactions of (R)- and (S)-propafenone with the cardiac sodium channel.

Schreibmayer W, Lindner W.

J Cardiovasc Pharmacol. 1992 Aug;20(2):324-31.

PMID:
1381026
46.

Membrane actions of calcitonin gene-related peptide in cardiac and smooth muscle myocytes.

Tritthart HA, Stark U, Stark G, Mahnert W, Stender CO, Schreibmayer W.

Ann N Y Acad Sci. 1992 Jun 30;657:216-27.

PMID:
1637086
47.

Level of expression controls modes of gating of a K+ channel.

Moran O, Schreibmayer W, Weigl L, Dascal N, Lotan I.

FEBS Lett. 1992 May 4;302(1):21-5.

48.
49.
50.

Molecular mechanism of protein kinase C modulation of sodium channel alpha-subunits expressed in Xenopus oocytes.

Schreibmayer W, Dascal N, Lotan I, Wallner M, Weigl L.

FEBS Lett. 1991 Oct 21;291(2):341-4.

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