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Breast Cancer Index and Prediction of Benefit from Extended Endocrine Therapy in Breast Cancer Patients Treated in the Adjuvant Tamoxifen - To Offer More? (aTTom) Trial.

Bartlett JMS, Sgroi DC, Treuner K, Zhang Y, Ahmed I, Piper T, Salunga R, Brachtel EF, Pirrie SJ, Schnabel CA, Rea DW.

Ann Oncol. 2019 Aug 28. pii: mdz289. doi: 10.1093/annonc/mdz289. [Epub ahead of print]


An equine herpesvirus type 1 (EHV-1) Ab4 open reading frame (ORF)2 deletion mutant provides immunity and protection from EHV-1 infection and disease.

Schnabel CL, Babasyan S, Rollins A, Freer H, Wimer CL, Perkins GA, Raza F, Osterrieder N, Wagner B.

J Virol. 2019 Aug 28. pii: JVI.01011-19. doi: 10.1128/JVI.01011-19. [Epub ahead of print]


C-C motif chemokine ligand (CCL) production in equine peripheral blood mononuclear cells identified by newly generated monoclonal antibodies.

Schnabel CL, Wemette M, Babasyan S, Freer H, Baldwin C, Wagner B.

Vet Immunol Immunopathol. 2018 Oct;204:28-39. doi: 10.1016/j.vetimm.2018.09.003. Epub 2018 Sep 11.


CXCL10 production in equine monocytes is stimulated by interferon-gamma.

Schnabel CL, Babasyan S, Freer H, Wagner B.

Vet Immunol Immunopathol. 2019 Jan;207:25-30. doi: 10.1016/j.vetimm.2018.11.016. Epub 2018 Nov 24.


The deletion of the ORF1 and ORF71 genes reduces virulence of the neuropathogenic EHV-1 strain Ab4 without compromising host immunity in horses.

Wimer CL, Schnabel CL, Perkins G, Babasyan S, Freer H, Stout AE, Rollins A, Osterrieder N, Goodman LB, Glaser A, Wagner B.

PLoS One. 2018 Nov 15;13(11):e0206679. doi: 10.1371/journal.pone.0206679. eCollection 2018.


Discrepancy in risk assessment of hormone receptor positive early-stage breast cancer patients using breast cancer index and recurrence score.

Jerevall PL, Brock J, Palazzo J, Wieczorek T, Misialek M, Guidi AJ, Wu Y, Erlander MG, Zhang Y, Schnabel CA, Goss PE, Horick N, Sgroi DC.

Breast Cancer Res Treat. 2019 Jan;173(2):375-383. doi: 10.1007/s10549-018-5013-6. Epub 2018 Oct 22.


Loss of complex O-glycosylation impairs exocrine pancreatic function and induces MODY8-like diabetes in mice.

Wolters-Eisfeld G, Mercanoglu B, Hofmann BT, Wolpers T, Schnabel C, Harder S, Steffen P, Bachmann K, Steglich B, Schrader J, Gagliani N, Schlüter H, Güngör C, Izbicki JR, Wagener C, Bockhorn M.

Exp Mol Med. 2018 Oct 10;50(10):133. doi: 10.1038/s12276-018-0157-3.


Vitamin D receptor expression and serum 25(OH)D concentration inversely associates with burden of neurofibromas.

Kluwe L, Hagel C, Friedrich RE, Schnabel C, Schön G, Mautner V.

Eur J Cancer Prev. 2019 May;28(3):220-224. doi: 10.1097/CEJ.0000000000000467.


Registration and Fusion of Thermographic and Visual-Light Images in Neurosurgery.

Muller J, Muller J, Chen F, Tetzlaff R, Muller J, Bohl E, Kirsch M, Schnabel C.

IEEE Trans Biomed Circuits Syst. 2018 Dec;12(6):1313-1321. doi: 10.1109/TBCAS.2018.2856407. Epub 2018 Sep 5.


Deletion of the ORF2 gene of the neuropathogenic equine herpesvirus type 1 strain Ab4 reduces virulence while maintaining strong immunogenicity.

Schnabel CL, Wimer CL, Perkins G, Babasyan S, Freer H, Watts C, Rollins A, Osterrieder N, Wagner B.

BMC Vet Res. 2018 Aug 22;14(1):245. doi: 10.1186/s12917-018-1563-4.


In vivo imaging in the oral cavity by endoscopic optical coherence tomography.

Walther J, Schnabel C, Tetschke F, Rosenauer T, Golde J, Ebert N, Baumann M, Hannig C, Koch E.

J Biomed Opt. 2018 Mar;23(7):1-13. doi: 10.1117/1.JBO.23.7.071207.


Sexing of chicken eggs by fluorescence and Raman spectroscopy through the shell membrane.

Galli R, Preusse G, Schnabel C, Bartels T, Cramer K, Krautwald-Junghanns ME, Koch E, Steiner G.

PLoS One. 2018 Feb 23;13(2):e0192554. doi: 10.1371/journal.pone.0192554. eCollection 2018.


La-Ce isotope measurements by multicollector-ICPMS.

Schnabel C, Münker C, Strub E.

J Anal At Spectrom. 2017 Dec 1;32(12):2360-2370. doi: 10.1039/c7ja00256d. Epub 2017 Oct 12.


Comparison of the Performance of 6 Prognostic Signatures for Estrogen Receptor-Positive Breast Cancer: A Secondary Analysis of a Randomized Clinical Trial.

Sestak I, Buus R, Cuzick J, Dubsky P, Kronenwett R, Denkert C, Ferree S, Sgroi D, Schnabel C, Baehner FL, Mallon E, Dowsett M.

JAMA Oncol. 2018 Apr 1;4(4):545-553. doi: 10.1001/jamaoncol.2017.5524.


Ectopic expression of S28A-mutated Histone H3 modulates longevity, stress resistance and cardiac function in Drosophila.

Joos JP, Saadatmand AR, Schnabel C, Viktorinová I, Brand T, Kramer M, Nattel S, Dobrev D, Tomancak P, Backs J, Kleinbongard P, Heusch G, Lorenz K, Koch E, Weber S, El-Armouche A.

Sci Rep. 2018 Feb 13;8(1):2940. doi: 10.1038/s41598-018-21372-3.


Current approaches to avoid the culling of day-old male chicks in the layer industry, with special reference to spectroscopic methods.

Krautwald-Junghanns ME, Cramer K, Fischer B, Förster A, Galli R, Kremer F, Mapesa EU, Meissner S, Preisinger R, Preusse G, Schnabel C, Steiner G, Bartels T.

Poult Sci. 2018 Mar 1;97(3):749-757. doi: 10.3382/ps/pex389. Review.


Geriatric assessment and biomarkers in patients with metastatic breast cancer receiving first-line mono-chemotherapy: Results from the randomized phase III PELICAN trial.

Honecker F, Harbeck N, Schnabel C, Wedding U, Waldenmaier D, Saupe S, Jäger E, Schmidt M, Kreienberg R, Müller L, Otremba B, Dorn J, Warm M, Al-Batran SE, de Wit M; PELICAN investigators.

J Geriatr Oncol. 2018 Mar;9(2):163-169. doi: 10.1016/j.jgo.2017.09.009. Epub 2017 Oct 18.


A Novel Breast Cancer Index for Prediction of Distant Recurrence in HR+ Early-Stage Breast Cancer with One to Three Positive Nodes.

Zhang Y, Schroeder BE, Jerevall PL, Ly A, Nolan H, Schnabel CA, Sgroi DC.

Clin Cancer Res. 2017 Dec 1;23(23):7217-7224. doi: 10.1158/1078-0432.CCR-17-1688. Epub 2017 Sep 22.


Experimental methods for flow and aerosol measurements in human airways and their replicas.

Lizal F, Jedelsky J, Morgan K, Bauer K, Llop J, Cossio U, Kassinos S, Verbanck S, Ruiz-Cabello J, Santos A, Koch E, Schnabel C.

Eur J Pharm Sci. 2018 Feb 15;113:95-131. doi: 10.1016/j.ejps.2017.08.021. Epub 2017 Aug 23. Review.


Variable stretch reduces the pro-inflammatory response of alveolar epithelial cells.

Rentzsch I, Santos CL, Huhle R, Ferreira JMC, Koch T, Schnabel C, Koch E, Pelosi P, Rocco PRM, Gama de Abreu M.

PLoS One. 2017 Aug 15;12(8):e0182369. doi: 10.1371/journal.pone.0182369. eCollection 2017.


Risk stratification with Breast Cancer Index for late distant recurrence in patients with clinically low-risk (T1N0) estrogen receptor-positive breast cancer.

Schroeder B, Zhang Y, Stål O, Fornander T, Brufsky A, Sgroi DC, Schnabel CA.

NPJ Breast Cancer. 2017 Aug 3;3:28. doi: 10.1038/s41523-017-0037-3. eCollection 2017.


Advanced analysis of domain walls in Mg doped LiNbO3 crystals with high resolution OCT.

Kirsten L, Haußmann A, Schnabel C, Schmidt S, Cimalla P, Eng LM, Koch E.

Opt Express. 2017 Jun 26;25(13):14871-14882. doi: 10.1364/OE.25.014871.


Quantification of equine immunoglobulin A in serum and secretions by a fluorescent bead-based assay.

Schnabel CL, Babasyan S, Freer H, Wagner B.

Vet Immunol Immunopathol. 2017 Jun;188:12-20. doi: 10.1016/j.vetimm.2017.04.001. Epub 2017 Apr 10.


Framework for 2D-3D image fusion of infrared thermography with preoperative MRI.

Hoffmann N, Weidner F, Urban P, Meyer T, Schnabel C, Radev Y, Schackert G, Petersohn U, Koch E, Gumhold S, Steiner G, Kirsch M.

Biomed Tech (Berl). 2017 Nov 27;62(6):599-607. doi: 10.1515/bmt-2016-0075.


Performance and prognostic utility of the 92-gene assay in the molecular subclassification of ampullary adenocarcinoma.

Overman MJ, Soifer HS, Schueneman AJ, Ensor J Jr, Adsay V, Saka B, Neishaboori N, Wolff RA, Wang H, Schnabel CA, Varadhachary G.

BMC Cancer. 2016 Aug 22;16:668. doi: 10.1186/s12885-016-2677-3.


Cross-Stratification and Differential Risk by Breast Cancer Index and Recurrence Score in Women with Hormone Receptor-Positive Lymph Node-Negative Early-Stage Breast Cancer.

Sestak I, Zhang Y, Schroeder BE, Schnabel CA, Dowsett M, Cuzick J, Sgroi D.

Clin Cancer Res. 2016 Oct 15;22(20):5043-5048. Epub 2016 Jun 1.


Relapse-free survival of statistically standardized continuous RT-PCR estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2): NCIC CTG MA.14.

Chapman JA, Sgroi DC, Goss PE, Zarella E, Binns S, Zhang Y, Schnabel CA, Erlander MG, Pritchard KI, Han L, Badovinac-Crnjevic T, Shepherd LE, Pollak MN.

Breast Cancer Res Treat. 2016 May;157(1):101-8. doi: 10.1007/s10549-016-3806-z. Epub 2016 Apr 26.


Molecular classification of cancer with the 92-gene assay in cytology and limited tissue samples.

Brachtel EF, Operaña TN, Sullivan PS, Kerr SE, Cherkis KA, Schroeder BE, Dry SM, Schnabel CA.

Oncotarget. 2016 May 10;7(19):27220-31. doi: 10.18632/oncotarget.8449.


Assessment of the prognostic and predictive utility of the Breast Cancer Index (BCI): an NCIC CTG MA.14 study.

Sgroi DC, Chapman JA, Badovinac-Crnjevic T, Zarella E, Binns S, Zhang Y, Schnabel CA, Erlander MG, Pritchard KI, Han L, Shepherd LE, Goss PE, Pollak M.

Breast Cancer Res. 2016 Jan 4;18(1):1. doi: 10.1186/s13058-015-0660-6.


Prospective assessment of the decision-making impact of the Breast Cancer Index in recommending extended adjuvant endocrine therapy for patients with early-stage ER-positive breast cancer.

Sanft T, Aktas B, Schroeder B, Bossuyt V, DiGiovanna M, Abu-Khalaf M, Chung G, Silber A, Hofstatter E, Mougalian S, Epstein L, Hatzis C, Schnabel C, Pusztai L.

Breast Cancer Res Treat. 2015 Dec;154(3):533-41. doi: 10.1007/s10549-015-3631-9. Epub 2015 Nov 14.


Toward a comprehensive interpretation of intravital microscopy images in studies of lung tissue dynamics.

Gaertner M, Schirrmann K, Schnabel C, Meissner S, Kertzscher U, Kirsten L, Koch E.

J Biomed Opt. 2015 Jun;20(6):066009. doi: 10.1117/1.JBO.20.6.066009.


Immune response of healthy horses to DNA constructs formulated with a cationic lipid transfection reagent.

Schnabel CL, Steinig P, Koy M, Schuberth HJ, Juhls C, Oswald D, Wittig B, Willenbrock S, Murua Escobar H, Pfarrer C, Wagner B, Jaehnig P, Moritz A, Feige K, Cavalleri JM.

BMC Vet Res. 2015 Jun 23;11:140. doi: 10.1186/s12917-015-0452-3.


Influences of age and sex on leukocytes of healthy horses and their ex vivo cytokine release.

Schnabel CL, Steinig P, Schuberth HJ, Koy M, Wagner B, Wittig B, Juhls C, Willenbrock S, Murua Escobar H, Jaehnig P, Feige K, Cavalleri JM.

Vet Immunol Immunopathol. 2015 May 15;165(1-2):64-74. doi: 10.1016/j.vetimm.2015.02.011. Epub 2015 Mar 6.


Ex vivo 4D visualization of aortic valve dynamics in a murine model with optical coherence tomography.

Schnabel C, Jannasch A, Faak S, Waldow T, Koch E.

Biomed Opt Express. 2014 Nov 7;5(12):4201-12. doi: 10.1364/BOE.5.004201. eCollection 2014 Dec 1.


Heart valve stenosis in laser spotlights: insights into a complex disease.

Büttner P, Galli R, Jannasch A, Schnabel C, Waldow T, Koch E.

Clin Hemorheol Microcirc. 2014;58(1):65-75. doi: 10.3233/CH-141882.


Health economic analysis of Breast Cancer Index in patients with ER+, LN- breast cancer.

Gustavsen G, Schroeder B, Kennedy P, Pothier KC, Erlander MG, Schnabel CA, Ali H.

Am J Manag Care. 2014 Aug 1;20(8):e302-10.


Thrombin generation in a patient with an acquired high-titre factor V inhibitor.

Schmidt DE, Steinhagen F, Schnabel C, Spath B, Holstein K, Fiedler W, Bokemeyer C, Renné T, Langer F.

Blood Coagul Fibrinolysis. 2015 Jan;26(1):81-7. doi: 10.1097/MBC.0000000000000181.


Cost effectiveness of a 92-gene assay for the diagnosis of metastatic cancer.

Bentley TG, Schroeder BE, Schnabel CA, Erlander MG, Hsiao WC, Ortendahl JD, Broder MS.

J Med Econ. 2014 Aug;17(8):527-37. doi: 10.3111/13696998.2014.909817. Epub 2014 May 14.


Differences of 25-hydroxyvitamin D3 concentrations in children and adults with neurofibromatosis type 1.

Schnabel C, Dahm S, Streichert T, Thierfelder W, Kluwe L, Mautner VF.

Clin Biochem. 2014 May;47(7-8):560-3. doi: 10.1016/j.clinbiochem.2014.02.020. Epub 2014 Mar 6.


Total liquid ventilation: a new approach to improve 3D OCT image quality of alveolar structures in lung tissue.

Schnabel C, Gaertner M, Kirsten L, Meissner S, Koch E.

Opt Express. 2013 Dec 30;21(26):31782-8. doi: 10.1364/OE.21.031782.


Relevant bleeding diathesis due to acquired factor XIII deficiency.

Janning M, Holstein K, Spath B, Schnabel C, Bannas P, Bokemeyer C, Langer F.

Hamostaseologie. 2013;33 Suppl 1:S50-4.


Efficacy and selectivity of nilotinib on NF1-associated tumors in vitro.

Jiang W, Schnabel C, Spyra M, Mautner VF, Friedrich RE, Hagel C, Manley PW, Kluwe L.

J Neurooncol. 2014 Jan;116(2):231-6. doi: 10.1007/s11060-013-1295-z. Epub 2013 Oct 31.


Evaluation of the reactivity of commercially available monoclonal antibodies with equine cytokines.

Schnabel CL, Wagner S, Wagner B, Durán MC, Babasyan S, Nolte I, Pfarrer C, Feige K, Murua Escobar H, Cavalleri JM.

Vet Immunol Immunopathol. 2013 Nov 15;156(1-2):1-19. doi: 10.1016/j.vetimm.2013.09.012. Epub 2013 Sep 25.


3D Optical Coherence Tomography for Investigating Alveolar Structures During Total Liquid Ventilation.

Schnabel C, Gaertner M, Meissner S, Koch E.

Biomed Tech (Berl). 2013 Aug;58 Suppl 1. pii: /j/bmte.2013.58.issue-s1-L/bmt-2013-4286/bmt-2013-4286.xml. doi: 10.1515/bmt-2013-4286. Epub 2013 Sep 7. No abstract available.


Prediction of late distant recurrence in patients with oestrogen-receptor-positive breast cancer: a prospective comparison of the breast-cancer index (BCI) assay, 21-gene recurrence score, and IHC4 in the TransATAC study population.

Sgroi DC, Sestak I, Cuzick J, Zhang Y, Schnabel CA, Schroeder B, Erlander MG, Dunbier A, Sidhu K, Lopez-Knowles E, Goss PE, Dowsett M.

Lancet Oncol. 2013 Oct;14(11):1067-1076. doi: 10.1016/S1470-2045(13)70387-5. Epub 2013 Sep 12. Erratum in: Lancet Oncol. 2018 Apr;19(4):e184.


A 92-gene cancer classifier predicts the site of origin for neuroendocrine tumors.

Kerr SE, Schnabel CA, Sullivan PS, Zhang Y, Huang VJ, Erlander MG, Brachtel EF, Dry SM.

Mod Pathol. 2014 Jan;27(1):44-54. doi: 10.1038/modpathol.2013.105. Epub 2013 Jul 12.


Rapid thinning of the Late Pleistocene Patagonian Ice Sheet followed migration of the Southern Westerlies.

Boex J, Fogwill C, Harrison S, Glasser NF, Hein A, Schnabel C, Xu S.

Sci Rep. 2013;3:2118. doi: 10.1038/srep02118.


Prediction of late disease recurrence and extended adjuvant letrozole benefit by the HOXB13/IL17BR biomarker.

Sgroi DC, Carney E, Zarrella E, Steffel L, Binns SN, Finkelstein DM, Szymonifka J, Bhan AK, Shepherd LE, Zhang Y, Schnabel CA, Erlander MG, Ingle JN, Porter P, Muss HB, Pritchard KI, Tu D, Rimm DL, Goss PE.

J Natl Cancer Inst. 2013 Jul 17;105(14):1036-42. doi: 10.1093/jnci/djt146. Epub 2013 Jun 28.


Breast cancer index identifies early-stage estrogen receptor-positive breast cancer patients at risk for early- and late-distant recurrence.

Zhang Y, Schnabel CA, Schroeder BE, Jerevall PL, Jankowitz RC, Fornander T, Stål O, Brufsky AM, Sgroi D, Erlander MG.

Clin Cancer Res. 2013 Aug 1;19(15):4196-205. doi: 10.1158/1078-0432.CCR-13-0804. Epub 2013 Jun 11.


Development and validation of a 32-gene prognostic index for prostate cancer progression.

Wu CL, Schroeder BE, Ma XJ, Cutie CJ, Wu S, Salunga R, Zhang Y, Kattan MW, Schnabel CA, Erlander MG, McDougal WS.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6121-6. doi: 10.1073/pnas.1215870110. Epub 2013 Mar 26.

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