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Items: 1 to 50 of 159

1.

Identification of widespread antibiotic exposure in cholera patients correlates with clinically relevant microbiota changes.

Alexandrova L, Haque F, Rodriguez P, Marrazzo AC, Grembi JA, Ramachandran V, Hryckowian AJ, Adams CM, Siddique MSA, Khan AI, Qadri F, Andrews JR, Rahman M, Spormann AM, Schoolnik GK, Chien A, Nelson EJ.

J Infect Dis. 2019 Jun 13. pii: jiz299. doi: 10.1093/infdis/jiz299. [Epub ahead of print]

PMID:
31192364
2.

Multiplex Solid-Phase Melt Curve Analysis for the Point-of-Care Detection of HIV-1 Drug Resistance.

Clutter DS, Mazarei G, Sinha R, Manasa J, Nouhin J, LaPrade E, Bolouki S, Tzou PL, Hannita-Hui J, Sahoo MK, Kuimelis P, Kuimelis RG, Pinsky BA, Schoolnik GK, Hassibi A, Shafer RW.

J Mol Diagn. 2019 Jul;21(4):580-592. doi: 10.1016/j.jmoldx.2019.02.005. Epub 2019 Apr 23.

PMID:
31026601
3.

New Genome-Wide Algorithm Identifies Novel In-Vivo Expressed Mycobacterium Tuberculosis Antigens Inducing Human T-Cell Responses with Classical and Unconventional Cytokine Profiles.

Coppola M, van Meijgaarden KE, Franken KL, Commandeur S, Dolganov G, Kramnik I, Schoolnik GK, Comas I, Lund O, Prins C, van den Eeden SJ, Korsvold GE, Oftung F, Geluk A, Ottenhoff TH.

Sci Rep. 2016 Nov 28;6:37793. doi: 10.1038/srep37793.

4.

Sputum is a surrogate for bronchoalveolar lavage for monitoring Mycobacterium tuberculosis transcriptional profiles in TB patients.

Garcia BJ, Loxton AG, Dolganov GM, Van TT, Davis JL, de Jong BC, Voskuil MI, Leach SM, Schoolnik GK, Walzl G, Strong M, Walter ND.

Tuberculosis (Edinb). 2016 Sep;100:89-94. doi: 10.1016/j.tube.2016.07.004. Epub 2016 Jul 25.

5.

Adaptation of Mycobacterium tuberculosis to Impaired Host Immunity in HIV-Infected Patients.

Walter ND, de Jong BC, Garcia BJ, Dolganov GM, Worodria W, Byanyima P, Musisi E, Huang L, Chan ED, Van TT, Antonio M, Ayorinde A, Kato-Maeda M, Nahid P, Leung AM, Yen A, Fingerlin TE, Kechris K, Strong M, Voskuil MI, Davis JL, Schoolnik GK.

J Infect Dis. 2016 Oct 15;214(8):1205-11. doi: 10.1093/infdis/jiw364. Epub 2016 Aug 17. Erratum in: J Infect Dis. 2017 Feb 1;215(3):495.

6.

Transcriptional Adaptation of Drug-tolerant Mycobacterium tuberculosis During Treatment of Human Tuberculosis.

Walter ND, Dolganov GM, Garcia BJ, Worodria W, Andama A, Musisi E, Ayakaka I, Van TT, Voskuil MI, de Jong BC, Davidson RM, Fingerlin TE, Kechris K, Palmer C, Nahid P, Daley CL, Geraci M, Huang L, Cattamanchi A, Strong M, Schoolnik GK, Davis JL.

J Infect Dis. 2015 Sep 15;212(6):990-8. doi: 10.1093/infdis/jiv149. Epub 2015 Mar 11.

7.

Comprehensive insights into transcriptional adaptation of intracellular mycobacteria by microbe-enriched dual RNA sequencing.

Rienksma RA, Suarez-Diez M, Mollenkopf HJ, Dolganov GM, Dorhoi A, Schoolnik GK, Martins Dos Santos VA, Kaufmann SH, Schaap PJ, Gengenbacher M.

BMC Genomics. 2015 Feb 5;16:34. doi: 10.1186/s12864-014-1197-2.

8.

A minimum variance method for genome-wide data-driven normalization of quantitative real-time polymerase chain reaction expression data.

Garcia B, Walter ND, Dolganov G, Coram M, Davis JL, Schoolnik GK, Strong M.

Anal Biochem. 2014 Aug 1;458:11-3. doi: 10.1016/j.ab.2014.04.021. Epub 2014 Apr 26.

9.

Tuberculosis vaccine with high predicted population coverage and compatibility with modern diagnostics.

Knudsen NP, Nørskov-Lauritsen S, Dolganov GM, Schoolnik GK, Lindenstrøm T, Andersen P, Agger EM, Aagaard C.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1096-101. doi: 10.1073/pnas.1314973111. Epub 2014 Jan 6.

10.

ESAT-6 (EsxA) and TB10.4 (EsxH) based vaccines for pre- and post-exposure tuberculosis vaccination.

Hoang T, Aagaard C, Dietrich J, Cassidy JP, Dolganov G, Schoolnik GK, Lundberg CV, Agger EM, Andersen P.

PLoS One. 2013 Dec 12;8(12):e80579. doi: 10.1371/journal.pone.0080579. eCollection 2013.

11.

The Mycobacterium tuberculosis regulatory network and hypoxia.

Galagan JE, Minch K, Peterson M, Lyubetskaya A, Azizi E, Sweet L, Gomes A, Rustad T, Dolganov G, Glotova I, Abeel T, Mahwinney C, Kennedy AD, Allard R, Brabant W, Krueger A, Jaini S, Honda B, Yu WH, Hickey MJ, Zucker J, Garay C, Weiner B, Sisk P, Stolte C, Winkler JK, Van de Peer Y, Iazzetti P, Camacho D, Dreyfuss J, Liu Y, Dorhoi A, Mollenkopf HJ, Drogaris P, Lamontagne J, Zhou Y, Piquenot J, Park ST, Raman S, Kaufmann SH, Mohney RP, Chelsky D, Moody DB, Sherman DR, Schoolnik GK.

Nature. 2013 Jul 11;499(7457):178-83. doi: 10.1038/nature12337. Epub 2013 Jul 3.

12.

An unbiased genome-wide Mycobacterium tuberculosis gene expression approach to discover antigens targeted by human T cells expressed during pulmonary infection.

Commandeur S, van Meijgaarden KE, Prins C, Pichugin AV, Dijkman K, van den Eeden SJ, Friggen AH, Franken KL, Dolganov G, Kramnik I, Schoolnik GK, Oftung F, Korsvold GE, Geluk A, Ottenhoff TH.

J Immunol. 2013 Feb 15;190(4):1659-71. doi: 10.4049/jimmunol.1201593. Epub 2013 Jan 14.

13.

Chaperone activity of small heat shock proteins underlies therapeutic efficacy in experimental autoimmune encephalomyelitis.

Kurnellas MP, Brownell SE, Su L, Malkovskiy AV, Rajadas J, Dolganov G, Chopra S, Schoolnik GK, Sobel RA, Webster J, Ousman SS, Becker RA, Steinman L, Rothbard JB.

J Biol Chem. 2012 Oct 19;287(43):36423-34. doi: 10.1074/jbc.M112.371229. Epub 2012 Sep 6.

14.

Comparative analysis of Mycobacterium and related Actinomycetes yields insight into the evolution of Mycobacterium tuberculosis pathogenesis.

McGuire AM, Weiner B, Park ST, Wapinski I, Raman S, Dolganov G, Peterson M, Riley R, Zucker J, Abeel T, White J, Sisk P, Stolte C, Koehrsen M, Yamamoto RT, Iacobelli-Martinez M, Kidd MJ, Maer AM, Schoolnik GK, Regev A, Galagan J.

BMC Genomics. 2012 Mar 28;13:120. doi: 10.1186/1471-2164-13-120.

15.

The response of mycobacterium tuberculosis to reactive oxygen and nitrogen species.

Voskuil MI, Bartek IL, Visconti K, Schoolnik GK.

Front Microbiol. 2011 May 13;2:105. doi: 10.3389/fmicb.2011.00105. eCollection 2011.

16.

A multistage tuberculosis vaccine that confers efficient protection before and after exposure.

Aagaard C, Hoang T, Dietrich J, Cardona PJ, Izzo A, Dolganov G, Schoolnik GK, Cassidy JP, Billeskov R, Andersen P.

Nat Med. 2011 Feb;17(2):189-94. doi: 10.1038/nm.2285. Epub 2011 Jan 23.

PMID:
21258338
17.

A bistable switch and anatomical site control Vibrio cholerae virulence gene expression in the intestine.

Nielsen AT, Dolganov NA, Rasmussen T, Otto G, Miller MC, Felt SA, Torreilles S, Schoolnik GK.

PLoS Pathog. 2010 Sep 16;6(9):e1001102. doi: 10.1371/journal.ppat.1001102.

18.

TB database 2010: overview and update.

Galagan JE, Sisk P, Stolte C, Weiner B, Koehrsen M, Wymore F, Reddy TB, Zucker JD, Engels R, Gellesch M, Hubble J, Jin H, Larson L, Mao M, Nitzberg M, White J, Zachariah ZK, Sherlock G, Ball CA, Schoolnik GK.

Tuberculosis (Edinb). 2010 Jul;90(4):225-35. doi: 10.1016/j.tube.2010.03.010. Epub 2010 May 20. Review.

PMID:
20488753
19.

DosR-regulon genes induction in Mycobacterium bovis BCG under aerobic conditions.

Flores Valdez MA, Schoolnik GK.

Tuberculosis (Edinb). 2010 May;90(3):197-200. doi: 10.1016/j.tube.2010.04.001. Epub 2010 Apr 24.

20.

Bacterial genetic signatures of human social phenomena among M. tuberculosis from an Aboriginal Canadian population.

Pepperell C, Hoeppner VH, Lipatov M, Wobeser W, Schoolnik GK, Feldman MW.

Mol Biol Evol. 2010 Feb;27(2):427-40. doi: 10.1093/molbev/msp261. Epub 2009 Oct 27.

21.

Cross-reactive immunity to Mycobacterium tuberculosis DosR regulon-encoded antigens in individuals infected with environmental, nontuberculous mycobacteria.

Lin MY, Reddy TB, Arend SM, Friggen AH, Franken KL, van Meijgaarden KE, Verduyn MJ, Schoolnik GK, Klein MR, Ottenhoff TH.

Infect Immun. 2009 Nov;77(11):5071-9. doi: 10.1128/IAI.00457-09. Epub 2009 Sep 8.

22.

Mycobacterium tuberculosis modulates its cell surface via an oligopeptide permease (Opp) transport system.

Flores-Valdez MA, Morris RP, Laval F, Daffé M, Schoolnik GK.

FASEB J. 2009 Dec;23(12):4091-104. doi: 10.1096/fj.09-132407. Epub 2009 Aug 11.

23.

The Mycobacterium tuberculosis sigma factor sigmaB is required for full response to cell envelope stress and hypoxia in vitro, but it is dispensable for in vivo growth.

Fontán PA, Voskuil MI, Gomez M, Tan D, Pardini M, Manganelli R, Fattorini L, Schoolnik GK, Smith I.

J Bacteriol. 2009 Sep;191(18):5628-33. doi: 10.1128/JB.00510-09. Epub 2009 Jul 10.

24.

The DosR regulon of M. tuberculosis and antibacterial tolerance.

Bartek IL, Rutherford R, Gruppo V, Morton RA, Morris RP, Klein MR, Visconti KC, Ryan GJ, Schoolnik GK, Lenaerts A, Voskuil MI.

Tuberculosis (Edinb). 2009 Jul;89(4):310-6. doi: 10.1016/j.tube.2009.06.001. Epub 2009 Jul 3.

25.

TB database: an integrated platform for tuberculosis research.

Reddy TB, Riley R, Wymore F, Montgomery P, DeCaprio D, Engels R, Gellesch M, Hubble J, Jen D, Jin H, Koehrsen M, Larson L, Mao M, Nitzberg M, Sisk P, Stolte C, Weiner B, White J, Zachariah ZK, Sherlock G, Galagan JE, Ball CA, Schoolnik GK.

Nucleic Acids Res. 2009 Jan;37(Database issue):D499-508. doi: 10.1093/nar/gkn652. Epub 2008 Oct 3.

26.

The extracellular nuclease Dns and its role in natural transformation of Vibrio cholerae.

Blokesch M, Schoolnik GK.

J Bacteriol. 2008 Nov;190(21):7232-40. doi: 10.1128/JB.00959-08. Epub 2008 Aug 29.

27.

vpsA- and luxO-independent biofilms of Vibrio cholerae.

Müller J, Miller MC, Nielsen AT, Schoolnik GK, Spormann AM.

FEMS Microbiol Lett. 2007 Oct;275(2):199-206. Epub 2007 Aug 14.

28.

Serogroup conversion of Vibrio cholerae in aquatic reservoirs.

Blokesch M, Schoolnik GK.

PLoS Pathog. 2007 Jun;3(6):e81.

29.

Genomic and phenotypic diversity of coastal Vibrio cholerae strains is linked to environmental factors.

Keymer DP, Miller MC, Schoolnik GK, Boehm AB.

Appl Environ Microbiol. 2007 Jun;73(11):3705-14. Epub 2007 Apr 20.

30.

Detection and transformation of genome segments that differ within a coastal population of Vibrio cholerae strains.

Miller MC, Keymer DP, Avelar A, Boehm AB, Schoolnik GK.

Appl Environ Microbiol. 2007 Jun;73(11):3695-704. Epub 2007 Apr 20.

31.

Biofilm acts as a microenvironment for plankton-associated Vibrio cholerae in the aquatic environment of Bangladesh.

Islam MS, Jahid MI, Rahman MM, Rahman MZ, Islam MS, Kabir MS, Sack DA, Schoolnik GK.

Microbiol Immunol. 2007;51(4):369-79.

32.

RpoS controls the Vibrio cholerae mucosal escape response.

Nielsen AT, Dolganov NA, Otto G, Miller MC, Wu CY, Schoolnik GK.

PLoS Pathog. 2006 Oct;2(10):e109.

33.

Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis.

Leyten EM, Lin MY, Franken KL, Friggen AH, Prins C, van Meijgaarden KE, Voskuil MI, Weldingh K, Andersen P, Schoolnik GK, Arend SM, Ottenhoff TH, Klein MR.

Microbes Infect. 2006 Jul;8(8):2052-60. Epub 2006 Jun 13.

PMID:
16931093
34.

The competitive cost of antibiotic resistance in Mycobacterium tuberculosis.

Gagneux S, Long CD, Small PM, Van T, Schoolnik GK, Bohannan BJ.

Science. 2006 Jun 30;312(5782):1944-6.

35.

Evidence supporting predicted metabolic pathways for Vibrio cholerae: gene expression data and clinical tests.

Shi J, Romero PR, Schoolnik GK, Spormann AM, Karp PD.

Nucleic Acids Res. 2006 May 8;34(8):2438-44. Print 2006.

36.

Expression profiling of host pathogen interactions: how Mycobacterium tuberculosis and the macrophage adapt to one another.

Schnappinger D, Schoolnik GK, Ehrt S.

Microbes Infect. 2006 Apr;8(4):1132-40. Epub 2006 Jan 19. Review.

PMID:
16517202
38.

Chitin induces natural competence in Vibrio cholerae.

Meibom KL, Blokesch M, Dolganov NA, Wu CY, Schoolnik GK.

Science. 2005 Dec 16;310(5755):1824-7.

39.

Molecular analysis of rugosity in a Vibrio cholerae O1 El Tor phase variant.

Yildiz FH, Liu XS, Heydorn A, Schoolnik GK.

Mol Microbiol. 2004 Jul;53(2):497-515.

40.

Regulation of the Mycobacterium tuberculosis PE/PPE genes.

Voskuil MI, Schnappinger D, Rutherford R, Liu Y, Schoolnik GK.

Tuberculosis (Edinb). 2004;84(3-4):256-62.

PMID:
15207495
41.

Mycobacterium tuberculosis gene expression during adaptation to stationary phase and low-oxygen dormancy.

Voskuil MI, Visconti KC, Schoolnik GK.

Tuberculosis (Edinb). 2004;84(3-4):218-27.

PMID:
15207491
42.

Phage offer a real alternative.

Schoolnik GK, Summers WC, Watson JD.

Nat Biotechnol. 2004 May;22(5):505-6; author reply 506-7. No abstract available.

PMID:
15122279
43.

The Vibrio cholerae chitin utilization program.

Meibom KL, Li XB, Nielsen AT, Wu CY, Roseman S, Schoolnik GK.

Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2524-9.

44.
45.

Inhibition of HIV infectivity by a natural human isolate of Lactobacillus jensenii engineered to express functional two-domain CD4.

Chang TL, Chang CH, Simpson DA, Xu Q, Martin PK, Lagenaur LA, Schoolnik GK, Ho DD, Hillier SL, Holodniy M, Lewicki JA, Lee PP.

Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11672-7. Epub 2003 Sep 12.

46.

Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis dormancy program.

Voskuil MI, Schnappinger D, Visconti KC, Harrell MI, Dolganov GM, Sherman DR, Schoolnik GK.

J Exp Med. 2003 Sep 1;198(5):705-13.

47.

Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment.

Schnappinger D, Ehrt S, Voskuil MI, Liu Y, Mangan JA, Monahan IM, Dolganov G, Efron B, Butcher PD, Nathan C, Schoolnik GK.

J Exp Med. 2003 Sep 1;198(5):693-704.

48.

Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis.

Park HD, Guinn KM, Harrell MI, Liao R, Voskuil MI, Tompa M, Schoolnik GK, Sherman DR.

Mol Microbiol. 2003 May;48(3):833-43.

49.

Microarray expression profiling: capturing a genome-wide portrait of the transcriptome.

Conway T, Schoolnik GK.

Mol Microbiol. 2003 Feb;47(4):879-89. Review.

50.

Role of the extracytoplasmic-function sigma factor sigma(H) in Mycobacterium tuberculosis global gene expression.

Manganelli R, Voskuil MI, Schoolnik GK, Dubnau E, Gomez M, Smith I.

Mol Microbiol. 2002 Jul;45(2):365-74.

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