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Items: 1 to 50 of 151

1.

Glutaredoxin1 Diminishes Amyloid Beta-Mediated Oxidation of F-Actin and Reverses Cognitive Deficits in an Alzheimer's Disease Mouse Model.

Kommaddi RP, Tomar DS, Karunakaran S, Bapat D, Nanguneri S, Ray A, Schneider BL, Nair D, Ravindranath V.

Antioxid Redox Signal. 2019 Dec 20;31(18):1321-1338. doi: 10.1089/ars.2019.7754.

PMID:
31617375
2.

Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss.

György B, Nist-Lund C, Pan B, Asai Y, Karavitaki KD, Kleinstiver BP, Garcia SP, Zaborowski MP, Solanes P, Spataro S, Schneider BL, Joung JK, Géléoc GSG, Holt JR, Corey DP.

Nat Med. 2019 Jul;25(7):1123-1130. doi: 10.1038/s41591-019-0500-9. Epub 2019 Jul 3.

PMID:
31270503
3.

Altered interplay between endoplasmic reticulum and mitochondria in Charcot-Marie-Tooth type 2A neuropathy.

Bernard-Marissal N, van Hameren G, Juneja M, Pellegrino C, Louhivuori L, Bartesaghi L, Rochat C, El Mansour O, Médard JJ, Croisier M, Maclachlan C, Poirot O, Uhlén P, Timmerman V, Tricaud N, Schneider BL, Chrast R.

Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2328-2337. doi: 10.1073/pnas.1810932116. Epub 2019 Jan 18.

4.

The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging.

D'Amico D, Mottis A, Potenza F, Sorrentino V, Li H, Romani M, Lemos V, Schoonjans K, Zamboni N, Knott G, Schneider BL, Auwerx J.

Mol Cell. 2019 Feb 21;73(4):775-787.e10. doi: 10.1016/j.molcel.2018.11.034. Epub 2019 Jan 11.

PMID:
30642763
5.

Scalable Production of AAV Vectors in Orbitally Shaken HEK293 Cells.

Blessing D, Vachey G, Pythoud C, Rey M, Padrun V, Wurm FM, Schneider BL, Déglon N.

Mol Ther Methods Clin Dev. 2018 Nov 22;13:14-26. doi: 10.1016/j.omtm.2018.11.004. eCollection 2019 Jun 14.

6.

Scalable Production and Purification of Adeno-Associated Viral Vectors (AAV).

Blessing D, Déglon N, Schneider BL.

Methods Mol Biol. 2018;1850:259-274. doi: 10.1007/978-1-4939-8730-6_17.

PMID:
30242692
7.

Exogenous LRRK2G2019S induces parkinsonian-like pathology in a nonhuman primate.

Mestre-Francés N, Serratrice N, Gennetier A, Devau G, Cobo S, Trouche SG, Fontès P, Zussy C, De Deurwaerdere P, Salinas S, Mennechet FJ, Dusonchet J, Schneider BL, Saggio I, Kalatzis V, Luquin-Piudo MR, Verdier JM, Kremer EJ.

JCI Insight. 2018 Jul 26;3(14). pii: 98202. doi: 10.1172/jci.insight.98202. eCollection 2018 Jul 26.

8.

Yeast lifespan variation correlates with cell growth and SIR2 expression.

Smith JT, White JW, Dungrawala H, Hua H, Schneider BL.

PLoS One. 2018 Jul 6;13(7):e0200275. doi: 10.1371/journal.pone.0200275. eCollection 2018.

9.

Cortico-reticulo-spinal circuit reorganization enables functional recovery after severe spinal cord contusion.

Asboth L, Friedli L, Beauparlant J, Martinez-Gonzalez C, Anil S, Rey E, Baud L, Pidpruzhnykova G, Anderson MA, Shkorbatova P, Batti L, Pagès S, Kreider J, Schneider BL, Barraud Q, Courtine G.

Nat Neurosci. 2018 Apr;21(4):576-588. doi: 10.1038/s41593-018-0093-5. Epub 2018 Mar 19.

PMID:
29556028
10.

Endoplasmic reticulum and mitochondria in diseases of motor and sensory neurons: a broken relationship?

Bernard-Marissal N, Chrast R, Schneider BL.

Cell Death Dis. 2018 Feb 28;9(3):333. doi: 10.1038/s41419-017-0125-1. Review.

11.

PFN2 and GAMT as common molecular determinants of axonal Charcot-Marie-Tooth disease.

Juneja M, Azmi A, Baets J, Roos A, Jennings MJ, Saveri P, Pisciotta C, Bernard-Marissal N, Schneider BL, Verfaillie C, Chrast R, Seeman P, Hahn AF, de Jonghe P, Maudsley S, Horvath R, Pareyson D, Timmerman V.

J Neurol Neurosurg Psychiatry. 2018 Aug;89(8):870-878. doi: 10.1136/jnnp-2017-317562. Epub 2018 Feb 15.

PMID:
29449460
12.

Evolution of the neurochemical profiles in the G93A-SOD1 mouse model of amyotrophic lateral sclerosis.

Lei H, Dirren E, Poitry-Yamate C, Schneider BL, Gruetter R, Aebischer P.

J Cereb Blood Flow Metab. 2019 Jul;39(7):1283-1298. doi: 10.1177/0271678X18756499. Epub 2018 Feb 5.

PMID:
29400109
13.

Pathogenic commonalities between spinal muscular atrophy and amyotrophic lateral sclerosis: Converging roads to therapeutic development.

Bowerman M, Murray LM, Scamps F, Schneider BL, Kothary R, Raoul C.

Eur J Med Genet. 2018 Nov;61(11):685-698. doi: 10.1016/j.ejmg.2017.12.001. Epub 2017 Dec 5. Review.

PMID:
29313812
14.

Modulating the catalytic activity of AMPK has neuroprotective effects against α-synuclein toxicity.

Bobela W, Nazeeruddin S, Knott G, Aebischer P, Schneider BL.

Mol Neurodegener. 2017 Nov 3;12(1):80. doi: 10.1186/s13024-017-0220-x.

15.

In vivo neurochemical measurements in cerebral tissues using a droplet-based monitoring system.

Petit-Pierre G, Colin P, Laurer E, Déglon J, Bertsch A, Thomas A, Schneider BL, Renaud P.

Nat Commun. 2017 Nov 1;8(1):1239. doi: 10.1038/s41467-017-01419-1.

16.

G2019S LRRK2 enhances the neuronal transmission of tau in the mouse brain.

Nguyen APT, Daniel G, Valdés P, Islam MS, Schneider BL, Moore DJ.

Hum Mol Genet. 2018 Jan 1;27(1):120-134. doi: 10.1093/hmg/ddx389.

PMID:
29088368
17.

Motifs in the tau protein that control binding to microtubules and aggregation determine pathological effects.

Lathuilière A, Valdés P, Papin S, Cacquevel M, Maclachlan C, Knott GW, Muhs A, Paganetti P, Schneider BL.

Sci Rep. 2017 Oct 19;7(1):13556. doi: 10.1038/s41598-017-13786-2.

18.

Alpha-synuclein ferrireductase activity is detectible in vivo, is altered in Parkinson's disease and increases the neurotoxicity of DOPAL.

McDowall JS, Ntai I, Honeychurch KC, Hart JP, Colin P, Schneider BL, Brown DR.

Mol Cell Neurosci. 2017 Dec;85:1-11. doi: 10.1016/j.mcn.2017.08.001. Epub 2017 Aug 12.

PMID:
28811225
19.

α-Synuclein increases β-amyloid secretion by promoting β-/γ-secretase processing of APP.

Roberts HL, Schneider BL, Brown DR.

PLoS One. 2017 Feb 10;12(2):e0171925. doi: 10.1371/journal.pone.0171925. eCollection 2017.

20.

[A bioactive implantable device to prevent Alzheimer's disease].

Lathuilière A, Schneider BL.

Med Sci (Paris). 2017 Jan;33(1):81-84. doi: 10.1051/medsci/20173301013. Epub 2017 Jan 25. French. No abstract available.

21.

Gene Therapy: A Promising Approach for Neuroprotection in Parkinson's Disease?

Valdés P, Schneider BL.

Front Neuroanat. 2016 Dec 20;10:123. doi: 10.3389/fnana.2016.00123. eCollection 2016. Review.

22.

Parkin functionally interacts with PGC-1α to preserve mitochondria and protect dopaminergic neurons.

Zheng L, Bernard-Marissal N, Moullan N, D'Amico D, Auwerx J, Moore DJ, Knott G, Aebischer P, Schneider BL.

Hum Mol Genet. 2017 Feb 1;26(3):582-598. doi: 10.1093/hmg/ddw418.

PMID:
28053050
23.

Synchronization of Yeast.

Smith J, Manukyan A, Hua H, Dungrawala H, Schneider BL.

Methods Mol Biol. 2017;1524:215-242.

PMID:
27815906
24.

Lentiviral Vectors for the Engineering of Implantable Cells Secreting Recombinant Antibodies.

Lathuilière A, Schneider BL.

Methods Mol Biol. 2016;1448:139-55. doi: 10.1007/978-1-4939-3753-0_11.

PMID:
27317179
25.

Impaired Ethanol-Induced Sensitization and Decreased Cannabinoid Receptor-1 in a Model of Posttraumatic Stress Disorder.

Matchynski-Franks JJ, Susick LL, Schneider BL, Perrine SA, Conti AC.

PLoS One. 2016 May 17;11(5):e0155759. doi: 10.1371/journal.pone.0155759. eCollection 2016.

26.

A subcutaneous cellular implant for passive immunization against amyloid-β reduces brain amyloid and tau pathologies.

Lathuilière A, Laversenne V, Astolfo A, Kopetzki E, Jacobsen H, Stampanoni M, Bohrmann B, Schneider BL, Aebischer P.

Brain. 2016 May;139(Pt 5):1587-604. doi: 10.1093/brain/aww036. Epub 2016 Mar 8.

PMID:
26956423
27.

Spinal cord stimulation improves forelimb use in an alpha-synuclein animal model of Parkinson's disease.

Brys I, Bobela W, Schneider BL, Aebischer P, Fuentes R.

Int J Neurosci. 2017 Jan;127(1):28-36. Epub 2016 Feb 8.

PMID:
26856727
28.

Regulation of Memory Formation by the Transcription Factor XBP1.

Martínez G, Vidal RL, Mardones P, Serrano FG, Ardiles AO, Wirth C, Valdés P, Thielen P, Schneider BL, Kerr B, Valdés JL, Palacios AG, Inestrosa NC, Glimcher LH, Hetz C.

Cell Rep. 2016 Feb 16;14(6):1382-1394. doi: 10.1016/j.celrep.2016.01.028. Epub 2016 Feb 4.

29.

Severe, multimodal stress exposure induces PTSD-like characteristics in a mouse model of single prolonged stress.

Perrine SA, Eagle AL, George SA, Mulo K, Kohler RJ, Gerard J, Harutyunyan A, Hool SM, Susick LL, Schneider BL, Ghoddoussi F, Galloway MP, Liberzon I, Conti AC.

Behav Brain Res. 2016 Apr 15;303:228-37. doi: 10.1016/j.bbr.2016.01.056. Epub 2016 Jan 25.

PMID:
26821287
30.

In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons.

Mächler P, Wyss MT, Elsayed M, Stobart J, Gutierrez R, von Faber-Castell A, Kaelin V, Zuend M, San Martín A, Romero-Gómez I, Baeza-Lehnert F, Lengacher S, Schneider BL, Aebischer P, Magistretti PJ, Barros LF, Weber B.

Cell Metab. 2016 Jan 12;23(1):94-102. doi: 10.1016/j.cmet.2015.10.010. Epub 2015 Nov 19.

31.

Increased Cortical Gamma-Aminobutyric Acid Precedes Incomplete Extinction of Conditioned Fear and Increased Hippocampal Excitatory Tone in a Mouse Model of Mild Traumatic Brain Injury.

Schneider BL, Ghoddoussi F, Charlton JL, Kohler RJ, Galloway MP, Perrine SA, Conti AC.

J Neurotrauma. 2016 Sep 1;33(17):1614-24. doi: 10.1089/neu.2015.4190. Epub 2016 Mar 18.

PMID:
26529240
32.

Αlpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson's Disease.

Bobela W, Aebischer P, Schneider BL.

Biomolecules. 2015 Oct 16;5(4):2675-700. doi: 10.3390/biom5042675. Review.

33.

Tmc gene therapy restores auditory function in deaf mice.

Askew C, Rochat C, Pan B, Asai Y, Ahmed H, Child E, Schneider BL, Aebischer P, Holt JR.

Sci Transl Med. 2015 Jul 8;7(295):295ra108. doi: 10.1126/scitranslmed.aab1996.

PMID:
26157030
34.

Pathway-specific reorganization of projection neurons in somatosensory cortex during learning.

Chen JL, Margolis DJ, Stankov A, Sumanovski LT, Schneider BL, Helmchen F.

Nat Neurosci. 2015 Aug;18(8):1101-8. doi: 10.1038/nn.4046. Epub 2015 Jun 22.

PMID:
26098757
35.

Chondroitinase gene therapy improves upper limb function following cervical contusion injury.

James ND, Shea J, Muir EM, Verhaagen J, Schneider BL, Bradbury EJ.

Exp Neurol. 2015 Sep;271:131-5. doi: 10.1016/j.expneurol.2015.05.022. Epub 2015 Jun 1.

36.

Encapsulated cellular implants for recombinant protein delivery and therapeutic modulation of the immune system.

Lathuilière A, Mach N, Schneider BL.

Int J Mol Sci. 2015 May 8;16(5):10578-600. doi: 10.3390/ijms160510578. Review.

37.

PGC-1α activity in nigral dopamine neurons determines vulnerability to α-synuclein.

Ciron C, Zheng L, Bobela W, Knott GW, Leone TC, Kelly DP, Schneider BL.

Acta Neuropathol Commun. 2015 Apr 1;3:16. doi: 10.1186/s40478-015-0200-8.

38.

A budding yeast's perspective on aging: the shape I'm in.

Smith J, Wright J, Schneider BL.

Exp Biol Med (Maywood). 2015 Jun;240(6):701-10. doi: 10.1177/1535370215577584. Epub 2015 Mar 27. Review.

39.

Channel-mediated lactate release by K⁺-stimulated astrocytes.

Sotelo-Hitschfeld T, Niemeyer MI, Mächler P, Ruminot I, Lerchundi R, Wyss MT, Stobart J, Fernández-Moncada I, Valdebenito R, Garrido-Gerter P, Contreras-Baeza Y, Schneider BL, Aebischer P, Lengacher S, San Martín A, Le Douce J, Bonvento G, Magistretti PJ, Sepúlveda FV, Weber B, Barros LF.

J Neurosci. 2015 Mar 11;35(10):4168-78. doi: 10.1523/JNEUROSCI.5036-14.2015.

40.

SOD1 silencing in motoneurons or glia rescues neuromuscular function in ALS mice.

Dirren E, Aebischer J, Rochat C, Towne C, Schneider BL, Aebischer P.

Ann Clin Transl Neurol. 2015 Feb;2(2):167-84. doi: 10.1002/acn3.162. Epub 2015 Jan 15.

41.

Adenoviral-mediated expression of G2019S LRRK2 induces striatal pathology in a kinase-dependent manner in a rat model of Parkinson's disease.

Tsika E, Nguyen AP, Dusonchet J, Colin P, Schneider BL, Moore DJ.

Neurobiol Dis. 2015 May;77:49-61. doi: 10.1016/j.nbd.2015.02.019. Epub 2015 Feb 28.

PMID:
25731749
42.

Overview of mouse models of Parkinson's disease.

Bobela W, Zheng L, Schneider BL.

Curr Protoc Mouse Biol. 2014 Sep 3;4(3):121-39. doi: 10.1002/9780470942390.mo140092.

PMID:
25723963
43.

Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS.

Filézac de L'Etang A, Maharjan N, Cordeiro Braña M, Ruegsegger C, Rehmann R, Goswami A, Roos A, Troost D, Schneider BL, Weis J, Saxena S.

Nat Neurosci. 2015 Feb;18(2):227-38. doi: 10.1038/nn.3903. Epub 2015 Jan 5.

PMID:
25559081
44.

Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology.

Yang S, Cacquevel M, Saksida LM, Bussey TJ, Schneider BL, Aebischer P, Melani R, Pizzorusso T, Fawcett JW, Spillantini MG.

Exp Neurol. 2015 Mar;265:48-58. doi: 10.1016/j.expneurol.2014.11.013. Epub 2014 Dec 4.

45.

α-Synuclein-induced dopaminergic neurodegeneration in a rat model of Parkinson's disease occurs independent of ATP13A2 (PARK9).

Daniel G, Musso A, Tsika E, Fiser A, Glauser L, Pletnikova O, Schneider BL, Moore DJ.

Neurobiol Dis. 2015 Jan;73:229-43. doi: 10.1016/j.nbd.2014.10.007. Epub 2014 Oct 18.

PMID:
25461191
46.

Growth, efficiency, and yield of commercial broilers from 1957, 1978, and 2005.

Zuidhof MJ, Schneider BL, Carney VL, Korver DR, Robinson FE.

Poult Sci. 2014 Dec;93(12):2970-82. doi: 10.3382/ps.2014-04291. Epub 2014 Sep 26.

47.

The redundant aminotransferases in lysine and arginine synthesis and the extent of aminotransferase redundancy in Escherichia coli.

Lal PB, Schneider BL, Vu K, Reitzer L.

Mol Microbiol. 2014 Nov;94(4):843-56. doi: 10.1111/mmi.12801. Epub 2014 Oct 12.

48.

The adipocyte differentiation protein APMAP is an endogenous suppressor of Aβ production in the brain.

Mosser S, Alattia JR, Dimitrov M, Matz A, Pascual J, Schneider BL, Fraering PC.

Hum Mol Genet. 2015 Jan 15;24(2):371-82. doi: 10.1093/hmg/ddu449. Epub 2014 Sep 1.

49.

Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation.

Capowski EE, Simonett JM, Clark EM, Wright LS, Howden SE, Wallace KA, Petelinsek AM, Pinilla I, Phillips MJ, Meyer JS, Schneider BL, Thomson JA, Gamm DM.

Hum Mol Genet. 2014 Dec 1;23(23):6332-44. doi: 10.1093/hmg/ddu351. Epub 2014 Jul 9.

50.

A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity.

Dusonchet J, Li H, Guillily M, Liu M, Stafa K, Derada Troletti C, Boon JY, Saha S, Glauser L, Mamais A, Citro A, Youmans KL, Liu L, Schneider BL, Aebischer P, Yue Z, Bandopadhyay R, Glicksman MA, Moore DJ, Collins JJ, Wolozin B.

Hum Mol Genet. 2014 Sep 15;23(18):4887-905. doi: 10.1093/hmg/ddu202. Epub 2014 May 2.

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