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Items: 1 to 50 of 72

1.

T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant.

Chapuis AG, Egan DN, Bar M, Schmitt TM, McAfee MS, Paulson KG, Voillet V, Gottardo R, Ragnarsson GB, Bleakley M, Yeung CC, Muhlhauser P, Nguyen HN, Kropp LA, Castelli L, Wagener F, Hunter D, Lindberg M, Cohen K, Seese A, McElrath MJ, Duerkopp N, Gooley TA, Greenberg PD.

Nat Med. 2019 Jul;25(7):1064-1072. doi: 10.1038/s41591-019-0472-9. Epub 2019 Jun 24.

PMID:
31235963
2.

Subclinical Cognitive Impairment and Listing for Kidney Transplantation.

Gupta A, Montgomery RN, Bedros V, Lesko J, Mahnken JD, Chakraborty S, Drew D, Klein JA, Thomas TS, Ilahe A, Budhiraja P, Brooks WM, Schmitt TM, Sarnak MJ, Burns JM, Cibrik DM.

Clin J Am Soc Nephrol. 2019 Apr 5;14(4):567-575. doi: 10.2215/CJN.11010918. Epub 2019 Mar 19.

PMID:
30890576
3.

Comparison of T Cell Activities Mediated by Human TCRs and CARs That Use the Same Recognition Domains.

Harris DT, Hager MV, Smith SN, Cai Q, Stone JD, Kruger P, Lever M, Dushek O, Schmitt TM, Greenberg PD, Kranz DM.

J Immunol. 2018 Feb 1;200(3):1088-1100. doi: 10.4049/jimmunol.1700236. Epub 2017 Dec 29.

4.

Generation of higher affinity T cell receptors by antigen-driven differentiation of progenitor T cells in vitro.

Schmitt TM, Aggen DH, Ishida-Tsubota K, Ochsenreither S, Kranz DM, Greenberg PD.

Nat Biotechnol. 2017 Dec;35(12):1188-1195. doi: 10.1038/nbt.4004. Epub 2017 Nov 6.

5.

A CD200R-CD28 fusion protein appropriates an inhibitory signal to enhance T-cell function and therapy of murine leukemia.

Oda SK, Daman AW, Garcia NM, Wagener F, Schmitt TM, Tan X, Chapuis AG, Greenberg PD.

Blood. 2017 Nov 30;130(22):2410-2419. doi: 10.1182/blood-2017-04-777052. Epub 2017 Oct 17.

6.

The miR-106a~363Xpcl1 miRNA cluster induces murine T cell lymphoma despite transcriptional activation of the p27Kip1 cell cycle inhibitor.

Kuppers DA, Schmitt TM, Hwang HC, Samraj L, Clurman BE, Fero ML.

Oncotarget. 2017 Apr 7;8(31):50680-50691. doi: 10.18632/oncotarget.16932. eCollection 2017 Aug 1.

7.

Tracking the Fate and Origin of Clinically Relevant Adoptively Transferred CD8+ T Cells In Vivo.

Chapuis AG, Desmarais C, Emerson R, Schmitt TM, Shibuya K, Lai I, Wagener F, Chou J, Roberts IM, Coffey DG, Warren E, Robbins H, Greenberg PD, Yee C.

Sci Immunol. 2017 Feb;2(8). pii: eaal2568. doi: 10.1126/sciimmunol.aal2568. Epub 2017 Feb 24.

8.

Development of Third-generation Cocal Envelope Producer Cell Lines for Robust Lentiviral Gene Transfer into Hematopoietic Stem Cells and T-cells.

Humbert O, Gisch DW, Wohlfahrt ME, Adams AB, Greenberg PD, Schmitt TM, Trobridge GD, Kiem HP.

Mol Ther. 2016 Aug;24(7):1237-46. doi: 10.1038/mt.2016.70. Epub 2016 Apr 8.

9.

Pre-transplant portal vein thrombosis is an independent risk factor for graft loss due to hepatic artery thrombosis in liver transplant recipients.

Stine JG, Pelletier SJ, Schmitt TM, Porte RJ, Northup PG.

HPB (Oxford). 2016 Mar;18(3):279-86. doi: 10.1016/j.hpb.2015.10.008. Epub 2015 Dec 10.

10.

Increased hepatic receptor interacting protein kinase 3 expression due to impaired proteasomal functions contributes to alcohol-induced steatosis and liver injury.

Wang S, Ni HM, Dorko K, Kumer SC, Schmitt TM, Nawabi A, Komatsu M, Huang H, Ding WX.

Oncotarget. 2016 Apr 5;7(14):17681-98. doi: 10.18632/oncotarget.6893.

11.

Lack of Direct Cytotoxicity of Extracellular ATP against Hepatocytes: Role in the Mechanism of Acetaminophen Hepatotoxicity.

Xie Y, Woolbright BL, Kos M, McGill MR, Dorko K, Kumer SC, Schmitt TM, Jaeschke H.

J Clin Transl Res. 2015;1(2):100-106. Epub 2015 Sep 30.

12.

T Cells Engineered against a Native Antigen Can Surmount Immunologic and Physical Barriers to Treat Pancreatic Ductal Adenocarcinoma.

Stromnes IM, Schmitt TM, Hulbert A, Brockenbrough JS, Nguyen H, Cuevas C, Dotson AM, Tan X, Hotes JL, Greenberg PD, Hingorani SR.

Cancer Cell. 2015 Nov 9;28(5):638-652. doi: 10.1016/j.ccell.2015.09.022. Epub 2015 Oct 29.

13.

New Strategies in Engineering T-cell Receptor Gene-Modified T cells to More Effectively Target Malignancies.

Schmitt TM, Stromnes IM, Chapuis AG, Greenberg PD.

Clin Cancer Res. 2015 Dec 1;21(23):5191-7. doi: 10.1158/1078-0432.CCR-15-0860. Epub 2015 Oct 13. Review.

14.

Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes.

Xie Y, McGill MR, Du K, Dorko K, Kumer SC, Schmitt TM, Ding WX, Jaeschke H.

Toxicol Appl Pharmacol. 2015 Dec 1;289(2):213-22. doi: 10.1016/j.taap.2015.09.022. Epub 2015 Sep 30.

15.

Lack of direct cytotoxicity of extracellular ATP against hepatocytes: role in the mechanism of acetaminophen hepatotoxicity.

Xie Y, Woolbright BL, Kos M, McGill MR, Dorko K, Kumer SC, Schmitt TM, Jaeschke H.

J Clin Transl Res. 2015 Sep 30;1(2):1-7. eCollection 2015 Sep 30.

16.

Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis.

Woolbright BL, Dorko K, Antoine DJ, Clarke JI, Gholami P, Li F, Kumer SC, Schmitt TM, Forster J, Fan F, Jenkins RE, Park BK, Hagenbuch B, Olyaee M, Jaeschke H.

Toxicol Appl Pharmacol. 2015 Mar 15;283(3):168-77. doi: 10.1016/j.taap.2015.01.015. Epub 2015 Jan 28.

17.

Late-onset renal vein thrombosis: A case report and review of the literature.

Hogan JL, Rosenthal SJ, Yarlagadda SG, Jones JA, Schmitt TM, Kumer SC, Kaplan B, Deas SL, Nawabi AM.

Int J Surg Case Rep. 2015;6C:73-6. doi: 10.1016/j.ijscr.2014.09.027. Epub 2014 Nov 21.

18.

Combined transmesenteric and transhepatic recanalization of chronic portal and mesenteric vein occlusion to treat bleeding duodenal varices.

Sabri SS, Caldwell SH, Kumer SC, Schmitt TM, Maluf DG, Angle JF, Saad WE.

J Vasc Interv Radiol. 2014 Aug;25(8):1295-9. doi: 10.1016/j.jvir.2013.11.021.

PMID:
25085062
19.

Mechanisms of acetaminophen-induced cell death in primary human hepatocytes.

Xie Y, McGill MR, Dorko K, Kumer SC, Schmitt TM, Forster J, Jaeschke H.

Toxicol Appl Pharmacol. 2014 Sep 15;279(3):266-74. doi: 10.1016/j.taap.2014.05.010. Epub 2014 Jun 3.

20.

Re-adapting T cells for cancer therapy: from mouse models to clinical trials.

Stromnes IM, Schmitt TM, Chapuis AG, Hingorani SR, Greenberg PD.

Immunol Rev. 2014 Jan;257(1):145-64. doi: 10.1111/imr.12141. Review.

21.

Donor risk index predicts graft failure reliably but not post-transplant infections.

Rosenberger LH, Gillen JR, Hranjec T, Stokes JB, Brayman KL, Kumer SC, Schmitt TM, Sawyer RG.

Surg Infect (Larchmt). 2014 Apr;15(2):94-8. doi: 10.1089/sur.2013.035. Epub 2013 Nov 27.

22.

Hepatolithiasis after Hepaticojejunostomy: Ascaris lumbricoides in the biliary tract.

Heimes JK, Waller S, Olyee M, Schmitt TM.

Surg Infect (Larchmt). 2013 Oct;14(5):470-2. doi: 10.1089/sur.2012.115. Epub 2013 Aug 30.

PMID:
23991626
23.

Enhanced-affinity murine T-cell receptors for tumor/self-antigens can be safe in gene therapy despite surpassing the threshold for thymic selection.

Schmitt TM, Aggen DH, Stromnes IM, Dossett ML, Richman SA, Kranz DM, Greenberg PD.

Blood. 2013 Jul 18;122(3):348-56. doi: 10.1182/blood-2013-01-478164. Epub 2013 May 14.

24.

Transferred WT1-reactive CD8+ T cells can mediate antileukemic activity and persist in post-transplant patients.

Chapuis AG, Ragnarsson GB, Nguyen HN, Chaney CN, Pufnock JS, Schmitt TM, Duerkopp N, Roberts IM, Pogosov GL, Ho WY, Ochsenreither S, Wölfl M, Bar M, Radich JP, Yee C, Greenberg PD.

Sci Transl Med. 2013 Feb 27;5(174):174ra27. doi: 10.1126/scitranslmed.3004916.

25.

Impact of stem cell marker expression on recurrence of TACE-treated hepatocellular carcinoma post liver transplantation.

Zeng Z, Ren J, O'Neil M, Zhao J, Bridges B, Cox J, Abdulkarim B, Schmitt TM, Kumer SC, Weinman SA.

BMC Cancer. 2012 Dec 7;12:584. doi: 10.1186/1471-2407-12-584.

26.

Abrogation of SRC homology region 2 domain-containing phosphatase 1 in tumor-specific T cells improves efficacy of adoptive immunotherapy by enhancing the effector function and accumulation of short-lived effector T cells in vivo.

Stromnes IM, Fowler C, Casamina CC, Georgopolos CM, McAfee MS, Schmitt TM, Tan X, Kim TD, Choi I, Blattman JN, Greenberg PD.

J Immunol. 2012 Aug 15;189(4):1812-25. doi: 10.4049/jimmunol.1200552. Epub 2012 Jul 13.

27.

Quantifying increased hepatic arterial flow with test balloon occlusion of the splenic artery in liver transplant recipients with suspected splenic steal syndrome: quantitative digitally subtracted angiography correlation with arterial Doppler parameters.

Saad WE, Anderson CL, Kowarschik M, Turba UC, Schmitt TM, Kumer SC, Matsumoto AH, Angle JF.

Vasc Endovascular Surg. 2012 Jul;46(5):384-92. doi: 10.1177/1538574412449394. Epub 2012 Jun 6.

PMID:
22677799
28.

Elderly recipients of hepatitis C positive renal allografts can quickly develop liver disease.

Flohr TR, Bonatti H, Hranjec T, Keith DS, Lobo PI, Kumer SC, Schmitt TM, Sawyer RG, Pruett TL, Roberts JP, Brayman KL.

J Surg Res. 2012 Aug;176(2):629-38. doi: 10.1016/j.jss.2011.10.028. Epub 2011 Nov 19.

29.

Regional variability in symptom-based MELD exceptions: a response to organ shortage?

Argo CK, Stukenborg GJ, Schmitt TM, Kumer SC, Berg CL, Northup PG.

Am J Transplant. 2011 Nov;11(11):2353-61. doi: 10.1111/j.1600-6143.2011.03738.x.

30.

Sorafenib therapy for hepatocellular carcinoma prior to liver transplant is associated with increased complications after transplant.

Truesdale AE, Caldwell SH, Shah NL, Argo CK, Al-Osaimi AM, Schmitt TM, Northup PG.

Transpl Int. 2011 Oct;24(10):991-8. doi: 10.1111/j.1432-2277.2011.01299.x. Epub 2011 Jul 21.

31.

Single-chain VαVβ T-cell receptors function without mispairing with endogenous TCR chains.

Aggen DH, Chervin AS, Schmitt TM, Engels B, Stone JD, Richman SA, Piepenbrink KH, Baker BM, Greenberg PD, Schreiber H, Kranz DM.

Gene Ther. 2012 Apr;19(4):365-74. doi: 10.1038/gt.2011.104. Epub 2011 Jul 14.

32.

Closure of ascites leaks with fibrin glue injection in patients with end-stage liver disease.

Sadik KW, Laibstain S, Northup PG, Kashmer D, Schmitt TM, Bonatti HJ.

J Laparoendosc Adv Surg Tech A. 2011 Sep;21(7):609-14. doi: 10.1089/lap.2010.0476. Epub 2011 May 25.

PMID:
21612447
33.

Endovascular therapy for hepatic artery stenosis and thrombosis following liver transplantation.

Sabri SS, Saad WE, Schmitt TM, Turba UC, Kumer SC, Park AW, Matsumoto AH, Angle JF.

Vasc Endovascular Surg. 2011 Jul;45(5):447-52. doi: 10.1177/1538574411407088. Epub 2011 May 13.

PMID:
21571780
34.

Opposite effects of endogenous peptide-MHC class I on T cell activity in the presence and absence of CD8.

Stone JD, Aggen DH, Chervin AS, Narayanan S, Schmitt TM, Greenberg PD, Kranz DM.

J Immunol. 2011 May 1;186(9):5193-200. doi: 10.4049/jimmunol.1003755. Epub 2011 Mar 30.

35.

Liver transplantation for T3 lesions has higher waiting list mortality but similar survival compared to T1 and T2 lesions.

Schmitt TM, Kumer SC, Shah N, Argo CK, Northup PG.

Ann Hepatol. 2010 Oct-Dec;9(4):390-6.

36.

The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor.

Hudecek M, Schmitt TM, Baskar S, Lupo-Stanghellini MT, Nishida T, Yamamoto TN, Bleakley M, Turtle CJ, Chang WC, Greisman HA, Wood B, Maloney DG, Jensen MC, Rader C, Riddell SR.

Blood. 2010 Nov 25;116(22):4532-41. doi: 10.1182/blood-2010-05-283309. Epub 2010 Aug 11.

37.

Liver allografts from hepatitis C positive donors can offer good outcomes in hepatitis C positive recipients: a US National Transplant Registry analysis.

Northup PG, Argo CK, Nguyen DT, McBride MA, Kumer SC, Schmitt TM, Pruett TL.

Transpl Int. 2010 Oct;23(10):1038-44. doi: 10.1111/j.1432-2277.2010.01092.x.

38.

Anti-thymocyte globulin for the treatment of acute cellular rejection following liver transplantation.

Schmitt TM, Phillips M, Sawyer RG, Northup P, Hagspiel KD, Pruett TL, Bonatti HJ.

Dig Dis Sci. 2010 Nov;55(11):3224-34. doi: 10.1007/s10620-010-1149-x. Epub 2010 Mar 18.

PMID:
20238251
39.

Pretransplant predictors of recovery of renal function after liver transplantation.

Northup PG, Argo CK, Bakhru MR, Schmitt TM, Berg CL, Rosner MH.

Liver Transpl. 2010 Apr;16(4):440-6. doi: 10.1002/lt.22008.

40.

T cell receptor gene therapy for cancer.

Schmitt TM, Ragnarsson GB, Greenberg PD.

Hum Gene Ther. 2009 Nov;20(11):1240-8. doi: 10.1089/hum.2009.146. Review.

41.

Fully covered self-expandable metallic stents in the management of complex biliary leaks: preliminary data - a case series.

Wang AY, Ellen K, Berg CL, Schmitt TM, Kahaleh M.

Endoscopy. 2009 Sep;41(9):781-6. doi: 10.1055/s-0029-1215050. Epub 2009 Aug 19.

PMID:
19693751
42.

Temporary placement of fully covered self-expandable metal stents in benign biliary strictures: midterm evaluation (with video).

Mahajan A, Ho H, Sauer B, Phillips MS, Shami VM, Ellen K, Rehan M, Schmitt TM, Kahaleh M.

Gastrointest Endosc. 2009 Aug;70(2):303-9. doi: 10.1016/j.gie.2008.11.029. Epub 2009 Jun 11.

PMID:
19523620
43.

Combined liver-kidney and liver transplantation in patients with renal failure outcomes in the MELD era.

Schmitt TM, Kumer SC, Al-Osaimi A, Shah N, Argo CK, Berg C, Pruett TL, Northup PG.

Transpl Int. 2009 Sep;22(9):876-83. doi: 10.1111/j.1432-2277.2009.00887.x. Epub 2009 Apr 27.

44.

Comparison of three-dimensional rotational angiography and digital subtraction angiography for the evaluation of the liver transplants.

Housseini AM, Bozlar U, Schmitt TM, Bonatti H, Arslan B, Turba UC, Khalil TH, Hagspiel KD.

Clin Imaging. 2009 Mar-Apr;33(2):102-9. doi: 10.1016/j.clinimag.2008.06.031.

PMID:
19237052
45.

Advanced recipient age (>60 years) alone should not be a contraindication to liver retransplantation.

Schmitt TM, Kumer SC, Pruett TL, Argo CK, Northup PG.

Transpl Int. 2009 Jun;22(6):601-5. doi: 10.1111/j.1432-2277.2009.00845.x. Epub 2009 Feb 10.

46.

Long-term outcomes of donation after cardiac death liver allografts from a single center.

Nguyen JH, Bonatti H, Dickson RC, Hewitt WR, Grewal HP, Willingham DL, Harnois DM, Schmitt TM, Machicao VI, Ghabril MS, Keaveny AP, Aranda-Michel J, Satyanarayana R, Rosser BG, Hinder RA, Steers JL, Hughes CB.

Clin Transplant. 2009 Mar-Apr;23(2):168-73. doi: 10.1111/j.1399-0012.2009.00968.x. Epub 2009 Feb 11.

PMID:
19220366
47.

Adoptive immunotherapy of disseminated leukemia with TCR-transduced, CD8+ T cells expressing a known endogenous TCR.

Dossett ML, Teague RM, Schmitt TM, Tan X, Cooper LJ, Pinzon C, Greenberg PD.

Mol Ther. 2009 Apr;17(4):742-9. doi: 10.1038/mt.2008.300. Epub 2009 Feb 10.

48.

Salvage of hyperacute renal transplant hypoperfusion with stent placement: a case report.

Housseini AM, Bozlar U, Bonatti H, Brayman KL, Schmitt TM, Hagspiel KD.

J Vasc Interv Radiol. 2008 Dec;19(12):1761-1764.e2. doi: 10.1016/j.jvir.2008.08.023. Epub 2008 Oct 8.

PMID:
18845455
49.

Benign transient hyperphosphatasemia associated with Epstein-Barr virus enteritis in a pediatric liver transplant patient: a case report.

Hranjec T, Bonatti H, Roman AL, Sifri C, Borowitz SM, Barnes BH, Flohr TR, Pruett TL, Sawyer RG, Schmitt TM.

Transplant Proc. 2008 Jun;40(5):1780-2. doi: 10.1016/j.transproceed.2008.04.011.

50.

Cytomegalovirus glomerulitis in a renal allograft.

Cathro HP, Schmitt TM.

Am J Kidney Dis. 2008 Jul;52(1):188-92. doi: 10.1053/j.ajkd.2008.02.362. Epub 2008 May 12. No abstract available.

PMID:
18468750

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