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Items: 38

2.

CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.

Camacho-Pereira J, Tarragó MG, Chini CCS, Nin V, Escande C, Warner GM, Puranik AS, Schoon RA, Reid JM, Galina A, Chini EN.

Cell Metab. 2016 Jun 14;23(6):1127-1139. doi: 10.1016/j.cmet.2016.05.006.

3.

Identification of HDAC6-Selective Inhibitors of Low Cancer Cell Cytotoxicity.

Gaisina IN, Tueckmantel W, Ugolkov A, Shen S, Hoffen J, Dubrovskyi O, Mazar A, Schoon RA, Billadeau D, Kozikowski AP.

ChemMedChem. 2016 Jan 5;11(1):81-92. doi: 10.1002/cmdc.201500456. Epub 2015 Nov 23.

4.

HkRP3 is a microtubule-binding protein regulating lytic granule clustering and NK cell killing.

Ham H, Huynh W, Schoon RA, Vale RD, Billadeau DD.

J Immunol. 2015 Apr 15;194(8):3984-96. doi: 10.4049/jimmunol.1402897. Epub 2015 Mar 11.

5.

Dedicator of cytokinesis 8 interacts with talin and Wiskott-Aldrich syndrome protein to regulate NK cell cytotoxicity.

Ham H, Guerrier S, Kim J, Schoon RA, Anderson EL, Hamann MJ, Lou Z, Billadeau DD.

J Immunol. 2013 Apr 1;190(7):3661-9. doi: 10.4049/jimmunol.1202792. Epub 2013 Mar 1.

6.

WASH knockout T cells demonstrate defective receptor trafficking, proliferation, and effector function.

Piotrowski JT, Gomez TS, Schoon RA, Mangalam AK, Billadeau DD.

Mol Cell Biol. 2013 Mar;33(5):958-73. doi: 10.1128/MCB.01288-12. Epub 2012 Dec 28.

7.

The cytoskeletal adaptor protein IQGAP1 regulates TCR-mediated signaling and filamentous actin dynamics.

Gorman JA, Babich A, Dick CJ, Schoon RA, Koenig A, Gomez TS, Burkhardt JK, Billadeau DD.

J Immunol. 2012 Jun 15;188(12):6135-44. doi: 10.4049/jimmunol.1103487. Epub 2012 May 9.

8.

2B4 utilizes ITAM-containing receptor complexes to initiate intracellular signaling and cytolysis.

Bida AT, Upshaw Neff JL, Dick CJ, Schoon RA, Brickshawana A, Chini CC, Billadeau DD.

Mol Immunol. 2011 May;48(9-10):1149-59. doi: 10.1016/j.molimm.2011.02.008. Epub 2011 Mar 25.

9.

PI3K links NKG2D signaling to a CrkL pathway involved in natural killer cell adhesion, polarity, and granule secretion.

Segovis CM, Schoon RA, Dick CJ, Nacusi LP, Leibson PJ, Billadeau DD.

J Immunol. 2009 Jun 1;182(11):6933-42. doi: 10.4049/jimmunol.0803840.

10.

Novel acridine-based compounds that exhibit an anti-pancreatic cancer activity are catalytic inhibitors of human topoisomerase II.

Oppegard LM, Ougolkov AV, Luchini DN, Schoon RA, Goodell JR, Kaur H, Billadeau DD, Ferguson DM, Hiasa H.

Eur J Pharmacol. 2009 Jan 14;602(2-3):223-9. doi: 10.1016/j.ejphar.2008.11.044. Epub 2008 Dec 3.

11.

Dynamin 2 regulates granule exocytosis during NK cell-mediated cytotoxicity.

Arneson LN, Segovis CM, Gomez TS, Schoon RA, Dick CJ, Lou Z, Billadeau DD, Leibson PJ.

J Immunol. 2008 Nov 15;181(10):6995-7001.

12.

Cutting edge: syntaxin 11 regulates lymphocyte-mediated secretion and cytotoxicity.

Arneson LN, Brickshawana A, Segovis CM, Schoon RA, Dick CJ, Leibson PJ.

J Immunol. 2007 Sep 15;179(6):3397-401.

13.

Differential regulation of human NK cell-mediated cytotoxicity by the tyrosine kinase Itk.

Khurana D, Arneson LN, Schoon RA, Dick CJ, Leibson PJ.

J Immunol. 2007 Mar 15;178(6):3575-82.

14.

NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells.

Upshaw JL, Arneson LN, Schoon RA, Dick CJ, Billadeau DD, Leibson PJ.

Nat Immunol. 2006 May;7(5):524-32. Epub 2006 Apr 2.

PMID:
16582911
15.

The isoforms of phospholipase C-gamma are differentially used by distinct human NK activating receptors.

Upshaw JL, Schoon RA, Dick CJ, Billadeau DD, Leibson PJ.

J Immunol. 2005 Jul 1;175(1):213-8.

16.

NKG2D-DAP10 triggers human NK cell-mediated killing via a Syk-independent regulatory pathway.

Billadeau DD, Upshaw JL, Schoon RA, Dick CJ, Leibson PJ.

Nat Immunol. 2003 Jun;4(6):557-64. Epub 2003 May 11.

PMID:
12740575
17.

A role for a RhoA/ROCK/LIM-kinase pathway in the regulation of cytotoxic lymphocytes.

Lou Z, Billadeau DD, Savoy DN, Schoon RA, Leibson PJ.

J Immunol. 2001 Nov 15;167(10):5749-57.

18.

Regulation of NK cell-mediated cytotoxicity by the adaptor protein 3BP2.

Jevremovic D, Billadeau DD, Schoon RA, Dick CJ, Leibson PJ.

J Immunol. 2001 Jun 15;166(12):7219-28.

19.

Specific subdomains of Vav differentially affect T cell and NK cell activation.

Billadeau DD, Mackie SM, Schoon RA, Leibson PJ.

J Immunol. 2000 Apr 15;164(8):3971-81.

20.

Regulation of p38 mitogen-activated protein kinase during NK cell activation.

Chini CC, Boos MD, Dick CJ, Schoon RA, Leibson PJ.

Eur J Immunol. 2000 Oct;30(10):2791-8.

21.

The Rho family guanine nucleotide exchange factor Vav-2 regulates the development of cell-mediated cytotoxicity.

Billadeau DD, Mackie SM, Schoon RA, Leibson PJ.

J Exp Med. 2000 Aug 7;192(3):381-92.

22.

Cutting edge: a role for the adaptor protein LAT in human NK cell-mediated cytotoxicity.

Jevremovic D, Billadeau DD, Schoon RA, Dick CJ, Irvin BJ, Zhang W, Samelson LE, Abraham RT, Leibson PJ.

J Immunol. 1999 Mar 1;162(5):2453-6.

23.

The Vav-Rac1 pathway in cytotoxic lymphocytes regulates the generation of cell-mediated killing.

Billadeau DD, Brumbaugh KM, Dick CJ, Schoon RA, Bustelo XR, Leibson PJ.

J Exp Med. 1998 Aug 3;188(3):549-59.

24.

Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity.

Brumbaugh KM, Binstadt BA, Billadeau DD, Schoon RA, Dick CJ, Ten RM, Leibson PJ.

J Exp Med. 1997 Dec 15;186(12):1965-74.

25.

Clonotypic differences in signaling from CD94 (kp43) on NK cells lead to divergent cellular responses.

Brumbaugh KM, Pérez-Villar JJ, Dick CJ, Schoon RA, López-Botet M, Leibson PJ.

J Immunol. 1996 Oct 1;157(7):2804-12.

PMID:
8816383
26.

Fc receptor stimulation of PI 3-kinase in NK cells is associated with protein kinase C-independent granule release and cell-mediated cytotoxicity.

Bonnema JD, Karnitz LM, Schoon RA, Abraham RT, Leibson PJ.

Ann N Y Acad Sci. 1995 Sep 7;766:209-13. No abstract available.

PMID:
7486660
27.

Interaction between lck and syk family tyrosine kinases in Fc gamma receptor-initiated activation of natural killer cells.

Ting AT, Dick CJ, Schoon RA, Karnitz LM, Abraham RT, Leibson PJ.

J Biol Chem. 1995 Jul 7;270(27):16415-21.

28.

Inhibition of selective signaling events in natural killer cells recognizing major histocompatibility complex class I.

Kaufman DS, Schoon RA, Robertson MJ, Leibson PJ.

Proc Natl Acad Sci U S A. 1995 Jul 3;92(14):6484-8.

30.

Cytokine-enhanced NK cell-mediated cytotoxicity. Positive modulatory effects of IL-2 and IL-12 on stimulus-dependent granule exocytosis.

Bonnema JD, Rivlin KA, Ting AT, Schoon RA, Abraham RT, Leibson PJ.

J Immunol. 1994 Mar 1;152(5):2098-104.

PMID:
7907631
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35.

Defective T-lymphocyte signal transduction and function in leukocyte adhesion deficiency.

Voss LM, Abraham RT, Rhodes KH, Schoon RA, Leibson PJ.

J Clin Immunol. 1991 Jul;11(4):175-83.

PMID:
1918265
36.

Alternative mechanisms of natural killer cell activation during herpes simplex virus infection.

Paya CV, Schoon RA, Leibson PJ.

J Immunol. 1990 Jun 1;144(11):4370-5.

PMID:
2160501
37.

Heteroconjugate antibodies enhance cell-mediated anti-herpes simplex virus immunity.

Paya CV, McKean DJ, Segal DM, Schoon RA, Showalter SD, Leibson PJ.

J Immunol. 1989 Jan 15;142(2):666-71.

PMID:
2536060
38.

Tumor necrosis factor and lymphotoxin secretion by human natural killer cells leads to antiviral cytotoxicity.

Paya CV, Kenmotsu N, Schoon RA, Leibson PJ.

J Immunol. 1988 Sep 15;141(6):1989-95.

PMID:
2844893

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