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Items: 1 to 50 of 200

1.

Identification of Widespread Antibiotic Exposure in Patients With Cholera Correlates With Clinically Relevant Microbiota Changes.

Alexandrova L, Haque F, Rodriguez P, Marrazzo AC, Grembi JA, Ramachandran V, Hryckowian AJ, Adams CM, Siddique MSA, Khan AI, Qadri F, Andrews JR, Rahman M, Spormann AM, Schoolnik GK, Chien A, Nelson EJ.

J Infect Dis. 2019 Oct 8;220(10):1655-1666. doi: 10.1093/infdis/jiz299.

2.

Multiplex Solid-Phase Melt Curve Analysis for the Point-of-Care Detection of HIV-1 Drug Resistance.

Clutter DS, Mazarei G, Sinha R, Manasa J, Nouhin J, LaPrade E, Bolouki S, Tzou PL, Hannita-Hui J, Sahoo MK, Kuimelis P, Kuimelis RG, Pinsky BA, Schoolnik GK, Hassibi A, Shafer RW.

J Mol Diagn. 2019 Jul;21(4):580-592. doi: 10.1016/j.jmoldx.2019.02.005. Epub 2019 Apr 23.

PMID:
31026601
3.

Multiplexed identification, quantification and genotyping of infectious agents using a semiconductor biochip.

Hassibi A, Manickam A, Singh R, Bolouki S, Sinha R, Jirage KB, McDermott MW, Hassibi B, Vikalo H, Mazarei G, Pei L, Bousse L, Miller M, Heshami M, Savage MP, Taylor MT, Gamini N, Wood N, Mantina P, Grogan P, Kuimelis P, Savalia P, Conradson S, Li Y, Meyer RB, Ku E, Ebert J, Pinsky BA, Dolganov G, Van T, Johnson KA, Naraghi-Arani P, Kuimelis RG, Schoolnik G.

Nat Biotechnol. 2018 Sep;36(8):738-745. doi: 10.1038/nbt.4179. Epub 2018 Jul 16.

PMID:
30010676
4.

Does discovery of differentially culturable M tuberculosis really demand a new treatment paradigm? Longitudinal analysis of DNA clearance from sputum.

Walter ND, Moore CM, Kayigire XA, Dide-Agossou C, Worodria W, Huang L, Everett CK, Schoolnik GS, Nahid P, Davis JL.

BMC Infect Dis. 2018 Jul 3;18(1):293. doi: 10.1186/s12879-018-3213-7.

5.

Corrigendum: Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure.

Malherbe ST, Shenai S, Ronacher K, Loxton AG, Dolganov G, Kriel M, Van T, Chen RY, Warwick J, Via LE, Song T, Lee M, Schoolnik G, Tromp G, Alland D, Barry CE 3rd, Winter J, Walzl G; Catalysis TB–Biomarker Consortium.

Nat Med. 2017 Dec 7;23(12):1499. doi: 10.1038/nm1217-1499a.

6.

A Fully Integrated CMOS Fluorescence Biochip for DNA and RNA Testing.

Manickam A, Singh R, McDermott M, Wood N, Bolouki S, Naraghi-Arani P, Johnson K, Kuimelis RG, Schoolnik G, Hassibi A.

IEEE J Solid-State Circuits. 2017 Nov;52(11):2857-2870. doi: 10.1109/JSSC.2017.2754363. Epub 2017 Oct 24.

7.

Significant under expression of the DosR regulon in M. tuberculosis complex lineage 6 in sputum.

Ofori-Anyinam B, Dolganov G, Van T, Davis JL, Walter ND, Garcia BJ, Voskuil M, Fissette K, Diels M, Driesen M, Meehan CJ, Yeboah-Manu D, Coscolla M, Gagneux S, Antonio M, Schoolnik G, Gehre F, de Jong BC.

Tuberculosis (Edinb). 2017 May;104:58-64. doi: 10.1016/j.tube.2017.03.001. Epub 2017 Mar 4.

8.

Corrigendum: Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure.

Malherbe ST, Shenai S, Ronacher K, Loxton AG, Dolganov G, Kriel M, Van T, Chen RY, Warwick J, Via LE, Song T, Lee M, Schoolnik G, Tromp G, Alland D, Barry CE 3rd, Winter J, Walzl G; Catalysis TB–Biomarker Consortium.

Nat Med. 2017 Apr 7;23(4):526. doi: 10.1038/nm0417-526a. No abstract available.

PMID:
28388609
9.

New Genome-Wide Algorithm Identifies Novel In-Vivo Expressed Mycobacterium Tuberculosis Antigens Inducing Human T-Cell Responses with Classical and Unconventional Cytokine Profiles.

Coppola M, van Meijgaarden KE, Franken KL, Commandeur S, Dolganov G, Kramnik I, Schoolnik GK, Comas I, Lund O, Prins C, van den Eeden SJ, Korsvold GE, Oftung F, Geluk A, Ottenhoff TH.

Sci Rep. 2016 Nov 28;6:37793. doi: 10.1038/srep37793.

10.

Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure.

Malherbe ST, Shenai S, Ronacher K, Loxton AG, Dolganov G, Kriel M, Van T, Chen RY, Warwick J, Via LE, Song T, Lee M, Schoolnik G, Tromp G, Alland D, Barry CE 3rd, Winter J, Walzl G; Catalysis TB–Biomarker Consortium, Lucas L, Spuy GV, Stanley K, Thiart L, Smith B, Du Plessis N, Beltran CG, Maasdorp E, Ellmann A, Choi H, Joh J, Dodd LE, Allwood B, Koegelenberg C, Vorster M, Griffith-Richards S.

Nat Med. 2016 Oct;22(10):1094-1100. doi: 10.1038/nm.4177. Epub 2016 Sep 5. Erratum in: Nat Med. 2017 Apr 7;23 (4):526. Nat Med. 2017 Dec 7;23 (12 ):1499.

11.

Sputum is a surrogate for bronchoalveolar lavage for monitoring Mycobacterium tuberculosis transcriptional profiles in TB patients.

Garcia BJ, Loxton AG, Dolganov GM, Van TT, Davis JL, de Jong BC, Voskuil MI, Leach SM, Schoolnik GK, Walzl G, Strong M, Walter ND.

Tuberculosis (Edinb). 2016 Sep;100:89-94. doi: 10.1016/j.tube.2016.07.004. Epub 2016 Jul 25.

12.

Adaptation of Mycobacterium tuberculosis to Impaired Host Immunity in HIV-Infected Patients.

Walter ND, de Jong BC, Garcia BJ, Dolganov GM, Worodria W, Byanyima P, Musisi E, Huang L, Chan ED, Van TT, Antonio M, Ayorinde A, Kato-Maeda M, Nahid P, Leung AM, Yen A, Fingerlin TE, Kechris K, Strong M, Voskuil MI, Davis JL, Schoolnik GK.

J Infect Dis. 2016 Oct 15;214(8):1205-11. doi: 10.1093/infdis/jiw364. Epub 2016 Aug 17. Erratum in: J Infect Dis. 2017 Feb 1;215(3):495.

13.

Impact of the Mycobaterium africanum West Africa 2 Lineage on TB Diagnostics in West Africa: Decreased Sensitivity of Rapid Identification Tests in The Gambia.

Ofori-Anyinam B, Kanuteh F, Agbla SC, Adetifa I, Okoi C, Dolganov G, Schoolnik G, Secka O, Antonio M, de Jong BC, Gehre F.

PLoS Negl Trop Dis. 2016 Jul 7;10(7):e0004801. doi: 10.1371/journal.pntd.0004801. eCollection 2016 Jul.

14.

Transcriptional Adaptation of Drug-tolerant Mycobacterium tuberculosis During Treatment of Human Tuberculosis.

Walter ND, Dolganov GM, Garcia BJ, Worodria W, Andama A, Musisi E, Ayakaka I, Van TT, Voskuil MI, de Jong BC, Davidson RM, Fingerlin TE, Kechris K, Palmer C, Nahid P, Daley CL, Geraci M, Huang L, Cattamanchi A, Strong M, Schoolnik GK, Davis JL.

J Infect Dis. 2015 Sep 15;212(6):990-8. doi: 10.1093/infdis/jiv149. Epub 2015 Mar 11.

15.

Comprehensive insights into transcriptional adaptation of intracellular mycobacteria by microbe-enriched dual RNA sequencing.

Rienksma RA, Suarez-Diez M, Mollenkopf HJ, Dolganov GM, Dorhoi A, Schoolnik GK, Martins Dos Santos VA, Kaufmann SH, Schaap PJ, Gengenbacher M.

BMC Genomics. 2015 Feb 5;16:34. doi: 10.1186/s12864-014-1197-2.

16.

A minimum variance method for genome-wide data-driven normalization of quantitative real-time polymerase chain reaction expression data.

Garcia B, Walter ND, Dolganov G, Coram M, Davis JL, Schoolnik GK, Strong M.

Anal Biochem. 2014 Aug 1;458:11-3. doi: 10.1016/j.ab.2014.04.021. Epub 2014 Apr 26.

17.

Transcription Factor Binding Site Mapping Using ChIP-Seq.

Jaini S, Lyubetskaya A, Gomes A, Peterson M, Tae Park S, Raman S, Schoolnik G, Galagan J.

Microbiol Spectr. 2014 Apr;2(2). doi: 10.1128/microbiolspec.MGM2-0035-2013. Review.

PMID:
26105820
18.

Tuberculosis vaccine with high predicted population coverage and compatibility with modern diagnostics.

Knudsen NP, Nørskov-Lauritsen S, Dolganov GM, Schoolnik GK, Lindenstrøm T, Andersen P, Agger EM, Aagaard C.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1096-101. doi: 10.1073/pnas.1314973111. Epub 2014 Jan 6.

19.

ESAT-6 (EsxA) and TB10.4 (EsxH) based vaccines for pre- and post-exposure tuberculosis vaccination.

Hoang T, Aagaard C, Dietrich J, Cassidy JP, Dolganov G, Schoolnik GK, Lundberg CV, Agger EM, Andersen P.

PLoS One. 2013 Dec 12;8(12):e80579. doi: 10.1371/journal.pone.0080579. eCollection 2013.

20.

The Mycobacterium tuberculosis regulatory network and hypoxia.

Galagan JE, Minch K, Peterson M, Lyubetskaya A, Azizi E, Sweet L, Gomes A, Rustad T, Dolganov G, Glotova I, Abeel T, Mahwinney C, Kennedy AD, Allard R, Brabant W, Krueger A, Jaini S, Honda B, Yu WH, Hickey MJ, Zucker J, Garay C, Weiner B, Sisk P, Stolte C, Winkler JK, Van de Peer Y, Iazzetti P, Camacho D, Dreyfuss J, Liu Y, Dorhoi A, Mollenkopf HJ, Drogaris P, Lamontagne J, Zhou Y, Piquenot J, Park ST, Raman S, Kaufmann SH, Mohney RP, Chelsky D, Moody DB, Sherman DR, Schoolnik GK.

Nature. 2013 Jul 11;499(7457):178-83. doi: 10.1038/nature12337. Epub 2013 Jul 3.

21.

An unbiased genome-wide Mycobacterium tuberculosis gene expression approach to discover antigens targeted by human T cells expressed during pulmonary infection.

Commandeur S, van Meijgaarden KE, Prins C, Pichugin AV, Dijkman K, van den Eeden SJ, Friggen AH, Franken KL, Dolganov G, Kramnik I, Schoolnik GK, Oftung F, Korsvold GE, Geluk A, Ottenhoff TH.

J Immunol. 2013 Feb 15;190(4):1659-71. doi: 10.4049/jimmunol.1201593. Epub 2013 Jan 14.

22.

Chaperone activity of small heat shock proteins underlies therapeutic efficacy in experimental autoimmune encephalomyelitis.

Kurnellas MP, Brownell SE, Su L, Malkovskiy AV, Rajadas J, Dolganov G, Chopra S, Schoolnik GK, Sobel RA, Webster J, Ousman SS, Becker RA, Steinman L, Rothbard JB.

J Biol Chem. 2012 Oct 19;287(43):36423-34. doi: 10.1074/jbc.M112.371229. Epub 2012 Sep 6.

23.

Comparative analysis of Mycobacterium and related Actinomycetes yields insight into the evolution of Mycobacterium tuberculosis pathogenesis.

McGuire AM, Weiner B, Park ST, Wapinski I, Raman S, Dolganov G, Peterson M, Riley R, Zucker J, Abeel T, White J, Sisk P, Stolte C, Koehrsen M, Yamamoto RT, Iacobelli-Martinez M, Kidd MJ, Maer AM, Schoolnik GK, Regev A, Galagan J.

BMC Genomics. 2012 Mar 28;13:120. doi: 10.1186/1471-2164-13-120.

24.

The response of mycobacterium tuberculosis to reactive oxygen and nitrogen species.

Voskuil MI, Bartek IL, Visconti K, Schoolnik GK.

Front Microbiol. 2011 May 13;2:105. doi: 10.3389/fmicb.2011.00105. eCollection 2011.

25.

A systems biology approach to infectious disease research: innovating the pathogen-host research paradigm.

Aderem A, Adkins JN, Ansong C, Galagan J, Kaiser S, Korth MJ, Law GL, McDermott JG, Proll SC, Rosenberger C, Schoolnik G, Katze MG.

mBio. 2011 Mar 1;2(1):e00325-10. doi: 10.1128/mBio.00325-10.

26.

A multistage tuberculosis vaccine that confers efficient protection before and after exposure.

Aagaard C, Hoang T, Dietrich J, Cardona PJ, Izzo A, Dolganov G, Schoolnik GK, Cassidy JP, Billeskov R, Andersen P.

Nat Med. 2011 Feb;17(2):189-94. doi: 10.1038/nm.2285. Epub 2011 Jan 23.

PMID:
21258338
27.

Tuberculosis in North Korea.

Perry S, Linton H, Schoolnik G.

Science. 2011 Jan 21;331(6015):263. doi: 10.1126/science.1201892. No abstract available.

28.

A bistable switch and anatomical site control Vibrio cholerae virulence gene expression in the intestine.

Nielsen AT, Dolganov NA, Rasmussen T, Otto G, Miller MC, Felt SA, Torreilles S, Schoolnik GK.

PLoS Pathog. 2010 Sep 16;6(9):e1001102. doi: 10.1371/journal.ppat.1001102.

29.

TB database 2010: overview and update.

Galagan JE, Sisk P, Stolte C, Weiner B, Koehrsen M, Wymore F, Reddy TB, Zucker JD, Engels R, Gellesch M, Hubble J, Jin H, Larson L, Mao M, Nitzberg M, White J, Zachariah ZK, Sherlock G, Ball CA, Schoolnik GK.

Tuberculosis (Edinb). 2010 Jul;90(4):225-35. doi: 10.1016/j.tube.2010.03.010. Epub 2010 May 20. Review.

PMID:
20488753
30.

DosR-regulon genes induction in Mycobacterium bovis BCG under aerobic conditions.

Flores Valdez MA, Schoolnik GK.

Tuberculosis (Edinb). 2010 May;90(3):197-200. doi: 10.1016/j.tube.2010.04.001. Epub 2010 Apr 24.

31.

Bacterial genetic signatures of human social phenomena among M. tuberculosis from an Aboriginal Canadian population.

Pepperell C, Hoeppner VH, Lipatov M, Wobeser W, Schoolnik GK, Feldman MW.

Mol Biol Evol. 2010 Feb;27(2):427-40. doi: 10.1093/molbev/msp261. Epub 2009 Oct 27.

32.

Cross-reactive immunity to Mycobacterium tuberculosis DosR regulon-encoded antigens in individuals infected with environmental, nontuberculous mycobacteria.

Lin MY, Reddy TB, Arend SM, Friggen AH, Franken KL, van Meijgaarden KE, Verduyn MJ, Schoolnik GK, Klein MR, Ottenhoff TH.

Infect Immun. 2009 Nov;77(11):5071-9. doi: 10.1128/IAI.00457-09. Epub 2009 Sep 8.

33.

Mycobacterium tuberculosis modulates its cell surface via an oligopeptide permease (Opp) transport system.

Flores-Valdez MA, Morris RP, Laval F, Daffé M, Schoolnik GK.

FASEB J. 2009 Dec;23(12):4091-104. doi: 10.1096/fj.09-132407. Epub 2009 Aug 11.

34.

The Mycobacterium tuberculosis sigma factor sigmaB is required for full response to cell envelope stress and hypoxia in vitro, but it is dispensable for in vivo growth.

Fontán PA, Voskuil MI, Gomez M, Tan D, Pardini M, Manganelli R, Fattorini L, Schoolnik GK, Smith I.

J Bacteriol. 2009 Sep;191(18):5628-33. doi: 10.1128/JB.00510-09. Epub 2009 Jul 10.

35.

The DosR regulon of M. tuberculosis and antibacterial tolerance.

Bartek IL, Rutherford R, Gruppo V, Morton RA, Morris RP, Klein MR, Visconti KC, Ryan GJ, Schoolnik GK, Lenaerts A, Voskuil MI.

Tuberculosis (Edinb). 2009 Jul;89(4):310-6. doi: 10.1016/j.tube.2009.06.001. Epub 2009 Jul 3.

36.

Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa.

Black GF, Thiel BA, Ota MO, Parida SK, Adegbola R, Boom WH, Dockrell HM, Franken KL, Friggen AH, Hill PC, Klein MR, Lalor MK, Mayanja H, Schoolnik G, Stanley K, Weldingh K, Kaufmann SH, Walzl G, Ottenhoff TH; GCGH Biomarkers for TB Consortium.

Clin Vaccine Immunol. 2009 Aug;16(8):1203-12. doi: 10.1128/CVI.00111-09. Epub 2009 Jun 24.

37.

Virulence, immunopathology and transmissibility of selected strains of Mycobacterium tuberculosis in a murine model.

Marquina-Castillo B, García-García L, Ponce-de-León A, Jimenez-Corona ME, Bobadilla-Del Valle M, Cano-Arellano B, Canizales-Quintero S, Martinez-Gamboa A, Kato-Maeda M, Robertson B, Young D, Small P, Schoolnik G, Sifuentes-Osornio J, Hernandez-Pando R.

Immunology. 2009 Sep;128(1):123-33. doi: 10.1111/j.1365-2567.2008.03004.x. Epub 2008 Dec 22.

38.

Role of melanin pigment in expression of Vibrio cholerae virulence factors.

Valeru SP, Rompikuntal PK, Ishikawa T, Vaitkevicius K, Sjöling A, Dolganov N, Zhu J, Schoolnik G, Wai SN.

Infect Immun. 2009 Mar;77(3):935-42. doi: 10.1128/IAI.00929-08. Epub 2008 Dec 22.

39.

TB database: an integrated platform for tuberculosis research.

Reddy TB, Riley R, Wymore F, Montgomery P, DeCaprio D, Engels R, Gellesch M, Hubble J, Jen D, Jin H, Koehrsen M, Larson L, Mao M, Nitzberg M, Sisk P, Stolte C, Weiner B, White J, Zachariah ZK, Sherlock G, Galagan JE, Ball CA, Schoolnik GK.

Nucleic Acids Res. 2009 Jan;37(Database issue):D499-508. doi: 10.1093/nar/gkn652. Epub 2008 Oct 3.

40.

The extracellular nuclease Dns and its role in natural transformation of Vibrio cholerae.

Blokesch M, Schoolnik GK.

J Bacteriol. 2008 Nov;190(21):7232-40. doi: 10.1128/JB.00959-08. Epub 2008 Aug 29.

41.

vpsA- and luxO-independent biofilms of Vibrio cholerae.

Müller J, Miller MC, Nielsen AT, Schoolnik GK, Spormann AM.

FEMS Microbiol Lett. 2007 Oct;275(2):199-206. Epub 2007 Aug 14.

42.

Serogroup conversion of Vibrio cholerae in aquatic reservoirs.

Blokesch M, Schoolnik GK.

PLoS Pathog. 2007 Jun;3(6):e81.

43.

Genomic and phenotypic diversity of coastal Vibrio cholerae strains is linked to environmental factors.

Keymer DP, Miller MC, Schoolnik GK, Boehm AB.

Appl Environ Microbiol. 2007 Jun;73(11):3705-14. Epub 2007 Apr 20.

44.

Detection and transformation of genome segments that differ within a coastal population of Vibrio cholerae strains.

Miller MC, Keymer DP, Avelar A, Boehm AB, Schoolnik GK.

Appl Environ Microbiol. 2007 Jun;73(11):3695-704. Epub 2007 Apr 20.

45.

Biofilm acts as a microenvironment for plankton-associated Vibrio cholerae in the aquatic environment of Bangladesh.

Islam MS, Jahid MI, Rahman MM, Rahman MZ, Islam MS, Kabir MS, Sack DA, Schoolnik GK.

Microbiol Immunol. 2007;51(4):369-79.

46.

RpoS controls the Vibrio cholerae mucosal escape response.

Nielsen AT, Dolganov NA, Otto G, Miller MC, Wu CY, Schoolnik GK.

PLoS Pathog. 2006 Oct;2(10):e109.

47.

Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis.

Leyten EM, Lin MY, Franken KL, Friggen AH, Prins C, van Meijgaarden KE, Voskuil MI, Weldingh K, Andersen P, Schoolnik GK, Arend SM, Ottenhoff TH, Klein MR.

Microbes Infect. 2006 Jul;8(8):2052-60. Epub 2006 Jun 13.

PMID:
16931093
48.

The competitive cost of antibiotic resistance in Mycobacterium tuberculosis.

Gagneux S, Long CD, Small PM, Van T, Schoolnik GK, Bohannan BJ.

Science. 2006 Jun 30;312(5782):1944-6.

49.

Evidence supporting predicted metabolic pathways for Vibrio cholerae: gene expression data and clinical tests.

Shi J, Romero PR, Schoolnik GK, Spormann AM, Karp PD.

Nucleic Acids Res. 2006 May 8;34(8):2438-44. Print 2006.

50.

Expression profiling of host pathogen interactions: how Mycobacterium tuberculosis and the macrophage adapt to one another.

Schnappinger D, Schoolnik GK, Ehrt S.

Microbes Infect. 2006 Apr;8(4):1132-40. Epub 2006 Jan 19. Review.

PMID:
16517202

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