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Items: 1 to 50 of 59

1.

Activation of endothelial cells by extracellular vesicles derived from Mycobacterium tuberculosis infected macrophages or mice.

Li L, Cheng Y, Emrich S, Schorey J.

PLoS One. 2018 May 31;13(5):e0198337. doi: 10.1371/journal.pone.0198337. eCollection 2018.

2.

Protein Digestion, Ultrafiltration, and Size Exclusion Chromatography to Optimize the Isolation of Exosomes from Human Blood Plasma and Serum.

Diaz G, Bridges C, Lucas M, Cheng Y, Schorey JS, Dobos KM, Kruh-Garcia NA.

J Vis Exp. 2018 Apr 13;(134). doi: 10.3791/57467.

PMID:
29708539
3.

Regulation and mechanisms of extracellular vesicle biogenesis and secretion.

D'Souza-Schorey C, Schorey JS.

Essays Biochem. 2018 May 15;62(2):125-133. doi: 10.1042/EBC20170078. Print 2018 May 15. Review.

PMID:
29666210
4.

Biomarkers of Tuberculosis Severity and Treatment Effect: A Directed Screen of 70 Host Markers in a Randomized Clinical Trial.

Sigal GB, Segal MR, Mathew A, Jarlsberg L, Wang M, Barbero S, Small N, Haynesworth K, Davis JL, Weiner M, Whitworth WC, Jacobs J, Schorey J, Lewinsohn DM, Nahid P.

EBioMedicine. 2017 Nov;25:112-121. doi: 10.1016/j.ebiom.2017.10.018. Epub 2017 Oct 24.

5.

A novel method for intratracheal injection of infectious agents into mice.

Cheng Y, Liepert LD, Waller J, Leevy WM, Schorey JS.

Lab Anim. 2017 Oct;51(5):530-533. doi: 10.1177/0023677216684422. Epub 2016 Dec 20.

PMID:
28948897
6.

Protein Kinase Inhibitors as Potential Antimicrobial Drugs Against Tuberculosis, Malaria and HIV.

Cheng Y, Schorey JS, Zhang CC, Tan X.

Curr Pharm Des. 2017 Nov 16;23(29):4369-4389. doi: 10.2174/1381612823666170612122429.

PMID:
28606053
7.

Exosomes function in antigen presentation during an in vivo Mycobacterium tuberculosis infection.

Smith VL, Cheng Y, Bryant BR, Schorey JS.

Sci Rep. 2017 Mar 6;7:43578. doi: 10.1038/srep43578.

8.

Innate Immune Responses to Tuberculosis.

Schorey JS, Schlesinger LS.

Microbiol Spectr. 2016 Dec;4(6). doi: 10.1128/microbiolspec.TBTB2-0010-2016. Review.

PMID:
28087945
9.

Imidazo[1,2-a]Pyridine-3-Carboxamides Are Active Antimicrobial Agents against Mycobacterium avium Infection In Vivo.

Moraski GC, Cheng Y, Cho S, Cramer JW, Godfrey A, Masquelin T, Franzblau SG, Miller MJ, Schorey J.

Antimicrob Agents Chemother. 2016 Jul 22;60(8):5018-22. doi: 10.1128/AAC.00618-16. Print 2016 Aug.

10.

Extracellular vesicles and infectious diseases: new complexity to an old story.

Schorey JS, Harding CV.

J Clin Invest. 2016 Apr 1;126(4):1181-9. doi: 10.1172/JCI81132. Epub 2016 Apr 1. Review.

11.

Targeting soluble proteins to exosomes using a ubiquitin tag.

Cheng Y, Schorey JS.

Biotechnol Bioeng. 2016 Jun;113(6):1315-24. doi: 10.1002/bit.25884. Epub 2015 Dec 17.

PMID:
26574179
12.

Ubiquitination as a Mechanism To Transport Soluble Mycobacterial and Eukaryotic Proteins to Exosomes.

Smith VL, Jackson L, Schorey JS.

J Immunol. 2015 Sep 15;195(6):2722-30. doi: 10.4049/jimmunol.1403186. Epub 2015 Aug 5.

13.

Exosomal RNA from Mycobacterium tuberculosis-Infected Cells Is Functional in Recipient Macrophages.

Singh PP, Li L, Schorey JS.

Traffic. 2015 Jun;16(6):555-71. doi: 10.1111/tra.12278. Epub 2015 Apr 16.

14.

Exosomes and other extracellular vesicles in host-pathogen interactions.

Schorey JS, Cheng Y, Singh PP, Smith VL.

EMBO Rep. 2015 Jan;16(1):24-43. doi: 10.15252/embr.201439363. Epub 2014 Dec 8. Review.

15.

Detection of Mycobacterium tuberculosis peptides in the exosomes of patients with active and latent M. tuberculosis infection using MRM-MS.

Kruh-Garcia NA, Wolfe LM, Chaisson LH, Worodria WO, Nahid P, Schorey JS, Davis JL, Dobos KM.

PLoS One. 2014 Jul 31;9(7):e103811. doi: 10.1371/journal.pone.0103811. eCollection 2014.

16.

Bactericidal activity of an imidazo[1, 2-a]pyridine using a mouse M. tuberculosis infection model.

Cheng Y, Moraski GC, Cramer J, Miller MJ, Schorey JS.

PLoS One. 2014 Jan 31;9(1):e87483. doi: 10.1371/journal.pone.0087483. eCollection 2014.

17.

Exosomes carrying mycobacterial antigens can protect mice against Mycobacterium tuberculosis infection.

Cheng Y, Schorey JS.

Eur J Immunol. 2013 Dec;43(12):3279-90. doi: 10.1002/eji.201343727. Epub 2013 Sep 6.

18.

Leishmania major inhibits IL-12 in macrophages by signalling through CR3 (CD11b/CD18) and down-regulation of ETS-mediated transcription.

Ricardo-Carter C, Favila M, Polando RE, Cotton RN, Bogard Horner K, Condon D, Ballhorn W, Whitcomb JP, Yadav M, Geister RL, Schorey JS, McDowell MA.

Parasite Immunol. 2013 Dec;35(12):409-20. doi: 10.1111/pim.12049.

19.

Exosomes isolated from mycobacteria-infected mice or cultured macrophages can recruit and activate immune cells in vitro and in vivo.

Singh PP, Smith VL, Karakousis PC, Schorey JS.

J Immunol. 2012 Jul 15;189(2):777-85. doi: 10.4049/jimmunol.1103638. Epub 2012 Jun 20.

20.

Exosomes released from M. tuberculosis infected cells can suppress IFN-γ mediated activation of naïve macrophages.

Singh PP, LeMaire C, Tan JC, Zeng E, Schorey JS.

PLoS One. 2011 Apr 14;6(4):e18564. doi: 10.1371/journal.pone.0018564.

21.

Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages.

Giri PK, Kruh NA, Dobos KM, Schorey JS.

Proteomics. 2010 Sep;10(17):3190-202. doi: 10.1002/pmic.200900840.

22.

Mannose receptor-dependent delay in phagosome maturation by Mycobacterium avium glycopeptidolipids.

Sweet L, Singh PP, Azad AK, Rajaram MV, Schlesinger LS, Schorey JS.

Infect Immun. 2010 Jan;78(1):518-26. doi: 10.1128/IAI.00257-09. Epub 2009 Oct 19.

23.

Toll-like receptor signaling in hen ovarian granulosa cells is dependent on stage of follicle maturation.

Woods DC, Schorey JS, Johnson AL.

Reproduction. 2009 Jun;137(6):987-96. doi: 10.1530/REP-08-0320. Epub 2009 Mar 31.

24.

ADP-ribosylation factor 6 regulates tumorigenic and invasive properties in vivo.

Muralidharan-Chari V, Hoover H, Clancy J, Schweitzer J, Suckow MA, Schroeder V, Castellino FJ, Schorey JS, D'Souza-Schorey C.

Cancer Res. 2009 Mar 15;69(6):2201-9. doi: 10.1158/0008-5472.CAN-08-1301. Epub 2009 Mar 10.

25.

Mycobacterium avium glycopeptidolipids require specific acetylation and methylation patterns for signaling through toll-like receptor 2.

Sweet L, Zhang W, Torres-Fewell H, Serianni A, Boggess W, Schorey J.

J Biol Chem. 2008 Nov 28;283(48):33221-31. doi: 10.1074/jbc.M805539200. Epub 2008 Sep 29.

26.

The mycobacterial glycopeptidolipids: structure, function, and their role in pathogenesis.

Schorey JS, Sweet L.

Glycobiology. 2008 Nov;18(11):832-41. doi: 10.1093/glycob/cwn076. Epub 2008 Aug 22. Review.

27.
28.

Exosome function: from tumor immunology to pathogen biology.

Schorey JS, Bhatnagar S.

Traffic. 2008 Jun;9(6):871-81. doi: 10.1111/j.1600-0854.2008.00734.x. Epub 2008 Mar 6. Review.

29.

The pattern recognition receptor Dectin-1: from fungi to mycobacteria.

Schorey JS, Lawrence C.

Curr Drug Targets. 2008 Feb;9(2):123-9. Review.

30.

Exosomes released from macrophages infected with intracellular pathogens stimulate a proinflammatory response in vitro and in vivo.

Bhatnagar S, Shinagawa K, Castellino FJ, Schorey JS.

Blood. 2007 Nov 1;110(9):3234-44. Epub 2007 Jul 31.

31.

Exosomes released from infected macrophages contain Mycobacterium avium glycopeptidolipids and are proinflammatory.

Bhatnagar S, Schorey JS.

J Biol Chem. 2007 Aug 31;282(35):25779-89. Epub 2007 Jun 25.

32.
33.

Glycopeptidolipids from Mycobacterium avium promote macrophage activation in a TLR2- and MyD88-dependent manner.

Sweet L, Schorey JS.

J Leukoc Biol. 2006 Aug;80(2):415-23. Epub 2006 Jun 7.

PMID:
16760377
37.
40.

Naturally occurring horizontal gene transfer and homologous recombination in Mycobacterium.

Krzywinska E, Krzywinski J, Schorey JS.

Microbiology. 2004 Jun;150(Pt 6):1707-12.

PMID:
15184557
41.

Phylogeny of Mycobacterium avium strains inferred from glycopeptidolipid biosynthesis pathway genes.

Krzywinska E, Krzywinski J, Schorey JS.

Microbiology. 2004 Jun;150(Pt 6):1699-706.

PMID:
15184556
43.
44.

The fibrinolytic system in dissemination and matrix protein deposition during a mycobacterium infection.

Sato J, Schorey J, Ploplis VA, Haalboom E, Krahule L, Castellino FJ.

Am J Pathol. 2003 Aug;163(2):517-31.

45.

Macrophage signalling upon mycobacterial infection: the MAP kinases lead the way.

Schorey JS, Cooper AM.

Cell Microbiol. 2003 Mar;5(3):133-42. Review.

PMID:
12614457
47.
49.

Role of a bacillus Calmette-Guérin fibronectin attachment protein in BCG-induced antitumor activity.

Zhao W, Schorey JS, Bong-Mastek M, Ritchey J, Brown EJ, Ratliff TL.

Int J Cancer. 2000 Apr 1;86(1):83-8.

50.

NK lytic-associated molecule: a novel gene selectively expressed in cells with cytolytic function.

Kozlowski M, Schorey J, Portis T, Grigoriev V, Kornbluth J.

J Immunol. 1999 Aug 15;163(4):1775-85.

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