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Items: 1 to 50 of 181

1.

FcγRIIa requires lipid rafts, but not co-localization into rafts, for effector function.

Vieth JA, Kim MK, Glaser D, Stiles K, Schreiber AD, Worth RG.

Inflamm Res. 2013 Jan;62(1):37-43. doi: 10.1007/s00011-012-0548-1. Epub 2012 Sep 4.

PMID:
22945762
2.

Effect of locally administered Syk siRNA on allergen-induced arthritis and asthma.

Huang ZY, Kim MK, Kim-Han TH, Indik ZK, Schreiber AD.

Mol Immunol. 2013 Jan;53(1-2):52-9. doi: 10.1016/j.molimm.2012.06.011. Epub 2012 Jul 15.

PMID:
22796951
3.

Human platelet FcγRIIA and phagocytes in immune-complex clearance.

Huang ZY, Chien P, Indik ZK, Schreiber AD.

Mol Immunol. 2011 Jan;48(4):691-6. doi: 10.1016/j.molimm.2010.11.017. Epub 2010 Dec 17.

4.

Fcγ receptor I alpha chain (CD64) expression in macrophages is critical for the onset of meningitis by Escherichia coli K1.

Mittal R, Sukumaran SK, Selvaraj SK, Wooster DG, Babu MM, Schreiber AD, Verbeek JS, Prasadarao NV.

PLoS Pathog. 2010 Nov 18;6(11):e1001203. doi: 10.1371/journal.ppat.1001203.

5.

Interaction of two phagocytic host defense systems: Fcγ receptors and complement receptor 3.

Huang ZY, Hunter S, Chien P, Kim MK, Han-Kim TH, Indik ZK, Schreiber AD.

J Biol Chem. 2011 Jan 7;286(1):160-8. doi: 10.1074/jbc.M110.163030. Epub 2010 Nov 2.

6.

Differential requirement of lipid rafts for FcγRIIA mediated effector activities.

Vieth JA, Kim MK, Pan XQ, Schreiber AD, Worth RG.

Cell Immunol. 2010;265(2):111-9. doi: 10.1016/j.cellimm.2010.07.011. Epub 2010 Aug 1.

7.

Analysis of FcgammaRIIA cytoplasmic tail requirements in signaling for serotonin secretion: evidence for an ITAM-dependent, PI3K-dependent pathway.

Daniels AB, Worth RG, Dickstein RJ, Dickstein JS, Kim-Han TH, Kim MK, Schreiber AD.

Scand J Immunol. 2010 Apr;71(4):232-9. doi: 10.1111/j.1365-3083.2010.02369.x.

8.

Quantitative analysis of membrane remodeling at the phagocytic cup.

Lee WL, Mason D, Schreiber AD, Grinstein S.

Mol Biol Cell. 2007 Aug;18(8):2883-92. Epub 2007 May 16.

9.

Microtubules regulate PI-3K activity and recruitment to the phagocytic cup during Fcgamma receptor-mediated phagocytosis in nonelicited macrophages.

Khandani A, Eng E, Jongstra-Bilen J, Schreiber AD, Douda D, Samavarchi-Tehrani P, Harrison RE.

J Leukoc Biol. 2007 Aug;82(2):417-28. Epub 2007 May 14.

PMID:
17502337
10.

Involvement of Syk kinase in TNF-induced nitric oxide production by airway epithelial cells.

Ulanova M, Marcet-Palacios M, Muñoz S, Asfaha S, Kim MK, Schreiber AD, Befus AD.

Biochem Biophys Res Commun. 2006 Dec 15;351(2):431-7. Epub 2006 Oct 23.

PMID:
17070777
11.

Platelet FcgammaRIIA binds and internalizes IgG-containing complexes.

Worth RG, Chien CD, Chien P, Reilly MP, McKenzie SE, Schreiber AD.

Exp Hematol. 2006 Nov;34(11):1490-5.

PMID:
17046568
12.

Phosphorylation-independent ubiquitylation and endocytosis of Fc gammaRIIA.

Mero P, Zhang CY, Huang ZY, Kim MK, Schreiber AD, Grinstein S, Booth JW.

J Biol Chem. 2006 Nov 3;281(44):33242-9. Epub 2006 Sep 7.

13.

Differential kinase requirements in human and mouse Fc-gamma receptor phagocytosis and endocytosis.

Huang ZY, Barreda DR, Worth RG, Indik ZK, Kim MK, Chien P, Schreiber AD.

J Leukoc Biol. 2006 Dec;80(6):1553-62. Epub 2006 Sep 11.

PMID:
16921024
14.

Differential expression of spleen tyrosine kinase Syk isoforms in tissues: Effects of the microbial flora.

Duta F, Ulanova M, Seidel D, Puttagunta L, Musat-Marcu S, Harrod KS, Schreiber AD, Steinhoff U, Befus AD.

Histochem Cell Biol. 2006 Oct;126(4):495-505. Epub 2006 May 18.

PMID:
16708245
15.

The future of antisense oligonucleotides in the treatment of respiratory diseases.

Ulanova M, Schreiber AD, Befus AD.

BioDrugs. 2006;20(1):1-11. Review.

PMID:
16573347
16.

Spleen tyrosine kinase (Syk) as a novel target for allergic asthma and rhinitis.

Ulanova M, Duta F, Puttagunta L, Schreiber AD, Befus AD.

Expert Opin Ther Targets. 2005 Oct;9(5):901-21. Review.

PMID:
16185147
17.

Role of ubiquitin and proteasomes in phagosome maturation.

Lee WL, Kim MK, Schreiber AD, Grinstein S.

Mol Biol Cell. 2005 Apr;16(4):2077-90. Epub 2005 Feb 9.

18.

Association between monocyte Fcgamma subclass expression and acute coronary syndrome.

Calverley DC, Varteresian T, Brass E, Tsao-Wei DD, Groshen S, Mack WJ, Buchanan TA, Hodis HN, Schreiber AD.

Immun Ageing. 2004 Nov 12;1(1):4.

19.

Immune-mediated hemolytic anemia.

Rosse WF, Hillmen P, Schreiber AD.

Hematology Am Soc Hematol Educ Program. 2004:48-62. Review.

PMID:
15561676
20.

Syk tyrosine kinase participates in beta1-integrin signaling and inflammatory responses in airway epithelial cells.

Ulanova M, Puttagunta L, Marcet-Palacios M, Duszyk M, Steinhoff U, Duta F, Kim MK, Indik ZK, Schreiber AD, Befus AD.

Am J Physiol Lung Cell Mol Physiol. 2005 Mar;288(3):L497-507. Epub 2004 Nov 19.

21.

The monocyte Fcγ receptors FcγRI/γ and FcγRIIA differ in their interaction with Syk and with Src-related tyrosine kinases.

Huang ZY, Hunter S, Kim MK, Chien P, Worth RG, Indik ZK, Schreiber AD.

J Leukoc Biol. 2004 Aug;76(2):491-499. doi: 10.1189/jlb.1103562.

PMID:
29350785
22.

The monocyte Fcgamma receptors FcgammaRI/gamma and FcgammaRIIA differ in their interaction with Syk and with Src-related tyrosine kinases.

Huang ZY, Hunter S, Kim MK, Chien P, Worth RG, Indik ZK, Schreiber AD.

J Leukoc Biol. 2004 Aug;76(2):491-9. Epub 2004 May 10.

PMID:
15136586
23.

Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria.

Vieira OV, Harrison RE, Scott CC, Stenmark H, Alexander D, Liu J, Gruenberg J, Schreiber AD, Grinstein S.

Mol Cell Biol. 2004 May;24(10):4593-604.

24.

Role for platelet-endothelial cell adhesion molecule-1 in macrophage Fcgamma receptor function.

Albelda SM, Lau KC, Chien P, Huang ZY, Arguiris E, Bohen A, Sun J, Billet JA, Christofidou-Solomidou M, Indik ZK, Schreiber AD.

Am J Respir Cell Mol Biol. 2004 Aug;31(2):246-55. Epub 2004 Apr 15.

PMID:
15087304
25.

Antisense oligonucleotides to Syk kinase: a novel therapeutic approach for respiratory disorders.

Ulanova M, Puttagunta L, Kim MK, Schreiber AD, Befus AD.

Curr Opin Investig Drugs. 2003 May;4(5):552-5. Review.

PMID:
12833648
26.

Role for phosphoinositide 3-kinase in Fc gamma RIIA-induced platelet shape change.

Barkalow KL, Falet H, Italiano JE Jr, van Vugt A, Carpenter CL, Schreiber AD, Hartwig JH.

Am J Physiol Cell Physiol. 2003 Oct;285(4):C797-805. Epub 2003 Jun 4.

27.

The effect of phosphatases SHP-1 and SHIP-1 on signaling by the ITIM- and ITAM-containing Fcgamma receptors FcgammaRIIB and FcgammaRIIA.

Huang ZY, Hunter S, Kim MK, Indik ZK, Schreiber AD.

J Leukoc Biol. 2003 Jun;73(6):823-9.

PMID:
12773515
28.

Fcgamma receptor transmembrane domains: role in cell surface expression, gamma chain interaction, and phagocytosis.

Kim MK, Huang ZY, Hwang PH, Jones BA, Sato N, Hunter S, Kim-Han TH, Worth RG, Indik ZK, Schreiber AD.

Blood. 2003 Jun 1;101(11):4479-84.

PMID:
12756162
29.

Signal sequence within Fc gamma RIIA controls calcium wave propagation patterns: apparent role in phagolysosome fusion.

Worth RG, Kim MK, Kindzelskii AL, Petty HR, Schreiber AD.

Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4533-8. Epub 2003 Apr 3.

30.

Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase.

Vieira OV, Bucci C, Harrison RE, Trimble WS, Lanzetti L, Gruenberg J, Schreiber AD, Stahl PD, Grinstein S.

Mol Cell Biol. 2003 Apr;23(7):2501-14.

31.

The carboxy-terminal region of the granulocyte colony-stimulating factor receptor transduces a phagocytic signal.

Santini V, Scappini B, Indik ZK, Gozzini A, Ferrini PR, Schreiber AD.

Blood. 2003 Jun 1;101(11):4615-22. Epub 2003 Feb 13.

PMID:
12586631
32.

Enhanced phagocytosis through inhibition of de novo ceramide synthesis.

Hinkovska-Galcheva V, Boxer L, Mansfield PJ, Schreiber AD, Shayman JA.

J Biol Chem. 2003 Jan 10;278(2):974-82. Epub 2002 Nov 6.

33.

Differential role of actin, clathrin, and dynamin in Fc gamma receptor-mediated endocytosis and phagocytosis.

Tse SM, Furuya W, Gold E, Schreiber AD, Sandvig K, Inman RD, Grinstein S.

J Biol Chem. 2003 Jan 31;278(5):3331-8. Epub 2002 Nov 6.

34.

Inhibition of phosphatidylinositol-4-phosphate 5-kinase Ialpha impairs localized actin remodeling and suppresses phagocytosis.

Coppolino MG, Dierckman R, Loijens J, Collins RF, Pouladi M, Jongstra-Bilen J, Schreiber AD, Trimble WS, Anderson R, Grinstein S.

J Biol Chem. 2002 Nov 15;277(46):43849-57. Epub 2002 Sep 9.

35.

Syntaxins 13 and 7 function at distinct steps during phagocytosis.

Collins RF, Schreiber AD, Grinstein S, Trimble WS.

J Immunol. 2002 Sep 15;169(6):3250-6.

36.

The CY domain of the Fcgamma RIa alpha-chain (CD64) alters gamma-chain tyrosine-based signaling and phagocytosis.

Edberg JC, Qin H, Gibson AW, Yee AM, Redecha PB, Indik ZK, Schreiber AD, Kimberly RP.

J Biol Chem. 2002 Oct 25;277(43):41287-93. Epub 2002 Aug 27.

37.

Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase.

Stenton GR, Ulanova M, Déry RE, Merani S, Kim MK, Gilchrist M, Puttagunta L, Musat-Marcu S, James D, Schreiber AD, Befus AD.

J Immunol. 2002 Jul 15;169(2):1028-36.

38.

Contrasting requirements for ubiquitylation during Fc receptor-mediated endocytosis and phagocytosis.

Booth JW, Kim MK, Jankowski A, Schreiber AD, Grinstein S.

EMBO J. 2002 Feb 1;21(3):251-8.

39.

The cytoplasmic domain of FcgammaRIIA (CD32) participates in phagolysosome formation.

Worth RG, Mayo-Bond L, Kim MK, van de Winkel JG, Todd RF 3rd, Petty HR, Schreiber AD.

Blood. 2001 Dec 1;98(12):3429-34.

PMID:
11719384
40.

Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fc gamma receptor-mediated phagocytosis.

Marshall JG, Booth JW, Stambolic V, Mak T, Balla T, Schreiber AD, Meyer T, Grinstein S.

J Cell Biol. 2001 Jun 25;153(7):1369-80.

41.

Indirect role for COPI in the completion of FCgamma receptor-mediated phagocytosis.

Hackam DJ, Botelho RJ, Sjolin C, Rotstein OD, Robinson JM, Schreiber AD, Grinstein S.

J Biol Chem. 2001 May 25;276(21):18200-8. Epub 2001 Mar 15.

42.

Serum lipids and arterial plaque load are altered independently with high-dose progesterone in hypercholesterolemic male rabbits.

Houser SL, Aretz HT, Quist WC, Chang Y, Schreiber AD.

Cardiovasc Pathol. 2000 Nov-Dec;9(6):317-22.

PMID:
11146301
43.

Fc gamma receptors differ in their structural requirements for interaction with the tyrosine kinase Syk in the initial steps of signaling for phagocytosis.

Kim MK, Pan XQ, Huang ZY, Hunter S, Hwang PH, Indik ZK, Schreiber AD.

Clin Immunol. 2001 Jan;98(1):125-32.

PMID:
11141335
44.

Thrombosis and shock induced by activating antiplatelet antibodies in human Fc gamma RIIA transgenic mice: the interplay among antibody, spleen, and Fc receptor.

Taylor SM, Reilly MP, Schreiber AD, Chien P, Tuckosh JR, McKenzie SE.

Blood. 2000 Dec 15;96(13):4254-60.

PMID:
11110699
45.

Requirement for N-ethylmaleimide-sensitive factor activity at different stages of bacterial invasion and phagocytosis.

Coppolino MG, Kong C, Mohtashami M, Schreiber AD, Brumell JH, Finlay BB, Grinstein S, Trimble WS.

J Biol Chem. 2001 Feb 16;276(7):4772-80. Epub 2000 Nov 22.

46.

Focal exocytosis of VAMP3-containing vesicles at sites of phagosome formation.

Bajno L, Peng XR, Schreiber AD, Moore HP, Trimble WS, Grinstein S.

J Cell Biol. 2000 May 1;149(3):697-706.

47.

Role of COPI in phagosome maturation.

Botelho RJ, Hackam DJ, Schreiber AD, Grinstein S.

J Biol Chem. 2000 May 26;275(21):15717-27.

48.

Target site search and effective inhibition of leukaemic cell growth by a covalently closed multiple anti-sense oligonucleotide to c-myb.

Moon IJ, Lee Y, Kwak CS, Lee JH, Choi K, Schreiber AD, Park JG.

Biochem J. 2000 Mar 1;346 Pt 2:295-303.

49.

Aerosolized Syk antisense suppresses Syk expression, mediator release from macrophages, and pulmonary inflammation.

Stenton GR, Kim MK, Nohara O, Chen CF, Hirji N, Wills FL, Gilchrist M, Hwang PH, Park JG, Finlay W, Jones RL, Befus AD, Schreiber AD.

J Immunol. 2000 Apr 1;164(7):3790-7. Erratum in: J Immunol 2000 May 15;164(10):5532.

50.

Potent growth inhibition of leukemic cells by novel ribbon-type antisense oligonucleotides to c-myb1.

Moon IJ, Choi K, Choi YK, Kim JE, Lee Y, Schreiber AD, Park JG.

J Biol Chem. 2000 Feb 18;275(7):4647-53.

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