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Items: 31

1.

Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in β2AR-cAMP Responsiveness in Murine Hearts.

Wright PT, Bhogal NK, Diakonov I, Pannell LMK, Perera RK, Bork NI, Schobesberger S, Lucarelli C, Faggian G, Alvarez-Laviada A, Zaccolo M, Kamp TJ, Balijepalli RC, Lyon AR, Harding SE, Nikolaev VO, Gorelik J.

Cell Rep. 2018 Apr 10;23(2):459-469. doi: 10.1016/j.celrep.2018.03.053.

2.

In Vitro Negative Inotropic Effect of Low Concentrations of Bupivacaine Relates to Diminished Ca2+ Sensitivity but Not to Ca2+ Handling or β-Adrenoceptor Signaling.

Flenner F, Arlt N, Nasib M, Schobesberger S, Koch T, Ravens U, Friedrich F, Nikolaev V, Christ T, Stehr SN.

Anesthesiology. 2018 Jun;128(6):1175-1186. doi: 10.1097/ALN.0000000000002180.

PMID:
29547406
3.

Oxidant sensor in the cGMP-binding pocket of PKGIα regulates nitroxyl-mediated kinase activity.

Donzelli S, Goetz M, Schmidt K, Wolters M, Stathopoulou K, Diering S, Prysyazhna O, Polat V, Scotcher J, Dees C, Subramanian H, Butt E, Kamynina A, Schobesberger S, King SB, Nikolaev VO, de Wit C, Leichert LI, Feil R, Eaton P, Cuello F.

Sci Rep. 2017 Aug 30;7(1):9938. doi: 10.1038/s41598-017-09275-1.

4.

T-tubule remodelling disturbs localized β2-adrenergic signalling in rat ventricular myocytes during the progression of heart failure.

Schobesberger S, Wright P, Tokar S, Bhargava A, Mansfield C, Glukhov AV, Poulet C, Buzuk A, Monszpart A, Sikkel M, Harding SE, Nikolaev VO, Lyon AR, Gorelik J.

Cardiovasc Res. 2017 Jun 1;113(7):770-782. doi: 10.1093/cvr/cvx074.

5.

Isomerization of Second-Generation Isoprene Peroxy Radicals: Epoxide Formation and Implications for Secondary Organic Aerosol Yields.

D'Ambro EL, Møller KH, Lopez-Hilfiker FD, Schobesberger S, Liu J, Shilling JE, Lee BH, Kjaergaard HG, Thornton JA.

Environ Sci Technol. 2017 May 2;51(9):4978-4987. doi: 10.1021/acs.est.7b00460. Epub 2017 Apr 19.

PMID:
28388039
6.

Comparison of the SAWNUC model with CLOUD measurements of sulphuric acid-water nucleation.

Ehrhart S, Ickes L, Almeida J, Amorim A, Barmet P, Bianchi F, Dommen J, Dunne EM, Duplissy J, Franchin A, Kangasluoma J, Kirkby J, Kürten A, Kupc A, Lehtipalo K, Nieminen T, Riccobono F, Rondo L, Schobesberger S, Steiner G, Tomé A, Wimmer D, Baltensperger U, Wagner PE, Curtius J.

J Geophys Res Atmos. 2016 Oct 27;121(20):12401-12414. doi: 10.1002/2015JD023723.

7.

Global atmospheric particle formation from CERN CLOUD measurements.

Dunne EM, Gordon H, Kürten A, Almeida J, Duplissy J, Williamson C, Ortega IK, Pringle KJ, Adamov A, Baltensperger U, Barmet P, Benduhn F, Bianchi F, Breitenlechner M, Clarke A, Curtius J, Dommen J, Donahue NM, Ehrhart S, Flagan RC, Franchin A, Guida R, Hakala J, Hansel A, Heinritzi M, Jokinen T, Kangasluoma J, Kirkby J, Kulmala M, Kupc A, Lawler MJ, Lehtipalo K, Makhmutov V, Mann G, Mathot S, Merikanto J, Miettinen P, Nenes A, Onnela A, Rap A, Reddington CL, Riccobono F, Richards NA, Rissanen MP, Rondo L, Sarnela N, Schobesberger S, Sengupta K, Simon M, Sipilä M, Smith JN, Stozkhov Y, Tomé A, Tröstl J, Wagner PE, Wimmer D, Winkler PM, Worsnop DR, Carslaw KS.

Science. 2016 Dec 2;354(6316):1119-1124. Epub 2016 Oct 27.

8.

Reduced anthropogenic aerosol radiative forcing caused by biogenic new particle formation.

Gordon H, Sengupta K, Rap A, Duplissy J, Frege C, Williamson C, Heinritzi M, Simon M, Yan C, Almeida J, Tröstl J, Nieminen T, Ortega IK, Wagner R, Dunne EM, Adamov A, Amorim A, Bernhammer AK, Bianchi F, Breitenlechner M, Brilke S, Chen X, Craven JS, Dias A, Ehrhart S, Fischer L, Flagan RC, Franchin A, Fuchs C, Guida R, Hakala J, Hoyle CR, Jokinen T, Junninen H, Kangasluoma J, Kim J, Kirkby J, Krapf M, Kürten A, Laaksonen A, Lehtipalo K, Makhmutov V, Mathot S, Molteni U, Monks SA, Onnela A, Peräkylä O, Piel F, Petäjä T, Praplan AP, Pringle KJ, Richards NA, Rissanen MP, Rondo L, Sarnela N, Schobesberger S, Scott CE, Seinfeld JH, Sharma S, Sipilä M, Steiner G, Stozhkov Y, Stratmann F, Tomé A, Virtanen A, Vogel AL, Wagner AC, Wagner PE, Weingartner E, Wimmer D, Winkler PM, Ye P, Zhang X, Hansel A, Dommen J, Donahue NM, Worsnop DR, Baltensperger U, Kulmala M, Curtius J, Carslaw KS.

Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12053-12058. Epub 2016 Oct 10.

9.

Effect of dimethylamine on the gas phase sulfuric acid concentration measured by Chemical Ionization Mass Spectrometry.

Rondo L, Ehrhart S, Kürten A, Adamov A, Bianchi F, Breitenlechner M, Duplissy J, Franchin A, Dommen J, Donahue NM, Dunne EM, Flagan RC, Hakala J, Hansel A, Keskinen H, Kim J, Jokinen T, Lehtipalo K, Leiminger M, Praplan A, Riccobono F, Rissanen MP, Sarnela N, Schobesberger S, Simon M, Sipilä M, Smith JN, Tomé A, Tröstl J, Tsagkogeorgas G, Vaattovaara P, Winkler PM, Williamson C, Wimmer D, Baltensperger U, Kirkby J, Kulmala M, Petäjä T, Worsnop DR, Curtius J.

J Geophys Res Atmos. 2016 Mar 27;121(6):3036-3049. Epub 2016 Mar 24.

10.

Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure.

Sanchez-Alonso JL, Bhargava A, O'Hara T, Glukhov AV, Schobesberger S, Bhogal N, Sikkel MB, Mansfield C, Korchev YE, Lyon AR, Punjabi PP, Nikolaev VO, Trayanova NA, Gorelik J.

Circ Res. 2016 Sep 30;119(8):944-55. doi: 10.1161/CIRCRESAHA.116.308698. Epub 2016 Aug 29.

11.

The role of low-volatility organic compounds in initial particle growth in the atmosphere.

Tröstl J, Chuang WK, Gordon H, Heinritzi M, Yan C, Molteni U, Ahlm L, Frege C, Bianchi F, Wagner R, Simon M, Lehtipalo K, Williamson C, Craven JS, Duplissy J, Adamov A, Almeida J, Bernhammer AK, Breitenlechner M, Brilke S, Dias A, Ehrhart S, Flagan RC, Franchin A, Fuchs C, Guida R, Gysel M, Hansel A, Hoyle CR, Jokinen T, Junninen H, Kangasluoma J, Keskinen H, Kim J, Krapf M, Kürten A, Laaksonen A, Lawler M, Leiminger M, Mathot S, Möhler O, Nieminen T, Onnela A, Petäjä T, Piel FM, Miettinen P, Rissanen MP, Rondo L, Sarnela N, Schobesberger S, Sengupta K, Sipilä M, Smith JN, Steiner G, Tomè A, Virtanen A, Wagner AC, Weingartner E, Wimmer D, Winkler PM, Ye P, Carslaw KS, Curtius J, Dommen J, Kirkby J, Kulmala M, Riipinen I, Worsnop DR, Donahue NM, Baltensperger U.

Nature. 2016 May 26;533(7604):527-31. doi: 10.1038/nature18271.

12.

Ion-induced nucleation of pure biogenic particles.

Kirkby J, Duplissy J, Sengupta K, Frege C, Gordon H, Williamson C, Heinritzi M, Simon M, Yan C, Almeida J, Tröstl J, Nieminen T, Ortega IK, Wagner R, Adamov A, Amorim A, Bernhammer AK, Bianchi F, Breitenlechner M, Brilke S, Chen X, Craven J, Dias A, Ehrhart S, Flagan RC, Franchin A, Fuchs C, Guida R, Hakala J, Hoyle CR, Jokinen T, Junninen H, Kangasluoma J, Kim J, Krapf M, Kürten A, Laaksonen A, Lehtipalo K, Makhmutov V, Mathot S, Molteni U, Onnela A, Peräkylä O, Piel F, Petäjä T, Praplan AP, Pringle K, Rap A, Richards NA, Riipinen I, Rissanen MP, Rondo L, Sarnela N, Schobesberger S, Scott CE, Seinfeld JH, Sipilä M, Steiner G, Stozhkov Y, Stratmann F, Tomé A, Virtanen A, Vogel AL, Wagner AC, Wagner PE, Weingartner E, Wimmer D, Winkler PM, Ye P, Zhang X, Hansel A, Dommen J, Donahue NM, Worsnop DR, Baltensperger U, Kulmala M, Carslaw KS, Curtius J.

Nature. 2016 May 26;533(7604):521-6. doi: 10.1038/nature17953.

13.

The effect of acid-base clustering and ions on the growth of atmospheric nano-particles.

Lehtipalo K, Rondo L, Kontkanen J, Schobesberger S, Jokinen T, Sarnela N, Kürten A, Ehrhart S, Franchin A, Nieminen T, Riccobono F, Sipilä M, Yli-Juuti T, Duplissy J, Adamov A, Ahlm L, Almeida J, Amorim A, Bianchi F, Breitenlechner M, Dommen J, Downard AJ, Dunne EM, Flagan RC, Guida R, Hakala J, Hansel A, Jud W, Kangasluoma J, Kerminen VM, Keskinen H, Kim J, Kirkby J, Kupc A, Kupiainen-Määttä O, Laaksonen A, Lawler MJ, Leiminger M, Mathot S, Olenius T, Ortega IK, Onnela A, Petäjä T, Praplan A, Rissanen MP, Ruuskanen T, Santos FD, Schallhart S, Schnitzhofer R, Simon M, Smith JN, Tröstl J, Tsagkogeorgas G, Tomé A, Vaattovaara P, Vehkamäki H, Vrtala AE, Wagner PE, Williamson C, Wimmer D, Winkler PM, Virtanen A, Donahue NM, Carslaw KS, Baltensperger U, Riipinen I, Curtius J, Worsnop DR, Kulmala M.

Nat Commun. 2016 May 20;7:11594. doi: 10.1038/ncomms11594.

14.

Highly functionalized organic nitrates in the southeast United States: Contribution to secondary organic aerosol and reactive nitrogen budgets.

Lee BH, Mohr C, Lopez-Hilfiker FD, Lutz A, Hallquist M, Lee L, Romer P, Cohen RC, Iyer S, Kurtén T, Hu W, Day DA, Campuzano-Jost P, Jimenez JL, Xu L, Ng NL, Guo H, Weber RJ, Wild RJ, Brown SS, Koss A, de Gouw J, Olson K, Goldstein AH, Seco R, Kim S, McAvey K, Shepson PB, Starn T, Baumann K, Edgerton ES, Liu J, Shilling JE, Miller DO, Brune W, Schobesberger S, D'Ambro EL, Thornton JA.

Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1516-21. doi: 10.1073/pnas.1508108113. Epub 2016 Jan 25.

15.

Nanoscale, Voltage-Driven Application of Bioactive Substances onto Cells with Organized Topography.

Schobesberger S, Jönsson P, Buzuk A, Korchev Y, Siggers J, Gorelik J.

Biophys J. 2016 Jan 5;110(1):141-6. doi: 10.1016/j.bpj.2015.11.017.

16.

Microtubule-Dependent Mitochondria Alignment Regulates Calcium Release in Response to Nanomechanical Stimulus in Heart Myocytes.

Miragoli M, Sanchez-Alonso JL, Bhargava A, Wright PT, Sikkel M, Schobesberger S, Diakonov I, Novak P, Castaldi A, Cattaneo P, Lyon AR, Lab MJ, Gorelik J.

Cell Rep. 2016 Jan 5;14(1):140-151. doi: 10.1016/j.celrep.2015.12.014. Epub 2015 Dec 24.

17.

Direct Evidence for Microdomain-Specific Localization and Remodeling of Functional L-Type Calcium Channels in Rat and Human Atrial Myocytes.

Glukhov AV, Balycheva M, Sanchez-Alonso JL, Ilkan Z, Alvarez-Laviada A, Bhogal N, Diakonov I, Schobesberger S, Sikkel MB, Bhargava A, Faggian G, Punjabi PP, Houser SR, Gorelik J.

Circulation. 2015 Dec 22;132(25):2372-84. doi: 10.1161/CIRCULATIONAHA.115.018131. Epub 2015 Oct 8.

18.

Studying GPCR/cAMP pharmacology from the perspective of cellular structure.

Wright PT, Schobesberger S, Gorelik J.

Front Pharmacol. 2015 Jul 17;6:148. doi: 10.3389/fphar.2015.00148. eCollection 2015. Review.

19.

Insight into acid-base nucleation experiments by comparison of the chemical composition of positive, negative, and neutral clusters.

Bianchi F, Praplan AP, Sarnela N, Dommen J, Kürten A, Ortega IK, Schobesberger S, Junninen H, Simon M, Tröstl J, Jokinen T, Sipilä M, Adamov A, Amorim A, Almeida J, Breitenlechner M, Duplissy J, Ehrhart S, Flagan RC, Franchin A, Hakala J, Hansel A, Heinritzi M, Kangasluoma J, Keskinen H, Kim J, Kirkby J, Laaksonen A, Lawler MJ, Lehtipalo K, Leiminger M, Makhmutov V, Mathot S, Onnela A, Petäjä T, Riccobono F, Rissanen MP, Rondo L, Tomé A, Virtanen A, Viisanen Y, Williamson C, Wimmer D, Winkler PM, Ye P, Curtius J, Kulmala M, Worsnop DR, Donahue NM, Baltensperger U.

Environ Sci Technol. 2014 Dec 2;48(23):13675-84. doi: 10.1021/es502380b. Epub 2014 Nov 18.

PMID:
25406110
20.

Neutral molecular cluster formation of sulfuric acid-dimethylamine observed in real time under atmospheric conditions.

Kürten A, Jokinen T, Simon M, Sipilä M, Sarnela N, Junninen H, Adamov A, Almeida J, Amorim A, Bianchi F, Breitenlechner M, Dommen J, Donahue NM, Duplissy J, Ehrhart S, Flagan RC, Franchin A, Hakala J, Hansel A, Heinritzi M, Hutterli M, Kangasluoma J, Kirkby J, Laaksonen A, Lehtipalo K, Leiminger M, Makhmutov V, Mathot S, Onnela A, Petäjä T, Praplan AP, Riccobono F, Rissanen MP, Rondo L, Schobesberger S, Seinfeld JH, Steiner G, Tomé A, Tröstl J, Winkler PM, Williamson C, Wimmer D, Ye P, Baltensperger U, Carslaw KS, Kulmala M, Worsnop DR, Curtius J.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):15019-24. doi: 10.1073/pnas.1404853111. Epub 2014 Oct 6.

21.

Oxidation products of biogenic emissions contribute to nucleation of atmospheric particles.

Riccobono F, Schobesberger S, Scott CE, Dommen J, Ortega IK, Rondo L, Almeida J, Amorim A, Bianchi F, Breitenlechner M, David A, Downard A, Dunne EM, Duplissy J, Ehrhart S, Flagan RC, Franchin A, Hansel A, Junninen H, Kajos M, Keskinen H, Kupc A, Kürten A, Kvashin AN, Laaksonen A, Lehtipalo K, Makhmutov V, Mathot S, Nieminen T, Onnela A, Petäjä T, Praplan AP, Santos FD, Schallhart S, Seinfeld JH, Sipilä M, Spracklen DV, Stozhkov Y, Stratmann F, Tomé A, Tsagkogeorgas G, Vaattovaara P, Viisanen Y, Vrtala A, Wagner PE, Weingartner E, Wex H, Wimmer D, Carslaw KS, Curtius J, Donahue NM, Kirkby J, Kulmala M, Worsnop DR, Baltensperger U.

Science. 2014 May 16;344(6185):717-21. doi: 10.1126/science.1243527.

22.

A large source of low-volatility secondary organic aerosol.

Ehn M, Thornton JA, Kleist E, Sipilä M, Junninen H, Pullinen I, Springer M, Rubach F, Tillmann R, Lee B, Lopez-Hilfiker F, Andres S, Acir IH, Rissanen M, Jokinen T, Schobesberger S, Kangasluoma J, Kontkanen J, Nieminen T, Kurtén T, Nielsen LB, Jørgensen S, Kjaergaard HG, Canagaratna M, Maso MD, Berndt T, Petäjä T, Wahner A, Kerminen VM, Kulmala M, Worsnop DR, Wildt J, Mentel TF.

Nature. 2014 Feb 27;506(7489):476-9. doi: 10.1038/nature13032.

PMID:
24572423
23.

Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling.

Wright PT, Nikolaev VO, O'Hara T, Diakonov I, Bhargava A, Tokar S, Schobesberger S, Shevchuk AI, Sikkel MB, Wilkinson R, Trayanova NA, Lyon AR, Harding SE, Gorelik J.

J Mol Cell Cardiol. 2014 Feb;67:38-48. doi: 10.1016/j.yjmcc.2013.12.003. Epub 2013 Dec 15.

24.

Molecular understanding of atmospheric particle formation from sulfuric acid and large oxidized organic molecules.

Schobesberger S, Junninen H, Bianchi F, Lönn G, Ehn M, Lehtipalo K, Dommen J, Ehrhart S, Ortega IK, Franchin A, Nieminen T, Riccobono F, Hutterli M, Duplissy J, Almeida J, Amorim A, Breitenlechner M, Downard AJ, Dunne EM, Flagan RC, Kajos M, Keskinen H, Kirkby J, Kupc A, Kürten A, Kurtén T, Laaksonen A, Mathot S, Onnela A, Praplan AP, Rondo L, Santos FD, Schallhart S, Schnitzhofer R, Sipilä M, Tomé A, Tsagkogeorgas G, Vehkamäki H, Wimmer D, Baltensperger U, Carslaw KS, Curtius J, Hansel A, Petäjä T, Kulmala M, Donahue NM, Worsnop DR.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17223-8. doi: 10.1073/pnas.1306973110. Epub 2013 Oct 7.

25.

Molecular understanding of sulphuric acid-amine particle nucleation in the atmosphere.

Almeida J, Schobesberger S, Kürten A, Ortega IK, Kupiainen-Määttä O, Praplan AP, Adamov A, Amorim A, Bianchi F, Breitenlechner M, David A, Dommen J, Donahue NM, Downard A, Dunne E, Duplissy J, Ehrhart S, Flagan RC, Franchin A, Guida R, Hakala J, Hansel A, Heinritzi M, Henschel H, Jokinen T, Junninen H, Kajos M, Kangasluoma J, Keskinen H, Kupc A, Kurtén T, Kvashin AN, Laaksonen A, Lehtipalo K, Leiminger M, Leppä J, Loukonen V, Makhmutov V, Mathot S, McGrath MJ, Nieminen T, Olenius T, Onnela A, Petäjä T, Riccobono F, Riipinen I, Rissanen M, Rondo L, Ruuskanen T, Santos FD, Sarnela N, Schallhart S, Schnitzhofer R, Seinfeld JH, Simon M, Sipilä M, Stozhkov Y, Stratmann F, Tomé A, Tröstl J, Tsagkogeorgas G, Vaattovaara P, Viisanen Y, Virtanen A, Vrtala A, Wagner PE, Weingartner E, Wex H, Williamson C, Wimmer D, Ye P, Yli-Juuti T, Carslaw KS, Kulmala M, Curtius J, Baltensperger U, Worsnop DR, Vehkamäki H, Kirkby J.

Nature. 2013 Oct 17;502(7471):359-63. doi: 10.1038/nature12663. Epub 2013 Oct 6.

PMID:
24097350
26.

Direct observations of atmospheric aerosol nucleation.

Kulmala M, Kontkanen J, Junninen H, Lehtipalo K, Manninen HE, Nieminen T, Petäjä T, Sipilä M, Schobesberger S, Rantala P, Franchin A, Jokinen T, Järvinen E, Äijälä M, Kangasluoma J, Hakala J, Aalto PP, Paasonen P, Mikkilä J, Vanhanen J, Aalto J, Hakola H, Makkonen U, Ruuskanen T, Mauldin RL 3rd, Duplissy J, Vehkamäki H, Bäck J, Kortelainen A, Riipinen I, Kurtén T, Johnston MV, Smith JN, Ehn M, Mentel TF, Lehtinen KE, Laaksonen A, Kerminen VM, Worsnop DR.

Science. 2013 Feb 22;339(6122):943-6. doi: 10.1126/science.1227385.

27.

How do organic vapors contribute to new-particle formation?

Donahue NM, Ortega IK, Chuang W, Riipinen I, Riccobono F, Schobesberger S, Dommen J, Baltensperger U, Kulmala M, Worsnop DR, Vehkamaki H.

Faraday Discuss. 2013;165:91-104.

PMID:
24600998
28.

Comparing simulated and experimental molecular cluster distributions.

Olenius T, Schobesberger S, Kupiainen-Määttä O, Franchin A, Junninen H, Ortega IK, Kurtén T, Loukonen V, Worsnop DR, Kulmala M, Vehkamäki H.

Faraday Discuss. 2013;165:75-89.

PMID:
24600997
29.

Shape and compliance of endothelial cells after shear stress in vitro or from different aortic regions: scanning ion conductance microscopy study.

Potter CM, Schobesberger S, Lundberg MH, Weinberg PD, Mitchell JA, Gorelik J.

PLoS One. 2012;7(2):e31228. doi: 10.1371/journal.pone.0031228. Epub 2012 Feb 16.

30.

Role of sulphuric acid, ammonia and galactic cosmic rays in atmospheric aerosol nucleation.

Kirkby J, Curtius J, Almeida J, Dunne E, Duplissy J, Ehrhart S, Franchin A, Gagné S, Ickes L, Kürten A, Kupc A, Metzger A, Riccobono F, Rondo L, Schobesberger S, Tsagkogeorgas G, Wimmer D, Amorim A, Bianchi F, Breitenlechner M, David A, Dommen J, Downard A, Ehn M, Flagan RC, Haider S, Hansel A, Hauser D, Jud W, Junninen H, Kreissl F, Kvashin A, Laaksonen A, Lehtipalo K, Lima J, Lovejoy ER, Makhmutov V, Mathot S, Mikkilä J, Minginette P, Mogo S, Nieminen T, Onnela A, Pereira P, Petäjä T, Schnitzhofer R, Seinfeld JH, Sipilä M, Stozhkov Y, Stratmann F, Tomé A, Vanhanen J, Viisanen Y, Vrtala A, Wagner PE, Walther H, Weingartner E, Wex H, Winkler PM, Carslaw KS, Worsnop DR, Baltensperger U, Kulmala M.

Nature. 2011 Aug 24;476(7361):429-33. doi: 10.1038/nature10343.

PMID:
21866156
31.

Experiments on the temperature dependence of heterogeneous nucleation on nanometer-sized NaCl and Ag particles.

Schobesberger S, Winkler PM, Pinterich T, Vrtala A, Kulmala M, Wagner PE.

Chemphyschem. 2010 Dec 17;11(18):3874-82. doi: 10.1002/cphc.201000417.

PMID:
21038338

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