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Items: 23

1.

LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice.

Herzig MC, Kolly C, Persohn E, Theil D, Schweizer T, Hafner T, Stemmelen C, Troxler TJ, Schmid P, Danner S, Schnell CR, Mueller M, Kinzel B, Grevot A, Bolognani F, Stirn M, Kuhn RR, Kaupmann K, van der Putten PH, Rovelli G, Shimshek DR.

Hum Mol Genet. 2011 Nov 1;20(21):4209-23. doi: 10.1093/hmg/ddr348. Epub 2011 Aug 9.

2.

mTOR inhibitor RAD001 (everolimus) has antiangiogenic/vascular properties distinct from a VEGFR tyrosine kinase inhibitor.

Lane HA, Wood JM, McSheehy PM, Allegrini PR, Boulay A, Brueggen J, Littlewood-Evans A, Maira SM, Martiny-Baron G, Schnell CR, Sini P, O'Reilly T.

Clin Cancer Res. 2009 Mar 1;15(5):1612-22. doi: 10.1158/1078-0432.CCR-08-2057. Epub 2009 Feb 17.

3.

Effects of the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 on the tumor vasculature: implications for clinical imaging.

Schnell CR, Stauffer F, Allegrini PR, O'Reilly T, McSheehy PM, Dartois C, Stumm M, Cozens R, Littlewood-Evans A, García-Echeverría C, Maira SM.

Cancer Res. 2008 Aug 15;68(16):6598-607. doi: 10.1158/0008-5472.CAN-08-1044.

4.

Structural modification of the P2' position of 2,7-dialkyl-substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamides: the discovery of aliskiren, a potent nonpeptide human renin inhibitor active after once daily dosing in marmosets.

Maibaum J, Stutz S, Göschke R, Rigollier P, Yamaguchi Y, Cumin F, Rahuel J, Baum HP, Cohen NC, Schnell CR, Fuhrer W, Gruetter MG, Schilling W, Wood JM.

J Med Chem. 2007 Oct 4;50(20):4832-44. Epub 2007 Sep 8.

PMID:
17824680
5.

Novel 2,7-dialkyl-substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamide transition state peptidomimetics are potent and orally active inhibitors of human renin.

Göschke R, Stutz S, Rasetti V, Cohen NC, Rahuel J, Rigollier P, Baum HP, Forgiarini P, Schnell CR, Wagner T, Gruetter MG, Fuhrer W, Schilling W, Cumin F, Wood JM, Maibaum J.

J Med Chem. 2007 Oct 4;50(20):4818-31. Epub 2007 Sep 8.

PMID:
17824679
6.

Behavioral and physiological effects of an infant-neglect manipulation in a bi-parental, twinning primate: impact is dependent on familial factors.

Dettling AC, Schnell CR, Maier C, Feldon J, Pryce CR.

Psychoneuroendocrinology. 2007 May;32(4):331-49. Epub 2007 Mar 23.

PMID:
17363175
7.

Autonomic arousal in an appetitive context in primates: a behavioural and neural analysis.

Braesicke K, Parkinson JA, Reekie Y, Man MS, Hopewell L, Pears A, Crofts H, Schnell CR, Roberts AC.

Eur J Neurosci. 2005 Mar;21(6):1733-40.

PMID:
15845101
8.

Aliskiren, a novel, orally effective renin inhibitor, lowers blood pressure in marmosets and spontaneously hypertensive rats.

Wood JM, Schnell CR, Cumin F, Menard J, Webb RL.

J Hypertens. 2005 Feb;23(2):417-26.

PMID:
15662231
9.

Deprivation of parenting disrupts development of homeostatic and reward systems in marmoset monkey offspring.

Pryce CR, Dettling AC, Spengler M, Schnell CR, Feldon J.

Biol Psychiatry. 2004 Jul 15;56(2):72-9.

PMID:
15231438
10.
11.

Structure-based design of aliskiren, a novel orally effective renin inhibitor.

Wood JM, Maibaum J, Rahuel J, Grütter MG, Cohen NC, Rasetti V, Rüger H, Göschke R, Stutz S, Fuhrer W, Schilling W, Rigollier P, Yamaguchi Y, Cumin F, Baum HP, Schnell CR, Herold P, Mah R, Jensen C, O'Brien E, Stanton A, Bedigian MP.

Biochem Biophys Res Commun. 2003 Sep 5;308(4):698-705.

PMID:
12927775
12.

Anthranilic acid amides: a novel class of antiangiogenic VEGF receptor kinase inhibitors.

Manley PW, Furet P, Bold G, Brüggen J, Mestan J, Meyer T, Schnell CR, Wood J, Haberey M, Huth A, Krüger M, Menrad A, Ottow E, Seidelmann D, Siemeister G, Thierauch KH.

J Med Chem. 2002 Dec 19;45(26):5687-93.

PMID:
12477352
13.
14.
15.
16.

Measurement of intraocular pressure by telemetry in conscious, unrestrained rabbits.

Schnell CR, Debon C, Percicot CL.

Invest Ophthalmol Vis Sci. 1996 May;37(6):958-65.

PMID:
8631639
17.
18.
19.

Measurement of blood pressure and heart rate by telemetry in conscious, unrestrained marmosets.

Schnell CR, Wood JM.

Am J Physiol. 1993 May;264(5 Pt 2):H1509-16.

PMID:
8498565
20.
21.

Granulopoiesis in bone marrow and spleen in chronic myeloid leukaemia.

Brandt L, Schnell CR.

Scand J Haematol. 1969;6(1):65-8. No abstract available.

PMID:
5257576
22.

[Fundus oculi hemorrhage in anemia].

Bengtsson C, Biörklund H, Schnell CR.

Nord Med. 1966 Feb 10;75(6):161-3. Swedish. No abstract available.

PMID:
5902341
23.

[A case of alkylphosphate poisoning].

SCHNELL CR.

Sven Lakartidn. 1963 Feb 14;60:472-6. Swedish. No abstract available.

PMID:
13992209

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