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Items: 21

1.

Synthesis of Sulfur-Containing Exo-Bicyclic Dienes and Their Diels-Alder Reactions To Access Thiacycle-Fused Polycyclic Systems.

Castanheiro T, Schoenfelder A, Donnard M, Chataigner I, Gulea M.

J Org Chem. 2018 Apr 20;83(8):4505-4515. doi: 10.1021/acs.joc.8b00213. Epub 2018 Apr 6.

PMID:
29613799
2.

Correlation between capillary oxygen saturation and small intestinal wall thickness in the equine colic patient.

Mirle E, Wogatzki A, Kunzmann R, Schoenfelder AM, Litzke LF.

Vet Rec Open. 2017 Apr 23;4(1):e000197. doi: 10.1136/vetreco-2016-000197. eCollection 2017.

3.

MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.

Hoch L, Faure H, Roudaut H, Schoenfelder A, Mann A, Girard N, Bihannic L, Ayrault O, Petricci E, Taddei M, Rognan D, Ruat M.

FASEB J. 2015 May;29(5):1817-29. doi: 10.1096/fj.14-267849. Epub 2015 Jan 30.

4.

Discovery, molecular and pharmacological characterization of GSA-10, a novel small-molecule positive modulator of Smoothened.

Gorojankina T, Hoch L, Faure H, Roudaut H, Traiffort E, Schoenfelder A, Girard N, Mann A, Manetti F, Solinas A, Petricci E, Taddei M, Ruat M.

Mol Pharmacol. 2013 May;83(5):1020-9. doi: 10.1124/mol.112.084590. Epub 2013 Feb 28. Erratum in: Mol Pharmacol. 2013 Aug;84(2):303.

PMID:
23448715
5.

Stereoselective multicomponent assembly of enantiopure oxazolopiperidines and -azepines.

Zill N, Schoenfelder A, Girard N, Taddei M, Mann A.

J Org Chem. 2012 Mar 2;77(5):2246-53. doi: 10.1021/jo202455c. Epub 2012 Feb 13.

PMID:
22283333
6.

Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity.

Solinas A, Faure H, Roudaut H, Traiffort E, Schoenfelder A, Mann A, Manetti F, Taddei M, Ruat M.

J Med Chem. 2012 Feb 23;55(4):1559-71. doi: 10.1021/jm2013369. Epub 2012 Feb 10.

PMID:
22268551
7.

Estimation of estradiol in mouse serum samples: evaluation of commercial estradiol immunoassays.

Haisenleder DJ, Schoenfelder AH, Marcinko ES, Geddis LM, Marshall JC.

Endocrinology. 2011 Nov;152(11):4443-7. doi: 10.1210/en.2011-1501. Epub 2011 Sep 20.

8.

Resource use efficiency and community effects of invasive Hypochaeris radicata (Asteraceae) during primary succession.

Schoenfelder AC, Bishop JG, Martinson HM, Fagan WF.

Am J Bot. 2010 Nov;97(11):1772-9. doi: 10.3732/ajb.0900383. Epub 2010 Oct 1.

9.

Identification and mechanism of action of the acylguanidine MRT-83, a novel potent Smoothened antagonist.

Roudaut H, Traiffort E, Gorojankina T, Vincent L, Faure H, Schoenfelder A, Mann A, Manetti F, Solinas A, Taddei M, Ruat M.

Mol Pharmacol. 2011 Mar;79(3):453-60. doi: 10.1124/mol.110.069708. Epub 2010 Dec 21.

PMID:
21177415
10.

Virtual screening-based discovery and mechanistic characterization of the acylthiourea MRT-10 family as smoothened antagonists.

Manetti F, Faure H, Roudaut H, Gorojankina T, Traiffort E, Schoenfelder A, Mann A, Solinas A, Taddei M, Ruat M.

Mol Pharmacol. 2010 Oct;78(4):658-65. doi: 10.1124/mol.110.065102. Epub 2010 Jul 27.

PMID:
20664000
11.

A general approach to aza-heterocycles by means of domino sequences driven by hydroformylation.

Airiau E, Spangenberg T, Girard N, Schoenfelder A, Salvadori J, Taddei M, Mann A.

Chemistry. 2008;14(35):10938-48. doi: 10.1002/chem.200801795.

PMID:
19009576
12.

Application of Rhodium-Catalyzed Cyclohydrocarbonylation to the Syntheses of Enantiopure Homokainoids.

Chiou WH, Schoenfelder A, Mann A, Ojima I.

Pure Appl Chem. 2008;80(5):1019-1024.

13.

Rhodium-catalyzed cyclohydrocarbonylation approach to the syntheses of enantiopure homokainoids.

Chiou WH, Schoenfelder A, Sun L, Mann A, Ojima I.

J Org Chem. 2007 Dec 7;72(25):9418-25. Epub 2007 Nov 14.

PMID:
17999516
14.

A new method for the synthesis of chiral beta-branched alpha-amino acids.

Spangenberg T, Schoenfelder A, Breit B, Mann A.

Org Lett. 2007 Sep 27;9(20):3881-4. Epub 2007 Sep 6.

PMID:
17803310
15.

Identification and characterization of Hedgehog modulator properties after functional coupling of Smoothened to G15.

Masdeu C, Faure H, Coulombe J, Schoenfelder A, Mann A, Brabet I, Pin JP, Traiffort E, Ruat M.

Biochem Biophys Res Commun. 2006 Oct 20;349(2):471-9. Epub 2006 Aug 22.

PMID:
16945339
16.

Microwaves make hydroformylation a rapid and easy process.

Petricci E, Mann A, Schoenfelder A, Rota A, Taddei M.

Org Lett. 2006 Aug 17;8(17):3725-7.

PMID:
16898802
17.

Potentiation of apple procyanidin-triggered apoptosis by the polyamine oxidase inactivator MDL 72527 in human colon cancer-derived metastatic cells.

Gossé F, Roussi S, Guyot S, Schoenfelder A, Mann A, Bergerat JP, Seiler N, Raul F.

Int J Oncol. 2006 Aug;29(2):423-8.

PMID:
16820885
18.

(2S,4S)-2-amino-4-(4,4-diphenylbut-1-yl)- pentane-1,5-dioic acid: a potent and selective antagonist for metabotropic glutamate receptors negatively linked to adenylate cyclase.

Wermuth CG, Mann A, Schoenfelder A, Wright RA, Johnson BG, Burnett JP, Mayne NG, Schoepp DD.

J Med Chem. 1996 Feb 16;39(4):814-6. No abstract available.

PMID:
8632404
19.

Nafadotride, a potent preferential dopamine D3 receptor antagonist, activates locomotion in rodents.

Sautel F, Griffon N, Sokoloff P, Schwartz JC, Launay C, Simon P, Costentin J, Schoenfelder A, Garrido F, Mann A, et al.

J Pharmacol Exp Ther. 1995 Dec;275(3):1239-46.

PMID:
8531087
20.

Analogues of gamma-hydroxybutyric acid. Synthesis and binding studies.

Bourguignon JJ, Schoenfelder A, Schmitt M, Wermuth CG, Hechler V, Charlier B, Maitre M.

J Med Chem. 1988 May;31(5):893-7.

PMID:
3361576
21.

Synthesis and structure-activity relationships of a series of aminopyridazine derivatives of gamma-aminobutyric acid acting as selective GABA-A antagonists.

Wermuth CG, Bourguignon JJ, Schlewer G, Gies JP, Schoenfelder A, Melikian A, Bouchet MJ, Chantreux D, Molimard JC, Heaulme M, et al.

J Med Chem. 1987 Feb;30(2):239-49.

PMID:
3027337

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