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Items: 1 to 50 of 234

1.

Incidence of germline BRCA1/2 mutations in women with tubo-ovarian high-grade serous carcinomas with and without serous tubal intra-epithelial carcinomas.

Dowson CB, Stewart C, O'Sullivan S, Pachter N, Schofield L, Cohen PA.

Int J Gynecol Cancer. 2019 Nov 7. pii: ijgc-2019-000540. doi: 10.1136/ijgc-2019-000540. [Epub ahead of print]

PMID:
31699802
2.

Performance of emergency surgical front of neck airway access by head and neck surgeons, general surgeons, or anaesthetists: an in situ simulation study.

Groom P, Schofield L, Hettiarachchi N, Pickard S, Brown J, Sandars J, Morton B.

Br J Anaesth. 2019 Nov;123(5):696-703. doi: 10.1016/j.bja.2019.07.011. Epub 2019 Aug 23.

PMID:
31451190
3.

Vaccine-Induced Carbohydrate-Specific Memory B Cells Reactivate During Rodent Malaria Infection.

Joseph H, Tan QY, Mazhari R, Eriksson EM, Schofield L.

Front Immunol. 2019 Aug 9;10:1840. doi: 10.3389/fimmu.2019.01840. eCollection 2019.

4.

Enabling Global Clinical Collaborations on Identifiable Patient Data: The Minerva Initiative.

Nellåker C, Alkuraya FS, Baynam G, Bernier RA, Bernier FPJ, Boulanger V, Brudno M, Brunner HG, Clayton-Smith J, Cogné B, Dawkins HJS, deVries BBA, Douzgou S, Dudding-Byth T, Eichler EE, Ferlaino M, Fieggen K, Firth HV, FitzPatrick DR, Gration D, Groza T, Haendel M, Hallowell N, Hamosh A, Hehir-Kwa J, Hitz MP, Hughes M, Kini U, Kleefstra T, Kooy RF, Krawitz P, Küry S, Lees M, Lyon GJ, Lyonnet S, Marcadier JL, Meyn S, Moslerová V, Politei JM, Poulton CC, Raymond FL, Reijnders MRF, Robinson PN, Romano C, Rose CM, Sainsbury DCG, Schofield L, Sutton VR, Turnovec M, Van Dijck A, Van Esch H, Wilkie AOM; Minerva Consortium.

Front Genet. 2019 Jul 29;10:611. doi: 10.3389/fgene.2019.00611. eCollection 2019.

5.

'It has a lot more to contribute than just the teaching': Perceptions of participants in a peer-observation programme to develop clinical teaching.

Schofield L, Page M.

Future Healthc J. 2019 Mar;6(Suppl 1):170. doi: 10.7861/futurehosp.6-1-s170. No abstract available.

6.

Uptake of testing for germline BRCA mutations in patients with non-mucinous epithelial ovarian cancers in Western Australia: a comparison of different genetic counseling methods.

Stearnes G, Nichols CB, Schofield L, O'Sullivan S, Pachter N, Cohen PA.

Int J Gynecol Cancer. 2019 Jul;29(6):1038-1042. doi: 10.1136/ijgc-2019-000389. Epub 2019 May 17.

PMID:
31101686
7.

Early suppression of B cell immune responses by low doses of chloroquine and pyrimethamine: implications for studying immunity in malaria.

Joseph H, Eriksson E, Schofield L.

Parasitol Res. 2019 Jun;118(6):1987-1992. doi: 10.1007/s00436-019-06335-5. Epub 2019 May 8.

8.

Does ethnic diversity explain intra-UK variation in mortality? A longitudinal cohort study.

Schofield L, Walsh D, Feng Z, Buchanan D, Dibben C, Fischbacher C, McCartney G, Munoz-Arroyo R, Whyte B.

BMJ Open. 2019 Mar 30;9(3):e024563. doi: 10.1136/bmjopen-2018-024563.

9.

Inhibition of Rumen Methanogens by a Novel Archaeal Lytic Enzyme Displayed on Tailored Bionanoparticles.

Altermann E, Schofield LR, Ronimus RS, Beatty AK, Reilly K.

Front Microbiol. 2018 Oct 9;9:2378. doi: 10.3389/fmicb.2018.02378. eCollection 2018. Erratum in: Front Microbiol. 2018 Nov 22;9:2982.

10.

Structural determination of archaeal UDP-N-acetylglucosamine 4-epimerase from Methanobrevibacter ruminantium M1 in complex with the bacterial cell wall intermediate UDP-N-acetylmuramic acid.

Carbone V, Schofield LR, Sang C, Sutherland-Smith AJ, Ronimus RS.

Proteins. 2018 Dec;86(12):1306-1312. doi: 10.1002/prot.25606. Epub 2018 Oct 5.

PMID:
30242905
11.

Investigation of interactions between TLR2, MyD88 and TIRAP by bioluminescence resonance energy transfer is hampered by artefacts of protein overexpression.

Sampaio NG, Kocan M, Schofield L, Pfleger KDG, Eriksson EM.

PLoS One. 2018 Aug 23;13(8):e0202408. doi: 10.1371/journal.pone.0202408. eCollection 2018.

12.

A bioreactor system for the manufacture of a genetically modified Plasmodium falciparum blood stage malaria cell bank for use in a clinical trial.

Pawliw R, Farrow R, Sekuloski S, Jennings H, Healer J, Phuong T, Sathe P, Pasay C, Evans K, Cowman AF, Schofield L, Chen N, McCarthy J, Trenholme K.

Malar J. 2018 Aug 6;17(1):283. doi: 10.1186/s12936-018-2435-x.

13.

Treatment retention on fingolimod compared with injectable multiple sclerosis therapies in African-American patients: A subgroup analysis of a randomized phase 4 study.

Cascione M, Tenenbaum N, Wendt J, Meng X, Schofield L, Cree BAC; PREFERMS investigators.

Mult Scler Relat Disord. 2018 Oct;25:50-56. doi: 10.1016/j.msard.2018.07.014. Epub 2018 Jul 11.

14.

Death within 1 year among emergency medical admissions to Scottish hospitals: incident cohort study.

Moore E, Munoz-Arroyo R, Schofield L, Radley A, Clark D, Isles C.

BMJ Open. 2018 Jun 30;8(6):e021432. doi: 10.1136/bmjopen-2017-021432.

15.

Phase IV study of retention on fingolimod versus injectable multiple sclerosis therapies: a randomized clinical trial.

Cree BAC, Arnold DL, Cascione M, Fox EJ, Williams IM, Meng X, Schofield L, Tenenbaum N.

Ther Adv Neurol Disord. 2018 May 20;11:1756286418774338. doi: 10.1177/1756286418774338. eCollection 2018.

16.

Imaging Lung Function Abnormalities in Primary Ciliary Dyskinesia Using Hyperpolarized Gas Ventilation MRI.

Smith LJ, West N, Hughes D, Marshall H, Johns CS, Stewart NJ, Chan HF, Rao M, Capener DJ, Bray J, Collier GJ, Hughes PJC, Norquay G, Schofield L, Chetcuti P, Moya E, Wild JM.

Ann Am Thorac Soc. 2018 Dec;15(12):1487-1490. doi: 10.1513/AnnalsATS.201711-890RL. No abstract available.

17.

Spectral and spatial information from a novel dual-wavelength full-waveform terrestrial laser scanner for forest ecology.

Mark Danson F, Sasse F, Schofield LA.

Interface Focus. 2018 Apr 6;8(2):20170049. doi: 10.1098/rsfs.2017.0049. Epub 2018 Feb 16.

18.

Non-intersecting leaf insertion algorithm for tree structure models.

Åkerblom M, Raumonen P, Casella E, Disney MI, Danson FM, Gaulton R, Schofield LA, Kaasalainen M.

Interface Focus. 2018 Apr 6;8(2):20170045. doi: 10.1098/rsfs.2017.0045. Epub 2018 Feb 16.

19.

Extracellular vesicles from early stage Plasmodium falciparum-infected red blood cells contain PfEMP1 and induce transcriptional changes in human monocytes.

Sampaio NG, Emery SJ, Garnham AL, Tan QY, Sisquella X, Pimentel MA, Jex AR, Regev-Rudzki N, Schofield L, Eriksson EM.

Cell Microbiol. 2018 May;20(5):e12822. doi: 10.1111/cmi.12822. Epub 2018 Feb 15.

PMID:
29349926
20.

Investigating barriers to genetic counseling and germline mutation testing in women with suspected hereditary breast and ovarian cancer syndrome and Lynch syndrome.

Shaw J, Bulsara C, Cohen PA, Gryta M, Nichols CB, Schofield L, O'Sullivan S, Pachter N, Hardcastle SJ.

Patient Educ Couns. 2018 May;101(5):938-944. doi: 10.1016/j.pec.2017.12.011. Epub 2017 Dec 12.

PMID:
29273311
21.

Expression, Purification, and Characterization of (R)-Sulfolactate Dehydrogenase (ComC) from the Rumen Methanogen Methanobrevibacter millerae SM9.

Zhang Y, Schofield LR, Sang C, Dey D, Ronimus RS.

Archaea. 2017 Nov 6;2017:5793620. doi: 10.1155/2017/5793620. eCollection 2017.

22.

Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors.

Sisquella X, Ofir-Birin Y, Pimentel MA, Cheng L, Abou Karam P, Sampaio NG, Penington JS, Connolly D, Giladi T, Scicluna BJ, Sharples RA, Waltmann A, Avni D, Schwartz E, Schofield L, Porat Z, Hansen DS, Papenfuss AT, Eriksson EM, Gerlic M, Hill AF, Bowie AG, Regev-Rudzki N.

Nat Commun. 2017 Dec 7;8(1):1985. doi: 10.1038/s41467-017-02083-1.

23.

Improved Diagnosis and Care for Rare Diseases through Implementation of Precision Public Health Framework.

Baynam G, Bowman F, Lister K, Walker CE, Pachter N, Goldblatt J, Boycott KM, Gahl WA, Kosaki K, Adachi T, Ishii K, Mahede T, McKenzie F, Townshend S, Slee J, Kiraly-Borri C, Vasudevan A, Hawkins A, Broley S, Schofield L, Verhoef H, Groza T, Zankl A, Robinson PN, Haendel M, Brudno M, Mattick JS, Dinger ME, Roscioli T, Cowley MJ, Olry A, Hanauer M, Alkuraya FS, Taruscio D, Posada de la Paz M, Lochmüller H, Bushby K, Thompson R, Hedley V, Lasko P, Mina K, Beilby J, Tifft C, Davis M, Laing NG, Julkowska D, Le Cam Y, Terry SF, Kaufmann P, Eerola I, Norstedt I, Rath A, Suematsu M, Groft SC, Austin CP, Draghia-Akli R, Weeramanthri TS, Molster C, Dawkins HJS.

Adv Exp Med Biol. 2017;1031:55-94. doi: 10.1007/978-3-319-67144-4_4. Review.

PMID:
29214566
24.

The Methuselah Effect: The Pernicious Impact of Unreported Deaths on Old-Age Mortality Estimates.

Black DA, Hsu YC, Sanders SG, Schofield LS, Taylor LJ.

Demography. 2017 Dec;54(6):2001-2024. doi: 10.1007/s13524-017-0623-x.

25.

Plasmodium falciparum PfEMP1 Modulates Monocyte/Macrophage Transcription Factor Activation and Cytokine and Chemokine Responses.

Sampaio NG, Eriksson EM, Schofield L.

Infect Immun. 2017 Dec 19;86(1). pii: e00447-17. doi: 10.1128/IAI.00447-17. Print 2018 Jan.

26.

IgG antibodies to synthetic GPI are biomarkers of immune-status to both Plasmodium falciparum and Plasmodium vivax malaria in young children.

França CT, Li Wai Suen CSN, Carmagnac A, Lin E, Kiniboro B, Siba P, Schofield L, Mueller I.

Malar J. 2017 Sep 25;16(1):386. doi: 10.1186/s12936-017-2042-2.

27.

How do trends in mortality inequalities by deprivation and education in Scotland and England & Wales compare? A repeat cross-sectional study.

McCartney G, Popham F, Katikireddi SV, Walsh D, Schofield L.

BMJ Open. 2017 Jul 21;7(7):e017590. doi: 10.1136/bmjopen-2017-017590.

28.

IgG opsonization of merozoites: multiple immune mechanisms for malaria vaccine development.

Hill DL, Schofield L, Wilson DW.

Int J Parasitol. 2017 Sep;47(10-11):585-595. doi: 10.1016/j.ijpara.2017.05.004. Epub 2017 Jun 29. Review.

PMID:
28668325
29.

Synergistic effect of IL-12 and IL-18 induces TIM3 regulation of γδ T cell function and decreases the risk of clinical malaria in children living in Papua New Guinea.

Schofield L, Ioannidis LJ, Karl S, Robinson LJ, Tan QY, Poole DP, Betuela I, Hill DL, Siba PM, Hansen DS, Mueller I, Eriksson EM.

BMC Med. 2017 Jun 15;15(1):114. doi: 10.1186/s12916-017-0883-8.

30.

Development of Multiwell-Plate Methods Using Pure Cultures of Methanogens To Identify New Inhibitors for Suppressing Ruminant Methane Emissions.

Weimar MR, Cheung J, Dey D, McSweeney C, Morrison M, Kobayashi Y, Whitman WB, Carbone V, Schofield LR, Ronimus RS, Cook GM.

Appl Environ Microbiol. 2017 Jul 17;83(15). pii: e00396-17. doi: 10.1128/AEM.00396-17. Print 2017 Aug 1.

31.

Initiating an undiagnosed diseases program in the Western Australian public health system.

Baynam G, Broley S, Bauskis A, Pachter N, McKenzie F, Townshend S, Slee J, Kiraly-Borri C, Vasudevan A, Hawkins A, Schofield L, Helmholz P, Palmer R, Kung S, Walker CE, Molster C, Lewis B, Mina K, Beilby J, Pathak G, Poulton C, Groza T, Zankl A, Roscioli T, Dinger ME, Mattick JS, Gahl W, Groft S, Tifft C, Taruscio D, Lasko P, Kosaki K, Wilhelm H, Melegh B, Carapetis J, Jana S, Chaney G, Johns A, Owen PW, Daly F, Weeramanthri T, Dawkins H, Goldblatt J.

Orphanet J Rare Dis. 2017 May 3;12(1):83. doi: 10.1186/s13023-017-0619-z.

32.

3-Dimensional Facial Analysis-Facing Precision Public Health.

Baynam G, Bauskis A, Pachter N, Schofield L, Verhoef H, Palmer RL, Kung S, Helmholz P, Ridout M, Walker CE, Hawkins A, Goldblatt J, Weeramanthri TS, Dawkins HJS, Molster CM.

Front Public Health. 2017 Apr 10;5:31. doi: 10.3389/fpubh.2017.00031. eCollection 2017.

33.

Airway Clearance Techniques for Primary Ciliary Dyskinesia; is the Cystic Fibrosis literature portable?

Schofield LM, Duff A, Brennan C.

Paediatr Respir Rev. 2018 Jan;25:73-77. doi: 10.1016/j.prrv.2017.03.011. Epub 2017 Mar 16. Review.

34.

Anaemia in hospitalised preschool children from a rural area in Mozambique: a case control study in search for aetiological agents.

Moraleda C, Aguilar R, Quintó L, Nhampossa T, Renom M, Nhabomba A, Acácio S, Aponte JJ, Nhalungo D, Achtman AH, Schofield L, Martins H, Macete E, Alonso PL, Menéndez C.

BMC Pediatr. 2017 Feb 28;17(1):63. doi: 10.1186/s12887-017-0816-x.

35.

A novel method of standardized myocardial infarction in aged rabbits.

Morrissey PJ, Murphy KR, Daley JM, Schofield L, Turan NN, Arunachalam K, Abbott JD, Koren G.

Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H959-H967. doi: 10.1152/ajpheart.00582.2016. Epub 2017 Feb 17.

36.

Metabolomics-Based Elucidation of Active Metabolic Pathways in Erythrocytes and HSC-Derived Reticulocytes.

Srivastava A, Evans KJ, Sexton AE, Schofield L, Creek DJ.

J Proteome Res. 2017 Apr 7;16(4):1492-1505. doi: 10.1021/acs.jproteome.6b00902. Epub 2017 Mar 1.

PMID:
28166632
37.

The rare and undiagnosed diseases diagnostic service - application of massively parallel sequencing in a state-wide clinical service.

Baynam G, Pachter N, McKenzie F, Townshend S, Slee J, Kiraly-Borri C, Vasudevan A, Hawkins A, Broley S, Schofield L, Verhoef H, Walker CE, Molster C, Blackwell JM, Jamieson S, Tang D, Lassmann T, Mina K, Beilby J, Davis M, Laing N, Murphy L, Weeramanthri T, Dawkins H, Goldblatt J.

Orphanet J Rare Dis. 2016 Jun 11;11(1):77. doi: 10.1186/s13023-016-0462-7.

38.

A Retrospective Exploration of the Impact of the 'Angelina Jolie Effect' on the Single State-Wide Familial Cancer Program in Perth, Western Australia.

Freedman R, Mountain H, Karina D, Schofield L.

J Genet Couns. 2017 Feb;26(1):52-62. doi: 10.1007/s10897-016-9982-5. Epub 2016 Jun 6.

PMID:
27265404
39.

Likelihood of Death Within One Year Among a National Cohort of Hospital Inpatients in Scotland.

Clark D, Schofield L, Graham FM, Isles C, Gott M, Jarlbaek L.

J Pain Symptom Manage. 2016 Aug;52(2):e2-4. doi: 10.1016/j.jpainsymman.2016.05.007. Epub 2016 Jun 2. No abstract available.

40.

Dying younger in Scotland: Trends in mortality and deprivation relative to England and Wales, 1981-2011.

Schofield L, Walsh D, Munoz-Arroyo R, McCartney G, Buchanan D, Lawder R, Armstrong M, Dundas R, Leyland AH.

Health Place. 2016 Jul;40:106-15. doi: 10.1016/j.healthplace.2016.05.007. Epub 2016 May 25.

41.

Merozoite Antigens of Plasmodium falciparum Elicit Strain-Transcending Opsonizing Immunity.

Hill DL, Wilson DW, Sampaio NG, Eriksson EM, Ryg-Cornejo V, Harrison GLA, Uboldi AD, Robinson LJ, Beeson JG, Siba P, Cowman AF, Hansen DS, Mueller I, Schofield L.

Infect Immun. 2016 Jul 21;84(8):2175-2184. doi: 10.1128/IAI.00145-16. Print 2016 Aug.

42.

Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant.

Li J, Woods SL, Healey S, Beesley J, Chen X, Lee JS, Sivakumaran H, Wayte N, Nones K, Waterfall JJ, Pearson J, Patch AM, Senz J, Ferreira MA, Kaurah P, Mackenzie R, Heravi-Moussavi A, Hansford S, Lannagan TRM, Spurdle AB, Simpson PT, da Silva L, Lakhani SR, Clouston AD, Bettington M, Grimpen F, Busuttil RA, Di Costanzo N, Boussioutas A, Jeanjean M, Chong G, Fabre A, Olschwang S, Faulkner GJ, Bellos E, Coin L, Rioux K, Bathe OF, Wen X, Martin HC, Neklason DW, Davis SR, Walker RL, Calzone KA, Avital I, Heller T, Koh C, Pineda M, Rudloff U, Quezado M, Pichurin PN, Hulick PJ, Weissman SM, Newlin A, Rubinstein WS, Sampson JE, Hamman K, Goldgar D, Poplawski N, Phillips K, Schofield L, Armstrong J, Kiraly-Borri C, Suthers GK, Huntsman DG, Foulkes WD, Carneiro F, Lindor NM, Edwards SL, French JD, Waddell N, Meltzer PS, Worthley DL, Schrader KA, Chenevix-Trench G.

Am J Hum Genet. 2016 May 5;98(5):830-842. doi: 10.1016/j.ajhg.2016.03.001. Epub 2016 Apr 14.

43.

Impact of Clinical Genetics Attendance at a Gynecologic Oncology Tumor Board on Referrals for Genetic Counseling and BRCA Mutation Testing.

Cohen PA, Nichols CB, Schofield L, Van Der Werf S, Pachter N.

Int J Gynecol Cancer. 2016 Jun;26(5):892-7. doi: 10.1097/IGC.0000000000000689.

PMID:
27051053
44.

CORRECTING FOR MEASUREMENT ERROR IN LATENT VARIABLES USED AS PREDICTORS.

Schofield LS.

Ann Appl Stat. 2015 Dec 1;9(4):2133-2152.

45.

Brown Adipose Tissue Exhibits a Glucose-Responsive Thermogenic Biorhythm in Humans.

Lee P, Bova R, Schofield L, Bryant W, Dieckmann W, Slattery A, Govendir MA, Emmett L, Greenfield JR.

Cell Metab. 2016 Apr 12;23(4):602-9. doi: 10.1016/j.cmet.2016.02.007. Epub 2016 Mar 10.

46.

A Toll-like receptor-1 variant and its characteristic cellular phenotype is associated with severe malaria in Papua New Guinean children.

Manning L, Cutts J, Stanisic DI, Laman M, Carmagnac A, Allen S, O'Donnell A, Karunajeewa H, Rosanas-Urgell A, Siba P, Davis TM, Michon P, Schofield L, Rockett K, Kwiatkowski D, Mueller I.

Genes Immun. 2016 Jan-Feb;17(1):52-9. doi: 10.1038/gene.2015.50. Epub 2015 Dec 3.

47.

Fat, weather, and date affect migratory songbirds' departure decisions, routes, and time it takes to cross the Gulf of Mexico.

Deppe JL, Ward MP, Bolus RT, Diehl RH, Celis-Murillo A, Zenzal TJ Jr, Moore FR, Benson TJ, Smolinsky JA, Schofield LN, Enstrom DA, Paxton EH, Bohrer G, Beveroth TA, Raim A, Obringer RL, Delaney D, Cochran WW.

Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):E6331-8. doi: 10.1073/pnas.1503381112. Epub 2015 Nov 2.

48.

Strategies for understanding and reducing the Plasmodium vivax and Plasmodium ovale hypnozoite reservoir in Papua New Guinean children: a randomised placebo-controlled trial and mathematical model.

Robinson LJ, Wampfler R, Betuela I, Karl S, White MT, Li Wai Suen CS, Hofmann NE, Kinboro B, Waltmann A, Brewster J, Lorry L, Tarongka N, Samol L, Silkey M, Bassat Q, Siba PM, Schofield L, Felger I, Mueller I.

PLoS Med. 2015 Oct 27;12(10):e1001891. doi: 10.1371/journal.pmed.1001891. eCollection 2015 Oct.

49.

Biochemical Characterisation of Phage Pseudomurein Endoisopeptidases PeiW and PeiP Using Synthetic Peptides.

Schofield LR, Beattie AK, Tootill CM, Dey D, Ronimus RS.

Archaea. 2015 Sep 21;2015:828693. doi: 10.1155/2015/828693. eCollection 2015.

50.

First-dose effects of fingolimod after switching from injectable therapies in the randomized, open-label, multicenter, Evaluate Patient OutComes (EPOC) study in relapsing multiple sclerosis.

Hughes B, Cascione M, Freedman MS, Agius M, Kantor D, Gudesblatt M, Goldstick LP, Agashivala N, Schofield L, McCague K, Hashmonay R, Barbato L; EPOC study investigators.

Mult Scler Relat Disord. 2014 Sep;3(5):620-8. doi: 10.1016/j.msard.2014.06.006. Epub 2014 Jul 3.

PMID:
26265274

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