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Alive and Ventilator Free: A Hierarchical, Composite Outcome for Clinical Trials in the Acute Respiratory Distress Syndrome.

Novack V, Beitler JR, Yitshak-Sade M, Thompson BT, Schoenfeld DA, Rubenfeld G, Talmor D, Brown SM.

Crit Care Med. 2020 Feb;48(2):158-166. doi: 10.1097/CCM.0000000000004104.


Selection design phase II trial of high dosages of tamoxifen and creatine in amyotrophic lateral sclerosis.

Babu S, Macklin EA, Jackson KE, Simpson E, Mahoney K, Yu H, Walker J, Simmons Z, David WS, Barkhaus PE, Simionescu L, Dimachkie MM, Pestronk A, Salameh JS, Weiss MD, Brooks BR, Schoenfeld D, Shefner J, Aggarwal S, Cudkowicz ME, Atassi N.

Amyotroph Lateral Scler Frontotemporal Degener. 2019 Oct 14:1-9. doi: 10.1080/21678421.2019.1672750. [Epub ahead of print]


Derivation and validation of a machine learning record linkage algorithm between emergency medical services and the emergency department.

Redfield C, Tlimat A, Halpern Y, Schoenfeld DW, Ullman E, Sontag DA, Nathanson LA, Horng S.

J Am Med Inform Assoc. 2020 Jan 1;27(1):147-153. doi: 10.1093/jamia/ocz176.


Urinary 11-nor-9-carboxy-tetrahydrocannabinol elimination in adolescent and young adult cannabis users during one month of sustained and biochemically-verified abstinence.

Schuster RM, Potter K, Vandrey R, Hareli M, Gilman J, Schoenfeld D, Evins AE.

J Psychopharmacol. 2020 Feb;34(2):197-210. doi: 10.1177/0269881119872206. Epub 2019 Sep 19.


Design and analysis of a clinical trial using previous trials as historical control.

Schoenfeld DA, Finkelstein DM, Macklin E, Zach N, Ennist DL, Taylor AA, Atassi N; Pooled Resource Open-Access ALS Clinical Trials Consortium.

Clin Trials. 2019 Oct;16(5):531-538. doi: 10.1177/1740774519858914. Epub 2019 Jul 1.


A Randomized Placebo-Controlled Trial of Low-Dose Testosterone Therapy in Women With Anorexia Nervosa.

Kimball A, Schorr M, Meenaghan E, Bachmann KN, Eddy KT, Misra M, Lawson EA, Kreiger-Benson E, Herzog DB, Koman S, Keane RJ, Ebrahimi S, Schoenfeld D, Klibanski A, Miller KK.

J Clin Endocrinol Metab. 2019 Oct 1;104(10):4347-4355. doi: 10.1210/jc.2019-00828.


Assessing utility and completeness of information transmission during emergency department transfers.

Lewis JJ, Schoenfeld DW, Landry A.

Int J Emerg Med. 2018 Oct 29;11(1):44. doi: 10.1186/s12245-018-0203-x.


Reappraisal of Ventilator-Free Days in Critical Care Research.

Yehya N, Harhay MO, Curley MAQ, Schoenfeld DA, Reeder RW.

Am J Respir Crit Care Med. 2019 Oct 1;200(7):828-836. doi: 10.1164/rccm.201810-2050CP.


Disparities in care among patients presenting to the emergency department for urinary stone disease.

Schoenfeld D, Mohn L, Agalliu I, Stern JM.

Urolithiasis. 2019 Apr 25. doi: 10.1007/s00240-019-01136-y. [Epub ahead of print]


A New Mobile-responsive Solution to Increase Patient Adherence: Instant Personalized Product Handouts.

Song EH, Milne CT, Hamm T, Mize J, Lebendiskaya N, Robinson S, Ensz E, Schoenfeld DA, Whiston-Lemm K, Wong AK, Ferreira L.

Wounds. 2019 Apr;31(4):E21-E24. Review.


A commentary on: statistical inference problems in sequential parallel comparison designs.

Schoenfeld DA, Doros G, Fava M.

J Biopharm Stat. 2019;29(6):1130-1133. doi: 10.1080/10543406.2019.1584207. Epub 2019 Feb 22.


Fecal transplant modifies urine chemistry risk factors for urinary stone disease.

Stern JM, Urban-Maldonado M, Usyk M, Granja I, Schoenfeld D, Davies KP, Agalliu I, Asplin J, Burk R, Suadicani SO.

Physiol Rep. 2019 Feb;7(4):e14012. doi: 10.14814/phy2.14012.


Efficacy and Posttreatment Effects of Therapist-Delivered Cognitive Behavioral Therapy vs Supportive Psychotherapy for Adults With Body Dysmorphic Disorder: A Randomized Clinical Trial.

Wilhelm S, Phillips KA, Greenberg JL, O'Keefe SM, Hoeppner SS, Keshaviah A, Sarvode-Mothi S, Schoenfeld DA.

JAMA Psychiatry. 2019 Apr 1;76(4):363-373. doi: 10.1001/jamapsychiatry.2018.4156.


Cross-domain correlates of cannabis use disorder severity among young adults.

Schuster RM, Hareli M, Moser AD, Lowman K, Gilman J, Ulysse C, Schoenfeld D, Evins AE.

Addict Behav. 2019 Jun;93:212-218. doi: 10.1016/j.addbeh.2019.01.029. Epub 2019 Jan 23.


Baseline chronic kidney disease does not predict long-term renal functional decline after percutaneous nephrolithotomy.

Watts KL, Srivastava A, Lin W, Schoenfeld D, Abramowitz M, Stern JM.

Urolithiasis. 2019 Oct;47(5):449-453. doi: 10.1007/s00240-019-01113-5. Epub 2019 Feb 12.


Editorial: We may need large trials to find treatments for neurodegenerative diseases.

Schoenfeld DA, Benatar M.

Clin Trials. 2019 Apr;16(2):120-121. doi: 10.1177/1740774518820814. Epub 2019 Jan 10. No abstract available.


The Effect of Shared Decisionmaking on Patients' Likelihood of Filing a Complaint or Lawsuit: A Simulation Study.

Schoenfeld EM, Mader S, Houghton C, Wenger R, Probst MA, Schoenfeld DA, Lindenauer PK, Mazor KM.

Ann Emerg Med. 2019 Jul;74(1):126-136. doi: 10.1016/j.annemergmed.2018.11.017. Epub 2019 Jan 3.


Outcomes for Patients Undergoing Ambulatory Percutaneous Nephrolithotomy.

Schoenfeld D, Zhou T, Stern JM.

J Endourol. 2019 Mar;33(3):189-193. doi: 10.1089/end.2018.0579. Epub 2019 Jan 2.


A pilot trial of RNS60 in amyotrophic lateral sclerosis.

Paganoni S, Alshikho MJ, Luppino S, Chan J, Pothier L, Schoenfeld D, Andres PL, Babu S, Zürcher NR, Loggia ML, Barry RL, Luotti S, Nardo G, Trolese MC, Pantalone S, Bendotti C, Bonetto V, De Marchi F, Rosen B, Hooker J, Cudkowicz M, Atassi N.

Muscle Nerve. 2019 Mar;59(3):303-308. doi: 10.1002/mus.26385. Epub 2018 Dec 26.


Elevated fetal haemoglobin levels are associated with decreased incidence of retinopathy in adults with sickle cell disease.

Mian UK, Tang J, Allende APM, Heo M, Bernstein N, Vattappally L, Schoenfeld D, Minniti CP.

Br J Haematol. 2018 Dec;183(5):807-811. doi: 10.1111/bjh.15617. Epub 2018 Nov 12.


One Month of Cannabis Abstinence in Adolescents and Young Adults Is Associated With Improved Memory.

Schuster RM, Gilman J, Schoenfeld D, Evenden J, Hareli M, Ulysse C, Nip E, Hanly A, Zhang H, Evins AE.

J Clin Psychiatry. 2018 Oct 30;79(6). pii: 17m11977. doi: 10.4088/JCP.17m11977.


Prospective Assessment of the Feasibility of a Trial of Low-Tidal Volume Ventilation for Patients with Acute Respiratory Failure.

Lanspa MJ, Gong MN, Schoenfeld DA, Lee KT, Grissom CK, Hou PC, Serpa-Neto A, Brown SM, Iwashyna TJ, Yealy DM, Hough CL, Brower RG, Calfee CS, Hyzy RC, Matthay MA, Miller RR 3rd, Steingrub JS, Thompson BT, Miller CD, Clemmer TP, Hendey GW, Huang DT, Mathews KS, Qadir N, Tidswell M; The National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury (PETAL) Clinical Trials Network.

Ann Am Thorac Soc. 2019 Mar;16(3):356-362. doi: 10.1513/AnnalsATS.201807-459OC.


Estimation for an accelerated failure time model with intermediate states as auxiliary information.

Ramchandani R, Finkelstein DM, Schoenfeld DA.

Lifetime Data Anal. 2020 Jan;26(1):1-20. doi: 10.1007/s10985-018-9452-5. Epub 2018 Nov 1.


Graphing the Win Ratio and its components over time.

Finkelstein DM, Schoenfeld DA.

Stat Med. 2019 Jan 15;38(1):53-61. doi: 10.1002/sim.7895. Epub 2018 Sep 11.


Phase IIb Trial of an α7 Nicotinic Receptor Partial Agonist With and Without Nicotine Patch for Withdrawal-Associated Cognitive Deficits and Tobacco Abstinence.

Schuster RM, Pachas GN, Stoeckel L, Cather C, Nadal M, Mischoulon D, Schoenfeld DA, Zhang H, Ulysse C, Dodds EB, Sobolewski S, Hudziak V, Hanly A, Fava M, Evins AE.

J Clin Psychopharmacol. 2018 Aug;38(4):307-316. doi: 10.1097/JCP.0000000000000919.


Long-Term Evaluation of the Effects of Aclidinium Bromide on Major Adverse Cardiovascular Events and COPD Exacerbations in Patients with Moderate to Very Severe COPD: Rationale and Design of the ASCENT COPD Study.

Wise RA, Chapman KR, Scirica BM, Schoenfeld DA, Bhatt DL, Daoud SZ, Seoane B, Reisner C, Garcia Gil E.

Chronic Obstr Pulm Dis. 2018 Jan 24;5(1):5-15. doi: 10.15326/jcopdf.5.1.2017.0149.


Randomized, double-blind, placebo-controlled trial of arimoclomol in rapidly progressive SOD1 ALS.

Benatar M, Wuu J, Andersen PM, Atassi N, David W, Cudkowicz M, Schoenfeld D.

Neurology. 2018 Feb 13;90(7):e565-e574. doi: 10.1212/WNL.0000000000004960. Epub 2018 Jan 24.


An open label study of a novel immunosuppression intervention for the treatment of amyotrophic lateral sclerosis.

Fournier CN, Schoenfeld D, Berry JD, Cudkowicz ME, Chan J, Quinn C, Brown RH, Salameh JS, Tansey MG, Beers DR, Appel SH, Glass JD.

Amyotroph Lateral Scler Frontotemporal Degener. 2018 May;19(3-4):242-249. doi: 10.1080/21678421.2017.1421666. Epub 2018 Jan 8.


Informatively clustering longitudinal microarrays using binary or survival outcome data.

Hsu JJ, Finkelstein DM, Schoenfeld DA.

Commun Stat Case Stud Data Anal Appl. 2018;4(1):18-27. doi: 10.1080/23737484.2018.1455542. Epub 2018 Apr 9.


A randomized controlled trial of resistance and endurance exercise in amyotrophic lateral sclerosis.

Clawson LL, Cudkowicz M, Krivickas L, Brooks BR, Sanjak M, Allred P, Atassi N, Swartz A, Steinhorn G, Uchil A, Riley KM, Yu H, Schoenfeld DA, Maragakis NJ; neals consortium.

Amyotroph Lateral Scler Frontotemporal Degener. 2018 May;19(3-4):250-258. doi: 10.1080/21678421.2017.1404108. Epub 2017 Nov 30.


Causal inference methods to study gastric tube use in amyotrophic lateral sclerosis.

McDonnell E, Schoenfeld D, Paganoni S, Atassi N.

Neurology. 2017 Oct 3;89(14):1483-1489. doi: 10.1212/WNL.0000000000004534. Epub 2017 Sep 1.


Urate levels predict survival in amyotrophic lateral sclerosis: Analysis of the expanded Pooled Resource Open-Access ALS clinical trials database.

Paganoni S, Nicholson K, Chan J, Shui A, Schoenfeld D, Sherman A, Berry J, Cudkowicz M, Atassi N; Pooled Resource Open-Access ALS Clinical Trials Consortium.

Muscle Nerve. 2018 Mar;57(3):430-434. doi: 10.1002/mus.25950. Epub 2017 Sep 21.


Functional Decline is Associated with Hopelessness in Amyotrophic Lateral Sclerosis (ALS).

Paganoni S, McDonnell E, Schoenfeld D, Yu H, Deng J, Atassi H, Sherman A, Yerramilli-Rao P, Cudkowicz M, Atassi N.

J Neurol Neurophysiol. 2017 Apr;8(2). pii: 423. doi: 10.4172/2155-9562.1000423. Epub 2017 Apr 29.


Relationship between Race and the Effect of Fluids on Long-term Mortality after Acute Respiratory Distress Syndrome. Secondary Analysis of the National Heart, Lung, and Blood Institute Fluid and Catheter Treatment Trial.

Jolley SE, Hough CL, Clermont G, Hayden D, Hou S, Schoenfeld D, Smith NL, Thompson BT, Bernard GR, Angus DC; ARDS Network Investigators.

Ann Am Thorac Soc. 2017 Sep;14(9):1443-1449. doi: 10.1513/AnnalsATS.201611-906OC.


Longitudinal immunological characterization of the first presensitized recipient of a face transplant.

Win TS, Murakami N, Borges TJ, Chandraker A, Murphy G, Lian C, Barrera V, Ho Sui S, Schoenfeld D, Teague J, Bueno E, Tullius SG, Pomahac B, Clark RA, Riella LV.

JCI Insight. 2017 Jul 6;2(13). pii: 93894. doi: 10.1172/jci.insight.93894. eCollection 2017 Jul 6.


Comment on: Progression-Free Survival as a Surrogate for Overall Survival in Clinical Trials of Targeted Therapy in Advanced Solid Tumors.

Schoenfeld DA.

Drugs. 2017 Jul;77(10):1137-1138. doi: 10.1007/s40265-017-0760-y. No abstract available.


Nonlinear Imputation of PaO2/FIO2 From SpO2/FIO2 Among Mechanically Ventilated Patients in the ICU: A Prospective, Observational Study.

Brown SM, Duggal A, Hou PC, Tidswell M, Khan A, Exline M, Park PK, Schoenfeld DA, Liu M, Grissom CK, Moss M, Rice TW, Hough CL, Rivers E, Thompson BT, Brower RG; National Institutes of Health (NIH)/National Heart, Lung, and Blood Institute (NHLBI) Prevention and Early Treatment of Acute Lung Injury (PETAL) Network.

Crit Care Med. 2017 Aug;45(8):1317-1324. doi: 10.1097/CCM.0000000000002514.


Predictors of tobacco abstinence in outpatient smokers with schizophrenia or bipolar disorder treated with varenicline and cognitive behavioral smoking cessation therapy.

Schuster RM, Cather C, Pachas GN, Zhang H, Cieslak KM, Hoeppner SS, Schoenfeld D, Evins AE.

Addict Behav. 2017 Aug;71:89-95. doi: 10.1016/j.addbeh.2017.02.028. Epub 2017 Feb 24.


Erratum to: Enhanced Bulbar Function in Amyotrophic Lateral Sclerosis: The Nuedexta Treatment Trial.

Smith R, Pioro E, Myers K, Sirdofsky M, Goslin K, Meekins G, Yu H, Wymer J, Cudkowicz M, Macklin EA, Schoenfeld D, Pattee G.

Neurotherapeutics. 2017 Jul;14(3):830. doi: 10.1007/s13311-017-0517-z. No abstract available.


Interview Day Environment May Influence Applicant Selection of Emergency Medicine Residency Programs.

Lewis J, Dubosh N, Rosen C, Schoenfeld D, Fisher J, Ullman E.

West J Emerg Med. 2017 Jan;18(1):142-145. doi: 10.5811/westjem.2016.10.31245. Epub 2016 Nov 15.


Enhanced Bulbar Function in Amyotrophic Lateral Sclerosis: The Nuedexta Treatment Trial.

Smith R, Pioro E, Myers K, Sirdofsky M, Goslin K, Meekins G, Yu H, Wymer J, Cudkowicz M, Macklin EA, Schoenfeld D, Pattee G.

Neurotherapeutics. 2017 Jul;14(3):762-772. doi: 10.1007/s13311-016-0508-5. Erratum in: Neurotherapeutics. 2017 Mar 10;:.


Maintenance pharmacotherapy normalizes the relapse curve in recently abstinent tobacco smokers with schizophrenia and bipolar disorder.

Evins AE, Hoeppner SS, Schoenfeld DA, Hoeppner BB, Cather C, Pachas GN, Cieslak KM, Maravic MC.

Schizophr Res. 2017 May;183:124-129. doi: 10.1016/j.schres.2016.11.018. Epub 2016 Dec 9.


Power Calculations to Select Instruments for Clinical Trial Secondary Endpoints. A Case Study of Instrument Selection for Post-Traumatic Stress Symptoms in Subjects with Acute Respiratory Distress Syndrome.

Sjoding MW, Schoenfeld DA, Brown SM, Hough CL, Yealy DM, Moss M, Angus DC, Iwashyna TJ; NHLBI Prevention and Early Treatment of Acute Lung Injury (PETAL) Network.

Ann Am Thorac Soc. 2017 Jan;14(1):110-117. doi: 10.1513/AnnalsATS.201608-585OC.


Induced regulatory T cells in allograft tolerance via transient mixed chimerism.

Hotta K, Aoyama A, Oura T, Yamada Y, Tonsho M, Huh KH, Kawai K, Schoenfeld D, Allan JS, Madsen JC, Benichou G, Smith RN, Colvin RB, Sachs DH, Cosimi AB, Kawai T.

JCI Insight. 2016 Jul 7;1(10). pii: e86419.


Quantitative strength testing in ALS clinical trials.

Shefner JM, Liu D, Leitner ML, Schoenfeld D, Johns DR, Ferguson T, Cudkowicz M.

Neurology. 2016 Aug 9;87(6):617-24. doi: 10.1212/WNL.0000000000002941. Epub 2016 Jul 6.


Coronary CT Angiography Versus Standard Emergency Department Evaluation for Acute Chest Pain and Diabetic Patients: Is There Benefit With Early Coronary CT Angiography? Results of the Randomized Comparative Effectiveness ROMICAT II Trial.

Truong QA, Schulman-Marcus J, Zakroysky P, Chou ET, Nagurney JT, Fleg JL, Schoenfeld DA, Udelson JE, Hoffmann U, Woodard PK.

J Am Heart Assoc. 2016 Mar 22;5(3):e003137. doi: 10.1161/JAHA.115.003137.


Assessing survival benefit when treatment delays disease progression.

Schoenfeld DA, Finkelstein DM.

Clin Trials. 2016 Jun;13(3):352-7. doi: 10.1177/1740774515625990. Epub 2016 Feb 22.


Bipolar CHOICE (Clinical Health Outcomes Initiative in Comparative Effectiveness): a pragmatic 6-month trial of lithium versus quetiapine for bipolar disorder.

Nierenberg AA, McElroy SL, Friedman ES, Ketter TA, Shelton RC, Deckersbach T, McInnis MG, Bowden CL, Tohen M, Kocsis JH, Calabrese JR, Kinrys G, Bobo WV, Singh V, Kamali M, Kemp D, Brody B, Reilly-Harrington NA, Sylvia LG, Shesler LW, Bernstein EE, Schoenfeld D, Rabideau DJ, Leon AC, Faraone S, Thase ME.

J Clin Psychiatry. 2016 Jan;77(1):90-9. doi: 10.4088/JCP.14m09349.


Nonlinear Imputation of Pao2/Fio2 From Spo2/Fio2 Among Patients With Acute Respiratory Distress Syndrome.

Brown SM, Grissom CK, Moss M, Rice TW, Schoenfeld D, Hou PC, Thompson BT, Brower RG; NIH/NHLBI PETAL Network Collaborators.

Chest. 2016 Aug;150(2):307-13. doi: 10.1016/j.chest.2016.01.003. Epub 2016 Jan 19.


Global rank tests for multiple, possibly censored, outcomes.

Ramchandani R, Schoenfeld DA, Finkelstein DM.

Biometrics. 2016 Sep;72(3):926-35. doi: 10.1111/biom.12475. Epub 2016 Jan 26.

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