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Items: 19

1.

Epigenetic silencing of miR-296 and miR-512 ensures hTERT dependent apoptosis protection and telomere maintenance in basal-type breast cancer cells.

Dinami R, Buemi V, Sestito R, Zappone A, Ciani Y, Mano M, Petti E, Sacconi A, Blandino G, Giacca M, Piazza S, Benetti R, Schoeftner S.

Oncotarget. 2017 Sep 23;8(56):95674-95691. doi: 10.18632/oncotarget.21180. eCollection 2017 Nov 10.

2.

OCT4 controls mitotic stability and inactivates the RB tumor suppressor pathway to enhance ovarian cancer aggressiveness.

Comisso E, Scarola M, Rosso M, Piazza S, Marzinotto S, Ciani Y, Orsaria M, Mariuzzi L, Schneider C, Schoeftner S, Benetti R.

Oncogene. 2017 Jul 27;36(30):4253-4266. doi: 10.1038/onc.2017.20. Epub 2017 Mar 20.

PMID:
28319064
3.

Epigenetic silencing of Oct4 by a complex containing SUV39H1 and Oct4 pseudogene lncRNA.

Scarola M, Comisso E, Pascolo R, Chiaradia R, Marion RM, Schneider C, Blasco MA, Schoeftner S, Benetti R.

Nat Commun. 2015 Jul 9;6:7631. doi: 10.1038/ncomms8631.

4.

Altered telomere homeostasis and resistance to skin carcinogenesis in Suv39h1 transgenic mice.

Petti E, Jordi F, Buemi V, Dinami R, Benetti R, Blasco MA, Schoeftner S.

Cell Cycle. 2015;14(9):1438-46. doi: 10.1080/15384101.2015.1021517.

5.

Sox4 links tumor suppression to accelerated aging in mice by modulating stem cell activation.

Foronda M, Martínez P, Schoeftner S, Gómez-López G, Schneider R, Flores JM, Pisano DG, Blasco MA.

Cell Rep. 2014 Jul 24;8(2):487-500. doi: 10.1016/j.celrep.2014.06.031. Epub 2014 Jul 17.

6.

miR-155 drives telomere fragility in human breast cancer by targeting TRF1.

Dinami R, Ercolani C, Petti E, Piazza S, Ciani Y, Sestito R, Sacconi A, Biagioni F, le Sage C, Agami R, Benetti R, Mottolese M, Schneider C, Blandino G, Schoeftner S.

Cancer Res. 2014 Aug 1;74(15):4145-56. doi: 10.1158/0008-5472.CAN-13-2038. Epub 2014 May 29.

7.

An Oct4-pRb axis, controlled by MiR-335, integrates stem cell self-renewal and cell cycle control.

Schoeftner S, Scarola M, Comisso E, Schneider C, Benetti R.

Stem Cells. 2013 Apr;31(4):717-28. doi: 10.1002/stem.1315.

8.

miR-335 directly targets Rb1 (pRb/p105) in a proximal connection to p53-dependent stress response.

Scarola M, Schoeftner S, Schneider C, Benetti R.

Cancer Res. 2010 Sep 1;70(17):6925-33. doi: 10.1158/0008-5472.CAN-10-0141. Epub 2010 Aug 16.

9.

Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites.

Martinez P, Thanasoula M, Carlos AR, Gómez-López G, Tejera AM, Schoeftner S, Dominguez O, Pisano DG, Tarsounas M, Blasco MA.

Nat Cell Biol. 2010 Aug;12(8):768-80. doi: 10.1038/ncb2081. Epub 2010 Jul 11.

10.

Telomere shortening relaxes X chromosome inactivation and forces global transcriptome alterations.

Schoeftner S, Blanco R, Lopez de Silanes I, Muñoz P, Gómez-López G, Flores JM, Blasco MA.

Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19393-8. doi: 10.1073/pnas.0909265106. Epub 2009 Nov 3.

11.

Chromatin regulation and non-coding RNAs at mammalian telomeres.

Schoeftner S, Blasco MA.

Semin Cell Dev Biol. 2010 Apr;21(2):186-93. doi: 10.1016/j.semcdb.2009.09.015. Epub 2009 Oct 6. Review.

PMID:
19815087
12.

A 'higher order' of telomere regulation: telomere heterochromatin and telomeric RNAs.

Schoeftner S, Blasco MA.

EMBO J. 2009 Aug 19;28(16):2323-36. doi: 10.1038/emboj.2009.197. Epub 2009 Jul 23. Review.

13.

Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells.

Marion RM, Strati K, Li H, Tejera A, Schoeftner S, Ortega S, Serrano M, Blasco MA.

Cell Stem Cell. 2009 Feb 6;4(2):141-54. doi: 10.1016/j.stem.2008.12.010.

14.

TRF1 controls telomere length and mitotic fidelity in epithelial homeostasis.

Muñoz P, Blanco R, de Carcer G, Schoeftner S, Benetti R, Flores JM, Malumbres M, Blasco MA.

Mol Cell Biol. 2009 Mar;29(6):1608-25. doi: 10.1128/MCB.01339-08. Epub 2009 Jan 5.

15.

Role of TRF2 in the assembly of telomeric chromatin.

Benetti R, Schoeftner S, Muñoz P, Blasco MA.

Cell Cycle. 2008 Nov 1;7(21):3461-8. Epub 2008 Nov 12.

PMID:
18971622
16.

A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases.

Benetti R, Gonzalo S, Jaco I, Muñoz P, Gonzalez S, Schoeftner S, Murchison E, Andl T, Chen T, Klatt P, Li E, Serrano M, Millar S, Hannon G, Blasco MA.

Nat Struct Mol Biol. 2008 Sep;15(9):998. No abstract available.

PMID:
18769471
17.

A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases.

Benetti R, Gonzalo S, Jaco I, Muñoz P, Gonzalez S, Schoeftner S, Murchison E, Andl T, Chen T, Klatt P, Li E, Serrano M, Millar S, Hannon G, Blasco MA.

Nat Struct Mol Biol. 2008 Mar;15(3):268-79. doi: 10.1038/nsmb.1399. Epub 2008 Mar 2. Erratum in: Nat Struct Mol Biol. 2008 Sep;15(9):998.

18.

Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II.

Schoeftner S, Blasco MA.

Nat Cell Biol. 2008 Feb;10(2):228-36. Epub 2007 Dec 23.

PMID:
18157120
19.

Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing.

Schoeftner S, Sengupta AK, Kubicek S, Mechtler K, Spahn L, Koseki H, Jenuwein T, Wutz A.

EMBO J. 2006 Jul 12;25(13):3110-22. Epub 2006 Jun 8.

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