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Items: 1 to 50 of 109

1.

Interoperable and scalable data analysis with microservices: Applications in Metabolomics.

Emami Khoonsari P, Moreno P, Bergmann S, Burman J, Capuccini M, Carone M, Cascante M, de Atauri P, Foguet C, Gonzalez-Beltran A, Hankemeier T, Haug K, He S, Herman S, Johnson D, Kale N, Larsson A, Neumann S, Peters K, Pireddu L, Rocca-Serra P, Roger P, Rueedi R, Ruttkies C, Sadawi N, Salek RM, Sansone SA, Schober D, Selivanov V, Thévenot EA, van Vliet M, Zanetti G, Steinbeck C, Kultima K, Spjuth O.

Bioinformatics. 2019 Mar 9. pii: btz160. doi: 10.1093/bioinformatics/btz160. [Epub ahead of print]

PMID:
30851093
2.

PhenoMeNal: processing and analysis of metabolomics data in the cloud.

Peters K, Bradbury J, Bergmann S, Capuccini M, Cascante M, de Atauri P, Ebbels TMD, Foguet C, Glen R, Gonzalez-Beltran A, Günther UL, Handakas E, Hankemeier T, Haug K, Herman S, Holub P, Izzo M, Jacob D, Johnson D, Jourdan F, Kale N, Karaman I, Khalili B, Emami Khonsari P, Kultima K, Lampa S, Larsson A, Ludwig C, Moreno P, Neumann S, Novella JA, O'Donovan C, Pearce JTM, Peluso A, Piras ME, Pireddu L, Reed MAC, Rocca-Serra P, Roger P, Rosato A, Rueedi R, Ruttkies C, Sadawi N, Salek RM, Sansone SA, Selivanov V, Spjuth O, Schober D, Thévenot EA, Tomasoni M, van Rijswijk M, van Vliet M, Viant MR, Weber RJM, Zanetti G, Steinbeck C.

Gigascience. 2019 Feb 1;8(2). pii: giy149. doi: 10.1093/gigascience/giy149.

3.

In Vitro and In Vivo Correlation of Hepatic Fraction of Metabolism by P450 in Dogs.

Zhou X, Hui YH, Hudson L, Katyayan KK, Mohutsky MA, Hao J, Schober DA, Hembre EJ.

J Pharm Sci. 2019 Feb;108(2):1017-1026. doi: 10.1016/j.xphs.2018.09.012. Epub 2018 Sep 19.

PMID:
30244007
4.

Adapting an Evidence-based Cardiovascular Disease Risk Reduction Intervention to Rural Communities.

Johansson P, Schober D, Tutsch SF, Brueggeman G, Leon M, Lyden E, Schulz PS, Estabrooks P, Zimmerman L.

J Rural Health. 2019 Jan;35(1):87-96. doi: 10.1111/jrh.12306. Epub 2018 Jun 10.

PMID:
29888458
5.

In Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission Tomography.

Mogg AJ, Eessalu T, Johnson M, Wright R, Sanger HE, Xiao H, Crabtree MG, Smith A, Colvin EM, Schober D, Gehlert D, Jesudason C, Goldsmith PJ, Johnson MP, Felder CC, Barth VN, Broad LM.

J Pharmacol Exp Ther. 2018 Jun;365(3):602-613. doi: 10.1124/jpet.117.246454. Epub 2018 Apr 11.

PMID:
29643252
6.

Identification, expression and functional characterization of M4L, a muscarinic acetylcholine M4 receptor splice variant.

Schober DA, Croy CH, Ruble CL, Tao R, Felder CC.

PLoS One. 2017 Dec 6;12(12):e0188330. doi: 10.1371/journal.pone.0188330. eCollection 2017.

7.

The future of metabolomics in ELIXIR.

van Rijswijk M, Beirnaert C, Caron C, Cascante M, Dominguez V, Dunn WB, Ebbels TMD, Giacomoni F, Gonzalez-Beltran A, Hankemeier T, Haug K, Izquierdo-Garcia JL, Jimenez RC, Jourdan F, Kale N, Klapa MI, Kohlbacher O, Koort K, Kultima K, Le Corguillé G, Moreno P, Moschonas NK, Neumann S, O'Donovan C, Reczko M, Rocca-Serra P, Rosato A, Salek RM, Sansone SA, Satagopam V, Schober D, Shimmo R, Spicer RA, Spjuth O, Thévenot EA, Viant MR, Weber RJM, Willighagen EL, Zanetti G, Steinbeck C.

Version 2. F1000Res. 2017 Sep 6 [revised 2017 Jan 1];6. pii: ELIXIR-1649. doi: 10.12688/f1000research.12342.2. eCollection 2017.

8.

Targeted Blockade of TARP-γ8-Associated AMPA Receptors: Anticonvulsant Activity with the Selective Antagonist LY3130481 (CERC-611).

Witkin JM, Schober DA, Gleason SD, Catlow JT, Porter WJ, Reel J, Jin X, Hobbs J, Gehlert D, Gernert DL, Gardinier KM, Kato AS, Ping X, Smith JL.

CNS Neurol Disord Drug Targets. 2017;16(10):1099-1110. doi: 10.2174/1871527316666171101132047.

PMID:
29090671
9.

nmrML: A Community Supported Open Data Standard for the Description, Storage, and Exchange of NMR Data.

Schober D, Jacob D, Wilson M, Cruz JA, Marcu A, Grant JR, Moing A, Deborde C, de Figueiredo LF, Haug K, Rocca-Serra P, Easton J, Ebbels TMD, Hao J, Ludwig C, Günther UL, Rosato A, Klein MS, Lewis IA, Luchinat C, Jones AR, Grauslys A, Larralde M, Yokochi M, Kobayashi N, Porzel A, Griffin JL, Viant MR, Wishart DS, Steinbeck C, Salek RM, Neumann S.

Anal Chem. 2018 Jan 2;90(1):649-656. doi: 10.1021/acs.analchem.7b02795. Epub 2017 Dec 14.

10.

Implementing the Academy of Nutrition and Dietetics Benchmarks for Nutrition Education for Children: Child-Care Providers' Perspectives.

Dev DA, Carraway-Stage V, Schober DJ, McBride BA, Kok CM, Ramsay S.

J Acad Nutr Diet. 2017 Dec;117(12):1963-1971.e2. doi: 10.1016/j.jand.2017.07.001. Epub 2017 Aug 24.

PMID:
28844891
11.

Structural Determinants of the γ-8 TARP Dependent AMPA Receptor Antagonist.

Lee MR, Gardinier KM, Gernert DL, Schober DA, Wright RA, Wang H, Qian Y, Witkin JM, Nisenbaum ES, Kato AS.

ACS Chem Neurosci. 2017 Dec 20;8(12):2631-2647. doi: 10.1021/acschemneuro.7b00186. Epub 2017 Sep 5.

PMID:
28825787
12.

Psychiatric Comorbidities and BMI: An Exploratory Analysis.

Guenzel N, Schober DJ.

Issues Ment Health Nurs. 2017 Sep;38(9):698-704. doi: 10.1080/01612840.2017.1341588. Epub 2017 Jul 26.

PMID:
28745915
13.

Promoting colorectal cancer screening through a new model of delivering rural primary care in the USA: a qualitative study.

Kim J, Young L, Bekmuratova S, Schober DJ, Wang H, Roy S, Bhuyan SS, Schumaker A, Chen LW.

Rural Remote Health. 2017 Jan-Mar;17(1):4187. Epub 2017 Mar 29.

14.

Further Evaluation of Mechanisms Associated with the Antidepressantlike Signature of Scopolamine in Mice.

Martin AE, Schober DA, Nikolayev A, Tolstikov VV, Anderson WH, Higgs RE, Kuo MS, Laksmanan A, Catlow JT, Li X, Felder CC, Witkin JM.

CNS Neurol Disord Drug Targets. 2017;16(4):492-500. doi: 10.2174/1871527316666170309142646.

PMID:
28294051
15.

Translational Pharmacology of the Metabotropic Glutamate 2 Receptor-Preferring Agonist LY2812223 in the Animal and Human Brain.

Felder CC, Schober DA, Tu Y, Quets A, Xiao H, Watt M, Siuda E, Nisenbaum E, Xiang C, Heinz B, Prieto L, McKinzie DL, Monn JA.

J Pharmacol Exp Ther. 2017 Apr;361(1):190-197. doi: 10.1124/jpet.116.237859. Epub 2017 Jan 30.

PMID:
28138041
16.

Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism.

Kato AS, Burris KD, Gardinier KM, Gernert DL, Porter WJ, Reel J, Ding C, Tu Y, Schober DA, Lee MR, Heinz BA, Fitch TE, Gleason SD, Catlow JT, Yu H, Fitzjohn SM, Pasqui F, Wang H, Qian Y, Sher E, Zwart R, Wafford KA, Rasmussen K, Ornstein PL, Isaac JT, Nisenbaum ES, Bredt DS, Witkin JM.

Nat Med. 2016 Dec;22(12):1496-1501. doi: 10.1038/nm.4221. Epub 2016 Nov 7.

PMID:
27820603
17.

Post-mortem CT: Hounsfield unit profiles obtained in the lungs with respect to the cause of death assessment.

Schober D, Schwendener N, Zech WD, Jackowski C.

Int J Legal Med. 2017 Jan;131(1):199-210. doi: 10.1007/s00414-016-1454-9. Epub 2016 Oct 20.

PMID:
27766411
18.

Creating Supportive Breastfeeding Policies in Early Childhood Education Programs: A Qualitative Study from a Multi-Site Intervention.

Calloway EE, Stern KL, Schober DJ, Yaroch AL.

Matern Child Health J. 2017 Apr;21(4):809-817. doi: 10.1007/s10995-016-2174-y.

PMID:
27520557
19.

The relationship between physical activity and diet and young children's cognitive development: A systematic review.

Tandon PS, Tovar A, Jayasuriya AT, Welker E, Schober DJ, Copeland K, Dev DA, Murriel AL, Amso D, Ward DS.

Prev Med Rep. 2016 Apr 22;3:379-90. doi: 10.1016/j.pmedr.2016.04.003. eCollection 2016 Jun. Review.

20.

Evaluation of the LiveWell@School Food Initiative Shows Increases in Scratch Cooking and Improvement in Nutritional Content.

Schober DJ, Carpenter L, Currie V, Yaroch AL.

J Sch Health. 2016 Aug;86(8):604-11. doi: 10.1111/josh.12413.

PMID:
27374350
21.

The Ontology for Biomedical Investigations.

Bandrowski A, Brinkman R, Brochhausen M, Brush MH, Bug B, Chibucos MC, Clancy K, Courtot M, Derom D, Dumontier M, Fan L, Fostel J, Fragoso G, Gibson F, Gonzalez-Beltran A, Haendel MA, He Y, Heiskanen M, Hernandez-Boussard T, Jensen M, Lin Y, Lister AL, Lord P, Malone J, Manduchi E, McGee M, Morrison N, Overton JA, Parkinson H, Peters B, Rocca-Serra P, Ruttenberg A, Sansone SA, Scheuermann RH, Schober D, Smith B, Soldatova LN, Stoeckert CJ Jr, Taylor CF, Torniai C, Turner JA, Vita R, Whetzel PL, Zheng J.

PLoS One. 2016 Apr 29;11(4):e0154556. doi: 10.1371/journal.pone.0154556. eCollection 2016.

22.

Data standards can boost metabolomics research, and if there is a will, there is a way.

Rocca-Serra P, Salek RM, Arita M, Correa E, Dayalan S, Gonzalez-Beltran A, Ebbels T, Goodacre R, Hastings J, Haug K, Koulman A, Nikolski M, Oresic M, Sansone SA, Schober D, Smith J, Steinbeck C, Viant MR, Neumann S.

Metabolomics. 2016;12:14. doi: 10.1007/s11306-015-0879-3. Epub 2015 Nov 17. Review.

23.

Developing an Academic-Community Partnership to Promote Soccer-Based Physical Activity Among Latino Youth.

Schober DJ, Zarate J, Fawcett SB.

Prog Community Health Partnersh. 2015 Autumn;9(3):397-404. doi: 10.1353/cpr.2015.0052.

PMID:
26548791
24.

COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access.

Salek RM, Neumann S, Schober D, Hummel J, Billiau K, Kopka J, Correa E, Reijmers T, Rosato A, Tenori L, Turano P, Marin S, Deborde C, Jacob D, Rolin D, Dartigues B, Conesa P, Haug K, Rocca-Serra P, O'Hagan S, Hao J, van Vliet M, Sysi-Aho M, Ludwig C, Bouwman J, Cascante M, Ebbels T, Griffin JL, Moing A, Nikolski M, Oresic M, Sansone SA, Viant MR, Goodacre R, Günther UL, Hankemeier T, Luchinat C, Walther D, Steinbeck C.

Metabolomics. 2015;11(6):1587-1597. Epub 2015 May 26.

25.

Using Action Planning to Build Organizational Capacity for the Prevention of Intimate Partner Violence.

Schober DJ, Fawcett SB.

Health Educ Behav. 2015 Aug;42(4):449-57. doi: 10.1177/1090198114564501.

PMID:
26245933
26.

A workplace farmstand pilot programme in Omaha, Nebraska, USA.

Bertmann FM, Fricke HE, Carpenter LR, Schober DJ, Smith TM, Pinard CA, Yaroch AL.

Public Health Nutr. 2015 Sep;18(13):2402-6. doi: 10.1017/S1368980015001706. Epub 2015 May 28. Review.

PMID:
26016406
27.

A Qualitative Exploration of Community-Based Organization Programs, Resources, and Training to Promote Adolescent Sexual Health.

McCarthy M, Fisher CM, Zhou J, Kneip Pelster AD, Schober D, Baldwin K, Fortenberry J, Goldsworthy R.

Am J Sex Educ. 2015;10(4):316-332. Epub 2015 Dec 11.

28.

Discovering Sexual Health Conversations between Adolescents and Youth Development Professionals.

Gupta N, Chandak A, Gilson G, Pelster AK, Schober DJ, Goldsworthy R, Baldwin K, Fortenberry JD, Fisher C.

Am J Sex Educ. 2015 Jan 1;10(1):21-39. Epub 2015 Mar 20.

29.

A conceptual framework for organizational readiness to implement nutrition and physical activity programs in early childhood education settings.

Sharma SV, Upadhyaya M, Schober DJ, Byrd-Williams C.

Prev Chronic Dis. 2014 Oct 30;11:E190. doi: 10.5888/pcd11.140166.

30.

M1 and m2 muscarinic receptor subtypes regulate antidepressant-like effects of the rapidly acting antidepressant scopolamine.

Witkin JM, Overshiner C, Li X, Catlow JT, Wishart GN, Schober DA, Heinz BA, Nikolayev A, Tolstikov VV, Anderson WH, Higgs RE, Kuo MS, Felder CC.

J Pharmacol Exp Ther. 2014 Nov;351(2):448-56. doi: 10.1124/jpet.114.216804. Epub 2014 Sep 3.

PMID:
25187432
31.

Development of a radioligand, [(3)H]LY2119620, to probe the human M(2) and M(4) muscarinic receptor allosteric binding sites.

Schober DA, Croy CH, Xiao H, Christopoulos A, Felder CC.

Mol Pharmacol. 2014 Jul;86(1):116-23. doi: 10.1124/mol.114.091785. Epub 2014 May 7.

PMID:
24807966
32.

Characterization of the novel positive allosteric modulator, LY2119620, at the muscarinic M(2) and M(4) receptors.

Croy CH, Schober DA, Xiao H, Quets A, Christopoulos A, Felder CC.

Mol Pharmacol. 2014 Jul;86(1):106-15. doi: 10.1124/mol.114.091751. Epub 2014 May 7.

PMID:
24807965
33.

An empirical case study of the effects of training and technical assistance on community coalition functioning and sustainability.

Keene Woods N, Watson-Thompson J, Schober DJ, Markt B, Fawcett S.

Health Promot Pract. 2014 Sep;15(5):739-49. doi: 10.1177/1524839914525174. Epub 2014 Mar 24.

PMID:
24662898
34.

LSN2424100: a novel, potent orexin-2 receptor antagonist with selectivity over orexin-1 receptors and activity in an animal model predictive of antidepressant-like efficacy.

Fitch TE, Benvenga MJ, Jesudason CD, Zink C, Vandergriff AB, Menezes MM, Schober DA, Rorick-Kehn LM.

Front Neurosci. 2014 Jan 28;8:5. doi: 10.3389/fnins.2014.00005. eCollection 2014.

35.

Enhancing the capacity of substance abuse prevention coalitions through training and technical assistance.

Watson-Thompson J, Woods NK, Schober DJ, Schultz JA.

J Prev Interv Community. 2013;41(3):176-87. doi: 10.1080/10852352.2013.788345.

PMID:
23751061
36.

Supporting a community-based participatory evaluation approach to violence prevention in Kansas City.

Watson-Thompson J, Jones MD, Colvin JD, McClendon-Cole T, Schober DJ, Johnson AM.

J Prev Interv Community. 2013;41(3):155-66. doi: 10.1080/10852352.2013.788342.

PMID:
23751059
37.

Effects of guideline-based training on the quality of formal ontologies: a randomized controlled trial.

Boeker M, Jansen L, Grewe N, Röhl J, Schober D, Seddig-Raufie D, Schulz S.

PLoS One. 2013 May 7;8(5):e61425. doi: 10.1371/journal.pone.0061425. Print 2013.

38.

Towards an ontological representation of morbidity and mortality in Description Logics.

Santana F, Freitas F, Fernandes R, Medeiros Z, Schober D.

J Biomed Semantics. 2012 Sep 21;3 Suppl 2:S7. doi: 10.1186/2041-1480-3-S2-S7. Epub 2012 Sep 21.

39.

OntoCheck: verifying ontology naming conventions and metadata completeness in Protégé 4.

Schober D, Tudose I, Svatek V, Boeker M.

J Biomed Semantics. 2012 Sep 21;3 Suppl 2:S4. doi: 10.1186/2041-1480-3-S2-S4. Epub 2012 Sep 21.

40.

Proposed actions are no actions: re-modeling an ontology design pattern with a realist top-level ontology.

Seddig-Raufie D, Jansen L, Schober D, Boeker M, Grewe N, Schulz S.

J Biomed Semantics. 2012 Sep 21;3 Suppl 2:S2. doi: 10.1186/2041-1480-3-S2-S2. Epub 2012 Sep 21.

41.

The Enough Abuse Campaign: building the movement to prevent child sexual abuse in Massachusetts.

Schober DJ, Fawcett SB, Bernier J.

J Child Sex Abus. 2012;21(4):456-69. doi: 10.1080/10538712.2012.675423.

PMID:
22809049
42.

Preserved morphology and physiology of excitatory synapses in profilin1-deficient mice.

Görlich A, Zimmermann AM, Schober D, Böttcher RT, Sassoè-Pognetto M, Friauf E, Witke W, Rust MB.

PLoS One. 2012;7(1):e30068. doi: 10.1371/journal.pone.0030068. Epub 2012 Jan 11.

43.

Unintended consequences of existential quantifications in biomedical ontologies.

Boeker M, Tudose I, Hastings J, Schober D, Schulz S.

BMC Bioinformatics. 2011 Nov 24;12:456. doi: 10.1186/1471-2105-12-456.

44.

Interoperability driven integration of biomedical data sources.

Teodoro D, Choquet R, Schober D, Mels G, Pasche E, Ruch P, Lovis C.

Stud Health Technol Inform. 2011;169:185-9.

PMID:
21893739
45.

Ontology patterns for tabular representations of biomedical knowledge on neglected tropical diseases.

Santana F, Schober D, Medeiros Z, Freitas F, Schulz S.

Bioinformatics. 2011 Jul 1;27(13):i349-56. doi: 10.1093/bioinformatics/btr226.

46.

Pharmacological characterization of LY593093, an M1 muscarinic acetylcholine receptor-selective partial orthosteric agonist.

Watt ML, Schober DA, Hitchcock S, Liu B, Chesterfield AK, McKinzie D, Felder CC.

J Pharmacol Exp Ther. 2011 Aug;338(2):622-32. doi: 10.1124/jpet.111.182063. Epub 2011 May 10.

PMID:
21558436
47.

The Pitfalls of Thesaurus Ontologization - the Case of the NCI Thesaurus.

Schulz S, Schober D, Tudose I, Stenzhorn H.

AMIA Annu Symp Proc. 2010 Nov 13;2010:727-31.

48.

Transmembrane AMPA receptor regulatory proteins and cornichon-2 allosterically regulate AMPA receptor antagonists and potentiators.

Schober DA, Gill MB, Yu H, Gernert DL, Jeffries MW, Ornstein PL, Kato AS, Felder CC, Bredt DS.

J Biol Chem. 2011 Apr 15;286(15):13134-42. doi: 10.1074/jbc.M110.212522. Epub 2011 Feb 22.

49.

Improving collaboration for effective violence surveillance and health promotion.

Schober DJ, Ramaswamy M, Choi WS, Fawcett SB, Hindman J, Martinez JM.

J Public Health Manag Pract. 2011 Mar-Apr;17(2):174-6. doi: 10.1097/PHH.0b013e3181f5424a. No abstract available.

PMID:
21297414
50.

The DebugIT core ontology: semantic integration of antibiotics resistance patterns.

Schober D, Boeker M, Bullenkamp J, Huszka C, Depraetere K, Teodoro D, Nadah N, Choquet R, Daniel C, Schulz S.

Stud Health Technol Inform. 2010;160(Pt 2):1060-4.

PMID:
20841846

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