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Items: 28


Integrating Biomarkers in Social Stratification and Health Research.

Harris KM, Schorpp KM.

Annu Rev Sociol. 2018 Jul;44:361-386. doi: 10.1146/annurev-soc-060116-053339. Epub 2018 May 16.


Inhibition of CPAP-tubulin interaction prevents proliferation of centrosome-amplified cancer cells.

Mariappan A, Soni K, Schorpp K, Zhao F, Minakar A, Zheng X, Mandad S, Macheleidt I, Ramani A, Kubelka T, Dawidowski M, Golfmann K, Wason A, Yang C, Simons J, Schmalz HG, Hyman AA, Aneja R, Ullrich R, Urlaub H, Odenthal M, Büttner R, Li H, Sattler M, Hadian K, Gopalakrishnan J.

EMBO J. 2019 Jan 15;38(2). pii: e99876. doi: 10.15252/embj.201899876. Epub 2018 Dec 10.


Socioeconomic Status and Biological Risks for Health and Illness across the Life Course.

Yang YC, Schorpp K, Boen C, Johnson M, Kathleen MH.

J Gerontol B Psychol Sci Soc Sci. 2018 Sep 25. doi: 10.1093/geronb/gby108. [Epub ahead of print]


Targeting TRAF6 E3 ligase activity with a small-molecule inhibitor combats autoimmunity.

Brenke JK, Popowicz GM, Schorpp K, Rothenaigner I, Roesner M, Meininger I, Kalinski C, Ringelstetter L, R'kyek O, Jürjens G, Vincendeau M, Plettenburg O, Sattler M, Krappmann D, Hadian K.

J Biol Chem. 2018 Aug 24;293(34):13191-13203. doi: 10.1074/jbc.RA118.002649. Epub 2018 Jun 27.


Religious Pathways from Adolescence to Adulthood.

Lee BHJ, Pearce LD, Schorpp KM.

J Sci Study Relig. 2017 Sep;56(3):678-689. doi: 10.1111/jssr.12367. Epub 2018 Mar 14.


A high-content screen for small-molecule regulators of epithelial cell-adhesion molecule (EpCAM) cleavage yields a robust inhibitor.

Tretter JY, Schorpp K, Luxenburger E, Trambauer J, Steiner H, Hadian K, Gires O, Niessing D.

J Biol Chem. 2018 Jun 8;293(23):8994-9005. doi: 10.1074/jbc.RA118.002776. Epub 2018 Apr 26.


Reducing Mutant Huntingtin Protein Expression in Living Cells by a Newly Identified RNA CAG Binder.

Matthes F, Massari S, Bochicchio A, Schorpp K, Schilling J, Weber S, Offermann N, Desantis J, Wanker E, Carloni P, Hadian K, Tabarrini O, Rossetti G, Krauss S.

ACS Chem Neurosci. 2018 Jun 20;9(6):1399-1408. doi: 10.1021/acschemneuro.8b00027. Epub 2018 Mar 14.


College completion predicts lower depression but higher metabolic syndrome among disadvantaged minorities in young adulthood.

Gaydosh L, Schorpp KM, Chen E, Miller GE, Harris KM.

Proc Natl Acad Sci U S A. 2018 Jan 2;115(1):109-114. doi: 10.1073/pnas.1714616114. Epub 2017 Dec 18.


Young Adult Risk Factors for Cancer: Obesity, Inflammation, and Sociobehavioral Mechanisms.

Yang YC, Johnson MP, Schorpp KM, Boen CE, Harris KM.

Am J Prev Med. 2017 Sep;53(3S1):S21-S29. doi: 10.1016/j.amepre.2017.04.025.


An in vivo high-throughput screening for riboswitch ligands using a reverse reporter gene system.

Kirchner M, Schorpp K, Hadian K, Schneider S.

Sci Rep. 2017 Aug 10;7(1):7732. doi: 10.1038/s41598-017-07870-w.


A high-content small molecule screen identifies novel inducers of definitive endoderm.

Korostylev A, Mahaddalkar PU, Keminer O, Hadian K, Schorpp K, Gribbon P, Lickert H.

Mol Metab. 2017 May 4;6(7):640-650. doi: 10.1016/j.molmet.2017.04.009. eCollection 2017 Jul.


Early-Life Socioeconomic Status and Adult Physiological Functioning: A Life Course Examination of Biosocial Mechanisms.

Yang YC, Gerken K, Schorpp K, Boen C, Harris KM.

Biodemography Soc Biol. 2017;63(2):87-103. doi: 10.1080/19485565.2017.1279536.


Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.

Dawidowski M, Emmanouilidis L, Kalel VC, Tripsianes K, Schorpp K, Hadian K, Kaiser M, Mäser P, Kolonko M, Tanghe S, Rodriguez A, Schliebs W, Erdmann R, Sattler M, Popowicz GM.

Science. 2017 Mar 31;355(6332):1416-1420. doi: 10.1126/science.aal1807.


YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB.

Schimmack G, Schorpp K, Kutzner K, Gehring T, Brenke JK, Hadian K, Krappmann D.

Elife. 2017 Feb 28;6. pii: e22416. doi: 10.7554/eLife.22416.


A High-Throughput Screening Strategy for Development of RNF8-Ubc13 Protein-Protein Interaction Inhibitors.

Weber E, Rothenaigner I, Brandner S, Hadian K, Schorpp K.

SLAS Discov. 2017 Mar;22(3):316-323. doi: 10.1177/1087057116681408. Epub 2016 Dec 13.


Developmental timing of suicide attempts and cardiovascular risk during young adulthood.

Shanahan L, Schorpp KM, Volpe VV, Linthicum K, Freeman JA.

Health Psychol. 2016 Oct;35(10):1135-43. doi: 10.1037/hea0000373. Epub 2016 Jun 6.


A Multiplexed High-Content Screening Approach Using the Chromobody Technology to Identify Cell Cycle Modulators in Living Cells.

Schorpp K, Rothenaigner I, Maier J, Traenkle B, Rothbauer U, Hadian K.

J Biomol Screen. 2016 Oct;21(9):965-77. doi: 10.1177/1087057116641935. Epub 2016 Apr 4.


Identification of Small-Molecule Frequent Hitters of Glutathione S-Transferase-Glutathione Interaction.

Brenke JK, Salmina ES, Ringelstetter L, Dornauer S, Kuzikov M, Rothenaigner I, Schorpp K, Giehler F, Gopalakrishnan J, Kieser A, Gul S, Tetko IV, Hadian K.

J Biomol Screen. 2016 Jul;21(6):596-607. doi: 10.1177/1087057116639992. Epub 2016 Apr 4.


Novel small molecules targeting ciliary transport of Smoothened and oncogenic Hedgehog pathway activation.

Jung B, Messias AC, Schorpp K, Geerlof A, Schneider G, Saur D, Hadian K, Sattler M, Wanker EE, Hasenöder S, Lickert H.

Sci Rep. 2016 Mar 2;6:22540. doi: 10.1038/srep22540.


Three-dimensional microtissues essentially contribute to preclinical validations of therapeutic targets in breast cancer.

Falkenberg N, Höfig I, Rosemann M, Szumielewski J, Richter S, Schorpp K, Hadian K, Aubele M, Atkinson MJ, Anastasov N.

Cancer Med. 2016 Apr;5(4):703-10. doi: 10.1002/cam4.630. Epub 2016 Jan 14.


Social relationships and physiological determinants of longevity across the human life span.

Yang YC, Boen C, Gerken K, Li T, Schorpp K, Harris KM.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):578-83. doi: 10.1073/pnas.1511085112. Epub 2016 Jan 4.


Development of A Cell-Based Assay to Identify Small Molecule Inhibitors of FGF23 Signaling.

Diener S, Schorpp K, Strom TM, Hadian K, Lorenz-Depiereux B.

Assay Drug Dev Technol. 2015 Oct;13(8):476-87. doi: 10.1089/adt.2015.653.


New small molecules targeting apoptosis and cell viability in osteosarcoma.

Maugg D, Rothenaigner I, Schorpp K, Potukuchi HK, Korsching E, Baumhoer D, Hadian K, Smida J, Nathrath M.

PLoS One. 2015 Jun 3;10(6):e0129058. doi: 10.1371/journal.pone.0129058. eCollection 2015.


Social support, social strain and inflammation: evidence from a national longitudinal study of U.S. adults.

Yang YC, Schorpp K, Harris KM.

Soc Sci Med. 2014 Apr;107:124-35. doi: 10.1016/j.socscimed.2014.02.013. Epub 2014 Feb 14.


Small molecule screening at Helmholtz Zentrum München - from biology to molecules.

Schorpp K, Hadian K.

Comb Chem High Throughput Screen. 2014 Mar;17(3):266-71.


Identification of Small-Molecule Frequent Hitters from AlphaScreen High-Throughput Screens.

Schorpp K, Rothenaigner I, Salmina E, Reinshagen J, Low T, Brenke JK, Gopalakrishnan J, Tetko IV, Gul S, Hadian K.

J Biomol Screen. 2014 Jun;19(5):715-26. doi: 10.1177/1087057113516861. Epub 2013 Dec 26.


Role of the ubiquitin-like protein Urm1 as a noncanonical lysine-directed protein modifier.

Van der Veen AG, Schorpp K, Schlieker C, Buti L, Damon JR, Spooner E, Ploegh HL, Jentsch S.

Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):1763-70. doi: 10.1073/pnas.1014402108. Epub 2011 Jan 5.


Effects of acute and repeated administration of Staphylococcal enterotoxin A on Morris water maze learning, corticosterone and hippocampal IL-1β and TNFα.

Woodruff RT, Schorpp KM, Lawrenczyk AJ, Chakraborty T, Kusnecov AW.

Brain Behav Immun. 2011 Jul;25(5):938-46. doi: 10.1016/j.bbi.2010.10.005. Epub 2010 Oct 12.

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