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Items: 7


LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells.

Trepte P, Kruse S, Kostova S, Hoffmann S, Buntru A, Tempelmeier A, Secker C, Diez L, Schulz A, Klockmeier K, Zenkner M, Golusik S, Rau K, Schnoegl S, Garner CC, Wanker EE.

Mol Syst Biol. 2018 Jul 11;14(7):e8071. doi: 10.15252/msb.20178071.


A Filter Retardation Assay Facilitates the Detection and Quantification of Heat-Stable, Amyloidogenic Mutant Huntingtin Aggregates in Complex Biosamples.

Ast A, Schindler F, Buntru A, Schnoegl S, Wanker EE.

Methods Mol Biol. 2018;1780:31-40. doi: 10.1007/978-1-4939-7825-0_3.


Current Approaches Toward Quantitative Mapping of the Interactome.

Buntru A, Trepte P, Klockmeier K, Schnoegl S, Wanker EE.

Front Genet. 2016 May 4;7:74. doi: 10.3389/fgene.2016.00074. eCollection 2016.


Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity.

Stroedicke M, Bounab Y, Strempel N, Klockmeier K, Yigit S, Friedrich RP, Chaurasia G, Li S, Hesse F, Riechers SP, Russ J, Nicoletti C, Boeddrich A, Wiglenda T, Haenig C, Schnoegl S, Fournier D, Graham RK, Hayden MR, Sigrist S, Bates GP, Priller J, Andrade-Navarro MA, Futschik ME, Wanker EE.

Genome Res. 2015 May;25(5):701-13. doi: 10.1101/gr.182444.114.


Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils.

Bieschke J, Herbst M, Wiglenda T, Friedrich RP, Boeddrich A, Schiele F, Kleckers D, Lopez del Amo JM, Grüning BA, Wang Q, Schmidt MR, Lurz R, Anwyl R, Schnoegl S, Fändrich M, Frank RF, Reif B, Günther S, Walsh DM, Wanker EE.

Nat Chem Biol. 2011 Nov 20;8(1):93-101. doi: 10.1038/nchembio.719.


Pathogenic polyglutamine tracts are potent inducers of spontaneous Sup35 and Rnq1 amyloidogenesis.

Goehler H, Dröge A, Lurz R, Schnoegl S, Chernoff YO, Wanker EE.

PLoS One. 2010 Mar 10;5(3):e9642. doi: 10.1371/journal.pone.0009642.


UniHI 4: new tools for query, analysis and visualization of the human protein-protein interactome.

Chaurasia G, Malhotra S, Russ J, Schnoegl S, Hänig C, Wanker EE, Futschik ME.

Nucleic Acids Res. 2009 Jan;37(Database issue):D657-60. doi: 10.1093/nar/gkn841. Epub 2008 Nov 4.

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