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Items: 50

1.

Quantitative analysis of ATM phosphorylation in lymphocytes.

Bakkenist CJ, Czambel RK, Lin Y, Yates NA, Zeng X, Shogan J, Schmitz JC.

DNA Repair (Amst). 2019 Aug;80:1-7. doi: 10.1016/j.dnarep.2019.06.002. Epub 2019 Jun 4.

PMID:
31176958
2.

Targeting colon cancer with the novel STAT3 inhibitor bruceantinol.

Wei N, Li J, Fang C, Chang J, Xirou V, Syrigos NK, Marks BJ, Chu E, Schmitz JC.

Oncogene. 2019 Mar;38(10):1676-1687. doi: 10.1038/s41388-018-0547-y. Epub 2018 Oct 22.

PMID:
30348989
3.

ATM Is Required for the Repair of Oxaliplatin-Induced DNA Damage in Colorectal Cancer.

Bakkenist CJ, Lee JJ, Schmitz JC.

Clin Colorectal Cancer. 2018 Dec;17(4):255-257. doi: 10.1016/j.clcc.2018.09.001. Epub 2018 Sep 13. No abstract available.

4.

Molecular subtypes of colorectal cancer in pre-clinical models show differential response to targeted therapies: Treatment implications beyond KRAS mutations.

Pal R, Wei N, Song N, Wu S, Kim RS, Wang Y, Gavin PG, Lucas PC, Srinivasan A, Allegra CJ, Jacobs SA, Paik S, Schmitz JC, Pogue-Geile KL.

PLoS One. 2018 Aug 17;13(8):e0200836. doi: 10.1371/journal.pone.0200836. eCollection 2018.

5.

Psychometric properties of the Child and Adolescent Mindfulness Measure (CAMM) in racial minority adolescents from low-income environments.

Prenoveau JM, Papadakis AA, Schmitz JCS, Hirsch EL, Dariotis JK, Mendelson T.

Psychol Assess. 2018 Oct;30(10):1395-1400. doi: 10.1037/pas0000630. Epub 2018 Jul 26.

PMID:
30047745
6.

Herbal formula Huang Qin Ge Gen Tang enhances 5-fluorouracil antitumor activity through modulation of the E2F1/TS pathway.

Liu H, Liu H, Zhou Z, Parise RA, Chu E, Schmitz JC.

Cell Commun Signal. 2018 Feb 20;16(1):7. doi: 10.1186/s12964-018-0218-1.

7.

Phase I study of veliparib in combination with gemcitabine.

Stoller R, Schmitz JC, Ding F, Puhalla S, Belani CP, Appleman L, Lin Y, Jiang Y, Almokadem S, Petro D, Holleran J, Kiesel BF, Ken Czambel R, Carneiro BA, Kontopodis E, Hershberger PA, Rachid M, Chen A, Chu E, Beumer JH.

Cancer Chemother Pharmacol. 2017 Sep;80(3):631-643. doi: 10.1007/s00280-017-3409-3. Epub 2017 Aug 2.

8.

[Pre- and perinatal risk factors in autism spectrum disorder and attention deficit/hyperactivity disorder].

Schmitz JC, Cholemkery H, Medda J, Freitag CM.

Z Kinder Jugendpsychiatr Psychother. 2017;45(3):209-217. doi: 10.1024/1422-4917/a000507. Epub 2017 Jan 27. German.

PMID:
28128013
9.

Pharmacodynamic analyses in a multi-laboratory network: lessons from the poly(ADP-ribose) assay.

Ferry-Galow KV, Ji J, Kinders RJ, Zhang Y, Czambel RK, Schmitz JC, Herzog J, Evrard YA, Parchment RE.

Semin Oncol. 2016 Aug;43(4):492-500. doi: 10.1053/j.seminoncol.2016.06.007. Epub 2016 Jun 15.

PMID:
27663481
10.

ATM serine-1981 phosphorylation is a plausible biomarker.

Bakkenist CJ, Beumer JH, Schmitz JC.

Cell Cycle. 2015;14(20):3207-8. doi: 10.1080/15384101.2015.1084205. No abstract available.

11.

Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells.

Wu S, Guo Z, Hopkins CD, Wei N, Chu E, Wipf P, Schmitz JC.

Oncotarget. 2015 Dec 1;6(38):40866-79. doi: 10.18632/oncotarget.5885.

12.

A quasi-quantitative dual multiplexed immunoblot method to simultaneously analyze ATM and H2AX Phosphorylation in human peripheral blood mononuclear cells.

Bakkenist CJ, Czambel RK, Hershberger PA, Tawbi H, Beumer JH, Schmitz JC.

Oncoscience. 2015 May 14;2(5):542-54. eCollection 2015.

13.
14.

Clove extract inhibits tumor growth and promotes cell cycle arrest and apoptosis.

Liu H, Schmitz JC, Wei J, Cao S, Beumer JH, Strychor S, Cheng L, Liu M, Wang C, Wu N, Zhao X, Zhang Y, Liao J, Chu E, Lin X.

Oncol Res. 2014;21(5):247-59. doi: 10.3727/096504014X13946388748910.

15.

Protein kinase d as a potential chemotherapeutic target for colorectal cancer.

Wei N, Chu E, Wipf P, Schmitz JC.

Mol Cancer Ther. 2014 May;13(5):1130-41. doi: 10.1158/1535-7163.MCT-13-0880. Epub 2014 Mar 14.

16.

Phase I trial of carboplatin and etoposide in combination with panobinostat in patients with lung cancer.

Tarhini AA, Zahoor H, McLaughlin B, Gooding WE, Schmitz JC, Siegfried JM, Socinski MA, Argiris A.

Anticancer Res. 2013 Oct;33(10):4475-81.

17.

Radiation therapy induces the DNA damage response in peripheral blood.

Bakkenist CJ, Czambel RK, Clump DA, Greenberger JS, Beumer JH, Schmitz JC.

Oncotarget. 2013 Aug;4(8):1143-8.

18.

Development of modified siRNA molecules incorporating 5-fluoro-2'-deoxyuridine residues to enhance cytotoxicity.

Wu SY, Chen TM, Gmeiner WH, Chu E, Schmitz JC.

Nucleic Acids Res. 2013 Apr;41(8):4650-9. doi: 10.1093/nar/gkt120. Epub 2013 Feb 28.

19.

Identification of Streptomyces sp. nov. WH26 producing cytotoxic compounds isolated from marine solar saltern in China.

Liu H, Xiao L, Wei J, Schmitz JC, Liu M, Wang C, Cheng L, Wu N, Chen L, Zhang Y, Lin X.

World J Microbiol Biotechnol. 2013 Jul;29(7):1271-8. doi: 10.1007/s11274-013-1290-8. Epub 2013 Feb 19.

PMID:
23420111
20.

Intermedin is overexpressed in hepatocellular carcinoma and regulates cell proliferation and survival.

Guo X, Schmitz JC, Kenney BC, Uchio EM, Kulkarni S, Cha CH.

Cancer Sci. 2012 Aug;103(8):1474-80. doi: 10.1111/j.1349-7006.2012.02341.x. Epub 2012 Jul 11.

21.

Pigment epithelium-derived factor regulates early pancreatic fibrotic responses and suppresses the profibrotic cytokine thrombospondin-1.

Schmitz JC, Protiva P, Gattu AK, Utsumi T, Iwakiri Y, Neto AG, Quinn M, Cornwell ML, Fitchev P, Lugea A, Crawford SE, Chung C.

Am J Pathol. 2011 Dec;179(6):2990-9. doi: 10.1016/j.ajpath.2011.08.009. Epub 2011 Sep 28.

22.

Total synthesis of (-)-CP2-disorazole C1.

Hopkins CD, Schmitz JC, Chu E, Wipf P.

Org Lett. 2011 Aug 5;13(15):4088-91. doi: 10.1021/ol2015994. Epub 2011 Jul 8.

23.

The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer.

Chung C, Mader CC, Schmitz JC, Atladottir J, Fitchev P, Cornwell ML, Koleske AJ, Crawford SE, Gorelick F.

Lab Invest. 2011 May;91(5):732-43. doi: 10.1038/labinvest.2011.8. Epub 2011 Feb 21.

24.
25.

C-Raf is associated with disease progression and cell proliferation in a subset of melanomas.

Jilaveanu LB, Zito CR, Aziz SA, Conrad PJ, Schmitz JC, Sznol M, Camp RL, Rimm DL, Kluger HM.

Clin Cancer Res. 2009 Sep 15;15(18):5704-13. doi: 10.1158/1078-0432.CCR-09-0198. Epub 2009 Sep 8.

26.

Identification of a cis-acting element of human dihydrofolate reductase mRNA.

Tai N, Schmitz JC, Chen TM, O'Neill MB, Chu E.

Biochem Biophys Res Commun. 2008 May 9;369(3):795-800. Epub 2007 Sep 21.

PMID:
18045573
27.

Regulation of p53 expression in response to 5-fluorouracil in human cancer RKO cells.

Ju J, Schmitz JC, Song B, Kudo K, Chu E.

Clin Cancer Res. 2007 Jul 15;13(14):4245-51.

28.

Short interfering RNA-mediated gene silencing of vascular endothelial growth factor: effects on cellular proliferation in colon cancer cells.

Mulkeen AL, Silva T, Yoo PS, Schmitz JC, Uchio E, Chu E, Cha C.

Arch Surg. 2006 Apr;141(4):367-74; discussion 374.

PMID:
16618894
29.
30.

Translational autoregulation of thymidylate synthase and dihydrofolate reductase.

Tai N, Schmitz JC, Liu J, Lin X, Bailly M, Chen TM, Chu E.

Front Biosci. 2004 Sep 1;9:2521-6. Review.

PMID:
15353304
32.
33.

Thymidylate synthase inhibitors as anticancer agents: from bench to bedside.

Chu E, Callender MA, Farrell MP, Schmitz JC.

Cancer Chemother Pharmacol. 2003 Jul;52 Suppl 1:S80-9. Epub 2003 Jun 18. Review.

PMID:
12819937
34.

Thymidylate synthase: a critical target for cancer chemotherapy.

Rose MG, Farrell MP, Schmitz JC.

Clin Colorectal Cancer. 2002 Feb;1(4):220-9. Review.

PMID:
12450420
35.
36.

Thymidylate synthase as a translational regulator of cellular gene expression.

Liu J, Schmitz JC, Lin X, Tai N, Yan W, Farrell M, Bailly M, Chen Tm, Chu E.

Biochim Biophys Acta. 2002 Jul 18;1587(2-3):174-82. Review.

37.

Translational regulation as a novel mechanism for the development of cellular drug resistance.

Schmitz JC, Liu J, Lin X, Chen TM, Yan W, Tai N, Gollerkeri A, Chu E.

Cancer Metastasis Rev. 2001;20(1-2):33-41. Review.

PMID:
11831645
38.

Effect of 2'-O-methyl antisense ORNs on expression of thymidylate synthase in human colon cancer RKO cells.

Schmitz JC, Yu D, Agrawal S, Chu E.

Nucleic Acids Res. 2001 Jan 15;29(2):415-22.

39.

Accumulation of plasma reduced folates after folic acid administration.

Priest DG, Schmitz JC, Bunni MA.

Semin Oncol. 1999 Apr;26(2 Suppl 6):38-41.

PMID:
10598553
40.

An immunoprecipitation-RNA:rPCR method for the in vivo isolation of ribonucleoprotein complexes.

Chu E, Schmitz JC, Ju J, Copur SM.

Methods Mol Biol. 1999;118:265-74. No abstract available.

PMID:
10549529
41.

Repression of human thymidylate synthase mRNA translation by antisense 2'-O-methyl oligoribonucleotides.

Schmitz JC, Agrawal S, Chu E.

Antisense Nucleic Acid Drug Dev. 1998 Oct;8(5):371-8.

PMID:
9826264
42.

Impact of schedule on leucovorin potentiation of fluorouracil antitumor activity in dietary folic acid deplete mice.

Raghunathan K, Schmitz JC, Priest DG.

Biochem Pharmacol. 1997 Apr 25;53(8):1197-202.

PMID:
9175725
43.

Disposition of leucovorin and its metabolites in dietary folic acid-deplete mice - comparison between tumor, liver, and plasma.

Raghunathan K, Schmitz JC, Priest DG.

Cancer Chemother Pharmacol. 1997;40(2):126-30.

PMID:
9182833
44.

Impact of dietary folic acid on reduced folates in mouse plasma and tissues. Relationship to dideazatetrahydrofolate sensitivity.

Schmitz JC, Grindey GB, Schultz RM, Priest DG.

Biochem Pharmacol. 1994 Jul 19;48(2):319-25.

PMID:
8053927
45.

Disposition of folic acid and its metabolites: a comparison with leucovorin.

Schmitz JC, Stuart RK, Priest DG.

Clin Pharmacol Ther. 1994 May;55(5):501-8.

PMID:
8181194
46.

Folate metabolites as modulators of antitumor drug activity.

Priest DG, Schmitz JC, Bunni MA.

Adv Exp Med Biol. 1993;338:693-8. Review. No abstract available.

PMID:
8304208
47.

Leucovorin as a prodrug.

Priest DG, Schmitz JC, Walle T.

Adv Exp Med Biol. 1993;339:31-40; discussion 41-2. No abstract available.

PMID:
8178726
48.

Pharmacokinetics of leucovorin metabolites in human plasma as a function of dose administered orally and intravenously.

Priest DG, Schmitz JC, Bunni MA, Stuart RK.

J Natl Cancer Inst. 1991 Dec 18;83(24):1806-12.

PMID:
1744924
49.

A sensitive radioenzymatic assay for (S)-5-formyltetrahydrofolate.

Priest DG, Bunni MA, Romero-Fredes LR, Schmitz JC, Whiteley JM.

Anal Biochem. 1991 Aug 1;196(2):284-9.

PMID:
1776677
50.

Hemolysis of rabbit erythrocytes in the presence of copper ions. Inhibition by albumin and ceruloplasmin.

Caffrey JM Jr, Smith HA, Schmitz JC, Merchant A, Frieden E.

Biol Trace Elem Res. 1990 Apr;25(1):11-9.

PMID:
1696107

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